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J. Seddon · SciRah

Researcher profile · Semantic Scholar

J. Seddon

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J. Seddon — researcher profile on SciRah

h-index: 93
Works: 295
Citations: 34K

Most-cited papers

Seven New Loci Associated with Age-Related Macular Degeneration
Lars G. Fritsche, Wei Chen, M. Schu, B. Yaspan +152 more
2013Nature Genetics800 citations Open access
Semantic Scholar
Rare variants in CFI, C3 and C9 are associated with high risk of advanced age-related macular degeneration
J. Seddon, Yi Yu, Elizabeth C. Miller, Robyn C. Reynolds +12 more
2013Nature Genetics362 citations Open access
Semantic Scholar
Blue Light Exposure: Ocular Hazards and Prevention—A Narrative Review
A. Cougnard-Grégoire, B. Merle, T. Aslam, J. Seddon +7 more
2023Ophthalmology and Therapy181 citations Open access
Semantic Scholar
Nature and nurture- genes and environment- predict onset and progression of macular degeneration
L. Sobrin, J. Seddon
2013Progress in retinal and eye research179 citations Open access
Semantic Scholar
Adherence to a Mediterranean diet, genetic susceptibility, and progression to advanced macular degeneration: a prospective cohort study.
B. Merle, Rachel E. Silver, B. Rosner, J. Seddon
2015American Journal of Clinical Nutrition141 citations Open access
Semantic Scholar
Genetic Variants in the Complement System Predisposing to Age-Related Macular Degeneration: A Review
Elizabeth C. Schramm, Simon J. Clark, M. Triebwasser, S. Raychaudhuri +2 more
2014Molecular Immunology122 citations Open access
Semantic Scholar
Prospective assessment of genetic effects on progression to different stages of age-related macular degeneration using multistate Markov models.
Yi Yu, Robyn C. Reynolds, B. Rosner, M. Daly +1 more
2012Investigative Ophthalmology and Visual Science122 citations Open access
Semantic Scholar
Rare genetic variants in the CFI gene are associated with advanced age-related macular degeneration and commonly result in reduced serum factor I levels
D. Kavanagh, Yi Yu, Elizabeth C. Schramm, M. Triebwasser +5 more
2015Human Molecular Genetics117 citations Open access
Semantic Scholar
Variation of second cancer risk by family history of retinoblastoma among long-term survivors.
R. Kleinerman, Chu-Ling Yu, M. Little, Yi Li +3 more
2012Journal of Clinical Oncology112 citations Open access
Semantic Scholar
Risk of subsequent malignant neoplasms in long-term hereditary retinoblastoma survivors after chemotherapy and radiotherapy.
Jeannette R. Wong, L. Morton, M. Tucker, D. Abramson +3 more
2014Journal of Clinical Oncology111 citations Open access
Semantic Scholar
Optical Coherence Tomography Features Preceding the Onset of Advanced Age-Related Macular Degeneration
D. Ferrara, Rachel E. Silver, R. Louzada, E. Novais +2 more
2017Investigative Ophthalmology and Visual Science108 citations Open access
Semantic Scholar
Risk Prediction for Progression of Macular Degeneration: 10 Common and Rare Genetic Variants, Demographic, Environmental, and Macular Covariates.
J. Seddon, Rachel E. Silver, Manlik Kwong, B. Rosner
2015Investigative Ophthalmology and Visual Science106 citations Open access
Semantic Scholar
Whole-exome sequencing identifies rare, functional CFH variants in families with macular degeneration.
Yi Yu, M. Triebwasser, E. Wong, Elizabeth C. Schramm +8 more
2014Human Molecular Genetics106 citations Open access
Semantic Scholar
Increased choroidal mast cells and their degranulation in age-related macular degeneration
I. Bhutto, D. Mcleod, Tian Jing, J. Sunness +2 more
2016British Journal of Ophthalmology85 citations Open access
Semantic Scholar
Heritability and Genome-wide Association Study To Assess Genetic Differences Between Advanced Age-Related Macular Degeneration Subtypes
L. Sobrin, S. Ripke, Yi Yu, J. Fagerness +30 more
2012Ophthalmology (Rochester, Minn.)85 citations Open access
Semantic Scholar
Dietary Omega-3 Fatty Acids, Other Fat Intake, Genetic Susceptibility and Progression to Incident Geographic Atrophy
