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K. Keefer · SciRah

Researcher profile · Semantic Scholar

K. Keefer

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K. Keefer — researcher profile on SciRah

h-index: 18
Works: 28
Citations: 942

Most-cited papers

A Splice Variant of the Human Ion Channel TRPM2 Modulates Neuroblastoma Tumor Growth through Hypoxia-inducible Factor (HIF)-1/2α*
Shu-Jen Chen, N. Hoffman, S. Shanmughapriya, L. Bao +19 more
2014Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Hyaluronan induces scarless repair in mouse limb organ culture.
Joseph A. Iocono, H. Ehrlich, K. Keefer, T. Krummel
1998Journal of Pediatric Surgery86 citations
Semantic Scholar
The second member of transient receptor potential-melastatin channel family protects hearts from ischemia-reperfusion injury.
B. Miller, Jufang Wang, Iwona Hirschler-Laszkiewicz, E. Gao +11 more
2013American Journal of Physiology. Heart and Circulatory Physiology81 citations Open access
Semantic Scholar
Vanadate and the absence of myofibroblasts in wound contraction.
H. Ehrlich, K. Keefer, Roland L. Myers, Antonio Passaniti
1999Archives of Surgery74 citations
Semantic Scholar
Transient receptor potential ion channel TRPM2 promotes AML proliferation and survival through modulation of mitochondrial function, ROS, and autophagy
Shu-Jen Chen, L. Bao, K. Keefer, S. Shanmughapriya +13 more
2020Cell Death and Disease62 citations Open access
Semantic Scholar
Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics*
L. Bao, Shu-Jen Chen, K. Conrad, K. Keefer +11 more
2016Journal of Biological Chemistry62 citations Open access
Semantic Scholar
Dexamethasone abrogates the fibrogenic effect of transforming growth factor-beta in rat granuloma and granulation tissue fibroblasts.
N. Meisler, K. Keefer, H. Ehrlich, D. Yager +2 more
1997Journal of Investigative Dermatology56 citations Open access
Semantic Scholar
Repeated additions of hyaluronan alters granulation tissue deposition in sponge implants in mice
Joseph A. Iocono, T. Krummel, K. Keefer, G. Allison +1 more
1998Wound Repair and Regeneration51 citations
Semantic Scholar
The human ion channel TRPM2 modulates neuroblastoma cell survival and mitochondrial function through Pyk2, CREB, and MCU activation
Iwona Hirschler-Laszkiewicz, Shu-Jen Chen, L. Bao, Jufang Wang +6 more
2018American Journal of Physiology - Cell Physiology48 citations Open access
Semantic Scholar
Regional Cerebral and Neural Lobe Blood Flow during Insulin-Induced Hypoglycemia in Unanesthetized Rats
R. Bryan, Bryan R. Hollinger, K. Keefer, R. B. Page
1987Journal of Cerebral Blood Flow and Metabolism42 citations Open access
Semantic Scholar
Regional Cerebral Glucose Utilization During Insulin‐Induced Hypoglycemia in Unanesthetized Rats
R. Bryan, K. Keefer, C. Macneill
1986Journal of Neurochemistry35 citations
Semantic Scholar
The Human Transient Receptor Potential Melastatin 2 Ion Channel Modulates ROS Through Nrf2
L. Bao, Fernanda Festa, Christopher S. Freet, John P Lee +7 more
2019Scientific Reports31 citations Open access
Semantic Scholar
The role of transforming growth factor‐β in the conversion from “scarless” healing to healing with scar formation
P. Houghton, K. Keefer, T. M. Krummel
1995Wound Repair and Regeneration28 citations
Semantic Scholar
The extracellular matrix of the fetal wound: hyaluronic acid controls lymphocyte adhesion.
