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N. Gilles · SciRah

Researcher profile · Semantic Scholar

N. Gilles

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N. Gilles — researcher profile on SciRah

h-index: 29
Works: 124
Citations: 2,375

Most-cited papers

The differential preference of scorpion alpha-toxins for insect or mammalian sodium channels: implications for improved insect control.
D. Gordon, Izhar Karbat, N. Ilan, L. Cohen +6 more
2007Toxicon117 citations
Semantic Scholar
Common Features in the Functional Surface of Scorpion β-Toxins and Elements That Confer Specificity for Insect and Mammalian Voltage-gated Sodium Channels*
L. Cohen, Izhar Karbat, N. Gilles, N. Ilan +3 more
2005Journal of Biological Chemistry100 citations Open access
Semantic Scholar
New method for characterizing highly disulfide-bridged peptides in complex mixtures: application to toxin identification from crude venoms.
L. Quinton, Kevin Demeure, Rowan Dobson, N. Gilles +2 more
2007Journal of Proteome Research90 citations
Semantic Scholar
Peptidomic comparison and characterization of the major components of the venom of the giant ant Dinoponera quadriceps collected in four different areas of Brazil.
C. Cologna, Jaqueline dos Santos Cardoso, Emmanuel Jourdan, M. Degueldre +7 more
2013Journal of Proteomics66 citations
Semantic Scholar
Two distinct dopamine D2 receptor genes in the European eel: molecular characterization, tissue-specific transcription, and regulation by sex steroids.
C. Pasqualini, F. Weltzien, B. Vidal, S. Baloche +5 more
2009Endocrinology58 citations
Semantic Scholar
High-throughput expression of animal venom toxins in Escherichia coli to generate a large library of oxidized disulphide-reticulated peptides for drug discovery
J. Turchetto, A. F. Sequeira, Laurie Ramond, Fanny Peysson +11 more
2017Microbial Cell Factories51 citations Open access
Semantic Scholar
Isolation and pharmacological characterization of AdTx1, a natural peptide displaying specific insurmountable antagonism of the α1A‐adrenoceptor
L. Quinton, E. Girard, A. Maiga, M. Rekik +16 more
2010British Journal of Pharmacology51 citations Open access
Semantic Scholar
Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease
J. Ciolek, Helen Reinfrank, L. Quinton, S. Viengchareun +17 more
2017Proceedings of the National Academy of Sciences of the United States of America49 citations Open access
Semantic Scholar
The unique pharmacology of the scorpion α‐like toxin Lqh3 is associated with its flexible C‐tail
Izhar Karbat, Roy Kahn, L. Cohen, N. Ilan +8 more
200746 citations
Semantic Scholar
Identification of a novel snake peptide toxin displaying high affinity and antagonist behaviour for the α2‐adrenoceptors
C. Rouget, L. Quinton, Arhamatoulaye Maïga, C. Galés +8 more
2010British Journal of Pharmacology39 citations Open access
Semantic Scholar
A Spider Toxin That Induces a Typical Effect of Scorpion α-Toxins but Competes with β-Toxins on Binding to Insect Sodium Channels†
G. Corzo, P. Escoubas, E. Villegas, Izhar Karbat +4 more
200539 citations
Semantic Scholar
Gene design, fusion technology and TEV cleavage conditions influence the purification of oxidized disulphide-rich venom peptides in Escherichia coli
A. F. Sequeira, J. Turchetto, N. Saez, Fanny Peysson +11 more
2017Microbial Cell Factories37 citations Open access
Semantic Scholar
Genetic polymorphism and expression of a highly potent scorpion depressant toxin enable refinement of the effects on insect Na channels and illuminate the key role of Asn-58.
D. Strugatsky, N. Zilberberg, M. Stankiewicz, N. Ilan +6 more
2005Biochemistry35 citations
Semantic Scholar
Binding properties to nicotinic acetylcholine receptors can explain differential toxicity of neonicotinoid insecticides in Chironomidae.
E. Maloney, E. Taillebois, N. Gilles, C. A. Morrissey +3 more
2020Aquatic Toxicology31 citations
Semantic Scholar
G protein-coupled receptors, an unexploited animal toxin targets: Exploration of green mamba venom for novel drug candidates active against adrenoceptors.
Arhamatoulaye Maïga, G. Mourier, L. Quinton, C. Rouget +7 more
2012Toxicon31 citations
Semantic Scholar
Direct Evidence That Receptor Site-4 of Sodium Channel Gating Modifiers Is Not Dipped in the Phospholipid Bilayer of Neuronal Membranes*
L. Cohen, N. Gilles, Izhar Karbat, N. Ilan +2 more
