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H. Hisaeda · SciRah

Researcher profile · Semantic Scholar

H. Hisaeda

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H. Hisaeda — researcher profile on SciRah

h-index: 37
Works: 151
Citations: 4,801

Most-cited papers

Escape of malaria parasites from host immunity requires CD4+CD25+ regulatory T cells
H. Hisaeda, Y. Maekawa, Daiji Iwakawa, H. Okada +4 more
2004Nature Medicine426 citations
Semantic Scholar
WSX-1 is required for resistance to Trypanosoma cruzi infection by regulation of proinflammatory cytokine production.
S. Hamano, K. Himeno, Y. Miyazaki, Kazunari Ishii +7 more
2003Immunity307 citations Open access
Semantic Scholar
Pathological role of Toll-like receptor signaling in cerebral malaria.
C. Coban, K. Ishii, S. Uematsu, N. Arisue +7 more
2006International Immunology173 citations
Semantic Scholar
Mast Cells Are Crucial for Induction of Group 2 Innate Lymphoid Cells and Clearance of Helminth Infections
C. Shimokawa, T. Kanaya, Masami Hachisuka, K. Ishiwata +6 more
2017Immunity167 citations Open access
Semantic Scholar
Genetic variations of Toll-like receptor 9 predispose to systemic lupus erythematosus in Japanese population
Kayoko Tao, M. Fujii, S. Tsukumo, Y. Maekawa +7 more
2007Annals of the Rheumatic Diseases167 citations Open access
Semantic Scholar
Human Gut Microbiota and Its Metabolites Impact Immune Responses in COVID-19 and Its Complications
N. Nagata, T. Takeuchi, Hiroaki Masuoka, Ryo Aoki +23 more
2022Gastroenterology130 citations Open access
Semantic Scholar
Malaria: immune evasion by parasites.
H. Hisaeda, K. Yasutomo, K. Himeno
2005International Journal of Biochemistry and Cell Biology113 citations
Semantic Scholar
Plasmodium vivax parasites alter the balance of myeloid and plasmacytoid dendritic cells and induction of regulatory T cells
K. Jangpatarapongsa, P. Chootong, J. Sattabongkot, K. Chotivanich +6 more
2008European Journal of Immunology100 citations Open access
Semantic Scholar
Involvement of CD8+ T cells in protective immunity against murine blood‐stage infection with Plasmodium yoelii 17XL strain
T. Imai, Jian-Ying Shen, B. Chou, X. Duan +8 more
2010European Journal of Immunology99 citations
Semantic Scholar
Malaria Parasites Require TLR9 Signaling for Immune Evasion by Activating Regulatory T Cells1
H. Hisaeda, Kohhei Tetsutani, T. Imai, Chikako Moriya +14 more
2008Journal of Immunology99 citations Open access
Semantic Scholar
Plasmodium berghei ANKA causes intestinal malaria associated with dysbiosis
T. Taniguchi, E. Miyauchi, S. Nakamura, M. Hirai +13 more
2015Scientific Reports94 citations Open access
Semantic Scholar
Merozoite surface protein 3 and protection against malaria in Aotus nancymai monkeys.
H. Hisaeda, A. Saul, Joshua J. Reece, Michael C. Kennedy +3 more
2002Journal of Infectious Diseases89 citations Open access
Semantic Scholar
CD8+ regulatory T cells are critical in prevention of autoimmune-mediated diabetes
C. Shimokawa, Tamotsu Kato, T. Takeuchi, Noriyasu Ohshima +11 more
2020Nature Communications88 citations Open access
Semantic Scholar
Intestinal Intraepithelial Lymphocytes Sustain the Epithelial Barrier Function against Eimeria vermiformis Infection
K. Inagaki-Ohara, F. N. Dewi, H. Hisaeda, A. Smith +5 more
2006Infection and Immunity88 citations Open access
Semantic Scholar
TLR-Dependent Induction of IFN-β Mediates Host Defense against Trypanosoma cruzi1
R. Koga, S. Hamano, H. Kuwata, K. Atarashi +7 more
2006Journal of Immunology86 citations Open access
Semantic Scholar
A possible origin population of pathogenic intestinal nematodes, Strongyloides stercoralis, unveiled by molecular phylogeny
E. Nagayasu, Myo Pa Pa Thet Hnin Htwe Aung, Thanaporn Hortiwakul, Akina Hino +23 more
2017Scientific Reports76 citations Open access
Semantic Scholar
Cytotoxic activities of CD8+ T cells collaborate with macrophages to protect against blood-stage murine malaria
T. Imai, Hidekazu Ishida, K. Suzue, T. Taniguchi +3 more
2015eLife61 citations Open access
Semantic Scholar
Blocking of transmission to mosquitoes by antibody to Plasmodium vivax malaria vaccine candidates Pvs25 and Pvs28 despite antigenic polymorphism in field isolates.
J. Sattabongkot, T. Tsuboi, H. Hisaeda, M. Tachibana +7 more
2003American Journal of Tropical Medicine and Hygiene57 citations Open access
Semantic Scholar
Concurrent infection with Heligmosomoides polygyrus suppresses anti‐Plasmodium yoelii protection partially by induction of CD4+CD25+Foxp3+ Treg in mice