Peter W. Dillon, K. Keefer, James H. Blackburn, P. Houghton +1 more
1994Journal of Surgical Research27 citations Open access
Semantic Scholar
The Transient Receptor Potential (TRP) Channel TRPC3 TRP Domain and AMP-activated Protein Kinase Binding Site Are Required for TRPC3 Activation by Erythropoietin*
Iwona Hirschler-Laszkiewicz, Qin Tong, K. Waybill, K. Conrad +5 more
2011Journal of Biological Chemistry26 citations Open access
Semantic Scholar
Vanadate ingestion increases the gain in wound breaking strength and leads to better organized collagen fibers in rats during healing.
H. Ehrlich, K. Keefer, George O. Maish, Roland L. Myers +1 more
2001Plastic and Reconstructive Surgery25 citations
Semantic Scholar
Mouse skin chemical carcinogenesis is inhibited by antizyme in promotion‐sensitive and promotion‐resistant genetic backgrounds
D. Feith, L. Shantz, Paula L. Shoop, K. Keefer +2 more
2007Molecular Carcinogenesis22 citations
Semantic Scholar
Overproduction of cardiac S-adenosylmethionine decarboxylase in transgenic mice.
Oleg Nisenberg, A. Pegg, P. Welsh, K. Keefer +1 more
2006Biochemical Journal22 citations Open access
Semantic Scholar
Trpc2 Depletion Protects RBC from Oxidative Stress-Induced Hemolysis
Iwona Hirschler-Laszkiewicz, Wenyi Zhang, K. Keefer, K. Conrad +5 more
2011Experimental Hematology18 citations Open access
Semantic Scholar
A simple method to assess the relative amount of collagen deposition in wounded fetal mouse limbs
P. Houghton, K. Keefer, R. Diegelmann, T. M. Krummel
1996Wound Repair and Regeneration16 citations
Semantic Scholar
The human ion channel TRPM2 modulates cell survival in neuroblastoma through E2F1 and FOXM1
Iwona Hirschler-Laszkiewicz, Fernanda Festa, Suming Huang, George-Lucian Moldovan +8 more
2022Scientific Reports14 citations Open access
Semantic Scholar
A New Assay to Screen for Head and Neck Squamous cell Carcinoma Using the Tumor Marker Metallopanstimulin
Wha-Joon Lee, K. Keefer, Christopher S. Hollenbeak, Brendan C. Stack
2004Otolaryngology Head & Neck Surgery12 citations
Semantic Scholar
The human ion channel TRPM2 modulates migration and invasion in neuroblastoma through regulation of integrin expression
L. Bao, Fernanda Festa, Iwona Hirschler-Laszkiewicz, K. Keefer +3 more
2022Scientific Reports10 citations Open access
Semantic Scholar
Abstract 1324: TRPM2 promotes leukemia proliferation and survival through modulation of ROS and autophagy
Shu-Jen Chen, L. Bao, K. Keefer, Longgui Chen +8 more
2018Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
Abstract 1458: TRPM2 modulates neuroblastoma cell survival through Pyk2, CREB and MCU activation
Iwona Hirschler-Laszkiewicz, Shu-Jen Chen, L. Bao, Jufang Wang +6 more
2018Molecular and Cellular Biology / Genetics0 citations
Semantic Scholar
TRPM2 Channels Protect Hearts from Ischemia-Reperfusion Injury
Joseph Y. Cheung, Jufang Wang, E. Gao, Jianliang Song +9 more
20130 citations Open access
Semantic Scholar
Abstract 1089: Two nonselective calcium channels, TRPC3 and TRPC6, play roles in erythropoietin signaling
Iwona Hirschler-Laszkiewicz, Qin Tong, K. Conrad, Wenyi Zhang +4 more
20110 citations
Semantic Scholar
9:40 am A New Assay to Detect Head and Neck Squamous Cell Carcinoma Using MPS
D. Chepeha, Terry TerryDay, T. Teknos, Brian F. Worden +5 more
2003Otolaryngology Head & Neck Surgery0 citations
Semantic Scholar

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