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Valerie W. Hu · SciRah

Researcher profile · Semantic Scholar

Valerie W. Hu

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Valerie W. Hu — researcher profile on SciRah

h-index: 30
Works: 82
Citations: 4,560

Most-cited papers

The Cell Cycle
Valerie W. Hu
1994GWUMC Department of Biochemistry Annual Spring Symposia1,244 citations
Semantic Scholar
Global methylation profiling of lymphoblastoid cell lines reveals epigenetic contributions to autism spectrum disorders and a novel autism candidate gene, RORA, whose protein product is reduced in autistic brain
Anhthu N Nguyen, T. Rauch, G. Pfeifer, Valerie W. Hu
2010The FASEB Journal363 citations Open access
Semantic Scholar
Sex Hormones in Autism: Androgens and Estrogens Differentially and Reciprocally Regulate RORA, a Novel Candidate Gene for Autism
Tewarit Sarachana, Min-Yi Xu, Ray-Chang Wu, Valerie W. Hu
2011PLoS ONE222 citations Open access
Semantic Scholar
Gene expression profiling of lymphoblastoid cell lines from monozygotic twins discordant in severity of autism reveals differential regulation of neurologically relevant genes
Valerie W. Hu, Bryan Frank, S. Heine, N. Lee +1 more
2006BMC Genomics222 citations Open access
Semantic Scholar
Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines
Tewarit Sarachana, R. Zhou, Guang Chen, H. Manji +1 more
2010Genome Medicine217 citations Open access
Semantic Scholar
Gene Expression Profiling Differentiates Autism Case–Controls and Phenotypic Variants of Autism Spectrum Disorders: Evidence for Circadian Rhythm Dysfunction in Severe Autism
Valerie W. Hu, Tewarit Sarachana, K. Kim, Anhthu N Nguyen +5 more
2009Autism Research210 citations Open access
Semantic Scholar
Gene Expression Profiling of Lymphoblasts from Autistic and Nonaffected Sib Pairs: Altered Pathways in Neuronal Development and Steroid Biosynthesis
Valerie W. Hu, Anhthu N Nguyen, K. Kim, Mara E. Steinberg +5 more
2009PLoS ONE160 citations Open access
Semantic Scholar
Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder
Tewarit Sarachana, Valerie W. Hu
2013Molecular Autism124 citations Open access
Semantic Scholar
Novel clustering of items from the Autism Diagnostic Interview-Revised to define phenotypes within autism spectrum disorders
Valerie W. Hu, Mara E. Steinberg
2009Autism Research123 citations Open access
Semantic Scholar
Epigenetic Research in Neuropsychiatric Disorders: the “Tissue Issue”
K. Bakulski, A. Halladay, Valerie W. Hu, J. Mill +1 more
2016Current Behavioral Neuroscience Reports118 citations Open access
Semantic Scholar
A Mitosis-specific Phosphorylation of the Gap Junction Protein Connexin43 in Human Vascular Cells: Biochemical Characterization and Localization
Han-Qing Xie, D. Laird, Tsg-Hui Chang, Valerie W. Hu
1997Journal of Cell Biology95 citations Open access
Semantic Scholar
Investigation of sex differences in the expression of RORA and its transcriptional targets in the brain as a potential contributor to the sex bias in autism
Valerie W. Hu, Tewarit Sarachana, R. Sherrard, Kristen Kocher
2015Molecular Autism80 citations Open access
Semantic Scholar
Are endocrine disrupting compounds environmental risk factors for autism spectrum disorder?
Amer Moosa, Henry T. Shu, Tewarit Sarachana, Valerie W. Hu
2017Hormones and Behavior73 citations Open access
Semantic Scholar
Novel Autism Subtype-Dependent Genetic Variants Are Revealed by Quantitative Trait and Subphenotype Association Analyses of Published GWAS Data
Valerie W. Hu, A. Addington, Alexander Hyman
2011PLoS ONE71 citations Open access
Semantic Scholar
Differential recruitment of coregulators to the RORA promoter adds another layer of complexity to gene (dys) regulation by sex hormones in autism
Tewarit Sarachana, Valerie W. Hu
2013Molecular Autism66 citations Open access
Semantic Scholar
Modulation of gap junctions in senescent endothelial cells.
Han-Qing Xie, Valerie W. Hu
1994Experimental Cell Research66 citations
Semantic Scholar
3H‐thymidine is a defective tool with which to measure rates of DNA synthesis
Valerie W. Hu, G. Black, A. Torres-Duarte, Fred P. Abramson
2002The FASEB Journal59 citations
Semantic Scholar
