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I-Cheng Chen · SciRah

Researcher profile · Semantic Scholar

I-Cheng Chen

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I-Cheng Chen — researcher profile on SciRah

h-index: 15
Works: 34
Citations: 607

Most-cited papers

Hepatoprotective effects of Arctium lappa Linne on liver injuries induced by chronic ethanol consumption and potentiated by carbon tetrachloride.
Song-Chow Lin, Chia-Hsien Lin, Chun-Ching Lin, Yun-ho Lin +3 more
2002Journal of Biomedical Sciences101 citations
Semantic Scholar
Formulated Chinese Medicine Shaoyao Gancao Tang Reduces Tau Aggregation and Exerts Neuroprotection through Anti-Oxidation and Anti-Inflammation
I-Cheng Chen, Te-Hsien Lin, Yu-Hsuan Hsieh, Chih-Ying Chao +5 more
2018Oxidative Medicine and Cellular Longevity43 citations Open access
Semantic Scholar
Impairment of proteasome and anti-oxidative pathways in the induced pluripotent stem cell model for sporadic Parkinson's disease.
Kuo-Hsuan Chang, G. Lee-Chen, Yih-Ru Wu, Yi-Jing Chen +6 more
2016Parkinsonism & Related Disorders40 citations
Semantic Scholar
Aqueous extract of Glycyrrhiza inflata inhibits aggregation by upregulating PPARGC1A and NFE2L2-ARE pathways in cell models of spinocerebellar ataxia 3.
Chiung-Mei Chen, Yu-Ting Weng, Wan-ling Chen, Te-Hsien Lin +12 more
2014Free Radical Biology & Medicine40 citations
Semantic Scholar
Temporally controlled modulation of FGF/ERK signaling directs midbrain dopaminergic neural progenitor fate in mouse and human pluripotent stem cells
Ines Jaeger, C. Arber, Jessica R. Risner-Janiczek, Judit Kuechler +5 more
2011Development40 citations Open access
Semantic Scholar
Spinocerebellar ataxia type 8 larger triplet expansion alters histone modification and induces RNA foci
I-Cheng Chen, Hsuan-Yuan Lin, Ghin-Chueh Lee, S. Kao +5 more
2009BMC Molecular Biology29 citations Open access
Semantic Scholar
Nuclear receptor NR4A2 IVS6 +18insG and brain derived neurotrophic factor (BDNF) V66M polymorphisms and risk of Taiwanese parkinson's disease
Chiung-Mei Chen, I-Cheng Chen, Kuo-Hsuan Chang, Yi-Chun Chen +6 more
2007American Journal of Medical Genetics Part B: Neuropsychiatric Genetics29 citations
Semantic Scholar
ATP13A2 variability in Taiwanese Parkinson's disease
Chiung-Mei Chen, Chih-Hsin Lin, H. Juan, Fen-Ju Hu +10 more
2011American Journal of Medical Genetics Part B: Neuropsychiatric Genetics26 citations Open access
Semantic Scholar
Novel Lactulose and Melibiose Targeting Autophagy to Reduce PolyQ Aggregation in Cell Models of Spinocerebellar Ataxia 3.
Chih-Hsin Lin, Yih-Ru Wu, Jinn-Moon Yang, Wan-ling Chen +10 more
2016CNS and Neurological Disorders - Drug Targets25 citations
Semantic Scholar
Hepatoprotective Effects of Arctium lappa Linne on Liver Injuries Induced by Chronic Ethanol Consumption and Potentiated by Carbon Tetrachloride
Song-Chow Lin, Chia-Hsien Lin, Chun-Ching Lin, Yun-ho Lin +3 more
2002Journal of Biomedical Sciences25 citations
Semantic Scholar
The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of Alzheimer’s disease
Kuo-Hsuan Chang, I-Cheng Chen, Hsuan-Yuan Lin, hsuan-chiang chen +8 more
2016Drug Design, Development and Therapy24 citations Open access
Semantic Scholar
Shaoyao Gancao Tang (SG-Tang), a formulated Chinese medicine, reduces aggregation and exerts neuroprotection in spinocerebellar ataxia type 17 (SCA17) cell and mouse models
Chiung-Mei Chen, Wan-ling Chen, Chen-Ting Hung, Te-Hsien Lin +8 more
2019Aging22 citations Open access
Semantic Scholar
FBXO7 Y52C Polymorphism as a Potential Protective Factor in Parkinson's Disease
Chiung-Mei Chen, I-Cheng Chen, Yi-Cheng Huang, H. Juan +8 more
2014PLoS ONE18 citations Open access
Semantic Scholar
Targeting Ubiquitin Proteasome Pathway with Traditional Chinese Medicine for Treatment of Spinocerebellar Ataxia Type 3.
I-Cheng Chen, Chia-ning Chang, Wan-ling Chen, Te-Hsien Lin +9 more
2019The American Journal of Chinese Medicine15 citations
Semantic Scholar
SCA8 repeat expansion: large CTA/CTG repeat alleles in neurological disorders and functional implications
Yih-Ru Wu, I-Cheng Chen, B. Soong, S. Kao +5 more
2009Human Genetics15 citations
Semantic Scholar
α-Synuclein promoter RsaI T-to-C polymorphism and the risk of Parkinson’s disease
C.-K. Wang, C.-M. Chen, C. Y. Chang, K. Chang +4 more
2006Journal of neural transmission15 citations
Semantic Scholar
Pueraria lobata and Daidzein Reduce Cytotoxicity by Enhancing Ubiquitin-Proteasome System Function in SCA3-iPSC-Derived Neurons
I-Cheng Chen, Kuo-Hsuan Chang, Yi-Jing Chen, Yi-Chun Chen +2 more
2019Oxidative Medicine and Cellular Longevity13 citations Open access
Semantic Scholar
alpha-Synuclein promoter RsaI T-to-C polymorphism and the risk of Parkinson's disease.
C.-K. Wang, C.-M. Chen, C. Y. Chang, K. Chang +4 more
