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T. Glover · SciRah

Researcher profile · Semantic Scholar

T. Glover

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T. Glover — researcher profile on SciRah

h-index: 55
Works: 122
Citations: 16K

Most-cited papers

Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome
M. Eriksson, W. Brown, L. Gordon, Michael W. Glynn +13 more
2003Nature2,222 citations Open access
Semantic Scholar
Mutations in FOXC2 (MFH-1), a forkhead family transcription factor, are responsible for the hereditary lymphedema-distichiasis syndrome.
Jian-Ming Fang, S. Dagenais, R. Erickson, Martin F. Arlt +4 more
2000American Journal of Human Genetics644 citations Open access
Semantic Scholar
DNA polymerase α inhibition by aphidicolin induces gaps and breaks at common fragile sites in human chromosomes
T. Glover, C. Berger, J. Coyle, B. Echo
2004Human Genetics452 citations
Semantic Scholar
Somatic deletion of the neurofibromatosis type 1 gene in a neurofibrosarcoma supports a tumour suppressor gene hypothesis
E. Legius, D. Marchuk, F. Collins, T. Glover
1993Nature Genetics395 citations
Semantic Scholar
Chromosome fragile sites.
Sandra G. Durkin, T. Glover
2007Annual Review of Genetics335 citations
Semantic Scholar
The Fanconi anemia pathway is required for the DNA replication stress response and for the regulation of common fragile site stability.
N. Howlett, T. Taniguchi, Sandra G. Durkin, A. D'Andrea +1 more
2005Human Molecular Genetics294 citations Open access
Semantic Scholar
Isolation and characterization of the faciogenital dysplasia (Aarskog-Scott syndrome) gene: a putative Rho/Rac guanine nucleotide exchange factor.
N. Pasteris, Amy B. Cadle, L. Logie, M. Porteous +5 more
1994Cell285 citations Open access
Semantic Scholar
Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition.
Michael W. Glynn, T. Glover
2005Human Molecular Genetics266 citations
Semantic Scholar
FRA3B extends over a broad region and contains a spontaneous HPV16 integration site: direct evidence for the coincidence of viral integration sites and fragile sites.
C. Wilke, B. Hall, Ann Hoge, W. Paradee +2 more
1996Human Molecular Genetics255 citations
Semantic Scholar
Replication of a common fragile site, FRA3B, occurs late in S phase and is delayed further upon induction: implications for the mechanism of fragile site induction.
M. L. Le Beau, F. Rassool, M. Neilly, R. Espinosa +3 more
1998Human Molecular Genetics248 citations
Semantic Scholar
Fragile Sites in Cancer: More Than Meets the Eye
T. Glover, T. E. Wilson, Martin F. Arlt
2017Nature Reviews. Cancer220 citations Open access
Semantic Scholar
Common fragile sites as targets for chromosome rearrangements.
Martin F. Arlt, Sandra G. Durkin, Ryan L. Ragland, T. Glover
2006DNA Repair214 citations
Semantic Scholar
Common fragile sites
Martin F. Arlt, A. Casper, T. Glover
2003Cytogenetic and Genome Research205 citations
Semantic Scholar
Isolation of a murine copper transporter gene, tissue specific expression and functional complementation of a yeast copper transport mutant.
Jaekwon Lee, J. Prohaska, S. Dagenais, T. Glover +1 more
2000Gene205 citations
Semantic Scholar
FOXC2 haploinsufficient mice are a model for human autosomal dominant lymphedema-distichiasis syndrome.
B. Kriederman, T. Myloyde, M. Witte, S. Dagenais +10 more
2003Human Molecular Genetics200 citations
Semantic Scholar
Isolation of human and murine homologues of the Drosophila minibrain gene: human homologue maps to 21q22.2 in the Down syndrome "critical region".
Woo-Joo Song, L. Sternberg, Carol Kasten-Sportes, M. Keuren +7 more
1996Genomics184 citations
Semantic Scholar
TP53 mutations are frequent in malignant NFI tumors
E. Legius, H. Dierick, Rina Wu, B. K. Hall +3 more
1994Genes, Chromosomes and Cancer181 citations
Semantic Scholar
