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A. Darekar · SciRah

Researcher profile · Semantic Scholar

A. Darekar

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A. Darekar — researcher profile on SciRah

h-index: 18
Works: 49
Citations: 1,583

Most-cited papers

Comparison of Different Algorithms for Predicting Clinical Drug-Drug Interactions, Based on the Use of CYP3A4 in Vitro Data: Predictions of Compounds as Precipitants of Interaction
O. Fahmi, S. Hurst, D. Plowchalk, J. Cook +7 more
2009Drug Metabolism And Disposition229 citations
Semantic Scholar
Effect of ertugliflozin on glucose control, body weight, blood pressure and bone density in type 2 diabetes mellitus inadequately controlled on metformin monotherapy (VERTIS MET)
J. Rosenstock, J. Frias, D. Páll, B. Charbonnel +7 more
2018Diabetes, obesity and metabolism167 citations Open access
Semantic Scholar
Proof of concept trial of tanezumab for the treatment of symptoms associated with interstitial cystitis.
Robert J. Evans, R. Moldwin, N. Cossons, A. Darekar +2 more
2011Journal of Urology158 citations
Semantic Scholar
Phase III, efficacy and safety study of ertugliflozin monotherapy in people with type 2 diabetes mellitus inadequately controlled with diet and exercise alone
S. Terra, K. Focht, M. Davies, J. Frias +7 more
2017Diabetes, obesity and metabolism146 citations
Semantic Scholar
Flexible‐Dose Fesoterodine in Elderly Adults with Overactive Bladder: Results of the Randomized, Double‐Blind, Placebo‐Controlled Study of Fesoterodine in an Aging Population Trial
A. Wagg, V. Khullar, D. Marschall-Kehrel, M. Michel +5 more
2013Journal of The American Geriatrics Society109 citations
Semantic Scholar
Application of CYP3A4 in vitro data to predict clinical drug-drug interactions; predictions of compounds as objects of interaction.
K. Youdim, Aref L. Zayed, M. Dickins, A. Phipps +9 more
2008British Journal of Clinical Pharmacology100 citations Open access
Semantic Scholar
Long‐term efficacy and safety of ertugliflozin monotherapy in patients with inadequately controlled T2DM despite diet and exercise: VERTIS MONO extension study
R. Aronson, J. Frias, A. Goldman, A. Darekar +2 more
2018Diabetes, obesity and metabolism94 citations Open access
Semantic Scholar
Cognitive testing in early-phase clinical trials: Development of a rapid computerized test battery and application in a simulated Phase I study
A. Collie, A. Darekar, G. Weissgerber, M. Toh +3 more
200780 citations
Semantic Scholar
Long‐term efficacy and safety of ertugliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin monotherapy: 104‐week VERTIS MET trial
Silvina Gallo, B. Charbonnel, A. Goldman, Harry Shi +4 more
2019Diabetes, obesity and metabolism68 citations Open access
Semantic Scholar
Evaluation of Cognitive Function in Healthy Older Subjects Treated with Fesoterodine
G. Kay, P. Maruff, D. Scholfield, B. Malhotra +3 more
2012Postgraduate medicine68 citations
Semantic Scholar
Long‐term safety, tolerability and efficacy of flexible‐dose fesoterodine in elderly patients with overactive bladder: Open‐label extension of the SOFIA trial
A. Wagg, V. Khullar, Martin C. Michel, M. Oelke +2 more
2014Neurourology and Urodynamics54 citations
Semantic Scholar
Investigation of the clinical efficacy and safety of pregabalin alone or combined with tolterodine in female subjects with idiopathic overactive bladder
J. Marencak, N. Cossons, A. Darekar, Ian W. Mills
2011Neurourology and Urodynamics36 citations
Semantic Scholar
Efficacy and safety of ervogastat alone and in combination with clesacostat in patients with biopsy-confirmed metabolic dysfunction-associated steatohepatitis and F2-F3 fibrosis (MIRNA): results from a phase 2, randomised, double-blind, double-dummy study.
V. Wong, Neeta B. Amin, Hirokazu Takahashi, A. Darekar +7 more
2025The Lancet Gastroenterology and Hepatology28 citations
Semantic Scholar
Safety and efficacy of flexible-dose fesoterodine in British subjects with overactive bladder: insights into factors associated with dose escalation
L. Cardozo, T. Hall, J. Ryan, C. Ebel-Bitoun +3 more
2012International Urogynecology Journal27 citations
Semantic Scholar
Measurement of urethral closure function in women with stress urinary incontinence.
N. Klarskov, D. Scholfield, K. Soma, A. Darekar +2 more
2009Journal of Urology25 citations
Semantic Scholar
Dose-escalating study of the pharmacokinetics and tolerability of fesoterodine in children with overactive bladder.
B. Malhotra, A. El-Tahtawy, E. Wang, A. Darekar +4 more
