Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

Lisa M. Ooms · SciRah

Researcher profile · Semantic Scholar

Lisa M. Ooms

Share profile

Lisa M. Ooms — researcher profile on SciRah

h-index: 26
Works: 56
Citations: 3,061

Most-cited papers

Reactive oxygen species enhance insulin sensitivity
Kim Loh, Hai-Yang Deng, Atsushi Fukushima, Xiao-Chu Cai +15 more
2009Cell Metabolism582 citations Open access
Semantic Scholar
Inositol polyphosphate 4-phosphatase II regulates PI3K/Akt signaling and is lost in human basal-like breast cancers
C. Fedele, Lisa M. Ooms, Miriel S. H. Ho, J. Vieusseux +16 more
2010Proceedings of the National Academy of Sciences of the United States of America297 citations Open access
Semantic Scholar
The role of the inositol polyphosphate 5-phosphatases in cellular function and human disease.
Lisa M. Ooms, K. Horan, P. Rahman, G. Seaton +3 more
2009Biochemical Journal248 citations
Semantic Scholar
The SH2-containing inositol polyphosphate 5-phosphatase, SHIP-2, binds filamin and regulates submembraneous actin
Jennifer M. Dyson, C. O'Malley, Jelena Becanovic, A. Munday +5 more
2001Journal of Cell Biology171 citations Open access
Semantic Scholar
A New Family of 10 Murine Ovalbumin Serpins Includes Two Homologs of Proteinase Inhibitor 8 and Two Homologs of the Granzyme B Inhibitor (Proteinase Inhibitor 9)*
Jiu-Ru Sun, Lisa M. Ooms, C. Bird, V. Sutton +2 more
1997Journal of Biological Chemistry125 citations Open access
Semantic Scholar
The Inositol Polyphosphate 5-Phosphatase PIPP Regulates AKT1-Dependent Breast Cancer Growth and Metastasis.
Lisa M. Ooms, Lauren C. Binge, E. M. Davies, P. Rahman +13 more
2015Cancer Cell121 citations Open access
Semantic Scholar
Characterization of Two Isoforms of the Skeletal Muscle LIM Protein 1, SLIM1
S. Brown, Meagan J. McGrath, Lisa M. Ooms, R. Gurung +2 more
1999Journal of Biological Chemistry106 citations Open access
Semantic Scholar
Regulation of PI3K effector signalling in cancer by the phosphoinositide phosphatases
Samuel J. Rodgers, Daniel T. Ferguson, C. Mitchell, Lisa M. Ooms
2017Bioscience Reports105 citations Open access
Semantic Scholar
Identification of a Novel Domain in Two Mammalian Inositol-polyphosphate 5-Phosphatases That Mediates Membrane Ruffle Localization
R. Gurung, April Tan, Lisa M. Ooms, Meagan J. McGrath +5 more
2003Journal of Biological Chemistry99 citations Open access
Semantic Scholar
Cloning and Characterization of a 72-kDa Inositol-polyphosphate 5-Phosphatase Localized to the Golgi Network*
A. Kong, Caroline J. Speed, C. O'Malley, M. Layton +5 more
2000Journal of Biological Chemistry96 citations Open access
Semantic Scholar
The inositol polyphosphate 5-phosphatase, PIPP, Is a novel regulator of phosphoinositide 3-kinase-dependent neurite elongation.
Lisa M. Ooms, C. Fedele, M. V. Astle, Ivan. Ivetac +6 more
2005Molecular Biology of the Cell76 citations Open access
Semantic Scholar
The Inositol Polyphosphate 5-Phosphatases and the Apurinic/Apyrimidinic Base Excision Repair Endonucleases Share a Common Mechanism for Catalysis*
J. Whisstock, Susana Romero, R. Gurung, H. Nandurkar +3 more
2000Journal of Biological Chemistry76 citations Open access
Semantic Scholar
The Phosphatidylinositol (3,4,5)-Trisphosphate-dependent Rac Exchanger 1·Ras-related C3 Botulinum Toxin Substrate 1 (P-Rex1·Rac1) Complex Reveals the Basis of Rac1 Activation in Breast Cancer Cells*