Kohhei Tetsutani, K. Ishiwata, Hidekazu Ishida, Liping Tu +4 more
2009European Journal of Immunology52 citations Open access
Semantic Scholar
IL-18 gene therapy develops Th1-type immune responses in Leishmania major-infected BALB/c mice: is the effect mediated by the CpG signaling TLR9?
Yang Li, Kazunari Ishii, H. Hisaeda, Shinjiro Hamano +8 more
2004Gene Therapy50 citations Open access
Semantic Scholar
A novel DNA vaccine based on ubiquitin–proteasome pathway targeting ‘self’-antigens expressed in melanoma/melanocyte
Man-Xin Zhang, Chikage Obata, H. Hisaeda, Kazunari Ishii +9 more
2005Gene Therapy47 citations Open access
Semantic Scholar
Toxoplasmosis encephalitis following severe graft‐vs.‐host disease after allogeneic hematopoietic stem cell transplantation: 17 yr experience in Fukuoka BMT group
Yayoi Matsuo, Shoichiro Takeishi, T. Miyamoto, A. Nonami +14 more
2007European Journal of Haematology44 citations
Semantic Scholar
Critical role for the immunoproteasome subunit LMP7 in the resistance of mice to Toxoplasma gondii infection
Liping Tu, Chikako Moriya, T. Imai, Hidekazu Ishida +7 more
2009European Journal of Immunology43 citations Open access
Semantic Scholar
Serum antibodies induced by intranasal immunization of mice with Plasmodium vivax Pvs25 co-administered with cholera toxin completely block parasite transmission to mosquitoes.
T. Arakawa, T. Tsuboi, Ayano Kishimoto, J. Sattabongkot +9 more
2003Vaccine43 citations
Semantic Scholar
Transient role of CD4+CD25+ regulatory T cells in mycobacterial infection in mice.
Y. Ozeki, I. Sugawara, T. Udagawa, T. Aoki +7 more
2010International Immunology42 citations Open access
Semantic Scholar
Roles of NKT cells in resistance against infection with Toxoplasma gondii and in expression of heat shock protein 65 in the host macrophages.
Yoko Nakano, H. Hisaeda, T. Sakai, H. Ishikawa +7 more
2002Microbes and infection42 citations Open access
Semantic Scholar
CD8+ T cell activation by murine erythroblasts infected with malaria parasites
T. Imai, Hidekazu Ishida, K. Suzue, M. Hirai +5 more
2013Scientific Reports39 citations Open access
Semantic Scholar
TLR-dependent induction of IFN-beta mediates host defense against Trypanosoma cruzi.
R. Koga, S. Hamano, H. Kuwata, K. Atarashi +7 more
2006Journal of Immunology39 citations
Semantic Scholar
Malaria parasite induces tryptophan-related immune suppression in mice
Kohhei Tetsutani, H. To, M. Torii, H. Hisaeda +1 more
2007Parasitology38 citations
Semantic Scholar
Development of experimental cerebral malaria is independent of IL-23 and IL-17.
Hidekazu Ishida, Chikako Matsuzaki-Moriya, T. Imai, K. Yanagisawa +8 more
2010Biochemical and Biophysical Research Communications - BBRC37 citations
Semantic Scholar
Cathepsin L is crucial for a Th1-type immune response during Leishmania major infection.
K. Onishi, Yang Li, Kazunari Ishii, H. Hisaeda +6 more
2004Microbes and infection37 citations Open access
Semantic Scholar
Treatment with cathepsin L inhibitor potentiates Th2-type immune response in Leishmania major-infected BALB/c mice.
Tian-Qiang Zhang, Y. Maekawa, T. Sakai, Yoko Nakano +6 more
2001International Immunology36 citations
Semantic Scholar
Queuine Is a Nutritional Regulator of Entamoeba histolytica Response to Oxidative Stress and a Virulence Attenuator
S. Nagaraja, Ma Cai, Jing-Jing Sun, Hugo Varet +14 more
2020mBio35 citations Open access
Semantic Scholar
IL‐23 protection against Plasmodium berghei infection in mice is partially dependent on IL‐17 from macrophages
Hidekazu Ishida, T. Imai, K. Suzue, M. Hirai +7 more
2013European Journal of Immunology35 citations Open access
Semantic Scholar
Escherichia coli mediated resistance of Entamoeba histolytica to oxidative stress is triggered by oxaloacetate
Yana Shaulov, C. Shimokawa, Meirav Trebicz‐Geffen, S. Nagaraja +6 more
2018PLoS Pathogens32 citations Open access
Semantic Scholar
Ubiquitin‐fusion degradation pathway plays an indispensable role in naked DNA vaccination with a chimeric gene encoding a syngeneic cytotoxic T lymphocyte epitope of melanocyte and green fluorescent protein
Man-Xin Zhang, Kazunari Ishii, H. Hisaeda, S. Murata +6 more
2004Immunology32 citations
Semantic Scholar
Antibodies to Plasmodium vivax transmission-blocking vaccine candidate antigens Pvs25 and Pvs28 do not show synergism.
H. Hisaeda, William E. Collins, A. Saul, A. Stowers
2001Vaccine32 citations
Semantic Scholar
A critical role for phagocytosis in resistance to malaria in iron‐deficient mice
