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R. Zechner · SciRah

Researcher profile · Semantic Scholar

R. Zechner

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R. Zechner — researcher profile on SciRah

h-index: 88
Works: 265
Citations: 31K

Most-cited papers

A switch from white to brown fat increases energy expenditure in cancer-associated cachexia.
M. Petruzzelli, M. Schweiger, R. Schreiber, R. Campos-Olivas +8 more
2014Cell Metabolism698 citations Open access
Semantic Scholar
Lipolysis: cellular mechanisms for lipid mobilization from fat stores
G. Grabner, Hao Xie, M. Schweiger, R. Zechner
2021Nature Metabolism664 citations Open access
Semantic Scholar
Cytosolic lipolysis and lipophagy: two sides of the same coin
R. Zechner, F. Madeo, D. Kratky
2017Nature reviews. Molecular cell biology502 citations
Semantic Scholar
Cold-Induced Thermogenesis Depends on ATGL-Mediated Lipolysis in Cardiac Muscle, but Not Brown Adipose Tissue
R. Schreiber, C. Diwoky, G. Schoiswohl, Ursula Feiler +9 more
2017Cell Metabolism290 citations Open access
Semantic Scholar
Global analysis of plasma lipids identifies liver-derived acylcarnitines as a fuel source for brown fat thermogenesis
Judith Simcox, Gisela Geoghegan, J. Maschek, Claire L. Bensard +14 more
2017bioRxiv267 citations Open access
Semantic Scholar
Lysosomal Signaling Molecules Regulate Longevity in Caenorhabditis elegans
Andrew Folick, H. Oakley, Yong Yu, E. Armstrong +6 more
2015Science262 citations Open access
Semantic Scholar
Pharmacological inhibition of adipose triglyceride lipase corrects high-fat diet-induced insulin resistance and hepatosteatosis in mice
M. Schweiger, M. Romauch, R. Schreiber, G. Grabner +13 more
2017Nature Communications209 citations Open access
Semantic Scholar
Measurement of Lipolysis
M. Schweiger, Thomas O. Eichmann, Ulrike Taschler, R. Zimmermann +2 more
2014Methods in Enzymology176 citations Open access
Semantic Scholar
Brown adipose tissue whitening leads to brown adipocyte death and adipose tissue inflammation[S]
P. Kotzbeck, A. Giordano, E. Mondini, I. Murano +8 more
2018Journal of Lipid Research155 citations Open access
Semantic Scholar
Lipolysis Triggers a Systemic Insulin Response Essential for Efficient Energy Replenishment of Activated Brown Adipose Tissue in Mice.
M. Heine, Alexander W. Fischer, C. Schlein, C. Jung +11 more
2018Cell Metabolism152 citations Open access
Semantic Scholar
Analysis of acetylation stoichiometry suggests that SIRT3 repairs nonenzymatic acetylation lesions
B. Weinert, T. Moustafa, V. Iesmantavicius, R. Zechner +1 more
2015EMBO Journal141 citations Open access
Semantic Scholar
Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Olivia Sveidahl Johansen, Tao Ma, J. Hansen, Lasse K. Markussen +47 more
2021Cell121 citations Open access
Semantic Scholar
ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids
Rucha A. Patel, A. Santoro, Peter Hofer, Dan Tan +7 more
2022Nature120 citations Open access
Semantic Scholar
Fat-specific Protein 27 (FSP27) Interacts with Adipose Triglyceride Lipase (ATGL) to Regulate Lipolysis and Insulin Sensitivity in Human Adipocytes*
T. Grahn, R. Kaur, Jun-Yi Yin, M. Schweiger +7 more
2014Journal of Biological Chemistry114 citations Open access
Semantic Scholar
Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia
Pooja Jha, T. Claudel, A. Baghdasaryan, Michaela Mueller +7 more
2014Hepatology96 citations Open access
Semantic Scholar
PNPLA1 Deficiency in Mice and Humans Leads to a Defect in the Synthesis of Omega-O-Acylceramides
S. Grond, Thomas O. Eichmann, S. Dubrac, D. Kolb +8 more
2016Journal of Investigative Dermatology90 citations Open access
Semantic Scholar
The Interplay of Protein Kinase A and Perilipin 5 Regulates Cardiac Lipolysis*♦
N. Pollak, Doris Jaeger, Stephanie Kolleritsch, R. Zimmermann +3 more
2014Journal of Biological Chemistry90 citations Open access
Semantic Scholar
CD8+ T cells induce cachexia during chronic viral infection
Hatoon Baazim, M. Schweiger, Michael Moschinger, Hai-Feng C. Xu +17 more
