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E. Chastre · SciRah

Researcher profile · Semantic Scholar

E. Chastre

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E. Chastre — researcher profile on SciRah

h-index: 32
Works: 68
Citations: 4,319

Most-cited papers

Overexpression and amplification of the met/HGF receptor gene during the progression of colorectal cancer.
M. D. Di Renzo, Martina Olivero, A. Giacomini, H. Porte +6 more
1995Clinical Cancer Research471 citations
Semantic Scholar
Evidence for a Role of Rho-like GTPases and Stress-activated Protein Kinase/c-Jun N-terminal Kinase (SAPK/JNK) in Transforming Growth Factor β-mediated Signaling*
A. Atfi, S. Djelloul, E. Chastre, R. Davis +1 more
1997Journal of Biological Chemistry321 citations Open access
Semantic Scholar
Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors
P. Jordan, Raquel BrazÃ£o, M. Boavida, C. Gespach +1 more
1999Oncogene279 citations Open access
Semantic Scholar
Phosphorylation of inositol 1,4,5-trisphosphate receptors by protein kinase B/Akt inhibits Ca2+ release and apoptosis
T. Szado, Veerle Vanderheyden, J. Parys, H. De Smedt +8 more
2008Proceedings of the National Academy of Sciences of the United States of America257 citations Open access
Semantic Scholar
Leptin promotes invasiveness of kidney and colonic epithelial cells via phosphoinositide 3‐kinase‐, Rho‐, and Rac‐dependent signaling pathways
S. Attoub, Veerle Noe, L. Pirola, E. Bruyneel +4 more
2000The FASEB Journal240 citations
Semantic Scholar
Loss of sst2 somatostatin receptor gene expression in human pancreatic and colorectal cancer.
L. Buscail, N. Saint-Laurent, E. Chastre, J. Vaillant +6 more
1996Cancer Research218 citations
Semantic Scholar
Neoplastic progression of human colorectal cancer is associated with overexpression of the stromelysin‐3 and BM‐40/SPARC genes
H. Porte, E. Chastre, S. Prévôt, B. Nordlinger +4 more
1995International Journal of Cancer189 citations
Semantic Scholar
Implication of the MAGI‐1b/PTEN signalosome in stabilization of adherens junctions and suppression of invasiveness
L. Kotelevets, J. Hengel, E. Bruyneel, M. Mareel +2 more
2005The FASEB Journal170 citations
Semantic Scholar
Vegf, vegf‐B, vegf‐C and their receptors KDR, FLT‐1 and FLT‐4 during the neoplastic progression of human colonic mucosa
T. André, L. Kotelevets, J. Vaillant, A. Coudray +5 more
2000International Journal of Cancer161 citations Open access
Semantic Scholar
Evidence for the involvement of the Wnt 2 gene in human colorectal cancer.
Ben-Zion Vider, A. Zimber, E. Chastre, S. Prévôt +6 more
1996Oncogene126 citations
Semantic Scholar
The lipid phosphatase activity of PTEN is critical for stabilizing intercellular junctions and reverting invasiveness
L. Kotelevets, J. van Hengel, E. Bruyneel, M. Mareel +2 more
2001Journal of Cell Biology125 citations Open access
Semantic Scholar
Leptin stimulates the proliferation of human colon cancer cells in vitro but does not promote the growth of colon cancer xenografts in nude mice or intestinal tumorigenesis in ApcMin/+ mice
Thomas Aparicio, L. Kotelevets, A. Tsocas, J. Laigneau +3 more
2005Gut123 citations Open access
Semantic Scholar
Gastric M1 mucin, an early oncofetal marker of colon carcinogenesis, is encoded by the MUC5AC gene
J. Bara, E. Chastre, J. Mahiou, Rupachandra L. Singh +3 more
1998International Journal of Cancer120 citations Open access
Semantic Scholar
Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells.
Cécile Guichard, E. Pédruzzi, M. Fay, J. Marie +10 more
2006Carcinogenesis116 citations
Semantic Scholar
Resistin‐like molecule &bgr; regulates intestinal mucous secretion and curtails TNBS‐induced colitis in mice
R. B. Krimi, L. Kotelevets, L. Dubuquoy, P. Plaisancié +7 more
2008Inflammatory Bowel Diseases105 citations
Semantic Scholar
