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John N. Brewin · SciRah

Researcher profile · Semantic Scholar

John N. Brewin

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John N. Brewin — researcher profile on SciRah

h-index: 13
Works: 48
Citations: 540

Most-cited papers

Determinants of severity in sickle cell disease.
D. Rees, V. Brousse, John N. Brewin
2022Blood reviews75 citations Open access
Semantic Scholar
Oxidative stress and phosphatidylserine exposure in red cells from patients with sickle cell anaemia
A. Hannemann, D. Rees, John N. Brewin, A. Noè +2 more
2018British Journal of Haematology39 citations Open access
Semantic Scholar
The Effect of Antioxidants on the Properties of Red Blood Cells From Patients With Sickle Cell Anemia
Halima W. M. Al Balushi, A. Hannemann, D. Rees, John N. Brewin +1 more
2019Frontiers in Physiology37 citations Open access
Semantic Scholar
A gain of function variant in PIEZO1 (E756del) and sickle cell disease
H. Rooks, John N. Brewin, K. Gardner, S. Chakravorty +4 more
2018Haematologica29 citations Open access
Semantic Scholar
Red blood cell mannoses as phagocytic ligands mediating both sickle cell anaemia and malaria resistance
Huan Cao, A. Antonopoulos, Sadie Henderson, Heather J. Wassall +24 more
2021Nature Communications27 citations Open access
Semantic Scholar
Yoda1 and phosphatidylserine exposure in red cells from patients with sickle cell anaemia
R. Wadud, A. Hannemann, David C. Rees, John N. Brewin +1 more
2020Scientific Reports24 citations Open access
Semantic Scholar
Proteomic analysis of plasma from children with sickle cell anemia and silent cerebral infarction
S. Tewari, George Renney, John N. Brewin, K. Gardner +7 more
2018Haematologica21 citations Open access
Semantic Scholar
The significance of spleen size in children with sickle cell anemia
A. Nardo-Marino, A. Glenthøj, John N. Brewin, J. Petersen +4 more
2022American journal of hematology/oncology16 citations Open access
Semantic Scholar
Automating Pitted Red Blood Cell Counts Using Deep Neural Network Analysis: A New Method for Measuring Splenic Function in Sickle Cell Anaemia
A. Nardo-Marino, T. Braunstein, J. Petersen, John N. Brewin +5 more
2022Frontiers in Physiology16 citations Open access
Semantic Scholar
Oxygen gradient ektacytometry does not predict pain in children with sickle cell anaemia
A. Nardo-Marino, J. Petersen, John N. Brewin, H. Birgens +4 more
2021British Journal of Haematology14 citations Open access
Semantic Scholar
A novel index to evaluate ineffective erythropoiesis in hematological diseases offers insights into sickle cell disease
John N. Brewin, Sara El Hoss, J. Strouboulis, D. Rees
2021Haematologica14 citations Open access
Semantic Scholar
Genome wide association study of silent cerebral infarction in sickle cell disease (HbSS and HbSC)
John N. Brewin, H. Rooks, K. Gardner, H. Senior +7 more
2020Haematologica14 citations Open access
Semantic Scholar
Males with sickle cell disease have higher risks of cerebrovascular disease, increased inflammation, and a reduced response to hydroxyurea
M. di Mauro, Sara El Hoss, A. Nardo-Marino, S. Stuart-Smith +4 more
2023American journal of hematology/oncology13 citations Open access
Semantic Scholar
The genetic dissection of fetal haemoglobin persistence in sickle cell disease in Nigeria
Oyesola O. Ojewunmi, T. Adeyemo, A. I. Oyetunji, B. Inyang +31 more
2023medRxiv13 citations Open access
Semantic Scholar
The pleiotropic effects of α‐thalassemia on HbSS and HbSC sickle cell disease: Reduced erythrocyte cation co‐transport activity, serum erythropoietin, and transfusion burden, do not translate into increased survival
John N. Brewin, A. Nardo-Marino, S. Stuart-Smith, Sara El Hoss +5 more
2022American journal of hematology/oncology13 citations Open access
Semantic Scholar
Early Markers of Sickle Nephropathy in Children With Sickle Cell Anemia Are Associated With Red Cell Cation Transport Activity
John N. Brewin, S. Tewari, A. Hannemann, Halima W. M. Al Balushi +3 more
2017HemaSphere13 citations Open access
Semantic Scholar
DNMT3A: the DioNysian MonsTer of acute myeloid leukaemia
E. O'brien, John N. Brewin, T. Chevassut