2019Nature Immunology87 citations Open access
Semantic Scholar
Depletion of White Adipose Tissue in Cancer Cachexia Syndrome Is Associated with Inflammatory Signaling and Disrupted Circadian Regulation
M. Tsoli, M. Schweiger, A. Vanniasinghe, Arran Painter +3 more
2014PLoS ONE87 citations Open access
Semantic Scholar
Distinct roles of adipose triglyceride lipase and hormone-sensitive lipase in the catabolism of triacylglycerol estolides
K. Brejchova, Franz P. W. Radner, L. Balas, V. Paluchová +8 more
2020Proceedings of the National Academy of Sciences of the United States of America77 citations Open access
Semantic Scholar
Hypoxia-inducible Lipid Droplet-associated (HILPDA) Is a Novel Peroxisome Proliferator-activated Receptor (PPAR) Target Involved in Hepatic Triglyceride Secretion*
F. Mattijssen, A. Georgiadi, Tresty Andasarie, E. Szalowska +9 more
2014Journal of Biological Chemistry73 citations Open access
Semantic Scholar
An immune-sympathetic neuron communication axis guides adipose tissue browning in cancer-associated cachexia
Hao Xie, Christoph Heier, Xia Meng, L. Bakiri +13 more
2022Proceedings of the National Academy of Sciences of the United States of America72 citations Open access
Semantic Scholar
Hypoxia-inducible lipid droplet-associated protein inhibits adipose triglyceride lipase
K. M. Padmanabha Das, L. Wechselberger, Márton Liziczai, M. A. de la Rosa Rodriguez +10 more
2018Journal of Lipid Research72 citations Open access
Semantic Scholar
Hypophagia and metabolic adaptations in mice with defective ATGL-mediated lipolysis cause resistance to HFD-induced obesity
R. Schreiber, Peter Hofer, Ulrike Taschler, P. Voshol +10 more
2015Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
Loss of adipose triglyceride lipase is associated with human cancer and induces mouse pulmonary neoplasia
W. Al-Zoughbi, M. Pichler, G. Gorkiewicz, B. Guertl-Lackner +15 more
2016OncoTarget67 citations Open access
Semantic Scholar
The Role of Adipose Triglyceride Lipase and Cytosolic Lipolysis in Cardiac Function and Heart Failure
U. Kintscher, A. Foryst-Ludwig, G. Haemmerle, R. Zechner
2020Cell Reports Medicine61 citations Open access
Semantic Scholar
Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis
Manoja K. Brahma, Rene C. Adam, N. Pollak, Doris Jaeger +11 more
2014Journal of Lipid Research61 citations Open access
Semantic Scholar
Interleukin‐6 initiates muscle‐ and adipose tissue wasting in a novel C57BL/6 model of cancer‐associated cachexia
Isabella Pototschnig, Ursula Feiler, C. Diwoky, Paul W. Vesely +15 more
2022Journal of Cachexia, Sarcopenia and Muscle59 citations Open access
Semantic Scholar
Lipokine 5-PAHSA Is Regulated by Adipose Triglyceride Lipase and Primes Adipocytes for De Novo Lipogenesis in Mice
V. Paluchová, M. Oseeva, Marie Brezinova, T. Cajka +14 more
2019Diabetes58 citations Open access
Semantic Scholar
FAT FLUX: enzymes, regulators, and pathophysiology of intracellular lipolysis
R. Zechner
2015EMBO Molecular Medicine57 citations Open access
Semantic Scholar
Adipose triglyceride lipase activity is inhibited by long-chain acyl-coenzyme A
H. M. Nagy, Margret Paar, Christoph Heier, T. Moustafa +6 more
2014Biochimica et Biophysica Acta56 citations Open access
Semantic Scholar
Fatty Acid-binding Proteins Interact with Comparative Gene Identification-58 Linking Lipolysis with Lipid Ligand Shuttling
Peter Hofer, A. Boeszoermenyi, Doris Jaeger, Ursula Feiler +11 more
2015Journal of Biological Chemistry53 citations Open access
Semantic Scholar
Fasting-induced G0/G1 switch gene 2 and FGF21 expression in the liver are under regulation of adipose tissue derived fatty acids
Doris Jaeger, G. Schoiswohl, Peter Hofer, R. Schreiber +14 more
2015Journal of Hepatology53 citations Open access
Semantic Scholar
Adipose triglyceride lipase is involved in the mobilization of triglyceride and retinoid stores of hepatic stellate cells
Ulrike Taschler, R. Schreiber, Chandramohan Chitraju, G. Grabner +7 more
