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K. Kurakula · SciRah

Researcher profile · Semantic Scholar

K. Kurakula

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K. Kurakula — researcher profile on SciRah

h-index: 24
Works: 70
Citations: 1,905

Most-cited papers

Bone Marrow–Specific Deficiency of Nuclear Receptor Nur77 Enhances Atherosclerosis
AAJ Hamers, M. Vos, F. Rassam, G. Marinković +6 more
2012Circulation Research192 citations Open access
Semantic Scholar
NR4A nuclear receptors are orphans but not lonesome.
K. Kurakula, D. Koenis, C. V. van Tiel, C. D. de Vries
2014Biochimica et Biophysica Acta149 citations Open access
Semantic Scholar
Endothelial Dysfunction in Pulmonary Hypertension: Cause or Consequence?
K. Kurakula, V. Smolders, O. Tura-Ceide, J. Jukema +2 more
2021Biomedicines129 citations Open access
Semantic Scholar
Cellular senescence impairs the reversibility of pulmonary arterial hypertension
D. E. van der Feen, Guido P. L. Bossers, Q. Hagdorn, J. Moonen +16 more
2020Science Translational Medicine123 citations Open access
Semantic Scholar
Multicenter Preclinical Validation of BET Inhibition for the Treatment of Pulmonary Arterial Hypertension.
D. E. van der Feen, K. Kurakula, È. Tremblay, O. Boucherat +16 more
2019American Journal of Respiratory and Critical Care Medicine121 citations Open access
Semantic Scholar
TGF-β and BMPR2 Signaling in PAH: Two Black Sheep in One Family
N. Rol, K. Kurakula, C. Happé, H. Bogaard +1 more
2018International Journal of Molecular Sciences106 citations Open access
Semantic Scholar
Contribution of Impaired Parasympathetic Activity to Right Ventricular Dysfunction and Pulmonary Vascular Remodeling in Pulmonary Arterial Hypertension
Gonçalves Bos Denielli da Silva, Cathelijne E. E. van der Bruggen, K. Kurakula, Xiao-Qing Sun +17 more
2017Circulation98 citations Open access
Semantic Scholar
Cardiac endothelial cells express Wilms' tumor-1: Wt1 expression in the developing, adult and infarcted heart.
S. Duim, K. Kurakula, M. Goumans, B. Kruithof
2015Journal of Molecular and Cellular Cardiology96 citations
Semantic Scholar
Protein-protein interactions of the LIM-only protein FHL2 and functional implication of the interactions relevant in cardiovascular disease.
M. Tran, K. Kurakula, D. Koenis, C. D. de Vries
2016Biochimica et Biophysica Acta70 citations Open access
Semantic Scholar
Nuclear Receptor Nur77 Attenuates Airway Inflammation in Mice by Suppressing NF-κB Activity in Lung Epithelial Cells
K. Kurakula, M. Vos, A. Logiantara, J. Roelofs +5 more
2015Journal of Immunology69 citations Open access
Semantic Scholar
Autophagy contributes to BMP type 2 receptor degradation and development of pulmonary arterial hypertension
M. C. Gomez-Puerto, Iris van Zuijen, Christopher J. Z. Huang, R. Szulcek +9 more
2019Journal of Pathology49 citations Open access
Semantic Scholar
FHL2 Protein Is a Novel Co-repressor of Nuclear Receptor Nur77*
K. Kurakula, E. van der Wal, Dirk Geerts, C. V. van Tiel +1 more
2011Journal of Biological Chemistry47 citations Open access
Semantic Scholar
Inhibition of GTPase Rac1 in Endothelium by 6-Mercaptopurine Results in Immunosuppression in Nonimmune Cells: New Target for an Old Drug
G. Marinković, J. Kroon, M. Hoogenboezem, K. Hoeben +7 more
2014Journal of Immunology46 citations Open access
Semantic Scholar
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension
N. Rol, M. D. de Raaf, Xiao-Qing Sun, Vincent P Kuiper +19 more
2018Cardiovascular Research45 citations Open access
Semantic Scholar
Thoracic Aortic Aneurysm Development in Patients with Bicuspid Aortic Valve: What Is the Role of Endothelial Cells?
V. van de Pol, K. Kurakula, M. DeRuiter, M. Goumans
2017Frontiers in Physiology38 citations Open access
Semantic Scholar
Exacerbated inflammatory signaling underlies aberrant response to BMP9 in pulmonary arterial hypertension lung endothelial cells
R. Szulcek, G. Sánchez-Duffhues, N. Rol, Xiao-Ke Pan +11 more
2020Angiogenesis36 citations Open access
Semantic Scholar