Large transcription units unify copy number variants and common fragile sites arising under replication stress
T. E. Wilson, Martin F. Arlt, So Hae Park, Sountharia Rajendran +3 more
2015Genome Research177 citations Open access
Semantic Scholar
Genomic amplification of MET with boundaries within fragile site FRA7G and upregulation of MET pathways in esophageal adenocarcinoma
Charles T. Miller, Lin Lin, A. Casper, J. Lim +7 more
2006Oncogene175 citations Open access
Semantic Scholar
Mechanisms of common fragile site instability.
T. Glover, Martin F. Arlt, A. Casper, Sandra G. Durkin
2005Human Molecular Genetics161 citations Open access
Semantic Scholar
Replication stress induces genome-wide copy number changes in human cells that resemble polymorphic and pathogenic variants.
Martin F. Arlt, J. Mulle, Valerie Schaibley, Ryan L. Ragland +3 more
2009American Journal of Human Genetics148 citations Open access
Semantic Scholar
Depletion of CHK1, but not CHK2, induces chromosomal instability and breaks at common fragile sites
Sandra G. Durkin, Martin F. Arlt, N. Howlett, T. Glover
2006Oncogene142 citations Open access
Semantic Scholar
BRCA1 Is Required for Common-Fragile-Site Stability via Its G2/M Checkpoint Function
Martin F. Arlt, Bo Xu, Sandra G. Durkin, A. Casper +2 more
2004Molecular and Cellular Biology132 citations Open access
Semantic Scholar
Replication stress induces tumor-like microdeletions in FHIT/FRA3B
Sandra G. Durkin, Ryan L. Ragland, Martin F. Arlt, J. Mulle +2 more
2008Proceedings of the National Academy of Sciences of the United States of America128 citations Open access
Semantic Scholar
Replication Stress and Mechanisms of CNV Formation
Martin F. Arlt, T. E. Wilson, T. Glover
2012Current Opinion in Genetics and Development126 citations Open access
Semantic Scholar
Immunocytochemical Localization of the Menkes Copper Transport Protein (ATP7A) to the Trans-Golgi Network
H. Dierick, Ayla N. Adam, J. Escara-Wilke, T. Glover
1997Human Molecular Genetics125 citations Open access
Semantic Scholar
Mutations in the murine homologue of the Menkes gene in dappled and blotchy mice
J. Mercer, Andrew Grimes, L. Ambrosini, P. Lockhart +3 more
1994Nature Genetics125 citations Open access
Semantic Scholar
Frequent deletions of FHIT and FRA3B in Barrett's metaplasia and esophageal adenocarcinomas
Michael Dagmar, D. Beer, Charles W Wilke, Diane E. Miller +1 more
1997Oncogene122 citations Open access
Semantic Scholar
A translocation interrupts the COL5A1 gene in a patient with Ehlers–Danlos syndrome and hypomelanosis of Ito
H. Toriello, T. Glover, K. Takahara, P. Byers +3 more
1996Nature Genetics122 citations
Semantic Scholar
Distinct areas of allelic loss on chromosomal regions 10p and 10q in human prostate cancer.
Tanya M. Trybus, A. Burgess, K. Wojno, T. Glover +1 more
1996Cancer Research120 citations
Semantic Scholar
A Gata2 intronic enhancer confers its pan-endothelia-specific regulation
M. Khandekar, W. Brandt, Yinghui Zhou, S. Dagenais +6 more
2007Development109 citations
Semantic Scholar
Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome.
S. Dagenais, Rebecca L Hartsough, R. Erickson, M. Witte +2 more
2004Gene Expression Patterns107 citations
Semantic Scholar
Chromosomal instability at common fragile sites in Seckel syndrome.
A. Casper, Sandra G. Durkin, Martin F. Arlt, T. Glover
2004American Journal of Human Genetics106 citations Open access
Semantic Scholar
Clinical heterogeneity in lymphoedema-distichiasis withFOXC2 truncating mutations
R. Erickson, S. Dagenais, Mark S Caulder, C. Downs +8 more
2001Journal of Medical Genetics103 citations Open access
Semantic Scholar
The Hepatocyte Nuclear Factor 3 α Gene, HNF3α (FOXA1), on Chromosome Band 14q13 Is Amplified and Overexpressed in Esophageal and Lung Adenocarcinomas
Lin Lin, Charles T. Miller, Jorge I. Contreras, M. Prescott +8 more