2006Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Engineering of Three-Finger Fold Toxins Creates Ligands with Original Pharmacological Profiles for Muscarinic and Adrenergic Receptors
C. Fruchart-Gaillard, G. Mourier, G. Blanchet, L. Vera +5 more
2012PLoS ONE28 citations Open access
Semantic Scholar
Ion mobility mass spectrometry as a potential tool to assign disulfide bonds arrangements in peptides with multiple disulfide bridges.
Julien Echterbille, L. Quinton, N. Gilles, E. De Pauw
2013Analytical Chemistry26 citations
Semantic Scholar
Molecular basis of the high insecticidal potency of scorpion alpha-toxins.
Izhar Karbat, F. Frolow, O. Froy, N. Gilles +4 more
2004Journal of Biological Chemistry26 citations
Semantic Scholar
Fourier transform mass spectrometry: a powerful tool for toxin analysis.
L. Quinton, Jean-Pierre Le Caër, J. Vinh, N. Gilles +1 more
2006Toxicon23 citations
Semantic Scholar
Diversity in sequences, post‐translational modifications and expected pharmacological activities of toxins from four Conus species revealed by the combination of cutting‐edge proteomics, transcriptomics and bioinformatics
M. Degueldre, M. Verdenaud, Garikoitz Legarda, R. Miñambres +6 more
2017Toxicon22 citations
Semantic Scholar
Polypharmacology profiles and phylogenetic analysis of three-finger toxins from mamba venom: case of aminergic toxins.
G. Blanchet, G. Collet, G. Mourier, N. Gilles +3 more
2014Biochimie22 citations
Semantic Scholar
Orthosteric Binding of ρ-Da1a, a Natural Peptide of Snake Venom Interacting Selectively with the α1A-Adrenoceptor
Arhamatoulaye Maïga, Jon Merlin, Elodie Marcon, C. Rouget +12 more
2013PLoS ONE21 citations Open access
Semantic Scholar
TxXIIIA, an atypical homodimeric conotoxin found in the Conus textile venom.
L. Quinton, N. Gilles, E. De Pauw
2009Journal of Proteomics21 citations
Semantic Scholar
Combined use of ion mobility and collision-induced dissociation to investigate the opening of disulfide bridges by electron-transfer dissociation in peptides bearing two disulfide bonds.
P. Massonnet, G. Upert, Nicolas Smargiasso, N. Gilles +2 more
2015Analytical Chemistry20 citations
Semantic Scholar
An Unusual Family of Glycosylated Peptides Isolated from Dendroaspis angusticeps Venom and Characterized by Combination of Collision Induced and Electron Transfer Dissociation
L. Quinton, N. Gilles, Nicolas Smargiasso, A. Kiehne +1 more
2011Journal of the American Society for Mass Spectrometry20 citations
Semantic Scholar
Mammalian Skeletal Muscle Voltage-Gated Sodium Channels Are Affected by Scorpion Depressant “Insect-Selective” Toxins when Preconditioned
L. Cohen, Yael Troub, M. Turkov, N. Gilles +4 more
2007Molecular Pharmacology20 citations
Semantic Scholar
Identification and functional characterization of a novel α-conotoxin (EIIA) from Conus ermineus
L. Quinton, D. Servent, E. Girard, J. Molgó +6 more
2013Analytical and Bioanalytical Chemistry19 citations
Semantic Scholar
Secretion and maturation of conotoxins in the venom ducts of Conus textile.
Rowan Dobson, M. Collodoro, N. Gilles, A. Turtoi +2 more
2012Toxicon19 citations
Semantic Scholar
New α-adrenergic property for synthetic MTβ and CM-3 three-finger fold toxins from black mamba.
G. Blanchet, G. Upert, G. Mourier, B. Gilquin +2 more
2013Toxicon18 citations
Semantic Scholar
A new Kunitz‐type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor
Laura Droctové, J. Ciolek, C. Mendre, Amélia Chorfa +17 more
2021British Journal of Pharmacology17 citations Open access
Semantic Scholar
Ion Mobility-Mass Spectrometry as a Tool for the Structural Characterization of Peptides Bearing Intramolecular Disulfide Bond(s)
P. Massonnet, Jean R. N. Haler, G. Upert, M. Degueldre +6 more
2016Journal of the American Society for Mass Spectrometry17 citations Open access
Semantic Scholar
Pharmacological characterization of zinc and copper interaction with the human alpha(1A)-adrenoceptor.
J. Ciolek, Arhamatoulaye Maïga, Elodie Marcon, D. Servent +1 more
2011European Journal of Pharmacology17 citations
Semantic Scholar
Miniaturization of Scorpion β-Toxins Uncovers a Putative Ancestral Surface of Interaction with Voltage-gated Sodium Channels*♦
L. Cohen, N. Lipstein, Izhar Karbat, N. Ilan +4 more
2008Journal of Biological Chemistry16 citations Open access
Semantic Scholar
A spider toxin that induces a typical effect of scorpion alpha-toxins but competes with beta-toxins on binding to insect sodium channels.
G. Corzo, P. Escoubas, E. Villegas, Izhar Karbat +4 more