The Inflammatory Profile of CTEPH-Derived Endothelial Cells Is a Possible Driver of Disease Progression
V. Smolders, K. Lodder, C. Rodríguez, O. Tura-Ceide +5 more
2021Cells33 citations Open access
Semantic Scholar
6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFκB activation in airway epithelial cells
K. Kurakula, AAJ Hamers, P. V. van Loenen, C. D. de Vries
2015Respiratory Research33 citations Open access
Semantic Scholar
Endothelial dysfunction in pulmonary arterial hypertension: loss of cilia length regulation upon cytokine stimulation
Anneloes Dummer, N. Rol, R. Szulcek, K. Kurakula +6 more
2018Pulmonary Circulation31 citations Open access
Semantic Scholar
Dual function of Pin1 in NR4A nuclear receptor activation: enhanced activity of NR4As and increased Nur77 protein stability.
C. V. van Tiel, K. Kurakula, D. Koenis, E. van der Wal +1 more
2012Biochimica et Biophysica Acta30 citations Open access
Semantic Scholar
Altered TGFβ/SMAD Signaling in Human and Rat Models of Pulmonary Hypertension: An Old Target Needs Attention
T. Sanada, Xiao-Qing Sun, C. Happé, C. Guignabert +5 more
2021Cells27 citations Open access
Semantic Scholar
The BMP Receptor 2 in Pulmonary Arterial Hypertension: When and Where the Animal Model Matches the Patient
C. Happé, K. Kurakula, Xiao-Qing Sun, Gonçalves Bos Denielli da Silva +10 more
2020Cells27 citations Open access
Semantic Scholar
Prevention of progression of pulmonary hypertension by the Nur77 agonist 6-mercaptopurine: role of BMP signalling
K. Kurakula, Xiao-Qing Sun, C. Happé, Gonçalves Bos Denielli da Silva +12 more
2019European Respiratory Journal25 citations Open access
Semantic Scholar
Derivation and characterisation of endothelial cells from patients with chronic thromboembolic pulmonary hypertension
O. Tura-Ceide, V. Smolders, Núria Aventín, C. Morén +14 more
2021Scientific Reports24 citations Open access
Semantic Scholar
The LIM-Only Protein FHL2 Reduces Vascular Lesion Formation Involving Inhibition of Proliferation and Migration of Smooth Muscle Cells
K. Kurakula, M. Vos, Iker Otermin Rubio, G. Marinković +6 more
2014PLoS ONE24 citations Open access
Semantic Scholar
LIM-Only Protein FHL2 Is a Positive Regulator of Liver X Receptors in Smooth Muscle Cells Involved in Lipid Homeostasis
K. Kurakula, Daniela Sommer, M. Sokolović, P. Moerland +6 more
2014Molecular and Cellular Biology23 citations Open access
Semantic Scholar
Nuclear Receptors in atherosclerosis: a superfamily with many 'Goodfellas'.
K. Kurakula, AAJ Hamers, V. de Waard, C. D. de Vries
2013Molecular and Cellular Endocrinology23 citations
Semantic Scholar
Increased MAO-A Activity Promotes Progression of Pulmonary Arterial Hypertension.
Xiao-Qing Sun, E. Peters, I. Schalij, Julie Birkmose Axelsen +13 more
2020American Journal of Respiratory Cell and Molecular Biology21 citations
Semantic Scholar
Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of Tissue Factor gene expression, protein half-life, and pro-coagulant activity
K. Kurakula, D. Koenis, M. Herzik, Yanyun Liu +9 more
2018Haematologica19 citations Open access
Semantic Scholar
Regulatory RNAs controlling vascular (dys)function by affecting TGF-ß family signalling
K. Kurakula, M. Goumans, P. ten Dijke
2015EXCLI Journal : Experimental and Clinical Sciences17 citations
Semantic Scholar
LIM-only protein FHL2 attenuates inflammation in vascular smooth muscle cells through inhibition of the NFκB pathway.
V. van de Pol, M. Vos, M. DeRuiter, M. Goumans +2 more
2019Vascular pharmacology16 citations Open access
Semantic Scholar
Deficiency of FHL2 attenuates airway inflammation in mice and genetic variation associates with human bronchial hyper‐responsiveness
K. Kurakula, M. Vos, A. Logiantara, J. Roelofs +9 more
2015Allergy. European Journal of Allergy and Clinical Immunology15 citations Open access
Semantic Scholar
Inhibition of the prolyl isomerase Pin1 improves endothelial function and attenuates vascular remodelling in pulmonary hypertension by inhibiting TGF-β signalling
