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J. Decano · SciRah

Researcher profile · Semantic Scholar

J. Decano

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J. Decano — researcher profile on SciRah

h-index: 15
Works: 53
Citations: 764

Most-cited papers

Uremic toxin indoxyl sulfate promotes pro-inflammatory macrophage activation via the interplay of OATP2B1 and Dll4-Notch signaling
T. Nakano, Shunsuke Katsuki, Mingxiang Chen, J. Decano +20 more
2019Circulation179 citations Open access
Semantic Scholar
Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms
Shunsuke Katsuki, P. Jha, Adrien Lupieri, T. Nakano +20 more
2022Circulation Research65 citations Open access
Semantic Scholar
Macrophage Notch ligand Delta-like 4 promotes vein graft lesion development: implications for the treatment of vein graft failure
Jun-ichiro Koga, T. Nakano, J. Dahlman, J. Figueiredo +10 more
2015Arteriosclerosis, Thrombosis and Vascular Biology52 citations Open access
Semantic Scholar
A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profiling.
J. Decano, Yukio Iwamoto, S. Goto, Jane Lee +17 more
2022Cell Reports42 citations Open access
Semantic Scholar
Macrophages in Vascular Inflammation: Origins and Functions
J. Decano, Peter C. Mattson, M. Aikawa
2016Current Atherosclerosis Reports41 citations
Semantic Scholar
Association of ATP1A1 and Dear Single-Nucleotide Polymorphism Haplotypes With Essential Hypertension: Sex-Specific and Haplotype-Specific Effects
N. Glorioso, V. Herrera, P. Bagamasbad, F. Filigheddu +5 more
2007Circulation Research41 citations Open access
Semantic Scholar
Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease
J. Decano, Sasha A. Singh, Cauê Gasparotto Bueno, Lang H. Lee +14 more
2021Circulation30 citations Open access
Semantic Scholar
Prestroke Proteomic Changes in Cerebral Microvessels in Stroke-Prone, Transgenic[hCETP]-Hyperlipidemic, Dahl Salt-Sensitive Hypertensive Rats
A. Bergerat, J. Decano, Chang-Jiun Wu, Hyungwon Choi +5 more
2011Molecular Medicine30 citations Open access
Semantic Scholar
Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes
Amitabh Sharma, A. Halu, J. Decano, M. Padi +12 more
2017npj Systems Biology and Applications27 citations Open access
Semantic Scholar
Aortic and Carotid Arterial Stiffness and Epigenetic Regulator Gene Expression Changes Precede Blood Pressure Rise in Stroke-Prone Dahl Salt-Sensitive Hypertensive Rats
V. Herrera, J. Decano, Nicholas J. Giordano, A. Moran +1 more
2014PLoS ONE27 citations Open access
Semantic Scholar
Dynamic Macrophages: Understanding Mechanisms of Activation as Guide to Therapy for Atherosclerotic Vascular Disease
J. Decano, M. Aikawa
2018Frontiers in Cardiovascular Medicine25 citations Open access
Semantic Scholar
Cellular Heterogeneity of Activated Primary Human Macrophages and Associated Drug–Gene Networks: From Biology to Precision Therapeutics
J. Decano, E. Maiorino, J. Matamalas, S. Chelvanambi +14 more
2023Circulation23 citations Open access
Semantic Scholar
DEspR Roles in Tumor Vasculo-Angiogenesis, Invasiveness, CSC-Survival and Anoikis Resistance: A ‘Common Receptor Coordinator’ Paradigm
V. Herrera, J. Decano, Glaiza L. A. Tan, A. Moran +3 more
2014PLoS ONE21 citations Open access
Semantic Scholar
Molecular Imaging of Vasa Vasorum Neovascularization via DEspR-targeted Contrast-enhanced Ultrasound Micro-imaging in Transgenic Atherosclerosis Rat Model
J. Decano, A. Moran, N. Ruiz‐Opazo, V. Herrera
2011Molecular Imaging and Biology20 citations Open access
Semantic Scholar
Early-life Sodium-exposure Unmasks Susceptibility to Stroke in hyperlipidemic-hypertensive Tg[hCETP]25-Rats
J. Decano, J. Viereck, A. Mckee, J. Hamilton +2 more
2009Circulation19 citations Open access
Semantic Scholar
In silico Drug Screening Approach Using L1000-Based Connectivity Map and Its Application to COVID-19
Takaharu Asano, S. Chelvanambi, J. Decano, M. Whelan +2 more
2022Frontiers in Cardiovascular Medicine15 citations Open access
Semantic Scholar
Sex-specific hippocampus-dependent cognitive deficits and increased neuronal autophagy in DEspR haploinsufficiency in mice.
