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S. Iram · SciRah

Researcher profile · Semantic Scholar

S. Iram

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S. Iram — researcher profile on SciRah

h-index: 14
Works: 28
Citations: 556

Most-cited papers

The β-Oxidation Systems of Escherichia coli and Salmonella enterica Are Not Functionally Equivalent
S. Iram, J. Cronan
2006Journal of Bacteriology79 citations Open access
Semantic Scholar
Unexpected Functional Diversity among FadR Fatty Acid Transcriptional Regulatory Proteins*
S. Iram, J. Cronan
2005Journal of Biological Chemistry56 citations Open access
Semantic Scholar
Roles of the Glycogen-binding Domain and Snf4 in Glucose Inhibition of SNF1 Protein Kinase*
M. Momcilovic, S. Iram, Yang Liu, M. Carlson
2008Journal of Biological Chemistry49 citations Open access
Semantic Scholar
High‐content screening of clinically tested anticancer drugs identifies novel inhibitors of human MRP1 (ABCC1)
B. G. Peterson, Kee W. Tan, Bremansu Osa-Andrews, S. Iram
2017Pharmacological Research42 citations Open access
Semantic Scholar
Doxorubicin as a fluorescent reporter identifies novel MRP1 (ABCC1) inhibitors missed by calcein-based high content screening of anticancer agents.
A. Sampson, B. G. Peterson, Kee W. Tan, S. Iram
2019Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie41 citations Open access
Semantic Scholar
Structure of the Bateman2 domain of yeast Snf4: dimeric association and relevance for AMP binding.
M. Rudolph, G. Amodeo, S. Iram, Seung-pyo Hong +3 more
2007Structure34 citations Open access
Semantic Scholar
Expression and Function of Human MRP1 (ABCC1) Is Dependent on Amino Acids in Cytoplasmic Loop 5 and Its Interface with Nucleotide Binding Domain 2*
S. Iram, S. Cole
2010Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Mutation of Glu521 or Glu535 in Cytoplasmic Loop 5 Causes Differential Misfolding in Multiple Domains of Multidrug and Organic Anion Transporter MRP1 (ABCC1)*
S. Iram, S. Cole
2012Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Calcitriol and Calcipotriol Modulate Transport Activity of ABC Transporters and Exhibit Selective Cytotoxicity in MRP1-overexpressing Cells
Kee W. Tan, A. Sampson, Bremansu Osa-Andrews, S. Iram
2018Drug Metabolism And Disposition29 citations Open access
Semantic Scholar
A critical review on modulators of Multidrug Resistance Protein 1 in cancer cells
Vivian Osei Poku, S. Iram
2022PeerJ25 citations Open access
Semantic Scholar
Rheumatoid arthritis treatment using hydroxychloroquine and methotrexate co-loaded nanomicelles: In vivo results
Tais Monteiro Magne, Edward Helal-Neto, L. B. Correa, L. M. Rebêlo Alencar +8 more
2021Colloids and Surfaces B: Biointerfaces23 citations Open access
Semantic Scholar
ATP–Binding Cassette Transporter Structure Changes Detected by Intramolecular Fluorescence Energy Transfer for High-Throughput Screening
S. Iram, Simon J. Gruber, Olga N. Raguimova, David D. Thomas +1 more
2015Molecular Pharmacology21 citations Open access
Semantic Scholar
Radioactive gold nanocluster (198-AuNCs) showed inhibitory effects on cancer cells lines
Shi-Jin Xuan, Aline Oliveira da Silva de Barros, R. C. Nunes, Eduardo Ricci-Júnior +8 more
2020Artificial Cells Nanomedicine and Biotechnology18 citations Open access
Semantic Scholar
Preliminary studies on drug delivery of polymeric primaquine microparticles using the liver high uptake effect based on size of particles to improve malaria treatment.
