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A. Schirbel · SciRah

Researcher profile · Semantic Scholar

A. Schirbel

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A. Schirbel — researcher profile on SciRah

h-index: 14
Works: 52
Citations: 1,021

Most-cited papers

Impact of pain on health-related quality of life in patients with inflammatory bowel disease.
A. Schirbel, A. Reichert, S. Roll, D. Baumgart +5 more
2010World Journal of Gastroenterology151 citations Open access
Semantic Scholar
Inflammatory bowel disease: Established and evolving considerations on its etiopathogenesis and therapy
A. Schirbel, C. Fiocchi
2010Journal of Digestive Diseases141 citations
Semantic Scholar
T-helper 2 Cytokines, Transforming Growth Factor β1, and Eosinophil Products Induce Fibrogenesis and Alter Muscle Motility in Patients with Eosinophilic Esophagitis
F. Rieder, I. Nonevski, Jie Ma, Zhufeng Ouyang +14 more
2014Gastroenterology135 citations Open access
Semantic Scholar
Pro-angiogenic activity of TLRs and NLRs: a novel link between gut microbiota and intestinal angiogenesis
A. Schirbel, S. Kessler, F. Rieder, G. West +4 more
2012Gastroenterology125 citations Open access
Semantic Scholar
IL-13Rα2-Bearing, Type II NKT Cells Reactive to Sulfatide Self-Antigen Populate the Mucosa of Ulcerative Colitis
I. Fuss, B. Joshi, Zhiqiong Yang, Heba A Degheidy +15 more
2014Gut72 citations Open access
Semantic Scholar
Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing.
Florian Rieder, T. Karrasch, S. Ben-Horin, A. Schirbel +9 more
2012Journal of Crohn's & Colitis62 citations Open access
Semantic Scholar
Selective deletion of MyD88 signaling in α-SMA positive cells ameliorates experimental intestinal fibrosis via post-transcriptional regulation
Shuai Zhao, D. Dejanovic, P. Yao, Shardul Bhilocha +15 more
2020Mucosal Immunology54 citations Open access
Semantic Scholar
The probiotic Escherichia coli strain Nissle 1917 induces gammadelta T cell apoptosis via caspase- and FasL-dependent pathways.
C. Guzy, D. Paclik, A. Schirbel, U. Sonnenborn +2 more
2008International Immunology51 citations Open access
Semantic Scholar
Enteral and parenteral nutrition distinctively modulate intestinal permeability and T cell function in vitro
C. Guzy, A. Schirbel, D. Paclik, B. Wiedenmann +2 more
2009European Journal of Nutrition38 citations
Semantic Scholar
Prostaglandin E2 inhibits migration of colonic lamina propria fibroblasts
F. Rieder, M. Georgieva, A. Schirbel, Monika Artinger +5 more
2010Inflammatory Bowel Diseases37 citations Open access
Semantic Scholar
Characterization of Changes in Serum Anti-Glycan Antibodies in Crohn's Disease – a Longitudinal Analysis
Florian Rieder, R. Lopez, A. Franke, A. Wolf +8 more
2011PLoS ONE33 citations Open access
Semantic Scholar
Characterization of PTPN2 and its use as a biomarker.
Stephanie Bussieres-Marmen, A. Hutchins, A. Schirbel, N. Rebert +4 more
2014Methods23 citations
Semantic Scholar
Mutual Regulation of TLR/NLR and CEACAM1 in the Intestinal Microvasculature: Implications for IBD Pathogenesis and Therapy.
A. Schirbel, N. Rebert, T. Sadler, G. West +6 more
2018Inflammatory Bowel Diseases20 citations Open access
Semantic Scholar
TNFα inhibitors restrict T cell activation and cycling via Notch-1 signalling in inflammatory bowel disease
L. Werner, U. Berndt, D. Paclik, S. Danese +2 more
2011Gut20 citations
Semantic Scholar
Targeting the innate immune system in pediatric inflammatory bowel disease
A. Schirbel, C. Fiocchi
2011Expert Review of Gastroenterology & Hepatology12 citations
Semantic Scholar
Activation of Toll-Like Receptor (TLR) 5 Induces a PRO-Fibrogenic Phenotype on Human Intestinal Myofibroblasts (HIF) – A Novel Pathway Mediated by Caspase 1
F. Rieder, Shardul Bhilocha, A. Schirbel, Zhufeng Ouyang +5 more
201111 citations
Semantic Scholar
Intestinal epithelial cells and T cells differentially recognize and respond to Candida albicans yeast and hypha
A. Schirbel, D. Shouval, Betty Hebecker, B. Hube +2 more
2018European Journal of Immunology7 citations Open access
Semantic Scholar
