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O. Grauer · SciRah

Researcher profile · Semantic Scholar

O. Grauer

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O. Grauer — researcher profile on SciRah

h-index: 35
Works: 112
Citations: 5,186

Most-cited papers

Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA-09): a randomised, open-label, phase 3 trial.
U. Herrlinger, T. Tzaridis, F. Mack, J. Steinbach +44 more
2019The Lancet424 citations Open access
Semantic Scholar
Regulatory T cells and the PD-L1/PD-1 pathway mediate immune suppression in malignant human brain tumors.
J. Jacobs, A. Idema, K. Bol, S. Nierkens +6 more
2009Neuro-Oncology239 citations Open access
Semantic Scholar
CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo
O. Grauer, S. Nierkens, E. Bennink, Liza W. J. Toonen +4 more
2007International Journal of Cancer236 citations Open access
Semantic Scholar
Toll-like receptors on regulatory T cells: expanding immune regulation.
Roger P. M. Sutmuller, M. E. Morgan, M. Netea, O. Grauer +1 more
2006Trends in immunology214 citations
Semantic Scholar
Neurological manifestations of chronic graft-versus-host disease after allogeneic haematopoietic stem cell transplantation: report from the Consensus Conference on Clinical Practice in chronic graft-versus-host disease.
O. Grauer, D. Wolff, H. Bertz, H. Greinix +6 more
2010Brain : a journal of neurology213 citations
Semantic Scholar
CD4+ T effector memory cell dysfunction is associated with the accumulation of granulocytic myeloid-derived suppressor cells in glioblastoma patients.
D. Dubinski, J. Wölfer, M. Hasselblatt, T. Schneider-Hohendorf +4 more
2016Neuro-Oncology166 citations Open access
Semantic Scholar
Combined intracavitary thermotherapy with iron oxide nanoparticles and radiotherapy as local treatment modality in recurrent glioblastoma patients
O. Grauer, M. Jaber, K. Hess, M. Weckesser +4 more
2018Journal of Neuro-Oncology157 citations Open access
Semantic Scholar
TLR Ligands in the Local Treatment of Established Intracerebral Murine Gliomas1
O. Grauer, Johan W. Molling, E. Bennink, Liza W. J. Toonen +3 more
2008Journal of Immunology136 citations
Semantic Scholar
RNOP-09: Pegylated liposomal doxorubicine and prolonged temozolomide in addition to radiotherapy in newly diagnosed glioblastoma - a phase II study
C. Beier, C. Schmid, T. Gorlia, C. Kleinletzenberger +16 more
2009BMC Cancer124 citations Open access
Semantic Scholar
New Aspects of an Old Drug – Diclofenac Targets MYC and Glucose Metabolism in Tumor Cells
E. Gottfried, Sven A. Lang, K. Renner, A. Bosserhoff +13 more
2013PLoS ONE116 citations Open access
Semantic Scholar
Diclofenac inhibits lactate formation and efficiently counteracts local immune suppression in a murine glioma model
Sridhar Reddy Chirasani, P. Leukel, E. Gottfried, Jochen Hochrein +8 more
2013International Journal of Cancer109 citations
Semantic Scholar
Elimination of regulatory T cells is essential for an effective vaccination with tumor lysate‐pulsed dendritic cells in a murine glioma model
O. Grauer, Roger P. M. Sutmuller, W. V. van Maren, J. F. M. Jacobs +4 more
2007International Journal of Cancer96 citations Open access
Semantic Scholar
Tumor Vessel Normalization, Immunostimulatory Reprogramming, and Improved Survival in Glioblastoma with Combined Inhibition of PD-1, Angiopoietin-2, and VEGF
Mariangela Di Tacchio, J. Macas, J. Weissenberger, Kathleen Sommer +22 more
2019Cancer immunology research88 citations
Semantic Scholar
Combination of ALA-induced fluorescence-guided resection and intraoperative open photodynamic therapy for recurrent glioblastoma: case series on a promising dual strategy for local tumor control.
S. Schipmann, M. Müther, L. Stögbauer, S. Zimmer +6 more
2020Journal of Neurosurgery87 citations Open access
Semantic Scholar
Brain invasion and the risk of seizures in patients with meningioma.
K. Hess, D. Spille, Alborz Adeli, P. Sporns +6 more
2019Journal of Neurosurgery77 citations Open access
Semantic Scholar
Ibuprofen and Diclofenac Restrict Migration and Proliferation of Human Glioma Cells by Distinct Molecular Mechanisms
Verena Leidgens, C. Seliger, Birgit Jachnik, T. Welz +6 more
