M. Kho

Most-cited papers

1. Sleep duration and health in adults: an overview of systematic reviews.

   J. Chaput, Caroline Dutil, Ryan B. Featherstone, R. Ross +7 more

   2020Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme321 citations Open access

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2. A Focused Update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Anxiety, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU

   Kimberley Lewis, M. Balas, Joanna L. Stollings, Molly McNett +20 more

   2025Critical Care Medicine216 citations Open access

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3. A systematic review of compositional data analysis studies examining associations between sleep, sedentary behaviour, and physical activity with health outcomes in adults.

   I. Janssen, Anna E. Clarke, V. Carson, J. Chaput +7 more

   2020Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme193 citations Open access

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4. Early In-Bed Cycle Ergometry With Critically Ill, Mechanically Ventilated Patients: Statistical Analysis Plan for CYCLE (Critical Care Cycling to Improve Lower Extremity Strength), an International, Multicenter, Randomized Clinical Trial

   D. Heels-Ansdell, L. Kelly, H. O'Grady, Chris Farley +25 more

   2024JMIR Research Protocols132 citations Open access

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5. Restricted visitation policies in acute care settings during the COVID-19 pandemic: a scoping review

   S. Moss, Karla D. Krewulak, H. Stelfox, Sofia B. Ahmed +26 more

   2021Critical Care82 citations Open access

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6. COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

   Sheryl Ann Ryuzo Laurent Lara Andrew Shingo Elisabeth Dia Abdukahil Abe Abel Absil Acker Adachi Adam Adrião , S. Abdukahil, Ryuzo Abe, Laurent Abel +496 more

   2021Infection75 citations Open access

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7. Frailty, Outcomes, Recovery and Care Steps of Critically Ill Patients (FORECAST): a prospective, multi-centre, cohort study

   J. Muscedere, S. Bagshaw, M. Kho, S. Mehta +15 more

   2024Intensive Care Medicine66 citations Open access

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8. Venous Thromboembolism Prophylaxis in Critically Ill Adults - A Systematic Review and Network Meta-Analysis.

   S. Fernando, Alexandre Tran, Wei Cheng, B. Sadeghirad +15 more

   2021Chest66 citations

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9. Characteristics and outcomes of patients with COVID-19 admitted to hospital and intensive care in the first phase of the pandemic in Canada: a national cohort study

   S. Murthy, P. Archambault, A. Atique, F. Carrier +43 more

   2021CMAJ Open64 citations Open access

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10. Physiotherapy management for COVID-19 in the acute hospital setting and beyond: an update to clinical practice recommendations

    P. Thomas, C. Baldwin, L. Beach, Bernie Bissett +13 more

    2021Journal of Physiotherapy63 citations Open access

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11. Clinical characteristics, risk factors and outcomes in patients with severe COVID-19 registered in the International Severe Acute Respiratory and Emerging Infection Consortium WHO clinical characterisation protocol: a prospective, multinational, multicentre, observational study

    L. Reyes, S. Murthy, Esteban Garcia-Gallo, M. Irvine +49 more

    2021ERJ Open Research46 citations Open access

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12. The sit-to-stand test as a patient-centered functional outcome for critical care research: a pooled analysis of five international rehabilitation studies

    H. O'Grady, L. Edbrooke, Chris Farley, S. Berney +24 more

    2022Critical Care35 citations Open access

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13. Early In-Bed Cycle Ergometry in Mechanically Ventilated Patients.

    M. Kho, Susan Berney, A. Pastva, L. Kelly +29 more

    2024NEJM Evidence34 citations

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14. The value of open-source clinical science in pandemic response: lessons from ISARIC

    Ali Sheryl Ann Nurul Najmee Ryuzo Laurent Lara Subhash Abbas Abdukahil Abdulkadir Abe Abel Absil Acharya , A. Abbas, S. Abdukahil, Nurul Najmee Abdulkadir +496 more

    2021Lancet. Infectious Diseases (Print)34 citations Open access

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15. The intensive care medicine research agenda for the management of ICU acquired weakness: a multinational, interprofessional perspective

    Sabrina Eggmann, S. Parry, Tessa Broadley, G. S. Lynch +47 more

    2025Intensive Care Medicine30 citations Open access

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16. Sex and gender-based analysis and diversity metric reporting in acute care trials published in high-impact journals: a systematic review

