I. Galea

Most-cited papers

The blood-brain barrier in systemic inflammation.
A. Varatharaj, I. Galea
2017Brain, behavior, and immunity1,074 citations Open access
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The blood–brain barrier in systemic infection and inflammation
I. Galea
2021Cellular & Molecular Immunology682 citations Open access
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Haemoglobin scavenging in intracranial bleeding: biology and clinical implications
D. Bulters, Ben Gaastra, A. Zolnourian, S. Alexander +8 more
2018Nature Reviews Neurology142 citations
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The effect of systemic inflammation on human brain barrier function
Elliot Elwood, Zhi Lim, Hammad Naveed, I. Galea
2017Brain, behavior, and immunity112 citations Open access
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Defining causality in COVID-19 and neurological disorders
M. Ellul, A. Varatharaj, T. Nicholson, T. Pollak +12 more
2020Journal of Neurology Neurosurgery & Psychiatry68 citations Open access
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Relapse in multiple sclerosis
I. Galea, N. Ward-Abel, C. Heesen
2015British medical journal63 citations Open access
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Neuroprotective Role of the Nrf2 Pathway in Subarachnoid Haemorrhage and Its Therapeutic Potential
A. Zolnourian, I. Galea, D. Bulters
2019Oxidative Medicine and Cellular Longevity56 citations Open access
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A subarachnoid haemorrhage-specific outcome tool
A. Pace, Sophie Mitchell, Elizabeth Casselden, A. Zolnourian +4 more
2018Brain : a journal of neurology56 citations Open access
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Spectrum, risk factors and outcomes of neurological and psychiatric complications of COVID-19: a UK-wide cross-sectional surveillance study
A. R. Ross Russell, Marc Hardwick, Athavan Jeyanantham, Laura White +36 more
2021Brain Communications51 citations Open access
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Iron Deposition in the Brain After Aneurysmal Subarachnoid Hemorrhage
I. Galea, A. Durnford, James Glazier, Sophie Mitchell +8 more
2022Stroke50 citations Open access
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Considerations for causality assessment of neurological and neuropsychiatric complications of SARS-CoV-2 vaccines: from cerebral venous sinus thrombosis to functional neurological disorder
M. Butler, A. Tamborska, G. Wood, M. Ellul +8 more
2021Journal of Neurology Neurosurgery & Psychiatry49 citations Open access
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Haemoglobin causes neuronal damage in vivo which is preventable by haptoglobin
P. Garland, Matthew J Morton, W. Haskins, A. Zolnourian +12 more
2020Brain Communications45 citations Open access
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Rethinking the initial changes in subarachnoid haemorrhage: Focusing on real-time metabolism during early brain injury
Yu-Jie Chen, I. Galea, R. L. Macdonald, G. Kwok +2 more
41 citations
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Evidence-based interconversion of the Glasgow Outcome and modified Rankin scales: pitfalls and best practices
Ben Gaastra, D. Ren, S. Alexander, I. Awad +6 more
2022Journal of Stroke & Cerebrovascular Diseases36 citations Open access
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CRP (C-Reactive Protein) in Outcome Prediction After Subarachnoid Hemorrhage and the Role of Machine Learning
Ben Gaastra, Peter Barron, Laura Newitt, Simran Chhugani +5 more
2021Stroke35 citations Open access
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Neurofilament light predicts neurological outcome after subarachnoid haemorrhage
P. Garland, Matthew J Morton, A. Zolnourian, A. Durnford +7 more
2021Brain : a journal of neurology28 citations Open access
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Haptoglobin Treatment for Aneurysmal Subarachnoid Hemorrhage: Review and Expert Consensus on Clinical Translation
I. Galea, Soham Bandyopadhyay, D. Bulters, R. Humar +2 more
2023Stroke25 citations Open access
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Physical activity monitoring to assess disability progression in multiple sclerosis
Charlotte M Stuart, A. Varatharaj, Janine Domjan, Sheaba Philip +1 more
2020Multiple Sclerosis Journal - Experimental, Translational and Clinical24 citations Open access
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Haptoglobin Genotype and Outcome after Subarachnoid Haemorrhage: New Insights from a Meta-Analysis
Ben Gaastra, James Glazier, D. Bulters, I. Galea
2017Oxidative Medicine and Cellular Longevity21 citations Open access
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Real‐world persistence of multiple sclerosis disease‐modifying therapies
E. Tallantyre, Ruth Dobson, Joseph L. J. Froud, Frederika A. St John +25 more
2024European Journal of Neurology19 citations Open access
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The blood-brain interface: a culture change.
I. Galea, V. Perry
2018Brain, behavior, and immunity19 citations Open access
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Pearls & Oy-sters: Resolution of hemichorea following endarterectomy for severe carotid stenosis
I. Galea, F. Norwood, Michael J. Phillips, C. Shearman +2 more
2008Neurology19 citations Open access
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Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UK
J. Blackstone, Thomas Williams, Jennifer M Nicholas, Ekaterina Bordea +58 more
2024BMJ Open18 citations Open access
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Haptoglobin genotype and aneurysmal subarachnoid hemorrhage
Ben Gaastra, D. Ren, S. Alexander, Ellen R. Bennett +17 more
2019Neurology18 citations Open access
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Genetic determinants of circulating haptoglobin concentration
Nabila Kazmi, Y. Koda, N. Ndiaye, S. Visvikis-Siest +3 more
2019Clinica chimica acta; international journal of clinical chemistry17 citations Open access
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Mild Systemic Inflammation Increases Erythrocyte Fragility
Charlotte M Stuart, Carmen Jacob, A. Varatharaj, Sarah Howard +3 more
2024International Journal of Molecular Sciences16 citations Open access
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Long-Term Cognitive Outcome following Aneurysmal Subarachnoid Haemorrhage.
