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O. Elekofehinti · SciRah

Researcher profile · Semantic Scholar

O. Elekofehinti

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O. Elekofehinti — researcher profile on SciRah

h-index: 24
Works: 111
Citations: 1,613

Most-cited papers

Saponins: Anti-diabetic principles from medicinal plants - A review.
O. Elekofehinti
2015Pathophysiology166 citations Open access
Semantic Scholar
Computer-aided drug design in anti-cancer drug discovery: What have we learnt and what is the way forward? ?
Iwaloye Opeyemi, Olamide Paul, Femi Olawale, B. Olorunfemi +10 more
2023Informatics in Medicine Unlocked76 citations Open access
Semantic Scholar
Possible anti-diabetic potentials of Annona muricata (soursop): inhibition of α-amylase and α-glucosidase activities
K. C. Agu, N. Eluehike, Reuben Oseikhumen Ofeimun, Deborah Abile +4 more
2019Clinical Phytoscience63 citations Open access
Semantic Scholar
In silico molecular studies of natural compounds as possible anti-Alzheimer’s agents: ligand-based design
O. Iwaloye, O. Elekofehinti, Abiola Ibrahim Momoh, Kikiowo Babatomiwa +1 more
2020Network Modeling Analysis in Health Informatics and Bioinformatics46 citations
Semantic Scholar
Cytotoxic and antioxidative potentials of ethanolic extract of Eugenia uniflora L. (Myrtaceae) leaves on human blood cells.
Francisco Assis Bezerra da Cunha, E. Waczuk, A. Duarte, L. Barros +11 more
2016Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie44 citations
Semantic Scholar
Potential use of bitter melon (Momordica charantia) derived compounds as antidiabetics: In silico and in vivo studies.
O. Elekofehinti, Esther Ariyo, M. O. Akinjiyan, O. S. Olayeriju +3 more
2018Pathophysiology43 citations Open access
Semantic Scholar
Insight into glycogen synthase kinase-3β inhibitory activity of phyto-constituents from Melissa officinalis: in silico studies
O. Iwaloye, O. Elekofehinti, E. Oluwarotimi, Babatomiwa Kikiowo +1 more
2020In Silico Pharmacology42 citations Open access
Semantic Scholar
Discovery of potential visfatin activators using in silico docking and ADME predictions as therapy for type 2 diabetes
O. Elekofehinti, O. C. Ejelonu, J. Kamdem, Oluwaseun Benedicta Akinlosotu +6 more
2018Beni-Suef University Journal of Basic and Applied Sciences38 citations Open access
Semantic Scholar
Cymbopogon citratus (DC.) Stapf mitigates ER-stress induced by streptozotocin in rats via down-regulation of GRP78 and up-regulation of Nrf2 signaling.
O. Elekofehinti, A. Onunkun, T. Olaleye
2020Journal of Ethnopharmacology37 citations
Semantic Scholar
Involvement of fat mass and obesity gene (FTO) in the anti-obesity action of Annona muricata Annonaceae: in silico and in vivo studies
O. Elekofehinti, A. Lawal, O. C. Ejelonu, O. Molehin +1 more
2020Journal of Diabetes and Metabolic Disorders36 citations Open access
Semantic Scholar
The cardiovascular protective effects of rooibos (Aspalathus linearis) extract on diesel exhaust particles induced inflammation and oxidative stress involve NF-κB- and Nrf2-dependent pathways modulation
A. Lawal, Dare M. Oluyede, Monsurat O. Adebimpe, Lateefat T. Olumegbon +3 more
2019Heliyon36 citations Open access
Semantic Scholar
Tithonia diversifolia saponin-blood lipid interaction and its influence on immune system of normal wistar rats.
O. C. Ejelonu, O. Elekofehinti, I. G. Adanlawo
2017Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie30 citations
Semantic Scholar