Aline Oliveira da Silva de Barros, Filipe Leal Portilho, Ana Paula dos Santos Matos, Eduardo Ricci-Júnior +8 more
2021Materials Science and Engineering C: Materials for Biological Applications17 citations
Semantic Scholar
Differential functional rescue of Lys(513) and Lys(516) processing mutants of MRP1 (ABCC1) by chemical chaperones reveals different domain-domain interactions of the transporter.
S. Iram, S. Cole
2014Biochimica et Biophysica Acta13 citations Open access
Semantic Scholar
Triazole-estradiol analogs: A potential cancer therapeutic targeting ovarian and colorectal cancer.
Trevor Ostlund, Faez Alotaibi, Jennifer Kyeremateng, Hossam Halaweish +3 more
2021Steroids12 citations
Semantic Scholar
The Effect of Nanosystems on ATP-Binding Cassette Transporters: Understanding the Influence of Nanosystems on Multidrug Resistance Protein-1 and P-glycoprotein
Francisco V. C. Mello, G. N. de Moraes, R. Maia, Jennifer Kyeremateng +2 more
2020International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
Development of Novel Intramolecular FRET-Based ABC Transporter Biosensors to Identify New Substrates and Modulators
Bremansu Osa-Andrews, Kee W. Tan, A. Sampson, S. Iram
2018Pharmaceutics10 citations Open access
Semantic Scholar
Biophysical Approaches Facilitate Computational Drug Discovery for ATP-Binding Cassette Proteins
Steven V. Molinski, Z. Bozoky, S. Iram, Saumel Ahmadi
2017International Journal of Medicinal Chemistry6 citations Open access
Semantic Scholar
Novel EGFR‐MAPK kinase and ABC transporter inhibitors for HepG2 resistant to Erlotinib
Trevor Ostlund, Kakan Sutradhar, Sara M. Elgazwi, M. Mahnashi +3 more
2022Drug development research (Print)4 citations
Semantic Scholar
Identification of FDA-Approved Drugs as Modulators of Multidrug Resistance Protein 2 (MRP2/ABCC2) Expression Levels in MRP2-Overexpressing Cells: Preliminary Data
Vivian Osei Poku, S. Iram
2024The Journal of Bioscience and Medicine1 citations Open access
Semantic Scholar
High-content Screening of Clinically Tested Anticancer Drugs Identifies Novel Inhibitors of Human MRP 1 ( ABCC 1 )
B. G. Peterson, Kee W. Tan, Bremansu Osa-Andrews, S. Iram
20191 citations
Semantic Scholar
A Cell Based Assay to Identify Efflux Activity of MRP1 on Some MRP1 Modulators
N. Uddin, Md Sajjadur Rahman, Jennifer Kyeremateng, S. Iram +1 more
2021Social Science Research Network0 citations Open access
Semantic Scholar
Evaluation of FDA Drugs to Identify Modulators of Multidrug Resistance Associated Protein 1 (MRP1) Expression Levels in HEK293 MRP1 Overexpressing Cells.
Josh Loecker, Vivian Osei Poku, S. Iram
2020The FASEB Journal0 citations Open access
Semantic Scholar
Transporter Associated with Antigen Processing The ABCs of Immunology: Structure and Function of TAP, the
R. Tampé, Smriti Mishra, Po-Chao Wen, E. Tajkhorshid +10 more
20150 citations
Semantic Scholar
Structural Dynamics of the Human MRP1 Drug Transporter Revealed by Fluorescence Resonance Energy Transfer
S. Iram, S. Robia
20140 citations Open access
Semantic Scholar
Crystal structure of the Bateman2 domain of yeast Snf4
M. Rudolph, G. Amodeo, S. Iram, Seung-pyo Hong +3 more
20060 citations
Semantic Scholar
Fatty Acid Degradation in Escherichia Coli and Salmonella Enterica Serovar Typhimurium
S. Iram
20050 citations
Semantic Scholar

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