Christina M. Lucato, M. Halls, Lisa M. Ooms, Heng-Jia Liu +3 more
2015Journal of Biological Chemistry65 citations Open access
Semantic Scholar
INPP4B promotes PI3Kα-dependent late endosome formation and Wnt/β-catenin signaling in breast cancer
Samuel J. Rodgers, Lisa M. Ooms, V. Oorschot, R. Schittenhelm +17 more
2021Nature Communications61 citations Open access
Semantic Scholar
The inositol polyphosphate 5-phosphatases: traffic controllers, waistline watchers and tumour suppressors?
M. V. Astle, K. Horan, Lisa M. Ooms, C. Mitchell
2007Biochemical Society Symposium59 citations
Semantic Scholar
Inositol polyphosphate 4-phosphatase II (INPP4B) is associated with chemoresistance and poor outcome in AML.
S. Rijal, S. Fleming, N. Cummings, Natalie K. Rynkiewicz +10 more
2015Blood57 citations Open access
Semantic Scholar
PTEN and Other PtdIns(3,4,5)P3 Lipid Phosphatases in Breast Cancer
M. Csolle, Lisa M. Ooms, A. Papa, C. Mitchell
2020International Journal of Molecular Sciences52 citations Open access
Semantic Scholar
Inositol Polyphosphate 5‐Phosphatases: Lipid Phosphatases With Flair
C. Mitchell, R. Gurung, A. Kong, Jennifer M. Dyson +2 more
2002IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology52 citations
Semantic Scholar
P-Rex1 – a multidomain protein that regulates neurite differentiation
Joanne E. Waters, M. V. Astle, Lisa M. Ooms, Demis Balamatsias +2 more
2008Journal of Cell Science51 citations Open access
Semantic Scholar
P-Rex1 and P-Rex2 RacGEFs and cancer.
Nuthasuda Srijakotre, Joey Man, Lisa M. Ooms, Christina M. Lucato +2 more
2017Biochemical Society Transactions45 citations Open access
Semantic Scholar
A Mutation in Synaptojanin 2 Causes Progressive Hearing Loss in the ENU-Mutagenised Mouse Strain Mozart
Shehnaaz S. M. Manji, Louise H. Williams, K. A. Miller, Lisa M. Ooms +3 more
2011PLoS ONE45 citations Open access
Semantic Scholar
The Yeast Inositol Polyphosphate 5-Phosphatases Inp52p and Inp53p Translocate to Actin Patches following Hyperosmotic Stress: Mechanism for Regulating Phosphatidylinositol 4,5-Bisphosphate at Plasma Membrane Invaginations
Lisa M. Ooms, Brad K. McColl, Fenny Wiradjaja, A. P. Wijayaratnam +4 more
2000Molecular and Cellular Biology42 citations Open access
Semantic Scholar
Tranexamic acid is an active site inhibitor of urokinase plasminogen activator.
Guo-Jie Wu, Blake A Mazzitelli, Adam J. Quek, Matthew J. Veldman +7 more
2019Blood Advances39 citations Open access
Semantic Scholar
The cardiac expression of striated muscle LIM protein 1 (SLIM1) is restricted to the outflow tract of the developing heart.
Susan Brown, C. Biben, Lisa M. Ooms, M. M. Maimone +4 more
1999Journal of Molecular and Cellular Cardiology35 citations
Semantic Scholar
INPP4B is highly expressed in prostate intermediate cells and its loss of expression in prostate carcinoma predicts for recurrence and poor long term survival
Natalie K. Rynkiewicz, C. Fedele, K. Chiam, Ruta Gupta +6 more
2015The Prostate31 citations Open access
Semantic Scholar
The Yeast Inositol Polyphosphate 5-Phosphatase Inp54p Localizes to the Endoplasmic Reticulum via a C-terminal Hydrophobic Anchoring Tail
Fenny Wiradjaja, Lisa M. Ooms, J. Whisstock, Brad K. McColl +4 more
