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Shih-Hsin Tu · SciRah

Researcher profile · Semantic Scholar

Shih-Hsin Tu

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Shih-Hsin Tu — researcher profile on SciRah

h-index: 24
Works: 79
Citations: 2,070

Most-cited papers

Overexpression and activation of the alpha9-nicotinic receptor during tumorigenesis in human breast epithelial cells.
Chia-Hwa Lee, Ching-Shui Huang, Ching-Shyang Chen, Shih-Hsin Tu +9 more
2010Journal of the National Cancer Institute179 citations
Semantic Scholar
Increased expression of enolase α in human breast cancer confers tamoxifen resistance in human breast cancer cells
Shih-Hsin Tu, Chih-Chiang Chang, Ching-Shyang Chen, Ka-Wai Tam +11 more
2010Breast Cancer Research and Treatment129 citations
Semantic Scholar
Nicotine-induced human breast cancer cell proliferation attenuated by garcinol through down-regulation of the nicotinic receptor and cyclin D3 proteins
Ching-Shyang Chen, Chia-Hwa Lee, C. Hsieh, Chi-Tang Ho +10 more
2010Breast Cancer Research and Treatment118 citations
Semantic Scholar
Membrane protein-regulated networks across human cancers
Chun-Yu Lin, Chia-Hwa Lee, Yi-Hsuan Chuang, Jung-Yu Lee +10 more
2019Nature Communications104 citations Open access
Semantic Scholar
Crosstalk between nicotine and estrogen-induced estrogen receptor activation induces α9-nicotinic acetylcholine receptor expression in human breast cancer cells
Chia-Hwa Lee, Ya-Chieh Chang, Ching-Shyang Chen, Shih-Hsin Tu +9 more
2011Breast Cancer Research and Treatment88 citations
Semantic Scholar
Tea polyphenol (-)-epigallocatechin-3-gallate inhibits nicotine- and estrogen-induced α9-nicotinic acetylcholine receptor upregulation in human breast cancer cells.
Shih-Hsin Tu, Chung-Yu Ku, Chi-Tang Ho, Ching-Shyang Chen +10 more
2011Molecular Nutrition & Food Research86 citations
Semantic Scholar
Apple Polyphenol Phloretin Inhibits Colorectal Cancer Cell Growth via Inhibition of the Type 2 Glucose Transporter and Activation of p53-Mediated Signaling.
Sheng-Tsai Lin, Shih-Hsin Tu, Po-Sheng Yang, S. Hsu +6 more
2016Journal of Agricultural and Food Chemistry85 citations
Semantic Scholar
An apple a day to prevent cancer formation: Reducing cancer risk with flavonoids
Shih-Hsin Tu, Li-Ching Chen, Y. Ho
2016Journal of Food and Drug Analysis85 citations Open access
Semantic Scholar
Skp2-mediated RagA ubiquitination elicits a negative feedback to prevent amino acid-dependent mTORC1 hyperactivation by recruiting GATOR1
G. Jin, Szu-Wei Lee, Xian Zhang, Zhen-Xin Cai +16 more
2015Molecules and Cells84 citations Open access
Semantic Scholar
Concurrent Gene Signatures for Han Chinese Breast Cancers
Chi-Cheng Huang, Shih-Hsin Tu, Heng-Hui Lien, J. Jeng +4 more
2013PLoS ONE80 citations Open access
Semantic Scholar
Human breast cancer cell metastasis is attenuated by lysyl oxidase inhibitors through down-regulation of focal adhesion kinase and the paxillin-signaling pathway
Li-Ching Chen, Shih-Hsin Tu, Ching-Shui Huang, Ching-Shyang Chen +8 more
2012Breast Cancer Research and Treatment63 citations
Semantic Scholar
The α9 Nicotinic Acetylcholine Receptor Mediates Nicotine-Induced PD-L1 Expression and Regulates Melanoma Cell Proliferation and Migration
Hai Nguyen, You-Cheng Liao, Y. Ho, Li-Ching Chen +7 more
2019Cancers57 citations Open access
Semantic Scholar
Down-regulation of α-L-fucosidase 1 expression confers inferior survival for triple-negative breast cancer patients by modulating the glycosylation status of the tumor cell surface
Tzu-Chun Cheng, Shih-Hsin Tu, Li-Ching Chen, Ming-Yao Chen +6 more
2015OncoTarget48 citations Open access
Semantic Scholar
Luteolin sensitises drug-resistant human breast cancer cells to tamoxifen via the inhibition of cyclin E2 expression.
Shih-Hsin Tu, Chi-Tang Ho, Ming-Fang Liu, Ching-Shui Huang +4 more
2013Food Chemistry43 citations
Semantic Scholar
Proteasome 26S Subunit, non-ATPase 3 (PSMD3) Regulates Breast Cancer by Stabilizing HER2 from Degradation
A. Fararjeh, Li-Ching Chen, Y. Ho, Tzu-Chun Cheng +5 more
2019Cancers41 citations Open access
Semantic Scholar