2014Therapeutic Advances in Hematology13 citations Open access
Semantic Scholar
Rapid detection of DNMT3A R882 codon mutations allows early identification of poor risk patients with acute myeloid leukemia
John N. Brewin, G. Horne, Kathrin E Bisling, Helen J. S. Stewart +1 more
2013Leukemia and Lymphoma13 citations Open access
Semantic Scholar
The erythrocyte membrane properties of beta thalassaemia heterozygotes and their consequences for Plasmodium falciparum invasion
Viola Introini, A. Marín-Menéndez, Guilherme Nettesheim, Yen-Chun Lin +8 more
2022Scientific Reports12 citations Open access
Semantic Scholar
Evaluation of oxidative stress-related genetic variants for predicting stroke in patients with sickle cell anemia.
I. Domingos, D. Pereira-Martins, R. Borges-Medeiros, D. A. Falcão +16 more
2020Journal of Neurological Sciences12 citations
Semantic Scholar
Genetic Analysis of Patients With Sickle Cell Anemia and Stroke Before 4 Years of Age Suggest an Important Role for Apoliprotein E
John N. Brewin, Alexander Smith, Riley Cook, S. Tewari +6 more
2020Circulation Genomic and Precision Medicine10 citations
Semantic Scholar
The effects of hydroxycarbamide on the plasma proteome of children with sickle cell anaemia
John N. Brewin, S. Tewari, S. Menzel, F. Kirkham +4 more
2019British Journal of Haematology10 citations Open access
Semantic Scholar
How I manage sickle cell patients with high transcranial doppler results
John N. Brewin, B. Kaya, S. Chakravorty
2017British Journal of Haematology10 citations
Semantic Scholar
DNMT3A mutations at R882 hotspot are only found in major clones of acute myeloid leukemia
Kathrin E Bisling, John N. Brewin, A. McGovern, G. Horne +4 more
2014Leukemia and Lymphoma10 citations Open access
Semantic Scholar
Nanoscale adhesion profiling and membrane characterisation in sickle cell disease using hybrid atomic force microscopy-IR spectroscopy.
Alexander Paul Fellows, M. Casford, P. Davies, John S. Gibson +2 more
2020Colloids and Surfaces B: Biointerfaces9 citations Open access
Semantic Scholar
Reduced GATA1 levels are associated with ineffective erythropoiesis in sickle cell anemia
Sara El Hoss, P. Shangaris, John N. Brewin, Maria Eleni Psychogyiou +10 more
2024Haematologica8 citations Open access
Semantic Scholar
The effect of the antisickling compound GBT1118 on the permeability of red blood cells from patients with sickle cell anemia
Halima W. M. Al Balushi, K. Dufu, D. Rees, John N. Brewin +4 more
2019Physiological Reports8 citations Open access
Semantic Scholar
The super sickling haemoglobin HbS‐Oman: a study of red cell sickling, K+ permeability and associations with disease severity in patients heterozygous for HbA and HbS‐Oman (HbA/S‐Oman genotype)
Halima W. M. Al Balushi, Y. Wali, Maha Al-Awadi, T. Al-Subhi +4 more
2017British Journal of Haematology8 citations
Semantic Scholar
The role of WNK in modulation of KCl cotransport activity in red cells from normal individuals and patients with sickle cell anaemia
David C.-Y. Lu, A. Hannemann, R. Wadud, D. Rees +3 more
2019Pflügers Archiv: European Journal of Physiology6 citations Open access
Semantic Scholar
Genetic profiling in acute myeloid leukemia.
G. Horne, John N. Brewin, T. Chevassut
2012New England Journal of Medicine6 citations Open access
Semantic Scholar
Measurement of erythrocyte membrane mannoses to assess splenic function
Huan Cao, A. Mathur, Charlotte Robertson, A. Antonopoulos +10 more
2022British Journal of Haematology5 citations Open access
Semantic Scholar
Catheter associated thromboses in patients with sickle cell anaemia and dual lumen Vortex apheresis ports are common and can be clinically asymptomatic
John N. Brewin, M. Crowley, R. Kesse-Adu, S. Stuart-Smith +2 more
2020British Journal of Haematology5 citations Open access
Semantic Scholar
Oxidative Stress and Haemolytic Anaemia In Dogs and Cats: A Comparative Approach
J. Gibson, R. Wadud, Chunfeng Lu, John N. Brewin +1 more
2019Integrative Journal of Veterinary Biosciences4 citations Open access
Semantic Scholar
Iron deficiency is associated with reduced levels of inflammation and haemolysis in patients with HbSS and HbSC and reduced clinical admissions in those with HbSC