Robyn C. Reynolds, B. Rosner, J. Seddon
2013Ophthalmology (Rochester, Minn.)84 citations Open access
Semantic Scholar
Macular Degeneration Epidemiology: Nature-Nurture, Lifestyle Factors, Genetic Risk, and Gene-Environment Interactions – The Weisenfeld Award Lecture
J. Seddon
2017Investigative Ophthalmology and Visual Science73 citations Open access
Semantic Scholar
The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: a HuGE review and meta-analysis.
A. Thakkinstian, M. McEvoy, U. Chakravarthy, Subhabrata Chakrabarti +11 more
2012American Journal of Epidemiology69 citations Open access
Semantic Scholar
Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration.
M. Triebwasser, Elisha D. O. Roberson, Yi Yu, Elizabeth C. Schramm +4 more
2015Investigative Ophthalmology and Visual Science68 citations Open access
Semantic Scholar
Genetic factors for choroidal neovascularization associated with high myopia.
N. Leveziel, Yi Yu, Robyn C. Reynolds, A. Tai +7 more
2012Investigative Ophthalmology and Visual Science64 citations Open access
Semantic Scholar
Ophthalmology 1 Age-related macular degeneration
L. Lim, P. Mitchell, J. Seddon, F. Holz +1 more
201263 citations
Semantic Scholar
Vitamin D and Age-Related Macular Degeneration
A. Layana, A. Minnella, G. Garhöfer, T. Aslam +6 more
2017Nutrients59 citations Open access
Semantic Scholar
Three New Genetic Loci (R1210C in CFH, Variants in COL8A1 and RAD51B) Are Independently Related to Progression to Advanced Macular Degeneration
J. Seddon, Robyn C. Reynolds, Yi Yu, B. Rosner
2014PLoS ONE59 citations Open access
Semantic Scholar
Deep Ensemble Learning for Automated Non-advanced AMD Classification Using Optimized Retinal Layer Segmentation and SD-OCT Scans
Mousa Moradi, Yu Chen, Xian Du, J. Seddon
2023Comput. Biol. Medicine57 citations Open access
Semantic Scholar
Associations Between Vitamin D Intake and Progression to Incident Advanced Age-Related Macular Degeneration
B. Merle, Rachel E. Silver, B. Rosner, J. Seddon
2017Investigative Ophthalmology and Visual Science54 citations Open access
Semantic Scholar
Response to AREDS Supplements According to Genetic Factors: Survival Analysis Approach Using the Eye as the Unit of Analysis
J. Seddon, Rachel E. Silver, B. Rosner
2016British Journal of Ophthalmology54 citations Open access
Semantic Scholar
Dietary folate, B vitamins, genetic susceptibility and progression to advanced nonexudative age-related macular degeneration with geographic atrophy: a prospective cohort study.
B. Merle, Rachel E. Silver, B. Rosner, J. Seddon
2016American Journal of Clinical Nutrition53 citations Open access
Semantic Scholar
Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden, and lower antigenic levels in familial AMD
Erin K. Wagner, S. Raychaudhuri, M. Villalonga, A. Java +4 more
2016Scientific Reports52 citations Open access
Semantic Scholar
Validation of a Prediction Algorithm for Progression to Advanced Macular Degeneration Subtypes
J. Seddon, Robyn C. Reynolds, Yi Yu, B. Rosner
2013JAMA ophthalmology51 citations Open access
Semantic Scholar
Phenotypic Characterization of Complement Factor H R1210C Rare Genetic Variant in Age-Related Macular Degeneration
D. Ferrara, J. Seddon
2015JAMA ophthalmology45 citations Open access
Semantic Scholar
Predictors of Response to Intravitreal Anti-Vascular Endothelial Growth Factor Treatment of Age-Related Macular Degeneration
Anjali R. Shah, Steven L. Williams, C. Baumal, B. Rosner +2 more
2015American journal of ophthalmology-glaucoma44 citations Open access
Semantic Scholar
Validated Prediction Models for Macular Degeneration Progression and Predictors of Visual Acuity Loss Identify High Risk Individuals
J. Seddon, B. Rosner
2018American journal of ophthalmology-glaucoma43 citations Open access
Semantic Scholar
Genetic and environmental underpinnings to age-related ocular diseases.
J. Seddon
2013Investigative Ophthalmology and Visual Science43 citations Open access
Semantic Scholar
Allele-Specific Methylation Occurs at Genetic Variants Associated with Complex Disease
John N. Hutchinson, T. Raj, J. Fagerness, E. Stahl +6 more