    D. Granton, Myanca Rodrigues, V. Raparelli, K. Honarmand +22 more

    2024BMJ Open22 citations Open access

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17. Early Rehabilitation in Critically ill Children: A Two Center Implementation Study*

    K. Choong, Douglas D. Fraser, A. Al-Farsi, Saif Awlad Thani +18 more

    2024Pediatric Critical Care Medicine21 citations Open access

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18. Physical rehabilitation in the intensive care unit: past, present, and future

    M. Kho, S. Berney, B. Connolly

    2023Intensive Care Medicine19 citations

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19. Non-pharmacological Management of Non-productive Chronic Cough in Adults: A Systematic Review

    A. Ilicic, Ana Oliveira, Razanne Habash, Ye-Jin Kang +3 more

    2022Frontiers in Rehabilitation Sciences18 citations Open access

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20. Comparator Groups in ICU-Based Studies of Physical Rehabilitation: A Scoping Review of 125 Studies

    H. O'Grady, J. Reid, Chris Farley, Quincy E. B. Hanna +5 more

    2023Critical Care Explorations16 citations Open access

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21. The Efficacy and Safety of in-ICU Leg Cycle Ergometry in Critically Ill Adults: A Systematic Review and Meta-Analysis.

    A. Takaoka, R. Utgikar, B. Rochwerg, D. Cook +1 more

    2020Annals of the American Thoracic Society16 citations

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22. From Strict Bedrest to Early Mobilization: A History of Physiotherapy in the Intensive Care Unit.

    M. Kho, B. Connolly

    2023Critical care clinics15 citations

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23. Executive Summary of a Focused Update to the Clinical Practice Guidelines for the Prevention and Management of Pain, Anxiety, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption in Adult Patients in the ICU.

    Kimberley Lewis, M. Balas, Joanna L. Stollings, Molly McNett +20 more

    2025Critical Care Medicine14 citations

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24. Effect of Enhanced Versus Usual Mobilization Activities in Critically Ill Adults: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

    K. Carayannopoulos, Dipayan Chaudhuri, Molly McNett, Michele C Balas +14 more

    2025Critical Care Medicine13 citations

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25. Post-Intensive Care Sequelae in Pediatrics—Results of an Early Rehabilitation Implementation Study

    K. Choong, Douglas D. Fraser, S. Cameron, Carlos A. Cuello +8 more

    2024Pediatric Critical Care Medicine13 citations

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26. Barriers, Solutions, and Opportunities for Adapting Critical Care Clinical Trials in the COVID-19 Pandemic

    Deborah Cook, Shipra Taneja, K. Krewulak, N. Zytaruk +27 more

    2024JAMA Network Open12 citations Open access

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27. Evidence-informed consensus statements to guide COVID-19 patient visitation policies: results from a national stakeholder meeting

    K. Fiest, Karla D. Krewulak, Laura Hernández, N. Jaworska +19 more

    2022Canadian Journal of Anesthesia/Journal canadien d'anesthésie12 citations Open access

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28. Leg Cycle Ergometry in Critically Ill Patients - An Updated Systematic Review and Meta-Analysis.

    H. O'Grady, Hibaa Hasan, B. Rochwerg, D. Cook +4 more

    2024NEJM Evidence11 citations

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29. A Modified Delphi Process to Prioritize Experiences and Guidance Related to ICU Restricted Visitation Policies During the Coronavirus Disease 2019 Pandemic

    K. Fiest, Karla D. Krewulak, Kira Makuk, N. Jaworska +17 more

    2021Critical Care Explorations11 citations Open access

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30. Barriers and Facilitators to Early Rehabilitation in the ICU: A Theory Driven Delphi Study.

    B. Cuthbertson, S. Goddard, F. Lorencatto, E. Koo +6 more

    2020Critical Care Medicine11 citations

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31. Post-COVID-19 condition symptoms among emergency department patients tested for SARS-CoV-2 infection

    P. Archambault, R. Rosychuk, M. Audet, J. Hau +42 more

    2024Nature Communications10 citations Open access

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32. A framework of research priorities in COVID rehabilitation from the Rehabilitation Science Research Network for COVID: an international consultation involving qualitative and quantitative research

    Kelly K. O'Brien, K. McDuff, Vijay Kumar Chattu, Katie Churchill +12 more

    2024Disability and Rehabilitation10 citations Open access

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33. To mobilise or not to mobilise: is that the right question?