2006Journal of neural transmission11 citations
Semantic Scholar
First report of two Taiwanese siblings with sialidosis type I: a 10-year follow-up study.
Chiung-Mei Chen, S. Lai, I-Cheng Chen, Kai-Cheng Hsu +3 more
2006Journal of Neurological Sciences11 citations
Semantic Scholar
Expanded trinucleotide repeats in the TBP/SCA17 gene mapped to chromosome 6q27 are associated with schizophrenia.
Chiung-Mei Chen, Hsien-Yuan Lane, Yih-Ru Wu, L. Ro +11 more
2005Schizophrenia Research11 citations
Semantic Scholar
Medicinal herbs Oenanthe javanica (Blume) DC., Casuarina equisetifolia L. and Sorghum bicolor (L.) Moench protect human cells from MPP+ damage via inducing FBXO7 expression.
Chiung-Mei Chen, I-Cheng Chen, Ying-Lin Chen, Te-Hsien Lin +9 more
2016Phytomedicine8 citations
Semantic Scholar
HTRA2 variations in Taiwanese Parkinson’s disease
Chiung-Mei Chen, C. Wu, C.-H. Hsieh, Chih-Hsin Lin +7 more
2013Journal of neural transmission8 citations
Semantic Scholar
Dissecting the all-hermaphrodite phenomenon of a rare X chromosome mutant in papaya (Carica papaya L.)
Jen-Ren Chen, N. Urasaki, H. Matsumura, I-Cheng Chen +4 more
2019Molecular breeding7 citations
Semantic Scholar
Investigating the therapeutic effects of novel compounds targeting inflammatory IL-1β and IL-6 signaling pathways in spinocerebellar ataxia type 3.
I-Cheng Chen, Wan-ling Chen, Kuo-Hsuan Chang, Jun-Wei Lee +4 more
2024European Journal of Pharmacology6 citations Open access
Semantic Scholar
Internal Ribosome Entry Segment Activity of ATXN8 Opposite Strand RNA
I-Cheng Chen, Hsuan-Yuan Lin, Ya-Chin Hsiao, Chiung-Mei Chen +7 more
2013PLoS ONE5 citations Open access
Semantic Scholar
ATXN8 −62 G/A promoter polymorphism and risk of Taiwanese Parkinson's disease
I-Cheng Chen, Yih-Ru Wu, S.-J. Yang, S. Kao +5 more
2012European Journal of Neurology5 citations
Semantic Scholar
Small Molecules Inducing Autophagic Degradation of Expanded Polyglutamine Protein through Interaction with Both Mutant ATXN3 and LC3
Te-Hsien Lin, Wan-ling Chen, Shao-Fan Hsu, I-Cheng Chen +8 more
2024International Journal of Molecular Sciences3 citations
Semantic Scholar
Recurrent cerebral venous thrombosis: an Arg359X mutation in the antithrombin gene in a Taiwanese family.
Chiung-Mei Chen, G. Lee-Chen, Yih-Ru Wu, Cheng-Yueh Lin +3 more
2006Thrombosis Research3 citations
Semantic Scholar
The potential of mulberry (Morus alba L.) leaf extract against pro-aggregant tau-mediated inflammation and mitochondrial dysfunction.
Te-Hsien Lin, Pei-Hsuan Tseng, I-Cheng Chen, Chung-Yin Lin +4 more
2025Neurochemistry International1 citations
Semantic Scholar
The aqueous extract of Glycyrrhiza inflata can upregulate unfolded protein response-mediated chaperones to reduce tau misfolding in cell models of alzheimer’s disease
Kuo-Hsuan Chang, I-Cheng Chen, Hsuan-Yuan Lin, hsuan-chiang chen +8 more
20161 citations
Semantic Scholar
Protective effects of three herbal extracts on mitochondrial dysfunction in VPS13C-knockdown SH-SY5Y cells: implications for Parkinson's disease.
Yih-Ru Wu, Chih-Hsin Lin, Pei-Syuan Huang, Chih-Ying Chao +7 more
2026Aging0 citations Open access
Semantic Scholar
Coptis chinensis rhizome extract up-regulates ATP13A2 and lysosomal function to reduce neuronal vulnerability in α-synuclein-expressing BE(2)-M17 cells
Chih-Hsin Lin, Yih-Ru Wu, Chih-Ying Chao, Chiung-Mei Chen +3 more
2026Journal of Traditional and Complementary Medicine0 citations Open access
Semantic Scholar
Studies of Cap Independent Internal Ribosome Entry Segment Activity of ATXN8OS RNA
H. Shiau, I-Cheng Chen, Hsuan-Yuan Lin, Ming-Tsan Su +1 more
20120 citations
Semantic Scholar
SCA 8 repeat expansion : large CTA / CTG repeat alleles in neurological disorders and functional implications
Yih-Ru Wu, I-Cheng Chen, B. Soong, S. Kao +5 more
20090 citations
Semantic Scholar

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G. Lee-Chen×29
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Chiung-Mei Chen×27
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Chiung-Mei Chen — researcher profile on SciRah
Yih-Ru Wu×23
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Yih-Ru Wu — researcher profile on SciRah
Kuo-Hsuan Chang×13
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Te-Hsien Lin — researcher profile on SciRah

Chih-Ying Chao×12

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Chih-Hsin Lin×12

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Wan-ling Chen×8

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Hsuan-Yuan Lin×7

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Li-Ching Lee×4

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Yi-Chun Chen×4

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Jung-Yaw Lin×4

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