Simone Villaboni, S. Stuart-Smith, Arne de Kreuk, David C. Rees +1 more
2025British Journal of Haematology3 citations
Semantic Scholar
Pathophysiological Relevance of Renal Medullary Conditions on the Behaviour of Red Cells From Patients With Sickle Cell Anaemia
David C.-Y. Lu, R. Wadud, A. Hannemann, D. Rees +2 more
2021Frontiers in Physiology3 citations Open access
Semantic Scholar
Francis Andrew Brewin, “He Who Would Valiant Be”: The Makings of a Canadian Anglican Christian Socialist
John N. Brewin
2000Historical Papers3 citations Open access
Semantic Scholar
The effect of xanthine oxidase and hypoxanthine on the permeability of red cells from patients with sickle cell anemia
Halima W. M. Al Balushi, D. Rees, John N. Brewin, A. Hannemann +1 more
2018Physiological Reports2 citations Open access
Semantic Scholar
Sickle cell disease: An update on management
John N. Brewin, J. Howard
20172 citations
Semantic Scholar
Decreased Red Blood Cell Deformability Contributes to Loss of Splenic Filtration Function and Variations in Spleen Size in Children with Sickle Cell Anaemia
A. Nardo-Marino, A. Glenthøj, John N. Brewin, J. Petersen +4 more
2022Blood1 citations Open access
Semantic Scholar
Hemoglobin S Induces Exposure of Red Blood Cell Membrane Skeleton Microdomains Bearing Mannose That Stimulate Phagocytosis By Macrophages: A Molecular Basis for Hemolysis in Sickle Cell Disease but Protection Against Plasmodium Falciparum malaria
Huan Cao, Heather J. Wassall, Megan A Forrester, L. Hall +16 more
2018Blood1 citations Open access
Semantic Scholar
Utilising Patient-Reported Experience Measures to Drive Healthcare Improvements: The Application of Validated PREM Survey Tools in a Haemoglobinopathy Network in South London
Subarna Chakravorty, Jesufikunayomi Ifeoluwa, M. Awogbade, Samah Babiker +18 more
2024Blood0 citations
Semantic Scholar
Tuesday 10 October 2023 Sig Session
Sara El Hoss, P. Shangaris, John N. Brewin, Maria Eleni Psychogyiou +5 more
2023Transfusion Medicine0 citations Open access
Semantic Scholar
S269: MALE PATIENTS WITH SCD HAVE A HIGHER RISK OF CEREBROVASCULAR DISEASE, INCREASED INFLAMMATORY MARKERS, AND POORER RESPONSE TO HYDROXYUREA
M. di Mauro, A. Nardo-Marino, S. Stuart-Smith, Sara El Hoss +5 more
2023HemaSphere0 citations Open access
Semantic Scholar
Unravelling the Mechanism behind Ineffective Erythropoiesis in Sickle Cell Disease: The Role of GATA-1
Sara El Hoss, P. Shangaris, John N. Brewin, Maria Eleni Psychogyiou +5 more
2023Blood0 citations
Semantic Scholar
Using AFM-Nano IR Spectroscopy and Sum-Frequency Generation (SFG) Vibrational Spectroscopy to Investigate Sickle Cell Disease
Alexander Paul Fellows, M. Casford, John N. Brewin, D. Rees +2 more
20200 citations Open access
Semantic Scholar
High mannose N-glycans on red blood cells as phagocytic ligands, mediating both sickle cell anaemia and resistance to malaria
Huan Cao, A. Antonopoulos, Sadie Henderson, Heather J. Wassall +24 more
2020bioRxiv0 citations Open access
Semantic Scholar
Red Blood Cell Deformability Demonstrated with the Oxygenscan: Exploring the Association with Hydroxyurea Treatment, Co-Inherited α-Thalassemia, and Frequency of Pain in Children with Sickle Cell Anemia
A. Nardo-Marino, J. Petersen, A. Glenthoej, John N. Brewin +4 more
2019Blood0 citations Open access
Semantic Scholar
Whole Exome Sequencing in Children with Sickle Cell Anemia Who Developed Ischemic Stroke Prior to 4 Years of Age Reveals a Strong Association with Inherited Dyslipidemias
John N. Brewin, Riley Cook, Alexander Smith, V. Brousse +5 more
2019Blood0 citations Open access
Semantic Scholar

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D. Rees×28
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A. Hannemann×10
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S. Menzel×8
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A. Nardo-Marino

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Halima W. M. Al Balushi×5

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S. Tewari — researcher profile on SciRah

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