2005Biochemistry16 citations
Semantic Scholar
Evaluation of the Spider (Phlogiellus genus) Phlotoxin 1 and Synthetic Variants as Antinociceptive Drug Candidates
T. C. Gonçalves, Pierre Lesport, Sarah Kuylle, E. Stura +6 more
2019Toxins14 citations Open access
Semantic Scholar
The European FP7 Venomics Project.
N. Gilles, D. Servent
2014Future Medicinal Chemistry13 citations
Semantic Scholar
A Venomics approach coupled to high-throughput toxin production strategies identifies the first venom-derived melanocortin receptor agonists.
S. Reynaud, J. Ciolek, M. Degueldre, N. Saez +28 more
2020Journal of Medicinal Chemistry12 citations Open access
Semantic Scholar
Combination of Capillary Zone Electrophoresis-Mass Spectrometry, Ion Mobility-Mass Spectrometry, and Theoretical Calculations for cysteine connectivity identification in peptides bearing two intramolecular disulfide bonds.
Cédric Delvaux, P. Massonnet, Christopher Kune, Jean R. N. Haler +6 more
2019Analytical Chemistry12 citations Open access
Semantic Scholar
Molecular exploration of the α1A‐adrenoceptor orthosteric site: Binding site definition for epinephrine, HEAT and prazosin
Arhamatoulaye Maïga, M. Dupont, G. Blanchet, Elodie Marcon +3 more
2014FEBS Letters12 citations
Semantic Scholar
A snake toxin as a theranostic agent for the type 2 vasopressin receptor
Laura Droctové, M. Lancien, V. Tran, Michaël Susset +17 more
2020Theranostics11 citations Open access
Semantic Scholar
Discovery and characterization of EIIB, a new &agr;‐conotoxin from Conus ermineus venom by nAChRs affinity capture monitored by MALDI‐TOF/TOF mass spectrometry
Julien Echterbille, N. Gilles, R. Aráoz, G. Mourier +4 more
2017Toxicon10 citations
Semantic Scholar
The unique pharmacology of the scorpion alpha-like toxin Lqh3 is associated with its flexible C-tail.
Izhar Karbat, Roy Kahn, L. Cohen, N. Ilan +8 more
2007The FEBS Journal10 citations
Semantic Scholar
In-Depth Glyco-Peptidomics Approach Reveals Unexpected Diversity of Glycosylated Peptides and Atypical Post-Translational Modifications in Dendroaspis angusticeps Snake Venom
M. Degueldre, Julien Echterbille, Nicolas Smargiasso, C. Damblon +5 more
2017International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Disulfide Connectivity Analysis of Peptides Bearing Two Intramolecular Disulfide Bonds Using MALDI In-Source Decay
P. Massonnet, Jean R. N. Haler, G. Upert, Nicolas Smargiasso +4 more
2018Journal of the American Society for Mass Spectrometry8 citations Open access
Semantic Scholar
High-throughput production of two disulphide-bridge toxins.
G. Upert, G. Mourier, Alexandra Pastor, M. Verdenaud +3 more
2014Chemical Communications7 citations
Semantic Scholar
Effects of ρ‐Da1a a peptidic α1A‐adrenoceptor antagonist in human isolated prostatic adenoma and anaesthetized rats
S. Palea, Arhamatoulaye Maïga, Veronique Guilloteau, M. Rekik +7 more
2013British Journal of Pharmacology7 citations Open access
Semantic Scholar
Can IM-MS Collision Cross Sections of Biomolecules Be Rationalized Using Collision Cross-Section Trends of Polydisperse Synthetic Homopolymers?
Jean R. N. Haler, P. Massonnet, J. Far, G. Upert +4 more
2020Journal of the American Society for Mass Spectrometry6 citations
Semantic Scholar
Changes in vibrational properties of coated wood through ti me from application of varnish, with recipes used in European or Iranian string instruments making
I. Brémaud, E. Karami, S. Bardet, N. Gilles +3 more
20164 citations
Semantic Scholar
Mass-spectrometry-based method for screening of new peptide ligands for G-protein-coupled receptors
C. Cologna, N. Gilles, Julien Echterbille, M. Degueldre +3 more
2015Analytical and Bioanalytical Chemistry4 citations
Semantic Scholar

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E. De Pauw×19
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D. Servent×18
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G. Mourier×17
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M. Gurevitz×11

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Izhar Karbat×9

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Izhar Karbat — researcher profile on SciRah

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N. Ilan — researcher profile on SciRah

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M. Degueldre — researcher profile on SciRah

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