2015Biochimica et Biophysica Acta52 citations Open access
Semantic Scholar
Adipose triglyceride lipase activity regulates cancer cell proliferation via AMP-kinase and mTOR signaling
Hao Xie, Christoph Heier, Benedikt Kien, P. Vesely +7 more
2020Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids46 citations Open access
Semantic Scholar
CGI-58’S ABILITY TO REGULATE HEPATIC TRIACYLGLYCEROL METABOLISM DOES NOT REQUIRE ATGL CO-ACTIVATION
C. Lord, D. Ferguson, G. Thomas, Amanda L. Brown +18 more
2016Cell Reports46 citations Open access
Semantic Scholar
Lysosomal Acid Lipase Hydrolyzes Retinyl Ester and Affects Retinoid Turnover
L. Grumet, Thomas O. Eichmann, Ulrike Taschler, Kathrin A. Zierler +12 more
2016Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Structure of a CGI-58 Motif Provides the Molecular Basis of Lipid Droplet Anchoring
A. Boeszoermenyi, H. M. Nagy, H. Arthanari, C. Pillip +6 more
2015Journal of Biological Chemistry45 citations Open access
Semantic Scholar
Effects of bezafibrate treatment in a patient and a carrier with mutations in the PNPLA2 gene, causing neutral lipid storage disease with myopathy.
T. van de Weijer, B. Havekes, L. Bilet, J. Hoeks +13 more
2013Circulation Research45 citations Open access
Semantic Scholar
Small-Molecule Inhibitors Targeting Lipolysis in Human Adipocytes
G. Grabner, Nikolaus Guttenberger, Nicole Mayer, Anna K Migglautsch-Sulzer +18 more
2022Journal of the American Chemical Society44 citations Open access
Semantic Scholar
Metabolic disease and ABHD6 alter the circulating bis(monoacylglycerol)phosphate profile in mice and humans
G. Grabner, Nermeen Fawzy, Maria A. Pribasnig, M. Trieb +18 more
2019Journal of Lipid Research43 citations Open access
Semantic Scholar
Adipose triglyceride lipase and comparative gene identification-58 are lipid droplet proteins of the hepatic stellate cell-line HSC-T6
Thomas O. Eichmann, L. Grumet, Ulrike Taschler, J. Hartler +10 more
2015Journal of Lipid Research41 citations Open access
Semantic Scholar
A Peptide Derived from G0/G1 Switch Gene 2 Acts as Noncompetitive Inhibitor of Adipose Triglyceride Lipase
I. Cerk, Barbara Salzburger, A. Boeszoermenyi, Christoph Heier +8 more
2014Journal of Biological Chemistry40 citations Open access
Semantic Scholar
The Hepatitis C Virus Core Protein Inhibits Adipose Triglyceride Lipase (ATGL)-mediated Lipid Mobilization and Enhances the ATGL Interaction with Comparative Gene Identification 58 (CGI-58) and Lipid Droplets*
G. Camus, M. Schweiger, E. Herker, C. Harris +9 more
2014Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Pharmacological inhibition of adipose tissue Adipose Triglyceride Lipase (ATGL) by Atglistatin prevents catecholamine-induced myocardial damage.
Arne Thiele, Katja Luettges, D. Ritter, N. Beyhoff +15 more
2021Cardiovascular Research37 citations Open access
Semantic Scholar
Liver X receptor α mediates hepatic triglyceride accumulation through upregulation of G0/G1 Switch Gene 2 expression.
Bradlee L. Heckmann, Xiao-Dong Zhang, Alicia M. Saarinen, G. Schoiswohl +3 more
2017JCI Insight36 citations Open access
Semantic Scholar
Endothelial dysfunction in adipose triglyceride lipase deficiency
A. Schrammel, Marion Mussbacher, G. Wölkart, H. Stessel +9 more
2014Biochimica et Biophysica Acta35 citations Open access
Semantic Scholar
Micro RNA-124a Regulates Lipolysis via Adipose Triglyceride Lipase and Comparative Gene Identification 58
S. Das, Elke Stadelmeyer, S. Schauer, Anna Schwarz +5 more
2015International Journal of Molecular Sciences34 citations Open access
Semantic Scholar
G0/G1 Switch Gene 2 Regulates Cardiac Lipolysis*
Christoph Heier, F. Radner, T. Moustafa, R. Schreiber +11 more
2015Journal of Biological Chemistry33 citations Open access
Semantic Scholar
Enhanced monoacylglycerol lipolysis by ABHD6 promotes NSCLC pathogenesis
Zhi-Yuan Tang, Hao Xie, Christoph Heier, Jian-Fei Huang +7 more
2020EBioMedicine32 citations Open access
Semantic Scholar

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