192 Pro-Fibrogenic Activity of Toll-Like Receptor (TLR) and NOD-Like Receptor (NLR) Ligands on Human Intestinal Myofibroblasts (HIF) – Linking Bacterial Innate Immunity to Intestinal Fibrosis
F. Rieder, A. Schirbel, Zhufeng Ouyang, G. West +3 more
20107 citations Open access
Semantic Scholar
Single-cell microbiota phenotyping reveals distinct disease and therapy-associated signatures in Crohn’s disease
L. Budzinski, Gi-Ung Kang, René Riedel, Toni Sempert +27 more
2025Gut microbes6 citations Open access
Semantic Scholar
598 Eosinophil Derived TGF-ß1 Activates Human Esophageal Mesenchymal Cells and Alters Esophageal Motility - Implications for Dysphagia in Eosinophilic Esophagitis (EoE)
F. Rieder, I. Nonevski, Jie Ma, Zhufeng Ouyang +11 more
20126 citations Open access
Semantic Scholar
Mo1334 Reasons for the Delay of Diagnosis in Inflammatory Bowel Disease
A. Degen, C. Büning, B. Siegmund, M. Prager +5 more
20132 citations
Semantic Scholar
Imaging in inflammatory bowel disease mucosal healing in ulcerative colitis: relevance for clinical outcomes.
A. Schirbel, A. Sturm
2012Current Drug Targets2 citations
Semantic Scholar
Patient-reported continuous clinical response to golimumab in adults with moderately to severely active ulcerative colitis: results from GO OBSERVE, a real-world European observational study
M. Ferrante, A. Schirbel, M. Pierik, T. Haas +6 more
2022European Journal of Gastroenterology and Hepathology1 citations
Semantic Scholar
Selective deletion of MyD88 signaling in α-SMA positive cells ameliorates experimental intestinal fibrosis via post-transcriptional regulation
Shuai Zhao, D. Dejanovic, P. Yao, Shardul Bhilocha +15 more
2020Mucosal Immunology1 citations Open access
Semantic Scholar
626 - Selective Deletion of MYD88 Signaling in α-SMA Positive Cells Ameliorates Experimental Intestinal Fibrosis via Posttranscriptional Regulation
D. Dejanovic, Shuai Zhao, M. Cruise, Shardul Bhilocha +8 more
20181 citations
Semantic Scholar
O-030 YI Toll-like Receptor (TLR) 5 Promotes a Pro-fibrogenic Phenotype in Human Intestinal Fibroblasts (HIF) via MyD88, Caspase-1 and Posttranscriptional Regulation
F. Rieder, Shardul Bhilocha, A. Schirbel, P. Yao +7 more
20131 citations
Semantic Scholar
CEACAM1-Mediated Angiogenesis by Activation of Toll-Like (TLR) and NOD-Like (NLR) Receptors of Human Intestinal Mucosal Endothelial Cells in IBD
A. Schirbel, F. Rieder, M. Phillips, G. West +1 more
20111 citations Open access
Semantic Scholar
T1257 Characterization of Changes of Serum Anti-Glycan Antibodies in Individual Patients Over Time in Inflammatory Bowel Disease (IBD)
Florian Rieder, S. Schleder, A. Wolf, A. Schirbel +7 more
20101 citations Open access
Semantic Scholar
T1691 Lack of Tolerization and Cross-Tolerization of Intestinal Mesenchymal and Endothelial Cells to Bacterial Products and TNF-α: A Novel Mechanism to Sustain and Amplify Gut Inflammation
Franco Scaldaferri, M. Phillips, M. Rhee, F. Rieder +4 more
20091 citations
Semantic Scholar
Diagnostic delay in inflammatory bowel diseases in a German population
E. Blüthner, Annalena Dehe, C. Büning, B. Siegmund +10 more
2024World Journal of Gastroenterology0 citations Open access
Semantic Scholar
P239 Real-life clinical and quality of life outcomes collected remotely from patients with moderate to severe active ulcerative colitis during induction treatment with golimumab in GO OBSERVE
F. Cornillie, M. Flamant, T. Haas, E. Jorgensen +4 more
2019Journal of Crohn's & Colitis0 citations
Semantic Scholar
SUN-PO198: The Prevalence of Malnutrition According to the New GLIM Definition in Chronic Small and Large Intestinal Diseases
B. Knappe-Drzikova, S. Maasberg, D. Vonderbeck, S. Knuppel +5 more
2019Clinical Nutrition0 citations
Semantic Scholar
P116 Escherichia coli Nissle 1917 distinctively regulates apoptosis and cell cycling of Caco-2 cells.
A. Schirbel, A. Sturm
2017Journal of Crohn's & Colitis0 citations Open access
Semantic Scholar
P115 The influence of maternal IBD on childbirth and further development of children
L. Stoehr, B. Bokemeyer, C. Buening, A. Dignass +10 more
20140 citations Open access
Semantic Scholar
