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Kristen K. Skarratt · SciRah

Researcher profile · Semantic Scholar

Kristen K. Skarratt

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Kristen K. Skarratt — researcher profile on SciRah

h-index: 19
Works: 42
Citations: 1,869

Most-cited papers

IL-10 Potentiates Differentiation of Human Induced Regulatory T Cells via STAT3 and Foxo1
P. Hsu, B. Santner‐Nanan, Ming-Jing Hu, Kristen K. Skarratt +5 more
2015Journal of Immunology280 citations
Semantic Scholar
A polymorphism in the P2X7 gene increases susceptibility to extrapulmonary tuberculosis.
S. Fernando, B. Saunders, R. Sluyter, Kristen K. Skarratt +4 more
2007American Journal of Respiratory and Critical Care Medicine218 citations
Semantic Scholar
A Thr357 to Ser Polymorphism in Homozygous and Compound Heterozygous Subjects Causes Absent or Reduced P2X7 Function and Impairs ATP-induced Mycobacterial Killing by Macrophages*
Anne N. Shemon, R. Sluyter, S. Fernando, Alison L. Clarke +9 more
2006Journal of Biological Chemistry183 citations Open access
Semantic Scholar
Two haplotypes of the P2X7 receptor containing the Ala‐348 to Thr polymorphism exhibit a gain‐of‐function effect and enhanced interleukin‐1β secretion
L. Stokes, S. Fuller, R. Sluyter, Kristen K. Skarratt +2 more
2010The FASEB Journal170 citations Open access
Semantic Scholar
An Arg307 to Gln Polymorphism within the ATP-binding Site Causes Loss of Function of the Human P2X7 Receptor*
B. Gu, R. Sluyter, Kristen K. Skarratt, Anne N. Shemon +6 more
2004Journal of Biological Chemistry159 citations Open access
Semantic Scholar
Genetics of the P2X7 receptor and human disease
S. Fuller, L. Stokes, Kristen K. Skarratt, B. Gu +1 more
2009Purinergic Signalling Purinergic Signalling129 citations Open access
Semantic Scholar
Probenecid Blocks Human P2X7 Receptor-Induced Dye Uptake via a Pannexin-1 Independent Mechanism
A. Bhaskaracharya, Phuong Dao-Ung, I. Jalilian, Mari Spildrejorde +4 more
2014PLoS ONE82 citations Open access
Semantic Scholar
Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women
A. Gartland, Kristen K. Skarratt, L. Hocking, Claire Parsons +6 more
2012European Journal of Human Genetics81 citations Open access
Semantic Scholar
Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures
N. Jørgensen, L. Husted, Kristen K. Skarratt, L. Stokes +11 more
2012European Journal of Human Genetics81 citations Open access
Semantic Scholar
Gene dosage determines the negative effects of polymorphic alleles of the P2X7 receptor on adenosine triphosphate-mediated killing of mycobacteria by human macrophages.
S. Fernando, B. Saunders, R. Sluyter, Kristen K. Skarratt +2 more
2005Journal of Infectious Diseases71 citations Open access
Semantic Scholar
Human epidermal and monocyte-derived langerhans cells express functional P2X receptors.
J. G. Georgiou, Kristen K. Skarratt, S. Fuller, Christopher J. Martin +3 more
2005Journal of Investigative Dermatology61 citations Open access
Semantic Scholar
A Loss-of-Function Polymorphism in the Human P2X4 Receptor Is Associated With Increased Pulse Pressure
L. Stokes, K. Scurrah, J. Ellis, B. Cromer +4 more
2011HYPERTENSION59 citations
Semantic Scholar
Pharmacological Evaluation of Novel Bioisosteres of an Adamantanyl Benzamide P2X7 Receptor Antagonist.
Shane M. Wilkinson, Melissa L. Barron, James O'Brien-Brown, B. Janssen +10 more
2017ACS Chemical Neuroscience49 citations Open access
Semantic Scholar