2015PLoS ONE76 citations Open access
Semantic Scholar
Human CCR5high effector memory cells perform CNS parenchymal immune surveillance via GZMK-mediated transendothelial diapedesis.
S. Herich, T. Schneider-Hohendorf, A. Rohlmann, Maryam Khaleghi Ghadiri +17 more
2019Brain : a journal of neurology69 citations Open access
Semantic Scholar
Is Visible Aminolevulinic Acid-Induced Fluorescence an Independent Biomarker for Prognosis in Histologically Confirmed (World Health Organization 2016) Low-Grade Gliomas?
M. Jaber, C. Ewelt, J. Wölfer, B. Brokinkel +4 more
2018Neurosurgery63 citations Open access
Semantic Scholar
Diffuse Astrocytoma, IDH-Wildtype: A Dissolving Diagnosis
M. Hasselblatt, M. Jaber, D. Reuss, O. Grauer +8 more
2018Journal of Neuropathology and Experimental Neurology60 citations
Semantic Scholar
In vivo colocalization of antigen and CpG [corrected] within dendritic cells is associated with the efficacy of cancer immunotherapy.
S. Nierkens, M. D. den Brok, Roger P. M. Sutmuller, O. Grauer +5 more
2008Cancer Research60 citations
Semantic Scholar
The Colony Stimulating Factor-1 Receptor (CSF-1R)-Mediated Regulation of Microglia/Macrophages as a Target for Neurological Disorders (Glioma, Stroke)
Cristina Barca, C. Foray, S. Hermann, U. Herrlinger +6 more
2021Frontiers in Immunology57 citations Open access
Semantic Scholar
Intratumor heterogeneity and T cell exhaustion in primary CNS lymphoma
Michael O. Heming, Svea Haessner, Jolien Wolbert, I-Na Lu +15 more
2022Genome Medicine52 citations Open access
Semantic Scholar
Progressive Multifocal Leukoencephalopathy Treated by Immune Checkpoint Inhibitors
X. Boumaza, Baptiste Bonneau, D. Roos-weil, C. Pinnetti +17 more
2022Annals of Neurology49 citations Open access
Semantic Scholar
TSPO imaging-guided characterization of the immunosuppressive myeloid tumor microenvironment in patients with malignant glioma.
B. Zinnhardt, M. Müther, Wolfgang Roll, Philipp Backhaus +15 more
2020Neuro-Oncology48 citations Open access
Semantic Scholar
Neurocognitive decline in HIV patients is associated with ongoing T-cell activation in the cerebrospinal fluid
O. Grauer, D. Reichelt, U. Grüneberg, H. Lohmann +6 more
2015Annals of Clinical and Translational Neurology45 citations Open access
Semantic Scholar
CD4(+) T cells predominate in cerebrospinal fluid and leptomeningeal and parenchymal infiltrates in cerebral amyloid β-related angiitis.
N. Melzer, A. Harder, C. Gross, J. Wölfer +6 more
2012Archives of Neurology45 citations
Semantic Scholar
Ineffective treatment of PML with pembrolizumab
M. Pawlitzki, T. Schneider-Hohendorf, L. Rolfes, S. Meuth +3 more
2019Neurology: Neuroimmunology & Neuroinflammation43 citations Open access
Semantic Scholar
The genetic landscape of choroid plexus tumors in children and adults.
C. Thomas, Patrick Soschinski, Melissa Zwaig, Spyridon Oikonomopoulos +26 more
2020Neuro-Oncology39 citations Open access
Semantic Scholar
Phase I/II trial of meclofenamate in progressive MGMT-methylated glioblastoma under temozolomide second-line therapy—the MecMeth/NOA-24 trial
T. Zeyen, A. Potthoff, R. Németh, D. Heiland +28 more
2022Trials32 citations Open access
Semantic Scholar
Imaging temozolomide-induced changes in the myeloid glioma microenvironment
C. Foray, S. Valtorta, Cristina Barca, A. Winkeler +10 more
2021Theranostics32 citations Open access
Semantic Scholar
Health-related quality of life and neurocognitive functioning with lomustine-temozolomide versus temozolomide in patients with newly diagnosed, MGMT-methylated glioblastoma (CeTeG/NOA-09): a randomised, multicentre, open-label, phase 3 trial.
J. Weller, T. Tzaridis, F. Mack, J. Steinbach +21 more
2019The Lancet Oncology32 citations Open access
Semantic Scholar
A randomized controlled phase II trial of vaccination with lysate-loaded, mature dendritic cells integrated into standard radiochemotherapy of newly diagnosed glioblastoma (GlioVax): study protocol for a randomized controlled trial
M. Rapp, O. Grauer, M. Kamp, Natalie Sevens +3 more
2018Trials32 citations Open access
Semantic Scholar
Benefits of contrast-enhanced SWI in patients with glioblastoma multiforme
D. Fahrendorf, W. Schwindt, J. Wölfer, A. Jeibmann +6 more
