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P. Lao · SciRah

Researcher profile · Semantic Scholar

P. Lao

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P. Lao — researcher profile on SciRah

h-index: 24
Works: 206
Citations: 2,159

Most-cited papers

Tau PET positivity in individuals with and without cognitive impairment varies with age, amyloid-β status, APOE genotype and sex
R. Ossenkoppele, E. Coomans, Liana G. Apostolova, S. Baker +93 more
2025Nature Neuroscience64 citations Open access
Semantic Scholar
Microglia measured by TSPO PET are associated with Alzheimer's disease pathology and mediate key steps in a disease progression model
Samantha M. Rossano, Aubrey S. Johnson, Anna C. Smith, Galen Ziaggi +10 more
2024Alzheimer's & Dementia48 citations Open access
Semantic Scholar
Development, initial validation, and application of a visual read method for [18F]MK‐6240 tau PET
J. Shuping, D. Matthews, Katarzyna Adamczuk, David Scott +24 more
2023Alzheimer's & Dementia33 citations Open access
Semantic Scholar
Cerebrovascular disease emerges with age and Alzheimer’s disease in adults with Down syndrome
P. Lao, Natalie C. Edwards, Lisi Flores-Aguilar, M. Alshikho +12 more
2024Scientific Reports31 citations Open access
Semantic Scholar
Cerebrovascular disease is associated with Alzheimer’s plasma biomarker concentrations in adults with Down syndrome
Natalie C. Edwards, P. Lao, M. Alshikho, Olivia M. Ericsson +21 more
2024Brain Communications21 citations Open access
Semantic Scholar
Loneliness, cerebrovascular and Alzheimer's disease pathology, and cognition
P. Lao, Christina B. Young, C. Ezeh, Bayardo E Lacayo +10 more
2024Alzheimer's & Dementia16 citations Open access
Semantic Scholar
Resistance and resilience to Alzheimer's disease in Down syndrome
R. Boyle, E. Koops, B. Ances, Elizabeth J. Andrews +41 more
2025Alzheimer's & Dementia13 citations Open access
Semantic Scholar
Depressive Symptoms Correlate With Tau Accumulation Rates in Amyloid Positive Adults
D. Talmasov, A. Johnson, P. Brown, F. Provenzano +3 more
2025The American journal of geriatric psychiatry12 citations Open access
Semantic Scholar
Clinical and research application of fluid biomarkers in autosomal dominant Alzheimer's disease and Down syndrome
M. Carmona-Iragui, Antoinette O'Connor, J. Llibre-Guerra, P. Lao +3 more
2024EBioMedicine12 citations Open access
Semantic Scholar
Alzheimer’s disease, vascular disease, and blood-brain barrier permeability biomarkers in middle-aged adults
Natalie C. Edwards, P. Lao, M. Alshikho, Jessica Mazen +12 more
2025Neurology9 citations
Semantic Scholar
Small vessel cerebrovascular disease is associated with cognition in prospective Alzheimer’s clinical trial participants
Clarissa D. Morales, Dejania Cotton-Samuel, P. Lao, Julia F. Chang +10 more
2024Alzheimer's Research & Therapy9 citations Open access
Semantic Scholar
Regional differences in astrocytic Aquaporin-4 protein levels and distribution in aging and Alzheimer’s disease in down syndrome
Cherie A. Stringer, Haley Miyasato, Kevin Camey, Krina A Ghadia +18 more
2025Neurobiology of Disease8 citations Open access
Semantic Scholar
Decoding brain structure to stage Alzheimer's disease pathology in Down syndrome
James T. Kennedy, Julie K. Wisch, A. Dincer, June Roman +13 more
2025Alzheimer's & Dementia8 citations Open access
Semantic Scholar
The striatum is an early, accurate indicator of amyloid burden using [11C]PiB in Down syndrome: comparison of two radiotracers
Max J. McLachlan, Brecca Bettcher, Andrew McVea, Alexandra DiFillipo +20 more
2024medRxiv8 citations Open access
Semantic Scholar
Sex Differences in Alzheimer Disease Imaging Biomarkers in a Diverse, Community-Based Cohort
Muge Akinci, Froogh Aziz, P. Palta, D. Guzman +5 more
2026JAMA Network Open7 citations Open access
Semantic Scholar
The striatum is an early, accurate indicator of amyloid burden using [11C]PiB in Down syndrome: Comparison of two radiotracers
Max J. McLachlan, Brecca Bettcher, Andrew McVea, A. DiFilippo +22 more
2025Alzheimer's & Dementia7 citations Open access
Semantic Scholar
Amyloid PET Quantitation and Centiloid Thresholds in the Diagnosis of Alzheimer Disease: An Individual Participant Data Meta-Analysis.