Alternatively Spliced Isoforms of the P2X7 Receptor: Structure, Function and Disease Associations
Sophie K. F. De Salis, Lanxin Li, Zheng Chen, Kam-Wa Lam +3 more
2022International Journal of Molecular Sciences29 citations Open access
Semantic Scholar
Paroxetine suppresses recombinant human P2X7 responses
Phuong Dao-Ung, Kristen K. Skarratt, S. Fuller, L. Stokes
2015Purinergic Signalling Purinergic Signalling26 citations Open access
Semantic Scholar
Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome
S. Lester, L. Stokes, Kristen K. Skarratt, B. Gu +4 more
2013Arthritis Research & Therapy26 citations Open access
Semantic Scholar
An Arg 307 to Gln Polymorphism within the ATP-binding Site Causes Loss of Function of the Human P 2 X 7 Receptor *
B. Gu, R. Sluyter, Kristen K. Skarratt, Anne N. Shemon +6 more
200425 citations
Semantic Scholar
Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs
J. Thoms, Feng Yan, Henry R. Hampton, S. Davidson +52 more
2025Nature Communications20 citations Open access
Semantic Scholar
R270C polymorphism leads to loss of function of the canine P2X7 receptor.
Mari Spildrejorde, R. Bartlett, L. Stokes, I. Jalilian +10 more
2014Physiological Genomics20 citations Open access
Semantic Scholar
Functional significance of P2RX7 polymorphisms associated with affective mood disorders.
R. Sluyter, L. Stokes, S. Fuller, Kristen K. Skarratt +2 more
2010Journal of Psychiatric Research19 citations
Semantic Scholar
The Effect of Antidepressants on Mesenchymal Stem Cell Differentiation
Jeff S. Kruk, Sandra Bermeo, Kristen K. Skarratt, S. Fuller +1 more
2018Journal of Bone Metabolism13 citations Open access
Semantic Scholar
Genetic Variations in the P2X7 Receptor: Opportunities and Challenges for Drug Development
Justin S. Y. Cheah, Kristen K. Skarratt, Stephen J. Fuller, Thomas Balle
2025International Journal of Molecular Sciences10 citations
Semantic Scholar
Loss-of-function/gain-of-function polymorphisms of the ATP sensitive P2X7R influence sepsis, septic shock, pneumonia, and survival outcomes
Johanna Guggemos, Stephen J. Fuller, Kristen K. Skarratt, Benjamin Mayer +1 more
2024Frontiers in Immunology10 citations
Semantic Scholar
Immunophenotyping of Peripheral Blood Mononuclear Cells in Septic Shock Patients With High-Dimensional Flow Cytometry Analysis Reveals Two Subgroups With Differential Responses to Immunostimulant Drugs
Ya Wang, B. Gloss, B. Tang, S. Dervish +12 more
2021Frontiers in Immunology10 citations Open access
Semantic Scholar
Polymorphisms in the P 2 X 7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women
Alison Gartland, Kristen K. Skarratt, L. Hocking, Claire Parsons +6 more
20149 citations
Semantic Scholar
Quantitative real-time PCR eliminates false-positives in colony screening PCR.
Kristen K. Skarratt, S. Fuller
2014Journal of Microbiological Methods7 citations
Semantic Scholar
Identification of the promoter region of the P2RX4 gene
B. Gu, Chun Sun, Valentina A. Valova, Kristen K. Skarratt +1 more
2010Molecular Biology Reports7 citations
Semantic Scholar
Combination of High-Resolution Structures for the B Cell Receptor and Co-Receptors Provides an Understanding of Their Interactions with Therapeutic Antibodies
Puja Bhattacharyya, R. Christopherson, Kristen K. Skarratt, J. Z. Chen +2 more
2023Cancers5 citations Open access
Semantic Scholar
R 270 C polymorphism leads to loss of function of the canine P 2 X 7 receptor
Mari Spildrejorde, R. Bartlett, L. Stokes, I. Jalilian +10 more