K. Kurakula, Q. Hagdorn, D. E. van der Feen, Anton Vonk Noordegraaf +5 more
2021Angiogenesis14 citations Open access
Semantic Scholar
LIM‐only protein FHL2 regulates experimental pulmonary Schistosoma mansoni egg granuloma formation
K. Kurakula, M. Vos, M. van Eijk, H. Smits +1 more
2015European Journal of Immunology12 citations Open access
Semantic Scholar
Sex Dimorphism in Pulmonary Arterial Hypertension Associated With Autoimmune Diseases
A. Krzyżewska, K. Kurakula
2024Arteriosclerosis, Thrombosis and Vascular Biology11 citations Open access
Semantic Scholar
The Effects of Mercaptopurine on Pulmonary Vascular Resistance and BMPR2 Expression in Pulmonary Arterial Hypertension.
L. Botros, R. Szulcek, S. Jansen, K. Kurakula +6 more
2020American Journal of Respiratory and Critical Care Medicine11 citations Open access
Semantic Scholar
Volume Load-Induced Right Ventricular Failure in Rats Is Not Associated With Myocardial Fibrosis
Q. Hagdorn, K. Kurakula, A. Koop, Guido P. L. Bossers +6 more
2021Frontiers in Physiology9 citations Open access
Semantic Scholar
Endothelial Colony Forming Cells as an Autologous Model to Study Endothelial Dysfunction in Patients with a Bicuspid Aortic Valve
V. van de Pol, L. Bons, K. Lodder, K. Kurakula +5 more
2019International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Effects of 6-mercaptopurine in pressure overload induced right heart failure
Julie Birkmose Axelsen, S. Andersen, Xiao-Qing Sun, S. Ringgaard +7 more
2019PLoS ONE8 citations Open access
Semantic Scholar
6-mercaptopurine, an agonist of Nur77, reduces progression of pulmonary hypertension by enhancing BMP signalling
K. Kurakula, Xiao-Qing Sun, C. Happé, Gonçalves Bos Denielli da Silva +14 more
20198 citations
Semantic Scholar
Angiogenesis in Chronic Thromboembolic Pulmonary Hypertension: A Janus-Faced Player?
Lynn Willems, K. Kurakula, Janne Verhaegen, F. Klok +3 more
2024Arteriosclerosis, Thrombosis and Vascular Biology7 citations Open access
Semantic Scholar
The Interplay Between Pulmonary Hypertension and Atrial Fibrillation: A Comprehensive Overview
Danish Sultan, B. Brundel, K. Kurakula
2025Cells4 citations Open access
Semantic Scholar
LIM-only protein FHL2 attenuates vascular tissue factor activity, inhibits thrombus formation in mice and FHL2 genetic variation associates with human venous thrombosis
C. Kroone, M. Vos, T. Rademakers, M. Kuijpers +9 more
2019Haematologica4 citations Open access
Semantic Scholar
BMP Receptor Inhibition Enhances Tissue Repair in Endoglin Heterozygous Mice
W. Bakker, Calinda K E Dingenouts, K. Lodder, K. Wiesmeijer +7 more
2021International Journal of Molecular Sciences3 citations Open access
Semantic Scholar
Imaging the TGFβ type I receptor in pulmonary arterial hypertension
L. Rotteveel, A. Poot, E. Kooijman, R. Schuit +9 more
2023EJNMMI Research2 citations Open access
Semantic Scholar
Selective inhibition of Histone deacetylases reverses vascular remodelling and improves right ventricle function in pulmonary hypertension
K. Kurakula, X. Sun, D. E. van der Feen, Q. Hagdorn +3 more
2020European Heart Journal2 citations
Semantic Scholar
Selective inhibition of Histone deacetylases reverses vascular remodeling and improves right ventricle function in pulmonary hypertension
K. Kurakula, Xiao-Qing Sun, S. Bonnet, Rolf M. F. Berger +2 more
2023Pulmonary hypertension1 citations
Semantic Scholar
Synthesis and preclinical evaluation of [11C]LR111 and [18F]EW-7197 as PET tracers of the activin-receptor like kinase-5.
L. Rotteveel, K. Kurakula, E. Kooijman, R. Schuit +9 more
2022Nuclear Medicine and Biology1 citations Open access
Semantic Scholar
The effect of 6-mercaptopurine treatment on experimentally induced pulmonary arterial hypertension
Xiao-Qing Sun, K. Kurakula, C. Happé, Gonçalves Bos Denielli da Silva +5 more
20171 citations
Semantic Scholar
FHL2 is a novel target in pulmonary arterial hypertension
C. Nadeem, D. Pérez, C. D. de Vries, K. Kurakula
2025Pulmonary hypertension0 citations
Semantic Scholar

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