P158Real-time strain elastography accurately differentiates between inﬂammatory and ﬁbrotic strictures in Crohn’s disease
A. Degen, C. Büning, B. Siegmund, M. Prager +19 more
20130 citations
Semantic Scholar
P157 Reasons for a delayed diagnosis in inflammatory bowel disease
A. Degen, C. Büning, B. Siegmund, M. Prager +5 more
20130 citations Open access
Semantic Scholar
P156 Reduction in colectomy- and health care-related costs in ulcerative colitis patients treated with adalimumab compared with standard therapy
A. Degen, C. Büning, B. Siegmund, M. Prager +15 more
20130 citations
Semantic Scholar
Expression of T Cell Protein Tyrosine Phosphatase (PTPN2) is Enhanced in Mucosal T Cells in IBD Patients
A. Schirbel, Stephanie Bussieres-Marmen, J. Achkar, F. Rieder +4 more
20110 citations
Semantic Scholar
871 Eosinophilic Esophagitis (EoE)-Associated Eosinophil Products and Cytokines Reduce Neurogenic Esophageal Smooth Muscle Contractility
F. Rieder, I. Nonevski, Jie Ma, Zhufeng Ouyang +7 more
20100 citations Open access
Semantic Scholar
504 Induction of Angiogenesis by Distinct Toll-Like (TLR) and NOD-Like (NLR) Receptors: Evidence for Bacteria-Mediated Angiogenesis in IBD
A. Schirbel, F. Rieder, Franco Scaldaferri, M. Phillips +3 more
20100 citations Open access
Semantic Scholar
638 Toll-Like (TLR) and NOD-Like (NLR) Receptor Activation of Mucosal Endothelial Cells Upregulates Ceacam1 Expression and Induces Ceacam1-Mediated Angiogenesis
A. Schirbel, F. Rieder, Franco Scaldaferri, M. Phillips +2 more
20100 citations
Semantic Scholar
912 Increased Expression of T Cell Protein Tyrosine Phosphatase (Tc-Ptp) PTPN2 by Mucosal T Cells in IBD Patients
A. Schirbel, J. Achkar, F. Rieder, M. Phillips +2 more
20100 citations
Semantic Scholar
S23 Induction of angiogenesis by distinct Nod-like (NLR) and Toll-like (TLR) receptors: Linking innate immunity to bacteria and angiogenesis in IBD
A. Schirbel, F. Rieder, Franco Scaldaferri, M. Phillips +2 more
20100 citations Open access
Semantic Scholar
W1700 Eosinophils and Their Products Activate Human Esophageal Mesenchymal Cells – Implications for Fibrogenesis in Eosinophilic Esophagitis (EoE)
F. Rieder, I. Nonevski, Zhufeng Ouyang, G. West +6 more
20100 citations
Semantic Scholar
MODULATION OF T CELL REGULATORY FUNCTION BY INTESTINAL FIBROBLASTS: WHERE INFLAMMATION INHIBITS IMMUNE-REGULATION
F. Scaldaferri, F. Rieder, A. Schirbel, G. West +4 more
20090 citations
Semantic Scholar
Results of analyses with lactoferrin-repleted granulocytes
L. Komorowski, B. Teegen, K. Aulinger-Stöcker, S. Niemann +11 more
20090 citations
Semantic Scholar
LACK OF TOLERIZATION OF INTESTINAL MESENCHYMAL AND ENDOTHELIAL CELLS TO BACTERIAL PRODUCTS AND TNF-α: A NOVEL MECHANISM FOR INTESTINAL CHRONIC INFLAMMATION
Franco Scaldaferri, M. Phillips, F. Rieder, A. Schirbel +4 more
20090 citations
Semantic Scholar
T1681 Inflammation-Induced Mucosal Endothelial-to-Mesenchymal Transition (EndoMT): A Novel Mechanism Contributing to the Development of Intestinal Fibrosis
F. Rieder, S. Kessler, Franco Scaldaferri, A. Schirbel +3 more
20090 citations
Semantic Scholar
P285 - Mucosal nonimmune cells produce pro-inflammatory mediators in response to Toll-like (TLRs) and Nod-like receptor (NLRs) ligands: mesenchymal and endothelial cells as novel players of intestinal innate immunity
Franco Scaldaferri, M. Phillips, F. Rieder, A. Schirbel +3 more
20090 citations
Semantic Scholar
P265 - Induction and modulation of T cell regulatory function by intestinal fibroblasts: inhibitory effect of intestinal inflammation
Franco Scaldaferri, M. Rhee, F. Rieder, A. Schirbel +4 more
20090 citations
Semantic Scholar

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C. Fiocchi×29
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C. Fiocchi — researcher profile on SciRah
G. West×26
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F. Rieder×25
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F. Rieder — researcher profile on SciRah
A. Sturm×11
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A. Sturm — researcher profile on SciRah

Franco Scaldaferri

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