Sex Differences in the Effects of Prenatal Bisphenol A Exposure on Genes Associated with Autism Spectrum Disorder in the Hippocampus
Surangrat Thongkorn, S. Kanlayaprasit, D. Jindatip, T. Tencomnao +2 more
2019Scientific Reports58 citations Open access
Semantic Scholar
Chelation of iron within the erythrocytic Plasmodium falciparum parasite by iron chelators.
M. Loyevsky, C. John, B. Dickens, Valerie W. Hu +2 more
1999Molecular and biochemical parasitology (Print)54 citations
Semantic Scholar
Investigation of epigenetic regulatory networks associated with autism spectrum disorder (ASD) by integrated global LINE-1 methylation and gene expression profiling analyses
Chayanin Tangsuwansri, Thanit Saeliw, Surangrat Thongkorn, W. Chonchaiya +5 more
2018PLoS ONE52 citations Open access
Semantic Scholar
From Genes to Environment: Using integrative genomics to build a “systems level” understanding of autism spectrum disorders
Valerie W. Hu
2012Child Development51 citations Open access
Semantic Scholar
Prenatal exposure to bisphenol A alters the transcriptome-interactome profiles of genes associated with Alzheimer’s disease in the offspring hippocampus
Suporn Sukjamnong, Surangrat Thongkorn, S. Kanlayaprasit, Thanit Saeliw +5 more
2020Scientific Reports49 citations Open access
Semantic Scholar
Integrated genome-wide Alu methylation and transcriptome profiling analyses reveal novel epigenetic regulatory networks associated with autism spectrum disorder
Thanit Saeliw, Chayanin Tangsuwansri, Surangrat Thongkorn, W. Chonchaiya +5 more
2018Molecular Autism49 citations Open access
Semantic Scholar
Sex differences in the effects of prenatal bisphenol A exposure on autism-related genes and their relationships with the hippocampus functions
Surangrat Thongkorn, S. Kanlayaprasit, Pawinee Panjabud, Thanit Saeliw +10 more
2021Scientific Reports46 citations Open access
Semantic Scholar
Metabolic radiolabeling: experimental tool or Trojan horse? 35S‐Methionine induces DNA fragmentation and p53‐dependent ROS production
Valerie W. Hu, Daniel S. Heikka, Paul B. Dieffenbach, Unan Ha
2001The FASEB Journal39 citations
Semantic Scholar
Autism-Related Transcription Factors Underlying the Sex-Specific Effects of Prenatal Bisphenol A Exposure on Transcriptome-Interactome Profiles in the Offspring Prefrontal Cortex
S. Kanlayaprasit, Surangrat Thongkorn, Pawinee Panjabud, D. Jindatip +4 more
2021International Journal of Molecular Sciences38 citations Open access
Semantic Scholar
Developing a Predictive Gene Classifier for Autism Spectrum Disorders Based upon Differential Gene Expression Profiles of Phenotypic Subgroups
Valerie W. Hu, Y. Lai
2013North American Journal of Medicine and Science36 citations
Semantic Scholar
Investigation of autism-related transcription factors underlying sex differences in the effects of bisphenol A on transcriptome profiles and synaptogenesis in the offspring hippocampus
Surangrat Thongkorn, S. Kanlayaprasit, Kasidit Kasitipradit, Pattanachat Lertpeerapan +4 more
2023Biology of Sex Differences33 citations Open access
Semantic Scholar
Interleukin-1α suppresses gap junction-mediated intercellular communication in human endothelial cells
Valerie W. Hu, Han-Qing Xie
199433 citations
Semantic Scholar
Does metabolic radiolabeling stimulate the stress response? Gene expression profiling reveals differential cellular responses to internal beta vs. external gamma radiation
Nicholas F. Marko, Paul B. Dieffenbach, Gai Yan, S. Ceryak +3 more
2003The FASEB Journal32 citations
Semantic Scholar
Transcriptomic analysis of glutamate-induced HT22 neurotoxicity as a model for screening anti-Alzheimer’s drugs
A. Prasansuklab, Suporn Sukjamnong, Atsadang Theerasri, Valerie W. Hu +2 more
2023Scientific Reports30 citations Open access
Semantic Scholar
Phenotypic subgrouping and multi-omics analyses reveal reduced diazepam-binding inhibitor (DBI) protein levels in autism spectrum disorder with severe language impairment
Chatravee Pichitpunpong, Surangrat Thongkorn, S. Kanlayaprasit, Wasana Yuwattana +7 more
2019PLoS ONE30 citations Open access
Semantic Scholar
Radiolabeling revisited: metabolic labeling with 35S‐methionine inhibits cell cycle progression, proliferation, and survival
Valerie W. Hu, Daniel S. Heikka