Overexpression of stromelysin-3, BM-40/SPARC, and MET genes in human esophageal carcinoma: implications for prognosis.
H. Porte, J. Triboulet, Larissa Kotelevets, Fabrice Carrat +7 more
1998Clinical Cancer Research105 citations
Semantic Scholar
Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2
S. Moniz, F. Veríssimo, P. Matos, R. Brazão +5 more
2007Oncogene81 citations
Semantic Scholar
Rac1 Signaling: From Intestinal Homeostasis to Colorectal Cancer Metastasis
L. Kotelevets, E. Chastre
2020Cancers78 citations Open access
Semantic Scholar
Inhibition by Platelet-activating Factor of Src- and Hepatocyte Growth Factor-dependent Invasiveness of Intestinal and Kidney Epithelial Cells
L. Kotelevets, V. Noë, E. Bruyneel, E. Myssiakine +3 more
1998Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Distinct functional outputs of PTEN signalling are controlled by dynamic association with β‐arrestins
Evelyne Lima-Fernandes, H. Enslen, Emeline Camand, L. Kotelevets +10 more
2011EMBO Journal72 citations Open access
Semantic Scholar
TRIP6, a novel molecular partner of the MAGI‐1 scaffolding molecule, promotes invasiveness
E. Chastre, Mahmoud Abdessamad, A. Kruglov, E. Bruyneel +5 more
2009The FASEB Journal69 citations
Semantic Scholar
A Squalene-Based Nanomedicine for Oral Treatment of Colon Cancer.
L. Kotelevets, E. Chastre, Joachim Caron, J. Mougin +6 more
2017Cancer Research66 citations
Semantic Scholar
Nanotechnologies for the treatment of colon cancer: From old drugs to new hope.
L. Kotelevets, E. Chastre, D. Desmaële, P. Couvreur
2016International journal of pharmaceutics60 citations
Semantic Scholar
Differential expression of the CCK‐A and CCK‐B/gastrin receptor genes in human cancers of the esophagus, stomach and colon
P. Clerc, M. Dufresne, Corinne Saillan, E. Chastre +6 more
1997International Journal of Cancer60 citations Open access
Semantic Scholar
Enterocyte differentiation is compatible with SV40 large T expression and loss of p53 function in human colonic Caco‐2 cells
S. Djelloul, M. Forgue-Lafitte, B. Hermelin, M. Mareel +5 more
1997FEBS Letters55 citations Open access
Semantic Scholar
Progression of familial adenomatous polyposis (FAP) colonic cells after transfer of the src or polyoma middle T oncogenes: cooperation between src and HGF/Met in invasion.
S. Empereur, S. Djelloul, Y. Digioia, E. Bruyneel +8 more
1997British Journal of Cancer52 citations Open access
Semantic Scholar
Posttranslational Regulation and Conformational Plasticity of PTEN.
L. Kotelevets, Barbara Trifault, E. Chastre, M. Scott
2020Cold Spring Harbor Perspectives in Medicine42 citations Open access
Semantic Scholar
Ibuprofen inhibits colitis-induced overexpression of tumor-related Rac1b.
P. Matos, L. Kotelevets, V. Gonçalves, Andreai F. A. Henriques +5 more
2013Neoplasia38 citations Open access
Semantic Scholar
Extracellular Vesicles in Colorectal Cancer: From Tumor Growth and Metastasis to Biomarkers and Nanomedications
L. Kotelevets, E. Chastre
2023Cancers37 citations Open access
Semantic Scholar
Interaction of VIP, PACAP and related peptides in normal and leukemic human monocytes and macrophages
A. Chedeville, L. Mirossay, E. Chastre, I. Hurbain-Kosmath +2 more
1993FEBS Letters33 citations Open access
Semantic Scholar
B-ind1, a Novel Mediator of Rac1 Signaling Cloned from Sodium Butyrate-treated Fibroblasts*
D. Courilleau, E. Chastre, M. Sabbah, G. Redeuilh +2 more
2000Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Extracellular regulation of cancer invasion: the E-cadherin-catenin and other pathways.
V. Noë, E. Chastre, E. Bruyneel, C. Gespach +1 more
1999Biochemical Society Symposium32 citations
Semantic Scholar
Targeting PTEN in Colorectal Cancers.
L. Kotelevets, M. Scott, E. Chastre
2018Advances in Experimental Medicine and Biology31 citations
Semantic Scholar