2012Journal of Pediatric Urology24 citations
Semantic Scholar
Cognitive testing in early phase clinical trials: outcome according to adverse event profile in a Phase I study
A. Collie, P. Maruff, Peter J. Snyder, A. Darekar +1 more
2006Human psychopharmacology24 citations
Semantic Scholar
Efficacy of ertugliflozin in monotherapy or combination therapy in patients with type 2 diabetes: A pooled analysis of placebo-controlled studies
Jie Liu, L. Tarasenko, S. Terra, S. Huyck +6 more
2019Diabetes & vascular disease research22 citations Open access
Semantic Scholar
Effect of ertugliflozin on blood pressure in patients with type 2 diabetes mellitus: a post hoc pooled analysis of randomized controlled trials
Jie Liu, A. Pong, Silvina Gallo, A. Darekar +1 more
2019Cardiovascular Diabetology18 citations Open access
Semantic Scholar
Factors associated with dose escalation of fesoterodine for treatment of overactive bladder in people >65 years of age: A post hoc analysis of data from the SOFIA study
A. Wagg, A. Darekar, D. Arumí, V. Khullar +1 more
2015Neurourology and Urodynamics12 citations
Semantic Scholar
Current pressure on the UK imaging workforce deters imaging research in the NHS and requires urgent attention.
J. Rodrigues, T. O'Regan, A. Darekar, S. Taylor +1 more
2022Clinical Radiology10 citations Open access
Semantic Scholar
Effect of fesoterodine on urethral closure function in women with stress urinary incontinence assessed by urethral pressure reflectometry
N. Klarskov, A. Darekar, D. Scholfield, L. Whelan +1 more
2014International Urogynecology Journal9 citations
Semantic Scholar
Effects of drug cessation after flexible‐dose fesoterodine in patients with overactive bladder
V. Khullar, L. Cardozo, C. Kelleher, T. Hall +5 more
2013BJU International9 citations
Semantic Scholar
A PHASE 2, 8-WEEK, MULTI-CENTER, RANDOMIZED DOUBLE- BLIND, PLACEBO CONTROLLED, PARALLEL GROUP STUDY EVALUATING THE EFFICACY, TOLERABILITY AND SAFETY OF [S,S] - REBOXETINE (PNU-165442G) FOR STRESS URINARY INCONTINENCE IN WOMEN
N. Zinner, D. Scholfield, K. Soma, A. Darekar +2 more
20089 citations
Semantic Scholar
Efficacy and safety of ertugliflozin in East/Southeast Asian patients with type 2 diabetes mellitus
Jie Liu, Shrita M. Patel, N. Cater, Larry Wu +6 more
2019Diabetes, obesity and metabolism8 citations Open access
Semantic Scholar
880 ASSESSMENT OF FESOTERODINE TREATMENT IN OLDER PEOPLE WITH OVERACTIVE BLADDER: RESULTS OF SOFIA, A DOUBLE-BLIND, PLACEBO- CONTROLLED PAN EUROPEAN TRIAL
A. Wagg, V. Khullar, D. Marschall-Kehrel, M. Michel +6 more
20118 citations
Semantic Scholar
Development of a predictive model for urgency urinary incontinence.
A. Darekar, M. Carlsson, Sheila Quinn, F. Ntanios +3 more
2016Contemporary Clinical Trials7 citations
Semantic Scholar
EVALUATION OF THE SENSITIVITY OF URETHRAL PRESSURE REFLECTOMETRY (UPR) AND URETHRAL PRESSURE PROFILOMETRY (UPP) TO DETECT PHARMACOLOGICAL AUGMENTATION OF URETHRAL PRESSURE, USING [S,S]-REBOXETINE
N. Klarskov, D. Scholfield, K. Soma, A. Darekar +2 more
20087 citations
Semantic Scholar
Evaluation of Cognitive Function in Healthy Older Adults Treated With Fesoterodine
G. Kay, P. Maruff, D. Scholfield, B. Malhotra +3 more
20116 citations
Semantic Scholar
Fesoterodine treatment of pediatric patients with neurogenic detrusor overactivity: A 24-week, randomized, open-label, phase 3 study.
T. Kitta, A. Darekar, B. Malhotra, Mohamed H. Shahin +5 more
2022Journal of Pediatric Urology5 citations
Semantic Scholar
Reproducibility of Biomarkers in MASLD: A Benchmark for Clinically Meaningful Change in Serially Measured Non-Invasive Tests.
Tsz-Yuen Au, A. Darekar, V. Wong, J. Foucquier +3 more
2026Journal of Hepatology3 citations Open access
Semantic Scholar
NIHR Imaging Group. Who are we and what do we do?
S. Taylor, A. Darekar, V. Goh, S. Neubauer +2 more
2023Clinical Radiology2 citations Open access
Semantic Scholar
Population Pharmacokinetic and Pharmacodynamic Modeling of Fesoterodine in Pediatric Patients with Neurogenic Detrusor Overactivity
Yamato Sano, S. Shoji, Mohamed Shahin, K. Sweeney +2 more
2023European journal of drug metabolism and pharmacokinetics1 citations Open access
Semantic Scholar
Long-Term Efficacy and Safety of Ertugliflozin in Patients (Pts) with Type 2 Diabetes Mellitus (T2DM) Inadequately Controlled with Metformin (MET) Monotherapy—104-Week VERTIS MET Trial
Silvina Gallo, B. Charbonnel, A. Goldman, Harry Shi +4 more
2018Diabetes1 citations
Semantic Scholar
578 Effect of treatment response on the decision to escalate antimuscarinic dose in elderly subjects with overactive bladder