2001Journal of Biological Chemistry28 citations Open access
Semantic Scholar
Differential SKIP expression in PTEN-deficient glioblastoma regulates cellular proliferation and migration
E. M. Davies, A. Kong, April Tan, R. Gurung +6 more
2014Oncogene27 citations Open access
Semantic Scholar
PtdIns(3,4,5)P3-dependent Rac Exchanger 1 (PREX1) Rac-Guanine Nucleotide Exchange Factor (GEF) Activity Promotes Breast Cancer Cell Proliferation and Tumor Growth via Activation of Extracellular Signal-regulated Kinase 1/2 (ERK1/2) Signaling*
Heng-Jia Liu, Lisa M. Ooms, Nuthasuda Srijakotre, Joey Man +7 more
2016Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Identification of a Proline-rich Inositol Polyphosphate 5-Phosphatase (PIPP)·Collapsin Response Mediator Protein 2 (CRMP2) Complex That Regulates Neurite Elongation*
M. V. Astle, Lisa M. Ooms, A. Cole, Lauren C. Binge +5 more
2011Journal of Biological Chemistry25 citations Open access
Semantic Scholar
Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging.
Alessia Floerchinger, K. Murphy, Sharissa L. Latham, Sean C. Warren +33 more
2021Cell Reports23 citations Open access
Semantic Scholar
Control of Glucocorticoid Receptor Levels by PTEN Establishes a Failsafe Mechanism for Tumor Suppression.
Hon Y. K. Yip, Annabel Chee, C. Ang, Sung-Young Shin +12 more
2020Molecules and Cells23 citations Open access
Semantic Scholar
AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease.
S. Conduit, E. M. Davies, Lisa M. Ooms, R. Gurung +6 more
2019Human Molecular Genetics23 citations Open access
Semantic Scholar
The Shc-binding site of the betac subunit of the GM-CSF/IL-3/IL-5 receptors is a negative regulator of hematopoiesis.
Hayley S. Ramshaw, M. Guthridge, F. Stomski, E. Barry +4 more
2007Blood22 citations Open access
Semantic Scholar
An ENU-induced mouse mutant of SHIP1 reveals a critical role of the stem cell isoform for suppression of macrophage activation.
N. Nguyen, M. Maxwell, Lisa M. Ooms, E. M. Davies +8 more
2011Blood20 citations Open access
Semantic Scholar
Silencer of Death Domains (SODD) Inhibits Skeletal Muscle and Kidney Enriched Inositol 5-Phosphatase (SKIP) and Regulates Phosphoinositide 3-Kinase (PI3K)/Akt Signaling to the Actin Cytoskeleton*
P. Rahman, Richard D Huysmans, Fenny Wiradjaja, R. Gurung +8 more
2011Journal of Biological Chemistry17 citations Open access
Semantic Scholar
The INPP4B paradox: Like PTEN, but different.
Sabryn A Hamila, Lisa M. Ooms, Samuel J. Rodgers, C. Mitchell
2021Advances in Biological Regulation16 citations
Semantic Scholar
PtdIns(3,4,5)P3-dependent Rac exchanger 1 (P-Rex1) promotes mammary tumor initiation and metastasis
Nuthasuda Srijakotre, Heng-Jia Liu, Max Nobis, Joey Man +10 more
2020Proceedings of the National Academy of Sciences of the United States of America16 citations Open access
Semantic Scholar
Inactivation of the Phosphoinositide Phosphatases Sac1p and Inp54p Leads to Accumulation of Phosphatidylinositol 4,5-Bisphosphate on Vacuole Membranes and Vacuolar Fusion Defects*
Fenny Wiradjaja, Lisa M. Ooms, S. Tahirovic, Ellie Kuhne +5 more
2007Journal of Biological Chemistry15 citations Open access
Semantic Scholar
The mechanisms of class 1A PI3K and Wnt/β-catenin coupled signaling in breast cancer
Samuel J. Rodgers, C. Mitchell, Lisa M. Ooms
2023Biochemical Society Transactions11 citations Open access