    C. Hodgson, M. Kho, Vinicius Maldaner da Silva

    2023Intensive Care Medicine10 citations Open access

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34. Critical Care Cycling to Improve Lower Extremity Strength (CYCLE): protocol for an international, multicentre randomised clinical trial of early in-bed cycling for mechanically ventilated patients

    M. Kho, J. Reid, Alexander J. Molloy, M. Herridge +31 more

    2023BMJ Open9 citations Open access

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35. Adherence of Clinical Practice Guidelines for Pharmacologic Treatments of Hospitalized Patients With COVID-19 to Trustworthy Standards

    K. Burns, Matthew Laird, J. Stevenson, K. Honarmand +13 more

    2021JAMA Network Open9 citations Open access

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36. Evolution of practice patterns in the management of acute respiratory distress syndrome: A secondary analysis of two successive randomized controlled trials

    K. Tatham, N. Ferguson, Qi Zhou, L. Hand +11 more

    2021Journal of critical care9 citations Open access

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37. Society of Critical Care Medicine Guidelines on Caring for Older Adults in the ICU.

    L. Ferrante, Dipayan Chaudhuri, Kallirroi Laiya Carayannopoulos, Snigdha Jain +18 more

    2026Critical Care Medicine8 citations

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38. Cost-Effectiveness of In-Bed Cycling and Routine Physiotherapy for Patients Receiving Mechanical Ventilation

    J. Tarride, G. Blackhouse, B. Rochwerg, Alison E. Fox-Robichaud +26 more

    2025JAMA Network Open8 citations

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39. Treatment Fidelity in 94 Randomized Controlled Trials of Physical Rehabilitation in the ICU: A Scoping Review*

    Chris Farley, A. Newman, Jen Hoogenes, Dina Brooks +2 more

    2024Critical Care Medicine8 citations

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40. Research interrupted: applying the CONSERVE 2021 Statement to a randomized trial of rehabilitation during critical illness affected by the COVID-19 pandemic

    J. Reid, Alexander J. Molloy, G. Strong, L. Kelly +22 more

    2022Trials8 citations Open access

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41. CardiO Cycle: a pilot feasibility study of in-bed cycling in critically ill patients post cardiac surgery

    Anastasia N. L. Newman, M. Kho, J. Harris, N. Zamir +3 more

    2021Pilot and Feasibility Studies7 citations Open access

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42. Operationalization, measurement, and health indicators of sedentary behavior in individuals with cerebral palsy: a scoping review

    Julia Shi-Peng Xiong, S. Reedman, M. Kho, B. Timmons +2 more

    2021Disability and Rehabilitation7 citations

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43. Pilot and Feasibility Studies in Rehabilitation: Moving into the Next Decade.

    M. Kho, L. Thabane

    2020Physiotherapy Canada. Physiothérapie Canada7 citations Open access

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44. Standard of care for rehabilitation in critical illness

    Carol L. Hodgson, E. Ayre, Tessa Broadley, L. Burry +10 more

    2026Intensive Care Medicine6 citations Open access

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45. Cough Assessment and Management in Pulmonary Rehabilitation– A Canadian Survey

    A. Ilicic, D. Brooks, M. Kho, Roger S. Goldstein +1 more

    2023COPD6 citations Open access

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46. Rehabilitation needs, preferences, barriers, and facilitators of individuals with sepsis: a qualitative study

    J. Smith-Turchyn, Melina Alborzi, Julianne Hong, Jordon L Hvizd +4 more

    2025International Journal of Nursing Studies Advances5 citations Open access

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47. Co-designing and pilot testing an infographic to support patients/families through the REMAP-CAP consent process: a mixed-methods study protocol

    H. O'Grady, Zahra Bhimani, S. Dalziel, Barbara Dolanjski +6 more

    2023Pilot and Feasibility Studies5 citations Open access

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48. Critically appraised paper: In adults receiving intensive care, increased early active mobilisation did not improve clinical outcomes but increased adverse events [commentary].

    M. Kho

    2022Journal of Physiotherapy5 citations Open access

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49. The effect of COVID-19 on critical care research during the first year of the pandemic: A prospective longitudinal multinational survey

    M. Duffett, Deborah J. Cook, G. Strong, M. Binf +2 more

    20215 citations

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50. The response of Canada’s clinical health research ecosystem to the COVID-19 pandemic

    François Lamontagne, Marie-Hélène Masse, C. Yarnell, F. Camirand-Lemyre +19 more

    2024Canadian Medical Association Journal4 citations Open access

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