2014PLoS ONE41 citations Open access
Semantic Scholar
Long-term risk of subsequent cancer incidence among hereditary and nonhereditary retinoblastoma survivors
S. Schonfeld, R. Kleinerman, D. Abramson, J. Seddon +2 more
2021British Journal of Cancer33 citations Open access
Semantic Scholar
Rare and Common Genetic Variants, Smoking, and Body Mass Index: Progression and Earlier Age of Developing Advanced Age-Related Macular Degeneration
J. Seddon, R. Widjajahakim, B. Rosner
2020Investigative Ophthalmology and Visual Science33 citations Open access
Semantic Scholar
Functional Analysis of Rare Genetic Variants in Complement Factor I (CFI) using a Serum-Based Assay in Advanced Age-related Macular Degeneration
A. Java, P. Baciu, R. Widjajahakim, Yun J. Sung +4 more
2020Translational Vision Science & Technology32 citations Open access
Semantic Scholar
Contribution of the Nurses' Health Study to the Epidemiology of Cataract, Age-Related Macular Degeneration, and Glaucoma.
J. Kang, Juan Wu, E. Cho, S. Ogata +8 more
2016American Journal of Public Health31 citations Open access
Semantic Scholar
Genetic Susceptibility, Diet Quality, and Two-Step Progression in Drusen Size
B. Merle, B. Rosner, J. Seddon
2020Investigative Ophthalmology and Visual Science30 citations Open access
Semantic Scholar
Patterns of Cause-Specific Mortality Among 2053 Survivors of Retinoblastoma, 1914-2016.
R. Kleinerman, M. Tucker, Byron S Sigel, D. Abramson +2 more
2019Journal of the National Cancer Institute29 citations Open access
Semantic Scholar
Bone and Soft‐Tissue Sarcoma Risk in Long‐Term Survivors of Hereditary Retinoblastoma Treated With Radiation
R. Kleinerman, S. Schonfeld, Byron S Sigel, Jeannette R. Wong-Siegel +5 more
2019Journal of Clinical Oncology24 citations Open access
Semantic Scholar
Protective coding variants in CFH and PELI3 and a variant near CTRB1 are associated with age-related macular degeneration
Erin K. Wagner, Yi Yu, E. Souied, S. Seitsonen +5 more
2015bioRxiv23 citations Open access
Semantic Scholar
Breast cancer risk after radiotherapy for heritable and non-heritable retinoblastoma: a US–UK study
M. Little, M. Schaeffer, R. Reulen, D. Abramson +8 more
2014British Journal of Cancer20 citations Open access
Semantic Scholar
Association Between Perifoveal Drusen Burden Determined by OCT and Genetic Risk in Early and Intermediate Age-Related Macular Degeneration
J. Seddon, James Dossett, R. Widjajahakim, B. Rosner
2019Investigative Ophthalmology and Visual Science16 citations Open access
Semantic Scholar
Analysis of Choroidal and Retinal Vasculature in Inherited Retinal Degenerations Using Optical Coherence Tomography Angiography
Talisa E. de Carlo, M. Adhi, D. Salz, Tony Joseph +4 more
2016Ophthalmic Surgery Lasers and Imaging Retina16 citations Open access
Semantic Scholar
(Epi)Genetic Analyses of Age-Related Macular Degeneration: Case-control and Discordant Twin Studies
John N. Hutchinson, J. Fagerness, Andrew W. Kirby, Robyn C. Reynolds +6 more
2014Human Heredity16 citations Open access
Semantic Scholar
The rare C9 P167S risk variant for age-related macular degeneration increases polymerization of the terminal component of the complement cascade
O. McMahon, T. Hallam, S. Patel, C. Harris +19 more
2021Human Molecular Genetics15 citations Open access
Semantic Scholar
Automated discovery and quantification of image-based complex phenotypes: a twin study of drusen phenotypes in age-related macular degeneration.
G. Quellec, S. Russell, J. Seddon, Robyn C. Reynolds +4 more
2011Investigative Ophthalmology and Visual Science15 citations Open access
Semantic Scholar
The Redox Couple Between Glutathione and Ascorbic Acid : A Chemical and Physiological Perspective ”
H. M. Hittner, J. Seddon
201714 citations
Semantic Scholar
Rare Dysfunctional Complement Factor I Genetic Variants and Progression to Advanced Age-Related Macular Degeneration
J. Seddon, Bernard A. Rosner, Dikha De, T. Huan +2 more
2022medRxiv10 citations Open access
Semantic Scholar

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