V. Herrera, J. Decano, P. Bagamasbad, Timothy Kufahl +2 more
2008Physiological Genomics15 citations Open access
Semantic Scholar
Sex-specific genetic determinants for arterial stiffness in Dahl salt-sensitive hypertensive rats
J. Decano, K. A. Pasion, N. Black, Nicholas J. Giordano +2 more
2016BMC Genetics12 citations Open access
Semantic Scholar
Analysis of cd45- [cd34+/kdr+] Endothelial Progenitor Cells as Juvenile Protective Factors in a Rat Model of Ischemic-Hemorrhagic Stroke
J. Decano, A. Moran, Nicholas J. Giordano, N. Ruiz‐Opazo +1 more
2013PLoS ONE12 citations Open access
Semantic Scholar
Overlapping genes in Nalp6/PYPAF5 locus encode two V2-type vasopressin isoreceptors: angiotensin-vasopressin receptor (AVR) and non-AVR.
V. Herrera, P. Bagamasbad, T. Didishvili, J. Decano +1 more
2008Physiological Genomics12 citations Open access
Semantic Scholar
Decoding macrophage heterogeneity to unravel vascular inflammation as a path to precision medicine
S. Chelvanambi, J. Decano, Holger Winkels, Chiara Giannarelli +1 more
2024Arteriosclerosis, Thrombosis and Vascular Biology9 citations Open access
Semantic Scholar
Preoperative methionine restriction induces perivascular adipose tissue browning and improves vein graft remodeling in male mice
Peter Kip, T. Sluiter, Michael R. MacArthur, Ming Tao +12 more
2024Nature Communications8 citations Open access
Semantic Scholar
Obesity and age are transmission risk factors for SARS-CoV-2 infection among exposed individuals
J. Matamalas, S. Chelvanambi, J. Decano, Raony F França +5 more
2024PNAS Nexus8 citations Open access
Semantic Scholar
AVR/NAVR deficiency lowers blood pressure and differentially affects urinary concentrating ability, cognition, and anxiety-like behavior in male and female mice.
V. Herrera, P. Bagamasbad, J. Decano, N. Ruiz‐Opazo
2011Physiological Genomics8 citations Open access
Semantic Scholar
Janus USPION modular platform (JUMP) for theranostic ultrasound-mediated targeted intratumoral microvascular imaging and DNA/miRNA delivery
R. Whitaker, J. Decano, Catherine A Gormley, Carl A. Beigie +12 more
2022Theranostics7 citations Open access
Semantic Scholar
Integrating pharmacogenomics and cheminformatics with diverse disease phenotypes for cell type-guided drug discovery
A. Halu, S. Chelvanambi, J. Decano, J. Matamalas +6 more
2022bioRxiv6 citations Open access
Semantic Scholar
Hyperedge Entanglement in High-Order Multilayer Networks
A. Muscoloni, Ilyes Abdelhamid, J. Decano, E. Souza +5 more
20203 citations Open access
Semantic Scholar
Arteriosclerosis, Thrombosis
Arterioscler Thromb, Vasc Biol, Diego V. Santinelli-Pestana, Constance Delwarde +14 more
3 citations
Semantic Scholar
Autophagy: Insights from DEspR-deficiency and haploinsufficiency
V. Herrera, J. Decano, Martin A. Steffen, N. Ruiz‐Opazo
2009Autophagy2 citations Open access
Semantic Scholar
The long noncoding RNA lnc-FAM164A1-ACLY axis promotes pro-inflammatory responses in human primary macrophages: a systems approach
Jian-Guo Wang, Shiori Ito, Daiki Hosokawa, Keishi Nihira +15 more
2026Frontiers in Immunology1 citations Open access
Semantic Scholar
Anti-DEspR antibody treatment improves survival and reduces neurologic deficits in a hypertensive, spontaneous intracerebral hemorrhage (hsICH) rat model
V. Herrera, Christopher M Gromisch, J. Decano, K. A. Pasion +5 more
2023Scientific Reports1 citations Open access
Semantic Scholar
3.9 Gender-Specific Association of ATP1a1 and Dear Haplotypes with Essential Hypertension
N. Glorioso, V. Herrera, P. Bagamasbad, F. Filigheddu +7 more
20071 citations Open access
Semantic Scholar
Nuclear RSK1 mediates interferon-γ–induced proinflammatory activation in human primary macrophages and humanized mice
Keishi Nihira, Yoshihiro Yanagihara, Yuto Nakamura, S. Chelvanambi +13 more
2026Science Advances0 citations Open access
Semantic Scholar
ADP-ribosylation in a mouse model of atherosclerosis: A potential novel link between dyslipidemia and inflammation in cardiovascular disease
C. Delwarde, D. Pestana, Taku Kasai, S. Kuraoka +11 more