2002102 citations
Semantic Scholar
The characterization of the common fragile site FRA16D and its involvement in multiple myeloma translocations.
Kurt A. Krummel, L. Roberts, M. Kawakami, T. Glover +1 more
2000Genomics102 citations
Semantic Scholar
Hydroxyurea induces de novo copy number variants in human cells
Martin F. Arlt, Alev Cagla Ozdemir, Shanda R. Birkeland, T. E. Wilson +1 more
2011Proceedings of the National Academy of Sciences of the United States of America96 citations Open access
Semantic Scholar
Deficiency of the cytoskeletal protein SPECC1L leads to oblique facial clefting.
I. Saadi, F. Alkuraya, Stephen S. Gisselbrecht, W. Goessling +14 more
2011American Journal of Human Genetics92 citations Open access
Semantic Scholar
The hepatocyte nuclear factor 3 alpha gene, HNF3alpha (FOXA1), on chromosome band 14q13 is amplified and overexpressed in esophageal and lung adenocarcinomas.
Lin Lin, Charles T. Miller, Jorge I. Contreras, M. Prescott +8 more
2002Cancer Research91 citations
Semantic Scholar
Activation of GATA binding protein 6 (GATA6) sustains oncogenic lineage-survival in esophageal adenocarcinoma
L. Lin, A. Bass, W. Lockwood, Z. Wang +11 more
2012Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Common fragile sites.
T. Glover
2006Cancer Letters86 citations
Semantic Scholar
The murine Fhit gene is highly similar to its human orthologue and maps to a common fragile site region.
T. Glover, Ann Hoge, Diane E. Miller, June E. Ascara-Wilke +5 more
1998Cancer Research68 citations
Semantic Scholar
Frequent breakpoints in the 3p14.2 fragile site, FRA3B, in pancreatic tumors.
Ravi Shridhar, V. Shridhar, Xiaohong Wang, W. Paradee +6 more
1996Cancer Research67 citations
Semantic Scholar
Functional Interaction between the Fanconi Anemia D2 Protein and Proliferating Cell Nuclear Antigen (PCNA) via a Conserved Putative PCNA Interaction Motif*
N. Howlett, Julie Harney, Meghan A. Rego, Frederick W. Kolling +1 more
2009Journal of Biological Chemistry66 citations Open access
Semantic Scholar
Instability at chromosomal fragile sites.
T. Glover
1998Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer65 citations
Semantic Scholar
Demethylation of repetitive DNA sequences in neuroblastoma
D. Thoraval, J. Asakawa, K. Wimmer, R. Kuick +5 more
1996Genes, Chromosomes and Cancer62 citations
Semantic Scholar
Amplification and overexpression of the dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 2 (DYRK2) gene in esophageal and lung adenocarcinomas.
Charles T. Miller, Sanjeev Aggarwal, T. K. Lin, S. Dagenais +5 more
2003Cancer Research59 citations
Semantic Scholar
De Novo CNV Formation in Mouse Embryonic Stem Cells Occurs in the Absence of Xrcc4-Dependent Nonhomologous End Joining
Martin F. Arlt, Sountharia Rajendran, Shanda R. Birkeland, T. E. Wilson +1 more
2012PLoS Genetics55 citations Open access
Semantic Scholar
A novel VEGFR3 mutation causes Milroy disease
M. G. Butler, S. Dagenais, S. Rockson, T. Glover
2007American Journal of Medical Genetics. Part A53 citations Open access
Semantic Scholar
A novel somatic mutation achieves partial rescue in a child with Hutchinson-Gilford progeria syndrome
D. Bar, Martin F. Arlt, Joan Brazier, W. Norris +7 more
2016Journal of Medical Genetics38 citations Open access
Semantic Scholar

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Martin F. Arlt — researcher profile on SciRah
S. Dagenais×11
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Sandra G. Durkin×10
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D. Beer×7
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T. E. Wilson×5

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Charles T. Miller — researcher profile on SciRah

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Lin Lin — researcher profile on SciRah