Researcher profile · Semantic Scholar

H. Hirbec

h-index: 19
Works: 39
Citations: 1,875

Most-cited papers

Microglia in Alzheimer Disease: Well-Known Targets and New Opportunities
A. Hemonnot, Jennifer Hua, L. Ulmann, H. Hirbec
2019Frontiers in Aging Neuroscience268 citations Open access
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P2X4 receptors mediate PGE2 release by tissue‐resident macrophages and initiate inflammatory pain
L. Ulmann, H. Hirbec, F. Rassendren
2010EMBO Journal228 citations Open access
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Rapid and Differential Regulation of AMPA and Kainate Receptors at Hippocampal Mossy Fibre Synapses by PICK1 and GRIP
H. Hirbec, J. C. Francis, S. Lauri, S. Braithwaite +8 more
2003Neuron213 citations Open access
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Acute exposure to GSM 900-MHz electromagnetic fields induces glial reactivity and biochemical modifications in the rat brain.
Anne-Laure Mausset-Bonnefont, H. Hirbec, X. Bonnefont, A. Privat +2 more
2004Neurobiology of Disease144 citations Open access
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The PDZ Proteins PICK1, GRIP, and Syntenin Bind Multiple Glutamate Receptor Subtypes
H. Hirbec, O. Perestenko, A. Nishimune, G. Meyer +3 more
2002Journal of Biological Chemistry143 citations Open access
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Involvement of P2X4 receptors in hippocampal microglial activation after status epilepticus
L. Ulmann, F. Levavasseur, E. Avignone, R. Peyroutou +3 more
2013Glia111 citations
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Dopamine D2High receptors stimulated by phencyclidines, lysergic acid diethylamide, salvinorin A, and modafinil
P. Seeman, Hong-Chang Guan, H. Hirbec
2009Synapse86 citations
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Microglia Responses in Acute and Chronic Neurological Diseases: What Microglia-Specific Transcriptomic Studies Taught (and did Not Teach) Us
H. Hirbec, H. Noristani, F. Perrin
2017Frontiers in Aging Neuroscience72 citations Open access
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Src kinase activation is mandatory for MDA-9/syntenin-mediated activation of Nuclear Factor-κB
H. Boukerche, H. Aissaoui, C. Prévost, H. Hirbec +4 more
2010Oncogene71 citations Open access
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RNA-Seq Analysis of Microglia Reveals Time-Dependent Activation of Specific Genetic Programs following Spinal Cord Injury
H. Noristani, Y. Gerber, J. Sabourin, M. le Corre +4 more
2017Frontiers in Molecular Neuroscience66 citations Open access
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Gacyclidine: a new neuroprotective agent acting at the N-methyl-D-aspartate receptor.
H. Hirbec, M. Gaviria, J. Vignon
2006CNS drug reviews63 citations Open access
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Regulation of kainate receptors by protein kinase C and metabotropic glutamate receptors
Kwangwook Cho, J. C. Francis, H. Hirbec, K. Dev +3 more
2003Journal of Physiology57 citations
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Syntenin is involved in the developmental regulation of neuronal membrane architecture.
H. Hirbec, S. Martin, J. Henley
2005Molecular and cellular neurosciences54 citations
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Emerging technologies to study glial cells
H. Hirbec, N. Déglon, Lynette C. Foo, I. Goshen +8 more
2020Glia38 citations
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The microglial reaction signature revealed by RNAseq from individual mice
H. Hirbec, Camille Marmai, I. Duroux-Richard, C. Roubert +5 more
2018Glia38 citations
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Prenatal infection obliterates glutamate‐related protection against free hydroxyl radicals in neonatal rat brain
G. Cambonie, H. Hirbec, M. Michaud, J. Kamenka +1 more
2004Journal of Neuroscience Research26 citations
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RNA Profiling of Mouse Ependymal Cells after Spinal Cord Injury Identifies the Oncostatin Pathway as a Potential Key Regulator of Spinal Cord Stem Cell Fate
R. Chevreau, H. Ghazale, C. Ripoll, C. Chalfouh +10 more
2021Cells24 citations Open access
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Evidence for Status Epilepticus and Pro-Inflammatory Changes after Intranasal Kainic Acid Administration in Mice
Mounira Sabilallah, P. Fontanaud, N. Linck, Badreddine Boussadia +5 more
2016PLoS ONE23 citations Open access
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Comparative analysis of transcriptome remodeling in plaque-associated and plaque-distant microglia during amyloid-β pathology progression in mice
Anne-Laure Hemonnot-Girard, Cédric Meersseman, M. Pastore, V. García +9 more
2022Journal of Neuroinflammation21 citations Open access
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Microglia Reactivity: Heterogeneous Pathological Phenotypes.