2025Archives of Cardiovascular Diseases0 citations
Semantic Scholar
Abstract 4120480: HIV-Nef extracellular vesicles utilize the novel Btk-NFκB-MerTK signaling axis to impair macrophage efferocytosis and promote atherosclerosis: A multiomics study
S. Chelvanambi, J. Decano, Yuto Nakamura, Yoshihiro Yangihara +20 more
2024Circulation0 citations
Semantic Scholar
Abstract 4131674: ADP-Ribosylation In a Mouse Model of Atherosclerosis: a Potential Novel Link Between Dyslipidemia and Inflammation in Cardiovascular Disease
Constance Delwarde, D. Pestana, Taku Kasai, S. Kuraoka +12 more
2024Circulation0 citations
Semantic Scholar
Abstract 15540: Single Cell Transcriptional-Epigenetic Profiling and Sub-Cellular Proteomics Demonstrate That HIV-Nef Extracellular Vesicles Modulate Human Macrophage Heterogeneity to Promote Atherosclerosis
S. Chelvanambi, J. Decano, Rile Ge, Yoshihiro Yanagihara +17 more
2022Circulation0 citations
Semantic Scholar
Abstract 112: Examining The Heterogeneity Of Primary Human Macrophages And Pharmacogenomic Networks To Identify Novel Targets For Precision Medicine For Vascular Inflammation
J. Decano, E. Maiorino, J. Matamalas, S. Chelvanambi +10 more
2021Arteriosclerosis, Thrombosis and Vascular Biology0 citations
Semantic Scholar
Abstract 11752: Pitavastatin Treatment Ameliorates HIV-Nef Containing Extracellular Vesicle-Mediated Cardiomyocyte Dysfunction
S. Chelvanambi, J. Decano, S. Kuraoka, E. Aikawa +2 more
2021Circulation0 citations
Semantic Scholar
Abstract 13820: Systems Biology of Arteriovenous Fistula to Explore Novel Mechanistic Insights and Therapeutic Targets
J. Decano, C. G. Bueno, Gabriela A. Quieroz Do-Amaral, Lang-Ho Lee +6 more
20190 citations
Semantic Scholar
Systems Approach Identified PPARα as a Therapeutic Target for Vein Graft Disease: the Effects of the Specific Activator Pemafibrate on Macrophage Activation
J. Decano, Heng-Min Zhang, Sasha A. Singh, Lang H. Lee +8 more
2018Atherosclerosis Supplements0 citations
Semantic Scholar
Abstract 663: Nuclear RSK1 Induces Pro-inflammatory Activation of Macrophages through STAT1 Phosphorylation at Ser727
Keishi Nihira, A. Halu, L. Ho, Alexander Mojcher +8 more
20180 citations
Semantic Scholar
Abstract 329: Systems-based Target Discovery Reveals PPARa as a Key Metabolic Regulator for Macrophage Activation in Vein Graft Disease
J. Decano, Heng-Min Zhang, Sasha A. Singh, Andrew K. Mlynarchik +14 more
20180 citations
Semantic Scholar
Mouse Models of Atherosclerosis
H. Iwata, Jun-ichiro Koga, J. Decano, Choi Jung +4 more
20160 citations
Semantic Scholar
Sex-specific genetic determinants for arterial stiffness in Dahl salt-sensitive hypertensive rats
J. Decano, K. A. Pasion, N. Black, Nicholas J. Giordano +2 more
2016BMC Genetics0 citations Open access
Semantic Scholar
angiotensin-vasopressin receptor (AVR) and non-AVR V2-type vasopressin isoreceptors: locus encode two Nalp6/PYPAF5 Overlapping genes in
N. Ruiz‐Opazo, V. Herrera, P. Bagamasbad, T. Didishvili +15 more
20150 citations
Semantic Scholar
player in angiogenesis gene-deficient mice: new Dear Embryonic lethality in
T. Didishvili, N. Ruiz‐Opazo, V. Herrera, L. Ponce +11 more
20150 citations
Semantic Scholar
Anti-tumor effects of DEspR-inhibition in Panc1-CSC xenograft tumors in nude rats.
V. Herrera, J. Decano, Glaiza L. A. Tan, A. Moran +3 more
20140 citations Open access
Semantic Scholar
Dual endothelin-1/VEGFsp receptor (DEspR): Common target on tumor vascular endothelial cells (TVECs), tumor cells (TCs), and cancer stem cells (CSCs) in glioblastoma and pancreatic cancer.
V. Herrera, Glaiza L. A. Tan, A. Moran, K. Pasion +2 more
20120 citations
Semantic Scholar
AVR/NAVR deﬁciency lowers blood pressure and differentially affects urinary concentrating ability, cognition, and anxiety-like behavior in male and female mice
V. Herrera, P. Bagamasbad, J. Decano, N. Ruiz‐Opazo
20100 citations
Semantic Scholar

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V. Herrera — researcher profile on SciRah
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