Discovery of traditional Chinese medicine derived compounds as wild type and mutant Plasmodium falciparum dihydrofolate reductase inhibitors: Induced fit docking and ADME studies.
O. Iwaloye, O. Elekofehinti, Babatomiwa Kikiowo, T. M. Fadipe +4 more
2020Current Drug Discovery Technologies29 citations
Semantic Scholar
Caffeine-supplemented diet modulates oxidative stress markers and improves locomotor behavior in the lobster cockroach Nauphoeta cinerea.
C. S. da Silva, Rita de Cássia Gonçalves de Lima, O. Elekofehinti, Y. Ogunbolude +7 more
2018Chemico-Biological Interactions29 citations Open access
Semantic Scholar
Molecular docking and pharmacokinetic studies of phytocompounds from Nigerian Medicinal Plants as promising inhibitory agents against SARS-CoV-2 methyltransferase (nsp16)
T. Saliu, H. I. Umar, O. Ogunsile, M. Okpara +2 more
2021Journal of Genetic Engineering and Biotechnology28 citations Open access
Semantic Scholar
Possible involvement of transcriptional activation of nuclear factor erythroid 2-related factor 2 (Nrf2) in the protective effect of caffeic acid on paraquat-induced oxidative damage in Drosophila melanogaster.
Ricardo Gomes dos Santos Nunes, P. S. Pereira, O. Elekofehinti, K. Fidelis +9 more
2019Pesticide Biochemistry and Physiology28 citations
Semantic Scholar
Effects of Tapinanthus globiferus and Zanthoxylum zanthoxyloides extracts on human leukocytes in vitro
Y. Ogunbolude, M. Ibrahim, O. Elekofehinti, A. Adeniran +3 more
2014Journal of Intercultural Ethnopharmacology28 citations Open access
Semantic Scholar
Hesperetin protects against diesel exhaust particles-induced cardiovascular oxidative stress and inflammation in Wistar rats
Lateefat T. Olumegbon, A. Lawal, Dare M. Oluyede, Monsurat O. Adebimpe +2 more
2022Environmental science and pollution research international25 citations
Semantic Scholar
Saponins as adipokines modulator: A possible therapeutic intervention for type 2 diabetes
O. Elekofehinti, O. C. Ejelonu, J. Kamdem, Oluwaseun Benedicta Akinlosotu +1 more
2017World Journal of Diabetes24 citations Open access
Semantic Scholar
Virtual screening of natural compounds as selective inhibitors of polo-like kinase-1 at C-terminal polo box and N-terminal catalytic domain
Femi Olawale, O. Iwaloye, O. Elekofehinti
2021Journal of Biomolecular Structure and Dynamics21 citations
Semantic Scholar
Identification of Main Protease of Coronavirus SARS-CoV-2 (Mpro)Inhibitors from Melissa officinalis.
O. Elekofehinti, O. Iwaloye, C. D. Famusiwa, O. Akinseye +1 more
2020Current Drug Discovery Technologies19 citations
Semantic Scholar
Identification of lead compounds from large natural product library targeting 3C-like protease of SARS-CoV-2 using E-pharmacophore modelling, QSAR and molecular dynamics simulation
O. Elekofehinti, O. Iwaloye, O. Molehin, C. D. Famusiwa
2021In Silico Pharmacology16 citations Open access
Semantic Scholar
Comparative research performance of top universities from the northeastern Brazil on three pharmacological disciplines as seen in scopus database
J. Kamdem, K. Fidelis, R. Nunes, I. F. Araújo +6 more
2017Journal of Taibah University Medical Sciences15 citations Open access
Semantic Scholar
Screening of Compounds from Nigerian Antidiabetic Plants as Protein Tyrosine Phosphatase 1B Inhibitor
Femi Olawale, Kolawole Olofinsan, O. Iwaloye, P. Chukwuemeka +1 more
2021Computational Toxicology14 citations
Semantic Scholar
In silico Molecular Studies of Selected Compounds as Novel Inhibitors for Phosphodiesterase-5 (PDE5) in the Management of Erectile Dysfunction