Semantic Scholar
Functional and Phenotypic Characterisations of Common Syngeneic Tumour Cell Lines as Estrogen Receptor-Positive Breast Cancer Models
M. Lambouras, Charlotte Roelofs, Melrine Pereira, Emily Gruber +9 more
2023International Journal of Molecular Sciences8 citations Open access
Semantic Scholar
The FDA-Approved Drug Pyrvinium Selectively Targets ER+ Breast Cancer Cells with High INPP4B Expression
Samuel J. Rodgers, Lisa M. Ooms, C. Mitchell
2022Cancers7 citations Open access
Semantic Scholar
Analysis of phosphatidylinositol 3,4,5 trisphosphate 5-phosphatase activity by in vitro and in vivo assays.
Lisa M. Ooms, Jennifer M. Dyson, A. Kong, C. Mitchell
2009Methods in molecular biology7 citations
Semantic Scholar
Phosphoinositide phosphatases: Modifiers of phosphoinositide signaling in health and disease.
E. M. Davies, Emily I. Jones, Lisa M. Ooms, R. Gurung +2 more
2025Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids5 citations Open access
Semantic Scholar
&bgr;-catenin ablation exacerbates polycystic kidney disease progression
S. Conduit, Sandra Hakim, S. J. Feeney, Lisa M. Ooms +3 more
2018Human Molecular Genetics5 citations Open access
Semantic Scholar
Human Gene Mapping Report: Proteinase inhibitor 8 Map position 18q21.3
Fiona L. Scott, H. Eyre, Lisa M. Ooms, Jiu-Ru Sun +2 more
1997Chromosome Research3 citations
Semantic Scholar
Non-redundant roles of the phosphoinositide phosphatases PTEN and PIPP in PI3K/AKT signaling in breast cancer
Lisa M. Ooms, Daniel T. Ferguson, Samuel J. Rodgers, Karmanpreet K Sukhija +8 more
2025Communications Biology2 citations Open access
Semantic Scholar
The power of five - inositol polyphosphate 5-phosphatase gene mutations at the intersection of development and disease.
Meagan J. McGrath, E. M. Davies, Lisa M. Ooms, Randini Nanayakkara +3 more
2025FEBS Letters2 citations Open access
Semantic Scholar
A late endosome signaling hub that couples PI3Kα and WNT/β-catenin signaling in breast cancer
Samuel J. Rodgers, Sabryn A Hamila, C. Mitchell, Lisa M. Ooms
2021Molecular & Cellular Oncology2 citations Open access
Semantic Scholar
Endocrine therapy reprogramming of breast cancer facilitates metastatic escape via upregulation of P-Rex1/Rac1 signalling
Kristine J. Fernandez, Ghazal Sultani, Max Nobis, B. Gloss +31 more
2026Nature Communications1 citations Open access
Semantic Scholar
PREX1 regulates ERK1/2 in breast cancer
Heng-Jia Liu, Lisa M. Ooms, Nuthasuda Srijakotre, Joey Man +9 more
20171 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

C. Mitchell×40
Invite
C. Mitchell — researcher profile on SciRah
R. Gurung×15
Invite
R. Gurung — researcher profile on SciRah
T. Tiganis×7
Invite
T. Tiganis — researcher profile on SciRah
Jennifer M. Dyson×7
Invite
Jennifer M. Dyson — researcher profile on SciRah

Samuel J. Rodgers

×7

Invite

Samuel J. Rodgers — researcher profile on SciRah

E. M. Davies×6

Invite

E. M. Davies — researcher profile on SciRah

Invite

A. Papa — researcher profile on SciRah

Meagan J. McGrath×6

Invite

Meagan J. McGrath — researcher profile on SciRah

Invite

C. Fedele — researcher profile on SciRah

J. Vieusseux×5

Invite

J. Vieusseux — researcher profile on SciRah

Invite

C. Mclean — researcher profile on SciRah

J. Whisstock×5

Invite

J. Whisstock — researcher profile on SciRah