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Nathan Brinkman · SciRah

Researcher profile · Semantic Scholar

Nathan Brinkman

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Nathan Brinkman — researcher profile on SciRah

h-index: 8
Works: 16
Citations: 665

Most-cited papers

Hemopexin therapy reverts heme-induced proinflammatory phenotypic switching of macrophages in a mouse model of sickle cell disease.
F. Vinchi, M. Costa da Silva, G. Ingoglia, S. Petrillo +5 more
2016Blood249 citations Open access
Semantic Scholar
Intravascular hemolysis activates complement via cell-free heme and heme-loaded microvesicles.
N. Merle, Anne Grunenwald, Helena Rajaratnam, V. Gnemmi +22 more
2018JCI Insight164 citations Open access
Semantic Scholar
Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction
J. Belcher, Chun-Sheng Chen, J. Nguyen, F. Abdulla +9 more
2018PLoS ONE103 citations Open access
Semantic Scholar
Characterization of Renal Injury and Inflammation in an Experimental Model of Intravascular Hemolysis
N. Merle, Anne Grunenwald, M. Figueres, S. Chauvet +17 more
2018Frontiers in Immunology53 citations Open access
Semantic Scholar
Plasma-Derived Hemopexin as a Candidate Therapeutic Agent for Acute Vaso-Occlusion in Sickle Cell Disease: Preclinical Evidence
T. Gentinetta, J. Belcher, Valérie Brügger-Verdon, J. Adam +25 more
2022Journal of Clinical Medicine35 citations Open access
Semantic Scholar
Cell-free oxidized hemoglobin drives reactive oxygen species production and pro-inflammation in an immature primary rat mixed glial cell culture
A. Agyemang, Suvi Vallius Kvist, Nathan Brinkman, T. Gentinetta +5 more
2021Journal of Neuroinflammation21 citations Open access
Semantic Scholar
Haptoglobin treatment contributes to regulating nitric oxide signal and reduces oxidative stress in the penis: A preventive treatment for priapism in sickle cell disease
P. da Silva Pereira, D. A. Pereira, F. Calmasini, L. Reis +4 more
2022Frontiers in Physiology16 citations Open access
Semantic Scholar
TARGETING LUNG HEME IRON BY AEROSOL HEMOPEXIN ADMINSTRATION IN SICKLE CELL DISEASE PULMONARY HYPERTENSION
Melissa J. Lucero, C. Lisk, F. Cendali, D. Swindle +20 more
2025Free Radical Biology & Medicine8 citations Open access
Semantic Scholar
COMBINED HAPTOGLOBIN AND HEMOPEXIN THERAPY FOR THE TREATMENT OF CARDIOPULMONARY DYSFUNCTION IN SICKLE CELL DISEASE
Melissa J. Lucero, C. Lisk, D. Swindle, F. Cendali +23 more
2025Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie7 citations Open access
Semantic Scholar
Purified and Recombinant Hemopexin: Protease Activity and Effect on Neutrophil Chemotaxis
Tian Lin, Jialin Liu, Feng Huang, T. S. R. van Engelen +8 more
2016Molecular Medicine6 citations Open access
Semantic Scholar
Haptoglobin and Hemopexin Infusion Efficiently Activates the Nrf2/HO-1 Axis and Inhibits Inflammation and Vaso-Occlusion in Murine Sickle Cell Disease
J. Belcher, Chun-Sheng Chen, J. Nguyen, F. Abdulla +5 more
20163 citations
Semantic Scholar
Prevention of Heme-Induced Human Endothelial Cell Activation By Hemopexin in Vitro
J. Adam, T. Gentinetta, Svetlana Diditchenko, Alexander Schaub +3 more
20201 citations
Semantic Scholar
Intravascular hemolysis induces complement system activation
N. Merle, Anne Grunenwald, Helena Rajaratnam, V. Gnemmi +14 more
20171 citations
Semantic Scholar
Cell-free oxidized hemoglobin drives reactive oxygen species production and pro-inflammation in an immature primary rat mixed glial cell culture
A. Agyemang, Suvi Vallius Kvist, Nathan Brinkman, T. Gentinetta +5 more
2021Journal of Neuroinflammation0 citations Open access
Semantic Scholar
Microvascular Stasis Inhibition By Hemopexin in the Townes Mouse Model of Sickle Cell Disease
T. Gentinetta, G. Vercellotti, Chun-Sheng Chen, J. Nguyen +6 more
20200 citations Open access
Semantic Scholar
The Heme Scavenger Hemopexin Reverts Heme-Driven Pro-Inflammatory Phenotypic Switching of Macrophages in Sickle Cell Disease
F. Vinchi, M. C. da Silva, G. Ingoglia, S. Petrillo +5 more
20150 citations
Semantic Scholar

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