G. Blazhenets, D. Soleimani-Meigooni, Konstantinos Chiotis, I. E. Allen +116 more
2026Journal of the American Medical Association (JAMA)6 citations Open access
Semantic Scholar
PET‐measured amyloid beta accumulates at an accelerated rate in Down syndrome compared to neurotypical populations
Andrew McVea, A. DiFilippo, Max J. McLachlan, Brecca Betcher +20 more
2025Alzheimer's & Dementia6 citations
Semantic Scholar
Genetically determined Alzheimer's disease research advances: The Down Syndrome & Autosomal Dominant Alzheimer's Disease 2024 Conference
Neus Falgàs, Lucía Maure-Blesa, B. Ances, Lisi Flores-Aguilar +54 more
2025Alzheimer's & Dementia6 citations Open access
Semantic Scholar
Correlating hippocampal and amygdala volumes with neuropathological burden in Down syndrome and Alzheimer’s disease and related neurodegenerative pathologies using 7T postmortem MRI
Jr-Jiun Liou, Jing-Hang Li, J. Berardinelli, He-Cheng Jin +70 more
2025Journal of Neuropathology and Experimental Neurology6 citations Open access
Semantic Scholar
Cerebral blood flow is associated with plasma and PET biomarkers of tau pathology in middle age
A. Houck, M. Alshikho, P. Lao, Jeffrey D. Pyne +11 more
2025Brain Communications5 citations
Semantic Scholar
Longitudinal changes in white matter hyperintensity volume accelerate across the Alzheimer's continuum in adults with Down syndrome
P. Lao, Natalie C. Edwards, Lisi Flores-Aguilar, M. Alshikho +14 more
2025Alzheimer's & Dementia5 citations Open access
Semantic Scholar
Age and sex are associated with Alzheimer's disease neuropathology in Down syndrome
Elizabeth J. Andrews, P. Ngo, Jesse R. Pascual, Freddy Gonzalez +10 more
2025Alzheimer's & Dementia4 citations Open access
Semantic Scholar
Alzheimer's disease diagnostic progression is associated with cerebrovascular disease and neuroinflammation in adults with Down syndrome
Natalie C. Edwards, P. Lao, M. Alshikho, Olivia M. Ericsson +21 more
2025Alzheimer's & Dementia4 citations Open access
Semantic Scholar
Validating noninvasive techniques for 11C‐ER176 PET quantification in controls and Alzheimer’s disease patients
Samantha M. Rossano, D. Talmasov, Aubrey S. Johnson, Anna C. Smith +5 more
2023Alzheimer's & Dementia4 citations Open access
Semantic Scholar
Longitudinal decline in semantic versus letter fluency, but not their ratio, marks incident Alzheimer’s disease in Latinx Spanish-speaking older individuals
K. Fernández, A. Kociolek, P. Lao, Y. Stern +2 more
2023Journal of the International Neuropsychological Society4 citations Open access
Semantic Scholar
Phase contrast-derived cerebral blood flow is associated with neurodegeneration and cerebrovascular injury in older adults
Jeffrey D. Pyne, Clarissa D. Morales, A. Kraal, M. Alshikho +9 more
2025Frontiers in Neuroscience3 citations Open access
Semantic Scholar
The tau biomarker cascade is condensed in Down syndrome compared to sporadic Alzheimer's disease
M. Zammit, Hailey Bruzzone, K. Cody, Jacob Morse +30 more
2025Brain : a journal of neurology3 citations Open access
Semantic Scholar
Psychotic symptoms are associated with elevated tau PET signal in the amygdala independent of Alzheimer’s disease clinical severity and amyloid burden
A. Johnson, G. Ziaggi, A. Smith, H. Houlihan +9 more
2024medRxiv3 citations Open access
Semantic Scholar
Interactions among neighborhood conditions, sleep quality, and episodic memory across the adult lifespan
Emily Hokett, P. Lao, J. Avila-Rieger, Indira C. Turney +9 more
2024Ethnicity and Health3 citations Open access
Semantic Scholar
A pathway linking pulse pressure to dementia in adults with Down syndrome
Batool Rizvi, P. Lao, Mithra T. Sathishkumar, Lisa Taylor +18 more
2024Brain Communications3 citations Open access
Semantic Scholar
White matter aging across the lifespan in Down syndrome: developmental origins, Alzheimer's disease progression, and therapeutic implications
Justine Silva, Jr-Jiun Liou, Simren Parikh, Natalie C. Edwards +10 more
2026npj Dementia2 citations Open access
Semantic Scholar
Neuroimaging Compendium of Microglia, Amyloid, Tau, and Neurodegeneration Across Clinical Variants of Alzheimer Disease