20144 citations
Semantic Scholar
PB1796: ADMINISTRATION OF A KETOGENIC DIET FOR CHEMOTHERAPY PROTECTION IN ACUTE LEUKEMIA PATIENTS: IS IT FEASIBLE, SAFE, AND VALUABLE? PRELIMINARY RESULTS OF THE RANDOMIZED CONTROLLED TRIAL LEU-KETO STUDY.
M. L. Cagigas, Gayathiri Rajakumar, Kristen K. Skarratt, Rachael Hayward +5 more
2023HemaSphere3 citations Open access
Semantic Scholar
Deep learning structural insights into heterotrimeric alternatively spliced P2X7 receptors
Sophie K. F. De Salis, J. Z. Chen, Kristen K. Skarratt, Stephen J. Fuller +1 more
2023Purinergic Signalling Purinergic Signalling3 citations Open access
Semantic Scholar
James Saville Wiley (1936–2022): pioneer of purinergic research in Australia and abroad
B. Gu, S. Fuller, Kristen K. Skarratt, L. Stokes +2 more
2023Purinergic Signalling Purinergic Signalling2 citations Open access
Semantic Scholar
Differential Levels of mRNAs in Normal B Lymphocytes, Monoclonal B Lymphocytosis and Chronic Lymphocytic Leukemia Cells from the Same Family Identify Susceptibility Genes
A. Alshahrani, Kristen K. Skarratt, K. Robledo, M. Hassanvand +2 more
2021Oncology and Therapy1 citations Open access
Semantic Scholar
The P2X7 receptor: insights from the murine monoclonal antibody clone L4
R. Sluyter, Amal Elhage, R. Bartlett, Debbie Watson +4 more
2026Purinergic Signalling Purinergic Signalling0 citations Open access
Semantic Scholar
Clinical Response to Azacitidine in Myelodysplastic Neoplasms is Associated with Distinct DNA Methylation Changes in Haematopoietic Stem and Progenitor cells in vivo
J. Thoms, Feng Yan, Henry R. Hampton, S. Davidson +52 more
2024medRxiv0 citations Open access
Semantic Scholar
Method for B Cell Receptor Enrichment in Malignant B Cells
Puja Bhattacharyya, Richard I. Christopherson, Kristen K. Skarratt, Stephen J. Fuller
2024Cancers0 citations Open access
Semantic Scholar
3178 – LONGITUDINAL DRUG INCORPORATION, CLONAL COMPOSITION, AND DNA METHYLATION DYNAMICS IN MDS/CMML PATIENTS TREATED WITH AZA
J. Thoms, Henry R. Hampton, Feng Yan, S. Davidson +48 more
2024Experimental Hematology0 citations Open access
Semantic Scholar
Structural insights into the heterotrimeric alternatively spliced P2X7 receptors
Sophie K. F. De Salis, J. Z. Chen, Kristen K. Skarratt, S. Fuller +1 more
2023bioRxiv0 citations Open access
Semantic Scholar
Design of concatenated ion channels using AlphaFold2: A new era?
Zheng Chen, Kristen K. Skarratt, Stephen J. Fuller, Kam-Wa Lam +1 more
2023Biophysical Journal0 citations Open access
Semantic Scholar
In Vivo Drug Incorporation and Intracellular Dynamics of Injectable Versus Oral Azacytidine: A Phase II Open Label Multicentre Trial
J. Pimanda, J. Thoms, Henry R. Hampton, S. Davidson +39 more
2022Blood0 citations Open access
Semantic Scholar
RX 7 single nucleotide polymorphism haplotype promotes exon 7 and 8 skipping , which is predicted to disrupt the P 2 X 7 receptor ATP-binding site
Kristen K. Skarratt, B. Gu, M. Lovelace, C. Milligan +5 more
20200 citations
Semantic Scholar
A missense variant leads to loss of function of the canine P2X7 receptor
R. Sluyter, Mari Spildrejorde, R. Bartlett, I. Jalilian +10 more
20140 citations
Semantic Scholar

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L. Stokes×16
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R. Sluyter×14
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J. Wiley×13
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