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Chastity L. Healy · SciRah

Researcher profile · Semantic Scholar

Chastity L. Healy

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Chastity L. Healy — researcher profile on SciRah

h-index: 11
Works: 32
Citations: 541

Most-cited papers

ω-3 fatty acids prevent pressure overload-induced cardiac fibrosis through activation of cGMP/PKG signaling in cardiac fibroblasts
Jing-Hai Chen, G. Shearer, Quanhai Chen, Chastity L. Healy +6 more
2011Circulation157 citations Open access
Semantic Scholar
Nuclear α1-Adrenergic Receptors Signal Activated ERK Localization to Caveolae in Adult Cardiac Myocytes
Casey D. Wright, Quanhai Chen, Nichole L. Baye, Yuan Huang +3 more
2008Circulation Research106 citations Open access
Semantic Scholar
EPA, not DHA, prevents fibrosis in pressure overload-induced heart failure: potential role of free fatty acid receptor 4[S]
Julie A. Eclov, Q. Qian, Rebecca A. Redetzke, Quanhai Chen +6 more
2015Journal of Lipid Research53 citations Open access
Semantic Scholar
Nuclear Localization of α1A‐Adrenergic Receptors Is Required for Signaling in Cardiac Myocytes: An “Inside‐Out” α1‐AR Signaling Pathway
Steven C. Wu, Erika F. Dahl, Casey D. Wright, Andrew L. Cypher +2 more
2014Journal of the American Heart Association : Cardiovascular and Cerebrovascular Disease35 citations Open access
Semantic Scholar
An Association Between Gene Expression and Better Survival in Female Mice Following Myocardial Infarction
Quanhai Chen, Roy M. Williams, Chastity L. Healy, Casey D. Wright +2 more
2010Journal of Molecular and Cellular Cardiology34 citations Open access
Semantic Scholar
Loss of DNA repair mechanisms in cardiac myocytes induce dilated cardiomyopathy
Chathurika Henpita, Rajesh Vyas, Chastity L. Healy, Tra L. Kieu +26 more
2023Aging Cell27 citations Open access
Semantic Scholar
Free fatty acid receptor 4 responds to endogenous fatty acids to protect the heart from pressure overload.
Katherine A. Murphy, B. Harsch, Chastity L. Healy, Sonal S. Joshi +12 more
2021Cardiovascular Research27 citations Open access
Semantic Scholar
Subcellular compartmentalization of proximal Gαq-receptor signaling produces unique hypertrophic phenotypes in adult cardiac myocytes
Erika F. Dahl, Steven C. Wu, Chastity L. Healy, B. Harsch +2 more
2018Journal of Biological Chemistry21 citations Open access
Semantic Scholar
GATA4 is a survival factor in adult cardiac myocytes but is not required for alpha1A-adrenergic receptor survival signaling.
Yuan Huang, Casey D. Wright, Satoru Kobayashi, Chastity L. Healy +4 more
2008American Journal of Physiology. Heart and Circulatory Physiology16 citations Open access
Semantic Scholar
Atrial myopathy quantified by speckle-tracking echocardiography in mice
Michael J. Zhang, Dylan J. Gyberg, Chastity L. Healy, Naixin Zhang +3 more
2023Circulation Cardiovascular Imaging15 citations
Semantic Scholar
FFAR4 regulates cardiac oxylipin balance to promote inflammation resolution in HFpEF secondary to metabolic syndrome
Naixin Zhang, B. Harsch, Michael J. Zhang, Dylan J. Gyberg +11 more
2023Journal of Lipid Research11 citations Open access
Semantic Scholar
ERK mediated survival signaling is dependent on the Gq-G-protein coupled receptor type and subcellular localization in adult cardiac myocytes.
Erika F. Dahl, Steven C. Wu, Chastity L. Healy, J. Perry +1 more
2019Journal of Molecular and Cellular Cardiology11 citations
Semantic Scholar
Guanylyl cyclase-A phosphorylation decreases cardiac hypertrophy and improves systolic function in male, but not female, mice
Brandon M. Wagner, J. Robinson, Chastity L. Healy, Madeline M. Gauthier +5 more
2021The FASEB Journal8 citations Open access
Semantic Scholar
Signaling through free fatty acid receptor 4 attenuates cardiometabolic disease.
T. O'Connell, Katherine A. Murphy, Naixin Zhang, Sara J. Puccini +4 more
2022Physiology6 citations Open access
Semantic Scholar
RBFOX1 Regulates Calcium Signaling and Enhances SERCA2 Translation
Sadiq Umar, Wu-Qiang Zhu, F. Souza-Neto, Ingrid K. Bender +4 more
2025Cells3 citations Open access
Semantic Scholar
Murine Ischemia Reperfusion Without Endotracheal Intubation or Ventilation
Michael J Zhang, Sergey Karachenets, Chastity L. Healy, T. O'Connell
2021JACC: Basic to Translational Science3 citations Open access
Semantic Scholar
Free fatty acid receptor 4 in cardiac myocytes ameliorates ischemic cardiomyopathy
Michael J. Zhang, Sergey Karachenets, Dylan J. Gyberg, Sara J. Puccini +4 more
2024bioRxiv2 citations Open access
Semantic Scholar
Epitope-tagged and phosphomimetic mouse models for investigating natriuretic peptide-stimulated receptor guanylyl cyclases