2013European Radiology30 citations
Semantic Scholar
Progressive Multifocal Leukoencephalopathy after Ibrutinib Therapy for Chronic Lymphocytic Leukemia
Mathias Lutz, A. Schulze, E. Rebber, S. Wiebe +6 more
2016Cancer research and treatment : official journal of Korean Cancer Association29 citations Open access
Semantic Scholar
Toll-like receptor triggered dendritic cell maturation and IL-12 secretion are necessary to overcome T-cell inhibition by glioma-associated TGF-β2
O. Grauer, P. Pöschl, A. Lohmeier, G. Adema +1 more
2007Journal of Neuro-Oncology27 citations
Semantic Scholar
The evolution of cranial meningioma surgery—a single-center 25-year experience
Johanna Sicking, Kira Marie Voß, D. Spille, S. Schipmann +8 more
2018Acta Neurochirurgica26 citations
Semantic Scholar
Neurocognitive functioning and health-related quality of life in adult medulloblastoma patients: long-term outcomes of the NOA-07 study
L. Dirven, R. Luerding, D. Beier, E. Bumes +21 more
2020Journal of Neuro-Oncology23 citations Open access
Semantic Scholar
Multimodal Molecular Imaging of the Tumour Microenvironment.
C. Foray, Cristina Barca, Philipp Backhaus, S. Schelhaas +6 more
2020Advances in Experimental Medicine and Biology22 citations
Semantic Scholar
ACTR-58. PHASE III TRIAL OF CCNU/TEMOZOLOMIDE (TMZ) COMBINATION THERAPY VS. STANDARD TMZ THERAPY FOR NEWLY DIAGNOSED MGMT-METHYLATED GLIOBLASTOMA PATIENTS: THE CeTeg/NOA-09 trial
U. Herrlinger, T. Tzaridis, F. Mack, J. Steinbach +30 more
201722 citations Open access
Semantic Scholar
Recurrent cardiac arrest caused by lateral medulla oblongata infarction
Philipp von Heinemann, O. Grauer, G. Schuierer, M. Ritzka +3 more
2009BMJ Case Reports22 citations Open access
Semantic Scholar
Initial experience with [18F]DPA-714 TSPO-PET to image inflammation in primary angiitis of the central nervous system
Philipp Backhaus, Wolfgang Roll, Carolin Beuker, B. Zinnhardt +17 more
2020European Journal of Nuclear Medicine and Molecular Imaging21 citations Open access
Semantic Scholar
Quality of life in the GLARIUS trial randomizing bevacizumab/irinotecan versus temozolomide in newly diagnosed, MGMT-nonmethylated glioblastoma
N. Schäfer, M. Proescholdt, J. Steinbach, A. Weyerbrock +27 more
2018Neuro-Oncology20 citations Open access
Semantic Scholar
Diagnostic impact of additional O-(2-[18F]fluoroethyl)-L-tyrosine (18F-FET) PET following immunotherapy with dendritic cell vaccination in glioblastoma patients
Ann Kristin Schmitz, R. Sorg, G. Stoffels, O. Grauer +6 more
2019British Journal of Neurosurgery19 citations
Semantic Scholar
Glioma Tissue Obtained by Modern Ultrasonic Aspiration with a Simple Sterile Suction Trap for Primary Cell Culture and Pathological Evaluation
J. Schroeteler, R. Reeker, Eric Suero Molina, B. Brokinkel +5 more
2014European Surgical Research18 citations
Semantic Scholar
Regulatory T cells and the PD-L 1 / PD-1 pathway mediate immune suppression in malignant human brain tumors
J. Jacobs, A. Idema, K. Bol, S. Nierkens +7 more
200918 citations
Semantic Scholar
Interrogating Glioma-Associated Microglia and Macrophage Dynamics Under CSF-1R Therapy with Multitracer In Vivo PET/MRI
C. Foray, Cristina Barca, A. Winkeler, S. Wagner +5 more
2022Journal of Nuclear Medicine16 citations Open access
Semantic Scholar
The role of ion channels in malignant brain tumors
O. Simon, Thomas Müntefering, O. Grauer, S. Meuth
2015Journal of Neuro-Oncology16 citations
Semantic Scholar
First multicentric real-life experience with the combination of CCNU and temozolomide in newly diagnosed MGMT promoter methylated IDH wildtype glioblastoma
L. Lazaridis, E. Bumes, Dorothee Cäcilia Spille, T. Schulz +23 more
2022Neuro-Oncology Advances15 citations Open access
Semantic Scholar
Re-irradiation for recurrent glioblastoma multiforme: a critical comparison of different concepts
A. Baehr, D. Trog, M. Oertel, S. Welsch +4 more
2020Strahlentherapie und Onkologie (Print)15 citations
Semantic Scholar
Brain invasion in meningiomas: does surgical sampling impact specimen characteristics and histology?
M. Timme, C. Thomas, D. Spille, W. Stummer +12 more
2019Neurosurgical review15 citations
Semantic Scholar

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