Human cord blood monocytes undergo terminal osteoclast differentiation in vitro in the presence of culture medium conditioned by giant cell tumor of bone
S. Roux, J. Quinn, Frank Pichaud, P. Orcel +3 more
1996Journal of Cellular Physiology30 citations
Semantic Scholar
Functional expression of receptors for calcitonin gene-related peptide, calcitonin, and vasoactive intestinal peptide in the human thymus and thymomas from myasthenia gravis patients.
Julien C. Marie, A. Wakkach, A. Coudray, E. Chastre +2 more
1999Journal of Immunology29 citations
Semantic Scholar
Vasoactive intestinal peptide receptor activity and specificity during enterocyte‐like differentiation and retrodifferentiation of the human colonic cancerous subclone HT29‐18
E. Chastre, S. Emami, G. Rosselin, C. Gespach
1985FEBS Letters26 citations Open access
Semantic Scholar
Functional receptors for VIP, GIP, glucagon-29 and -37 in the HGT-1 human gastric cancer cell line.
S. Emami, E. Chastre, H. Bodéré, C. Gespach +2 more
1986Peptides21 citations
Semantic Scholar
A New Story of the Three Magi: Scaffolding Proteins and lncRNA Suppressors of Cancer
L. Kotelevets, E. Chastre
2021Cancers20 citations Open access
Semantic Scholar
Vasoactive intestinal peptide receptor activity in human fetal enterocytes
C. Gespach, E. Chastre, S. Emami, N. Mulliez
1985FEBS Letters18 citations Open access
Semantic Scholar
The Rac1 splice form Rac1b favors mouse colonic mucosa regeneration and contributes to intestinal cancer progression
L. Kotelevets, F. Walker, Godefroy Mamadou, T. Lehy +2 more
2018Oncogene17 citations
Semantic Scholar
Evidence for different expression profiles for c-Met, EGFR, PTEN and the mTOR pathway in low and high grade endometrial carcinomas in a cohort of consecutive women. Occurrence of PIK3CA and K-Ras mutations and microsatellite instability.
A. Thoury, V. Descatoire, L. Kotelevets, C. Kannengiesser +8 more
2014Histology and Histopathology16 citations
Semantic Scholar
Prostaglandin E₂ induced contraction of human intercostal arteries is mediated by the EP₃ receptor.
D. Longrois, I. Gomez, N. Foudi, G. Topal +4 more
2012European Journal of Pharmacology16 citations
Semantic Scholar
Identification of mitogen‐activated protein/extracellular signal‐responsive kinase kinase 2 as a novel partner of the scaffolding protein human homolog of disc‐large
Oumou Maïga, Monique Philippe, L. Kotelevets, E. Chastre +4 more
2011The FEBS Journal14 citations Open access
Semantic Scholar
[Tumoral angiogenesis: physiopathology, prognostic value and therapeutic perspectives].
T. André, E. Chastre, L. Kotelevets, J. Vaillant +5 more
1998La Revue de medecine interne14 citations
Semantic Scholar
VIP receptor activity during HT29-18 cell differentiation and rat intestinal development.
E. Chastre, S. Emami, C. Gespach
1986Peptides11 citations
Semantic Scholar
Decreased vasorelaxation induced by iloprost during acute inflammation in human internal mammary artery
N. Foudi, G. Ozen, Yasmine Amgoud, L. Louedec +6 more
2017European Journal of Pharmacology9 citations
Semantic Scholar
Functional and structural characterization of the secretin receptors in rat gastric glands: Desensitization and glycoprotein nature
W. Bawab, E. Chastre, C. Gespach
1991Bioscience Reports9 citations
Semantic Scholar
Membrane receptors in the gastrointestinal tract
C. Gespach, S. Emami, E. Chastre
19888 citations
Semantic Scholar
Protein kinase WNK2 inhibits cell proliferation by negatively modulating the activation of MEK1/ERK1/2
S. Moniz, F. Veríssimo, P. Matos, R. Brazão +5 more
2008Oncogene5 citations Open access
Semantic Scholar
Ibuprofen Inhibits Colitis-Induced Overexpression of Tumor-
P. Matos, L. Kotelevets, V. Gonçalves, A. Henriques +4 more
20134 citations
Semantic Scholar

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