A. Wagg, V. Khullar, M. Oelke, D. Marschall-Kehrel +3 more
20121 citations
Semantic Scholar
Efficacy and Tolerability of Fesoterodine in Older People With Overactive Bladder: Results of the Open-Label Phase of the SOFIA Trial
A. Wagg, V. Khullar, D. Marschall-Kehrel, M. Michel +5 more
20111 citations
Semantic Scholar
A randomized study to assess the action of fesoterodine on urethral function in women with stress urinary incontinence using urethral pressure reflectometry
N. Klarskov, A. Darekar, D. Scholfield, L. Whelan +1 more
20111 citations
Semantic Scholar
Urethral pressure reflectometry is valuable for evaluating pharmacological therapies for stress urinary incontinence.
N. Klarskov, D. Scholfield, A. Darekar, M. Christensen +1 more
20101 citations
Semantic Scholar
IMPROVEMENT IN INCONTINENCE QUALITY OF LIFE (I-QOL) AND PATIENT GLOBAL IMPRESSION OF CHANGE (PGIC) MEASURES IN WOMEN WITH STRESS URINARY INCONTINENCE (SUI) FOLLOWING TREATMENT WITH [S,S] - REBOXETINE (SSRBX)
N. Zinner, D. Scholfield, K. Soma, A. Darekar +2 more
20081 citations
Semantic Scholar
P.1.f.001 Cognitive testing in early-phase clinical trials: development of a rapid computerized test battery and application in a simulated Phase I study
A. Collie, A. Darekar, P. Maruff, Peter J. Snyder +1 more
20061 citations
Semantic Scholar
Dose Selection for Ceftibuten Combined with Avibactam Tomilopil, a Potential Oral Alternative to Carbapenems for Patients with Complicated Urinary Tract Infections
Siddhee A. Sahasrabudhe, Satoshi Shoji, Abhijeet S. Jakate, B. Abraham +10 more
2026Journal of clinical pharmacology0 citations Open access
Semantic Scholar
Reply to: "Confounded time intervals and artificial variance suppression in MASLD biomarker reproducibility".
A. Darekar, V. Wong, Quentin M. Anstee
2026Journal of Hepatology0 citations
Semantic Scholar
EFFECTS OF ERTUGLIFLOZIN ON BLOOD PRESSURE AND PULSE RATE IN PATIENTS WITH TYPE 2 DIABETES MELLITUS
Jie Liu, A. Pong, Silvina Gallo, A. Darekar +2 more
20180 citations Open access
Semantic Scholar
Monotherapy in Patients with Type 2 Diabetes Mellitus Inadequately Controlled with Diet and Exercise Alone
S. Terra, K. Focht, M. Davies, J. Frias +7 more
20170 citations
Semantic Scholar
510 Evaluation of pharmacokinetics (PK) and safety of fesoterodine 4-and 8-mg once-daily in an 8-week study in pediatric patients with overactive bladder (OAB)
B. Malhotra, A. El-Tahtawy, E. Wang, A. Darekar +3 more
20120 citations
Semantic Scholar
Effects of Drug Cessation in Subjects Receiving Fesoterodine for Treatment of Overactive Bladder Symptoms
L. Cardozo, J. Ryan, T. Hall, C. E. Bitoun +5 more
20110 citations
Semantic Scholar
Does Fesoterodine Provide Efficacy, Tolerability, and Treatment Satisfaction? A Study of British Patients with the Overactive Bladder Syndrome
L. Cardozo, T. Hall, J. Ryan, C. E. Bitoun +2 more
20100 citations
Semantic Scholar
1508 TANEZUMAB REDUCES PAIN AND URGENCY IN INTERSTITIAL CYSTITIS: RESULTS OF A PHASE 2 TRIAL
R. Evans, R. Moldwin, N. Cossons, A. Darekar +2 more
20100 citations
Semantic Scholar
639 EFFICACY AND SAFETY OF TANEZUMAB FOR THE TREATMENT OF INTERSTITIAL CYSTITIS
R. Moldwin, R. Evans, N. Cossons, A. Darekar +2 more
20100 citations
Semantic Scholar

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D. Scholfield×15
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D. Scholfield — researcher profile on SciRah
S. Terra×10
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S. Terra — researcher profile on SciRah
A. Wagg×10
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A. Wagg — researcher profile on SciRah
V. Khullar×8
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V. Khullar — researcher profile on SciRah

×7

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Brett Lauring — researcher profile on SciRah

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M. Oelke — researcher profile on SciRah

C. E. Bitoun×6

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C. E. Bitoun — researcher profile on SciRah

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B. Malhotra — researcher profile on SciRah

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S. Huyck — researcher profile on SciRah

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N. Cossons — researcher profile on SciRah

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P. Maruff — researcher profile on SciRah

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Silvina Gallo — researcher profile on SciRah