H. Hirbec, F. Rassendren, E. Audinat
2019Methods in molecular biology18 citations
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Analysis of CX3CR1 haplodeficiency in male and female APPswe/PSEN1dE9 mice along Alzheimer disease progression.
Anne-Laure Hemonnot-Girard, Audrey Valverde, Jennifer Hua, Charlene Delaygue +4 more
2020Brain, behavior, and immunity16 citations Open access
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Comparison of the pharmacological properties of GK11 and MK801, two NMDA receptor antagonists: towards an explanation for the lack of intrinsic neurotoxicity of GK11
D. Vandame, G. Desmadryl, J. B. Ortega, M. Teigell +4 more
2007Journal of Neurochemistry16 citations Open access
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Binding properties of [3H]gacyclidine (cis(pip/me)-1-[1-(2-thienyl)-2-methylcyclohexyl]piperidine) enantiomers in the rat central nervous system.
H. Hirbec, J. Teilhac, J. Kamenka, A. Privat +1 more
2000Brain Research15 citations
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Development of NMDAR Antagonists with Reduced Neurotoxic Side Effects: a Study on GK11
D. Vandame, L. Ulmann, Marisa Teigell, Monica Prieto-Cappellini +5 more
2013PLoS ONE14 citations Open access
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Interaction of gacyclidine enantiomers with 'non-NMDA' binding sites in the rat central nervous system.
H. Hirbec, J. Kamenka, A. Privat, J. Vignon
2001Brain Research12 citations
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Re‐evaluation of phencyclidine low‐affinity or “non‐NMDA” binding sites
H. Hirbec, A. Mausset, Jean Marc Kamenka, A. Privat +1 more
2002Journal of Neuroscience Research8 citations
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Binding properties of [3H]gacyclidine in the rat central nervous system.
H. Hirbec, A. Privat, Jacques Vignon
2000European Journal of Pharmacology8 citations Open access
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Characterization of ‘non-N-methyl-d-Aspartate’ binding sites for gacyclidine enantiomers in the rat cerebellar and telencephalic structures
H. Hirbec, J. Kamenka, A. Privat, J. Vignon
20017 citations
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The low affinity PCP sites in the rat cerebellum not only bind TCP-like but also BTCP-like structures.
Florence Espaze, Jacques Hamon, H. Hirbec, Jacques Vignon +1 more
2000European journal of medicinal chemistry7 citations
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Characterization of ‘non‐N‐methyl‐d‐Aspartate’ binding sites for gacyclidine enantiomers in the rat cerebellar and telencephalic structures
H. Hirbec, Jean Marc Kamenka, A. Privat, J. Vignon
2001Journal of Neurochemistry4 citations
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[New technologies to unveil the role of brain glial cells].
Anne-Laure Hemonnot-Girard, Lucile Ben Haim, C. Escartin, H. Hirbec
2021Medecine sciences : M/S3 citations Open access
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Reaction of ependymal cells to spinal cord injury: a potential role for oncostatin pathway and microglial cells
R. Chevreau, H. Ghazale, C. Ripoll, C. Chalfouh +8 more
2021bioRxiv1 citations Open access
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The 19th Ion Channel Meeting, September 2008, France
D. Bichet, C. Duranton, H. Hirbec, S. Kellenberger +3 more
2009Channels0 citations Open access
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Erratum Rapid and Differential Regulation of AMPA and Kainate Receptors at Hippocampal Mossy Fibre Synapses by PICK 1 and GRIP
H. Hirbec, J. C. Francis, S. Lauri, S. Braithwaite +8 more
2003Neuron0 citations Open access
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Effects of high power 900 Mhz microwaves on neurotransmission in the rat brain
A. Mausset, H. Hirbec, J. Vignon, A. Privat +1 more
20020 citations
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Syntenin interacts with kainate receptors: in vitro and in vivo evidence
H. Hirbec, S. Lauri, J. C. Francis, S. Braithwaite +3 more
20010 citations
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Use of GST pull-down assays to identify new interactions between the PICK1 and GRIP proteins and the glutamate receptors
O. Perestenko, H. Hirbec, K. Dev, A. Nishimune +3 more
20010 citations
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Characterisation of The Interaction Between The Kainate Receptor Subunit, GluR5-2b and PICK1
J. C. Francis, H. Hirbec, S. Braithwaite, K. Dev +1 more
20010 citations
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The Low Affinity PCP Sites in the Rat Cerebellum Not only Bind TCP‐Like but also BTCP‐Like Structure.
F. Espaze, Jacques Hamon, H. Hirbec, J. Vignon +1 more
20000 citations
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K. Dev

×6

A. Privat×6

L. Ulmann×5

J. Kamenka×5

S. Braithwaite×4

G. Meyer×4

A. Privat×4

H. Noristani×4