H. Houlihan, D. Guzman, Anna Smith, T. Sanchez +5 more
2025Alzheimer Disease and Associated Disorders2 citations
Semantic Scholar
The relationship between racial discrimination and white matter among Black older adults
Jordan D. Palms, Ji Hyun Lee, E. Morris, Ketlyne Sol +8 more
2025Neurobiology of Aging2 citations
Semantic Scholar
Preliminary investigation of obstructive sleep apnea and Alzheimer’s disease in down syndrome
D. M. Yoon, D. Plante, Victoria L. Fleming, B. Handen +9 more
2025SLEEP Advances2 citations Open access
Semantic Scholar
Cross-Sectional FDG in Down Syndrome and Autosomal Dominant Alzheimer Disease
Omar Abdelmoity, Julie K. Wisch, James T. Kennedy, Manu S. Goyal +27 more
2025Annals of Neurology2 citations Open access
Semantic Scholar
Association of type 2 diabetes treatment status with in vivo biomarkers of Alzheimer's disease
Muge Akinci, Froogh Aziz, D. Guzman, Lina Cheung +7 more
2026Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Associations between sleep and episodic memory performance in a diverse adult lifespan community-based sample: The Offspring study
Emily Hokett, P. Lao, Benjamin D. Huber, Indira C. Turney +5 more
2026Sleep Health1 citations Open access
Semantic Scholar
Preliminary Investigation of Obstructive Sleep Apnea and Alzheimer's Disease in Down Syndrome.
D. M. Yoon, D. Plante, Victoria L. Fleming, B. Handen +9 more
2025Sleep1 citations Open access
Semantic Scholar
Plasma pTau217 as a marker of both the current and future state of amyloid pathology in adults with DS
Julie K. Wisch, Z. Jiao, P. Lao, Natalie C. Edwards +23 more
2025Alzheimer's & Dementia1 citations Open access
Semantic Scholar
The Consortium for Clarity in ADRD Research Through Imaging (CLARiTI): Overview of consortium sites and anticipated enrollment
Julie E. Oomens, Sarah A. Biber, Marilyn S. Albert, M. Alosco +58 more
2025Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Inflammatory Alterations and Multidomain Cognition in Alzheimer Disease and Related Dementias
Anna Smith, D. Guzman, Seonjoo Lee, D. Talmasov +9 more
2025Alzheimer Disease and Associated Disorders1 citations
Semantic Scholar
Brain Volumetric Trajectories in Down Syndrome and Autosomal Dominant Alzheimer Disease
James T. Kennedy, Julie K. Wisch, Brian A. Gordon, Anna H. Boerwinkle +43 more
2024Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Characterizing White Matter Hyperintensity (WMH) Patterns with Texture‐Based Analysis
M. Alshikho, Clarissa D. Morales, Jeffrey D. Pyne, Erica Amarante +7 more
2024Alzheimer's & Dementia1 citations Open access
Semantic Scholar
Alzheimers-associated inflammatory alterations mediate tau-associated neurodegeneration in limbic and temporal regions across clinical variants of Alzheimers disease
P. Lao, S. Lee, D. Talmasov, D. Dass +12 more
2024medRxiv1 citations Open access
Semantic Scholar
Independent and interactive contributions of cerebrovascular disease, neuroinflammation, and tau pathophysiology to Alzheimer’s disease‐related diagnostic conversion in adults with Down syndrome
Natalie C. Edwards, P. Lao, M. Alshikho, Batool Rizvi +9 more
2024Alzheimer's & Dementia1 citations
Semantic Scholar
Hearing Loss Is Associated With Regional Brain Amyloid in a Late Middle-Aged Cohort.
S. Powell, Hannah N. W. Weinstein, Froogh Aziz, A. Brickman +4 more
2026The Laryngoscope0 citations
Semantic Scholar
Multi-dimensional attention framework for personalised Alzheimer's disease progression prediction across sporadic and genetic risk cohorts
Zhi-Yuan Song, Si-Yang Song, Isabel C. H. Clare, Elizabeth Head +21 more
2026Research Square0 citations Open access
Semantic Scholar
Microglia PET Imaging Pre- and Post- Anti-amyloid Treatment with Lecanemab: A Case Study (P1-12.008)
A. Johnson, Anna Smith, D. Guzman, H. Houlihan +5 more
2026Neurology0 citations
Semantic Scholar
Association of total and brain-derived Alzheimer's disease plasma biomarkers with brain amyloid deposition in a community-based sample
Muge Akinci, Froogh Aziz, D. Guzman, Lina Cheung +8 more
2026medRxiv0 citations Open access
Semantic Scholar

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