O. Iwaloye, O. Elekofehinti, Kikiowo Babatomiwa, T. M. Fadipe
202014 citations
Semantic Scholar
Experimental and computational modeling of interaction of kolaviron-kolaflavanone with aldehyde dehydrogenase.
Adejoke N. Kolawole, Valentine T Akinladejo, O. Elekofehinti, A. Akinmoladun +1 more
2018Bioorganic chemistry (Print)14 citations
Semantic Scholar
Effect of Chrysophyllum albidum fruit pulp powder on antioxidant and proinflammatory genes in non-diabetic and type 2 diabetic rats
F. L. Oyetayo, S. Akomolafe, F. Jegede, O. Elekofehinti +2 more
2021Journal of Diabetes and Metabolic Disorders13 citations Open access
Semantic Scholar
Effects of Momordica Charantia Silver Nanoparticles on the expressions of Genes Associated With Lipid Metabolism and Nephrotoxicity in Streptozotocin-Induced Rats
O. Elekofehinti, M. O. Akinjiyan
202113 citations Open access
Semantic Scholar
Kolaflavanone of kolaviron selectively binds to subdomain 1B of human serum albumin: spectroscopic and molecular docking evidences
A. O. Kolawole, Adejoke N. Kolawole, K. Olofinsan, O. Elekofehinti
202012 citations
Semantic Scholar
Discovery of potential epidermal growth factor receptor inhibitors from black pepper for the treatment of lung cancer: an in-silico approach
O. Elekofehinti, I. Adetoyi, H. O. Popoola, F. O. Ayodeji +5 more
2024In Silico Pharmacology11 citations Open access
Semantic Scholar
Newly designed compounds from scaffolds of known actives as inhibitors of survivin: computational analysis from the perspective of fragment-based drug design
O. Elekofehinti, O. Iwaloye, Femi Olawale, P. Chukwuemeka +1 more
2021In Silico Pharmacology11 citations Open access
Semantic Scholar
Ascorbic Acid and Alpha-Tocopherol Contribute to the Therapy of Polycystic Ovarian Syndrome in Mouse Models
E. Bafor, A. Uchendu, O. Osayande, O. Omoruyi +5 more
2020Reproductive Sciences11 citations
Semantic Scholar
Exploring the antidiabetic potential of compounds isolated from Anacardium occidentale using computational aproach: ligand-based virtual screening
V. Ukwenya, S. Adelakun, O. Elekofehinti
2021In Silico Pharmacology10 citations Open access
Semantic Scholar
Effect of moonseed vine (Triclisia gilletii Staner) on ethane-1,2-diol-induced urolithiasis and its renotoxicity in Wistar albino rats
O. S. Olayeriju, O. Crown, O. Elekofehinti, A. Akinmoladun +2 more
2020African Journal of Urology10 citations Open access
Semantic Scholar
Isolation and Elucidation of 15-Acetylguanacone from Soursop ( Annona muricata Linn) Fruit and Molecular Docking Experiments
K. Agu, N. Okolie, A. Falodun, O. Erharuyi +4 more
201710 citations Open access
Semantic Scholar
The Antioxidative, Anti-inflammatory and Anti-apoptotic Effects of Tetrapleura Tetraptera (Aidan) Ethanol Leaf Extract in the Brain of Wistar Rats Exposed to Aspartame
A. Lawal, O. O. Agboola, M. O. Akinjiyan, T. T. Ijatuyi +5 more
2025Molecular Neurobiology8 citations
Semantic Scholar
Effects of Bryophyllum pinnatum on Dysfunctional Autophagy in Rats Lungs Exposed to Zinc Oxide Nanoparticles.
T. T. Ijatuyi, A. Lawal, M. O. Akinjiyan, F. M. Ojo +5 more
2024International Immunopharmacology8 citations
Semantic Scholar
Biochemical and molecular effects of naringenin on the cardiovascular oxidative and pro-inflammatory effects of oral exposure to diesel exhaust particles in rats
Dare M. Oluyede, A. Lawal, Monsurat O. Adebimpe, Lateefat T. Olumegbon +1 more
2021Air quality, atmosphere and health8 citations