Chikako Matsuzaki-Moriya, Liping Tu, Hidekazu Ishida, T. Imai +6 more
2011European Journal of Immunology31 citations Open access
Semantic Scholar
Resistance of regulatory T cells to glucocorticoid‐viduced TNFR family‐related protein (GITR) during Plasmodium yoelii infection
H. Hisaeda, S. Hamano, Chikage Mitoma-Obata, Kohhei Tetsutani +4 more
200531 citations
Semantic Scholar
Gene gun-based co-immunization of merozoite surface protein-1 cDNA with IL-12 expression plasmid confers protection against lethal Plasmodium yoelii in A/J mice.
T. Sakai, H. Hisaeda, Yoko Nakano, Man-Xin Zhang +8 more
2003Vaccine31 citations
Semantic Scholar
Suppression of Obesity by an Intestinal Helminth through Interactions with Intestinal Microbiota
C. Shimokawa, Seiji Obi, M. Shibata, A. Olia +3 more
2019Infection and Immunity29 citations Open access
Semantic Scholar
The involvement of immunoproteasomes in induction of MHC class I-restricted immunity targeting Toxoplasma SAG1.
Kazunari Ishii, H. Hisaeda, X. Duan, T. Imai +9 more
2006Microbes and infection26 citations Open access
Semantic Scholar
Antibodies specific for heat shock proteins in human and murine malaria.
Man-Xin Zhang, H. Hisaeda, Shigeyuki Kano, Y. Matsumoto +4 more
2001Microbes and infection25 citations Open access
Semantic Scholar
Efficient protective immunity against Trypanosoma cruzi infection after nasal vaccination with recombinant Sendai virus vector expressing amastigote surface protein-2.
X. Duan, Y. Yonemitsu, B. Chou, Kumi Yoshida +6 more
2009Vaccine24 citations
Semantic Scholar
Critical contribution of immunoproteasomes in the induction of protective immunity against Trypanosoma cruzi in mice vaccinated with a plasmid encoding a CTL epitope fused to green fluorescence protein.
B. Chou, H. Hisaeda, Jian-Ying Shen, X. Duan +5 more
2008Microbes and infection24 citations Open access
Semantic Scholar
Role of innate immune cells in protection against Toxoplasma gondii at inflamed site.
Yoko Nakano, H. Hisaeda, T. Sakai, Man-Xin Zhang +3 more
2001Journal of Medical Investigation24 citations
Semantic Scholar
Evaluating experimental cerebral malaria using oxidative stress indicator OKD48 mice.
T. Imai, T. Iwawaki, R. Akai, K. Suzue +4 more
2014International Journal of Parasitology23 citations
Semantic Scholar
The ubiquitin-proteasome system plays essential roles in presenting an 8-mer CTL epitope expressed in APC to corresponding CD8+ T cells.
X. Duan, H. Hisaeda, Jian-Ying Shen, Liping Tu +9 more
2006International Immunology20 citations Open access
Semantic Scholar
Three-dimensional electron microscopy analysis reveals endopolygeny-like nuclear architecture segregation in Plasmodium oocyst development.
Tamasa Araki, S. Kawai, Souichiro Kakuta, Hirotaka Kobayashi +10 more
2019Parasitology international19 citations Open access
Semantic Scholar
Malaria parasite evades mosquito immunity by glutaminyl cyclase–mediated posttranslational protein modification
S. K. Kolli, Alvaro Molina-Cruz, Tamasa Araki, Fiona J. A. Geurten +19 more
2022Proceedings of the National Academy of Sciences of the United States of America17 citations Open access
Semantic Scholar

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K. Himeno×20
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K. Himeno — researcher profile on SciRah
T. Imai×17
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T. Imai — researcher profile on SciRah
C. Shimokawa×14
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C. Shimokawa — researcher profile on SciRah
S. Hamano×10
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S. Hamano — researcher profile on SciRah

Hidekazu Ishida

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Hidekazu Ishida — researcher profile on SciRah

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X. Duan — researcher profile on SciRah

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K. Suzue — researcher profile on SciRah

Kazunari Ishii×8

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Kazunari Ishii — researcher profile on SciRah

Man-Xin Zhang×8

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Man-Xin Zhang — researcher profile on SciRah

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Liping Tu — researcher profile on SciRah

Kohhei Tetsutani×8

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Kohhei Tetsutani — researcher profile on SciRah

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Y. Maekawa — researcher profile on SciRah