J. Egbert, Tracy F. Uliasz, K. Lowther, D. Kaback +6 more
2022Frontiers in Molecular Neuroscience2 citations Open access
Semantic Scholar
Free fatty acid receptor 4 is a nutrient sensor that resolves inflammation to maintain cardiac homeostasis
Katherine A. Murphy, B. Harsch, Chastity L. Healy, Sonal S. Joshi +11 more
2019bioRxiv1 citations Open access
Semantic Scholar
P21 activated kinase 1 (PAK1) protects heart from pressure overload induced pathological cardiac remodeling
K. Mao, Chastity L. Healy, D. Timm, Satoru Kobayashi +5 more
20091 citations
Semantic Scholar
Free fatty acid receptor 4 in cardiac myocytes ameliorates ischemic cardiomyopathy.
Michael J. Zhang, Sara J. Puccini, Sergey Karachenets, Dylan J. Gyberg +11 more
2026Cardiovascular Research0 citations Open access
Semantic Scholar
Mechanistic Basis of EPA Cardioprotective Signaling in Cardiac Myocytes: Ffar4-ChemR23 Signaling (Abstract ID: 233536)
Sara J. Puccini, B. Harsch, Mallika Malaviya, Chastity L. Healy +4 more
2026Journal of Pharmacology and Experimental Therapeutics0 citations
Semantic Scholar
Targeting GPR120 to Regulate Lipid Mediators of Inflammation in Alzheimer's Disease (Abstract ID: 229812)
Katherine A Murphy, B. Harsch, Sara J. Puccini, Chastity L. Healy +3 more
2026Journal of Pharmacology and Experimental Therapeutics0 citations
Semantic Scholar
A Cell Autonomous Free fatty acid receptor 4 - ChemR23 Signaling Cascade Protects Cardiac Myocytes from Ischemic Injury
Sara J. Puccini, Chastity L. Healy, B. Harsch, Ahmed Ahmed +2 more
2025bioRxiv0 citations Open access
Semantic Scholar
Abstract P319: Eliminating Cardiotoxicity In Alpha1-adrenergic Receptor Antagonists
Chastity L. Healy, Sara J. Puccini, Ingrid R. Aragon, Vasudeva Dodda +3 more
2023HYPERTENSION0 citations
Semantic Scholar
Free fatty acid receptor 4 (FFAR4) regulates cardiac oxylipin balance to promote inflammation resolution in a model of heart failure preserved ejection fraction secondary to metabolic syndrome
Naixin Zhang, Katherine A. Murphy, B. Harsch, Michael J. Zhang +9 more
2022bioRxiv0 citations Open access
Semantic Scholar
Bimolecular modeling and simulation of antagonist binding to the alpha‐1A adrenergic receptor
Timothy D. O'Connell, Ingrid R. Aragon, Chastity L. Healy, R. Muthyala +1 more
2019The FASEB Journal0 citations
Semantic Scholar
Abstract 255: Novel Role for Free Fatty Acid Receptor 4 in Response to Pathologic Pressure Overload-Induced Heart Failure in Mice
Katherine A. Murphy, Sonal S. Joshi, Chastity L. Healy, Katherine M. Ernste +6 more
2019Circulation Research0 citations
Semantic Scholar
Abstract 526: Free Fatty Acid Receptor 4 is Required for an Adaptive Response to Pathologic Pressure Overload-induced Heart Failure in Mice
Sonal S. Joshi, Chastity L. Healy, Brandon M. Wagner, T. O'Connell
2018Circulation Research0 citations
Semantic Scholar
030Compartmentalized Gαq-Signaling in Adult Cardiac Myocytes
Erika F. Dahl, Steven C. Wu, Chastity L. Healy, T. O'Connell
20170 citations
Semantic Scholar
α1A‐adrenergic receptor is required for normal prostate development and successful conception in mice
Chastity L. Healy, Casey D. Wright, T. O'Connell
20120 citations
Semantic Scholar
Abstract P193: Nuclear Localization of the α1B-Adrenergic Receptor Subtype Is Required for Hypertrophic Signaling in Cardiac Myocytes
Steven C. Wu, Andrew L. Cypher, Chastity L. Healy, Casey D. Wright +2 more
20110 citations
Semantic Scholar

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T. O'Connell×21
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T. O'Connell — researcher profile on SciRah
B. Harsch×11
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B. Harsch — researcher profile on SciRah
Steven C. Wu×10
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G. Shearer×9
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Casey D. Wright

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Casey D. Wright — researcher profile on SciRah

Brandon M. Wagner×8

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Timothy D. O'Connell×8

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Sara J. Puccini×7

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Katherine A. Murphy×6

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Michael J. Zhang×6

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Michael J. Zhang — researcher profile on SciRah

Dylan J. Gyberg×5

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Dylan J. Gyberg — researcher profile on SciRah

Quanhai Chen×4

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Quanhai Chen — researcher profile on SciRah