Semantic Scholar
Machine Learning-based Virtual Screening Strategy Reveals Some Natural Compounds As Potential PAK4 Inhibitors In Triple Negative Breast Cancer
O. Iwaloye, O. Elekofehinti, Babatomiwa Kikiowo, E. Oluwarotimi +1 more
2020Current Protoemics8 citations
Semantic Scholar
Improvement of mitochondrial function by Tapinanthus globifer (A.Rich.) Tiegh. Against hepatotoxic agent in isolated rat's liver mitochondria.
O. Elekofehinti, J. Kamdem, T. Saliu, C. D. Famusiwa +2 more
2019Journal of Ethnopharmacology8 citations
Semantic Scholar
Investigation of Aframomum melegueta compounds as ERK5 inhibitor related to breast cancer via molecular docking and dynamic simulation
Paul Olamide Ottu, Olorunfemi Oyewole Babalola, Cecilia Oluwamodupe, Ayodeji Folasade Oluwatobiloba +4 more
2025In Silico Pharmacology7 citations
Semantic Scholar
In silico molecular studies of natural compounds as possible anti-Alzheimer’s agents: ligand-based design
O. Iwaloye, O. Elekofehinti, Abiola Ibrahim Momoh, Kikiowo Babatomiwa +1 more
2020Network Modeling Analysis in Health Informatics and Bioinformatics7 citations
Semantic Scholar
Saponin from the fruit of Solanum anguivi protects against oxidative damage mediated by Fe2+ and sodium nitroprusside in rat brain synaptosome P2 fraction
O. Elekofehinti, J. Kamdem, D. Meinerz, I. Kade +2 more
2015Archives of pharmacal research7 citations
Semantic Scholar
Evaluation of the protective effects of raw and roasted pumpkin (Cucurbita pepo L.) seed-supplemented diets on cisplatin-induced cardiotoxicity in rats
S. Akomolafe, M. O. Akinjiyan, N. Asogwa, O. Elekofehinti
2025Journal of Molecular Histology6 citations
Semantic Scholar
Bambusa vulgaris leaves reverse mitochondria dysfunction in diabetic rats through modulation of mitochondria biogenic genes
O. Elekofehinti, Y. V. Aladenika, O. Iwaloye, Enoabasi Ima-abasi Okon +1 more
2023Hormone Molecular Biology and Clinical Investigation6 citations
Semantic Scholar
Identification of Novel Nrf2 Activator via Protein-ligand Interactions as Remedy for Oxidative Stress in Diabetes Mellitus
A. Onunkun, O. Iwaloye, O. Elekofehinti
20216 citations
Semantic Scholar
The inhibitory effects of Centella asiatica compounds on myeloid cell leukemia 1 (MCL-1) in cancer: a computational study
Cecilia Oluwamodupe, Olorunfemi Oyewole Babalola, Paul Olamide Ottu, Erinayo Tolulope Aladeteloye +4 more
2025In Silico Pharmacology5 citations Open access
Semantic Scholar
Molecular modeling, dynamics simulation and characterization of human inositol hexakisphosphate kinase 1 (IP6K1) related to diabetes
O. Elekofehinti, Y. V. Aladenika, Y. R. Allismith, O. C. Ejelonu +1 more
2019Journal of Applied Sciences and Environmental Management5 citations Open access
Semantic Scholar
Cinnamic acid abrogates bisphenol A-induced hepatotoxicity via suppression of pro-inflammatory cytokine and modulation of gene expressions of antioxidant enzymes in rats
A. Adeyanju, E. Akinwunmi, M. Karigidi, O. Agboola +1 more
2025Toxicology Reports4 citations Open access
Semantic Scholar
Effects of 2,4-dichlorophenol on non–specific immunity, histopathological lesions, and redox balance in African Catfish, clarias gariepinus (Burchell, 1822)
O. Imade, Bobola V Ilesanmi, Germaine O Ogunwole, O. Elekofehinti +4 more
2024Journal of Toxicology and Environmental Health, Part A4 citations
Semantic Scholar

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M. O. Akinjiyan×9
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