2000The FASEB Journal30 citations
Semantic Scholar
LINE-1 and Alu methylation signatures in autism spectrum disorder and their associations with the expression of autism-related genes
Thanit Saeliw, Tiravut Permpoon, Nutta Iadsee, T. Tencomnao +4 more
2022Scientific Reports29 citations Open access
Semantic Scholar
Is retinoic acid-related orphan receptor-alpha (RORA) a target for gene-environment interactions contributing to autism?
Valerie W. Hu
2012Neurotoxicology27 citations
Semantic Scholar
The expanding genomic landscape of autism: discovering the ‘forest’ beyond the ‘trees’
Valerie W. Hu
2013Future Neurology26 citations Open access
Semantic Scholar
Single mutation in the A domain of diphtheria toxin results in a protein with altered membrane insertion behavior.
Valerie W. Hu, Randall K. Holmes
1987Biochimica et Biophysica Acta25 citations
Semantic Scholar
Epigenetic Gene-Regulatory Loci in Alu Elements Associated with Autism Susceptibility in the Prefrontal Cortex of ASD
Thanit Saeliw, S. Kanlayaprasit, Surangrat Thongkorn, Kwanjira Songsritaya +5 more
2023International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
A Novel Stratification Method in Linkage Studies to Address Inter- and Intra-Family Heterogeneity in Autism
Z. Talebizadeh, D. Arking, Valerie W. Hu
2013PLoS ONE21 citations Open access
Semantic Scholar
The cell cycle : regulators, targets, and clinical applications
Valerie W. Hu
199421 citations
Semantic Scholar
ASD Phenotype—Genotype Associations in Concordant and Discordant Monozygotic and Dizygotic Twins Stratified by Severity of Autistic Traits
Valerie W. Hu, C. Devlin, Jessica Debski
2019International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
Altered DNA methylation in a severe subtype of idiopathic autism: Evidence for sex differences in affected metabolic pathways
Valerie W. Hu, Yi Hong, Min-Yi Xu, Henry T. Shu
2020Autism17 citations
Semantic Scholar
Subphenotype-Dependent Disease Markers for Diagnosis and Personalized Treatment of Autism Spectrum Disorders
Valerie W. Hu
2012Disease Markers17 citations
Semantic Scholar
Sex-specific impacts of prenatal bisphenol A exposure on genes associated with cortical development, social behaviors, and autism in the offspring’s prefrontal cortex
S. Kanlayaprasit, Thanit Saeliw, Surangrat Thongkorn, Pawinee Panjabud +10 more
2024Biology of Sex Differences16 citations Open access
Semantic Scholar
Machine learning of clinical phenotypes facilitates autism screening and identifies novel subgroups with distinct transcriptomic profiles
Wasana Yuwattana, Thanit Saeliw, M. L. van Erp, Chayanit Poolcharoen +5 more
2025Scientific Reports15 citations Open access
Semantic Scholar
Intercellular communication through gap junctions is reduced in senescent cells.
Han-Qing Xie, Ruo Huang, Valerie W. Hu
1992Biophysical Journal13 citations Open access
Semantic Scholar
Fluorescence analysis of size distribution and mode of dye release from carboxyfluorescein-loaded vesicles: application to the study of complement-membrane interactions.
Zi-Yao Liu, R. Solow, Valerie W. Hu
1988Biochimica et Biophysica Acta13 citations
Semantic Scholar
Phenotypic Subtyping and Re-Analysis of Existing Methylation Data from Autistic Probands in Simplex Families Reveal ASD Subtype-Associated Differentially Methylated Genes and Biological Functions
Elizabeth C. Lee, Valerie W. Hu
2020International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
Prenatal exposure to bisphenol A disrupts RNA splicing in the prefrontal cortex and promotes behaviors related to autism in offspring
Pawinee Panjabud, S. Kanlayaprasit, Surangrat Thongkorn, Kwanjira Songsritaya +8 more
2025Scientific Reports11 citations Open access
Semantic Scholar
Sex-specific effects of prenatal bisphenol A exposure on transcriptome-interactome profiles of autism candidate genes in neural stem cells from offspring hippocampus
Kasidit Kasitipradit, Surangrat Thongkorn, S. Kanlayaprasit, Thanit Saeliw +7 more
2025Scientific Reports11 citations Open access
Semantic Scholar

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S. Kanlayaprasit×11
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Han-Qing Xie×4

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