Ben Gaastra, F. Ewbank, W. Tapper, D. Bulters +1 more
2021Journal of Stroke & Cerebrovascular Diseases15 citations Open access
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Risk knowledge of people with relapsing-remitting multiple sclerosis – Results of an international survey
A. Giordano, Katrin Liethmann, S. Köpke, J. Poettgen +10 more
2018PLoS ONE15 citations Open access
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Red Blood Cells in the Cerebrospinal Fluid Compartment After Subarachnoid Haemorrhage: Significance and Emerging Therapeutic Strategies
S. Bandyopadhyay, N. Schwendinger, B. R. Jahromi, S. Lad +5 more
2024Translational Stroke Research14 citations Open access
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Zonulin and blood–brain barrier permeability are dissociated in humans
Charlotte M Stuart, A. Varatharaj, M. E. Winberg, P. Galéa +7 more
2022Clinical and Translational Medicine14 citations Open access
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Long‐term fatigue following aneurysmal subarachnoid haemorrhage and the impact on employment
Ben Gaastra, Harry Carmichael, I. Galea, D. Bulters
2022European Journal of Neurology14 citations Open access
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Haptoglobin genotype and outcome after aneurysmal subarachnoid haemorrhage
Matthew J Morton, I. Hostettler, Nabila Kazmi, V. Alg +14 more
2020Journal of Neurology Neurosurgery & Psychiatry13 citations Open access
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Duration and characteristics of persistent headache following aneurysmal subarachnoid hemorrhage
Ben Gaastra, Harry Carmichael, I. Galea, D. Bulters
2022Headache11 citations Open access
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Lymphopenia in treatment-naive relapsing multiple sclerosis
Zhi Lim, Elliot Elwood, Hammad Naveed, I. Galea
2016Neurology: Neuroimmunology & Neuroinflammation11 citations Open access
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Viral Infection and the Blood-Brain Barrier: Molecular Research Insights and Therapies
S. Boardman, Claire Hetherington, Thomas Hughes, C. Cook +11 more
2025Journal of Infectious Diseases10 citations Open access
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A Randomised Controlled Trial of SFX-01 After Subarachnoid Haemorrhage — The SAS Study
A. Zolnourian, Patrick Garland, P. Holton, Mukul Arora +7 more
2024Translational Stroke Research10 citations Open access
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SFX-01 reduces residual disability after experimental autoimmune encephalomyelitis.
I. Galea, I. Copple, D. Howat, Stephen Franklin
2019Multiple Sclerosis and Related Disorders10 citations Open access
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Functional effects of haemoglobin can be rescued by haptoglobin in an in vitro model of subarachnoid haemorrhage
Hannah Warming, K. Deinhardt, P. Garland, J. More +3 more
2023bioRxiv9 citations Open access
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Risk–benefit analysis of COVID-19 vaccines — a neurological perspective
Colleen L. Lau, I. Galea
2021Nature Reviews Neurology9 citations Open access
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Gadolinium enhancement of cranial nerves: Implications for interstitial fluid drainage from brainstem into cranial nerves in humans
A. Varatharaj, R. Carare, R. Weller, M. Gawne-Cain +1 more
2021Proceedings of the National Academy of Sciences of the United States of America9 citations Open access
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Cervical spinal degenerative disease in multiple sclerosis
Simran Chhugani, Nivedita Agarwal, F. Sheikh, F. Borca +2 more
2021European Journal of Neurology9 citations Open access
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Do people with multiple sclerosis want to discuss their long-term prognosis? A nationwide study in Argentina.
Edgar Carnero Contentti, P. López, J. P. Pettinicchi, R. Alonso +4 more
2020Multiple Sclerosis and Related Disorders9 citations Open access
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Hearing impairment after subarachnoid hemorrhage
Nicci Campbell, C. Verschuur, Sophie Mitchell, Orlaith McCaffrey +9 more
2019Annals of Clinical and Translational Neurology9 citations Open access
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Systemic inflammation associates with and precedes cord atrophy in progressive multiple sclerosis
Charlotte M Stuart, A. Varatharaj, Yukai Zou, A. Darekar +4 more
2024Brain Communications8 citations Open access
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The Haptoglobin Response after Aneurysmal Subarachnoid Haemorrhage
S. Bandyopadhyay, Patrick Garland, Ben Gaastra, A. Zolnourian +2 more
2023International Journal of Molecular Sciences8 citations Open access
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Association of Haptoglobin Phenotype With Neurological and Cognitive Outcomes in Patients With Subarachnoid Hemorrhage
Sung-Woo Han, B. Kim, Tae Yeon Kim, Seung Hyuk Lim +9 more
2022Frontiers in Aging Neuroscience8 citations Open access
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A Genome-Wide Association Study of Outcome After Aneurysmal Subarachnoid Haemorrhage: Discovery Analysis
Ben Gaastra, S. Alexander, M. Bakker, H. Bhagat +21 more
2022Translational Stroke Research7 citations Open access
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Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage
Ben Gaastra, P. Duncan, M. Bakker, I. Hostettler +7 more
2022European Journal of Neurology7 citations Open access
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Prognostic information for people with MS: Impossible or inevitable?
C. Heesen, A. Scalfari, I. Galea
2018Multiple Sclerosis7 citations Open access
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The intrathecal CD163-haptoglobin–hemoglobin scavenging system in subarachnoid hemorrhage
J. Galea, G. Cruickshank, J. Teeling, D. Boche +3 more
2012Journal of Neurochemistry7 citations Open access
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