Garcinol sensitizes breast cancer cells to Taxol through the suppression of caspase-3/iPLA2 and NF-κB/Twist1 signaling pathways in a mouse 4T1 breast tumor model.
Shih-Hsin Tu, Yi-shiou Chiou, N. Kalyanam, Chi-Tang Ho +2 more
2017Food & Function41 citations
Semantic Scholar
The learning curve of endoscopic total mastectomy in Taiwan: A multi-center study
Chin-Sheng Hung, Sheng-Wei Chang, Li-Min Liao, Cheng-Chiao Huang +7 more
2017PLoS ONE39 citations Open access
Semantic Scholar
A polygenic risk score for breast cancer risk in a Taiwanese population
Y. Hsieh, Shih-Hsin Tu, Chien-Tien Su, E. Cho +6 more
2017Breast Cancer Research and Treatment37 citations
Semantic Scholar
Changes in quality of life among newly diagnosed breast cancer patients in Taiwan.
Sue-Yueh Cheng, Y. Lai, Shu-Ching Chen, S. Shun +5 more
2012Journal of Clinical Nursing35 citations
Semantic Scholar
DNA primase polypeptide 1 (PRIM1) involves in estrogen‐induced breast cancer formation through activation of the G2/M cell cycle checkpoint
Wei-Hwa Lee, Li-Ching Chen, Chia-Jung Lee, Chi-Cheng Huang +9 more
2018International Journal of Cancer33 citations Open access
Semantic Scholar
In vivo antitumor effects of 4,7-dimethoxy-5-methyl-1,3-benzodioxole isolated from the fruiting body of Antrodia camphorata through activation of the p53-mediated p27/Kip1 signaling pathway.
Shih-Hsin Tu, Chih-Hsiung Wu, Li-Ching Chen, Ching-Shui Huang +4 more
2012Journal of Agricultural and Food Chemistry28 citations
Semantic Scholar
Long-term ethanol exposure-induced hepatocellular carcinoma cell migration and invasion through lysyl oxidase activation are attenuated by combined treatment with pterostilbene and curcumin analogues.
Ching-Shui Huang, Chi-Tang Ho, Shih-Hsin Tu, Min-Hsiung Pan +5 more
2013Journal of Agricultural and Food Chemistry26 citations
Semantic Scholar
Quality of life in Taiwanese breast cancer survivors with breast-conserving therapy.
Chi-Cheng Huang, Heng-Hui Lien, Shih-Hsin Tu, Ching-Shui Huang +4 more
2010Journal of the Formosan Medical Association = Taiwan yi zhi26 citations Open access
Semantic Scholar
Curcumin-induced antitumor effects on triple-negative breast cancer patient-derived xenograft tumor mice through inhibiting salt-induced kinase-3 protein
Tzu-Chun Cheng, John Oliver Sayseng, Shih-Hsin Tu, Ting-Ching Juan +7 more
2021Journal of Food and Drug Analysis25 citations Open access
Semantic Scholar
Identification of genes and pathways related to lymphovascular invasion in breast cancer patients: A bioinformatics analysis of gene expression profiles
S. Klahan, Henry Sung-Ching Wong, Shih-Hsin Tu, Wan-Hsuan Chou +8 more
2017Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine25 citations Open access
Semantic Scholar
Tumor targeting and therapeutic assessments of RNA nanoparticles carrying α9-nAChR aptamer and anti-miR-21 in triple-negative breast cancers
You-Cheng Liao, Tzu-Chun Cheng, Shih-Hsin Tu, Jungshan Chang +3 more
2023Molecular Therapy: Nucleic Acids24 citations Open access
Semantic Scholar
The impact of the effectiveness of GATA3 as a prognostic factor in breast cancer.
A. Fararjeh, Shih-Hsin Tu, Li-Ching Chen, Yun-Ru Liu +6 more
2018Human Pathology23 citations
Semantic Scholar
Alteration of α-tocopherol-associated protein (TAP) expression in human breast epithelial cells during breast cancer development.
Ka-Wai Tam, Chi-Tang Ho, Wen-Jui Lee, Shih-Hsin Tu +5 more
2013Food Chemistry23 citations
Semantic Scholar
The in vivo antitumor effects on human COLO 205 cancer cells of the 4,7-dimethoxy-5-(2-propen-1-yl)-1,3-benzodioxole (apiole) derivative of 5-substituted 4,7-dimethoxy-5-methyl-l,3-benzodioxole (SY-1) isolated from the fruiting body of Antrodia camphorate.
Po-Li Wei, Shih-Hsin Tu, Hsiu-Man Lien, Li-Ching Chen +7 more
2012Journal of Cancer Research and Therapeutics23 citations Open access
Semantic Scholar
Oestrogen receptor-regulated glutathione S-transferase mu 3 expression attenuates hydrogen peroxide-induced cytotoxicity, which confers tamoxifen resistance on breast cancer cells
Juo-Han Lin, Shih-Hsin Tu, Li-Ching Chen, Chi-Cheng Huang +6 more
2018Breast Cancer Research and Treatment22 citations
Semantic Scholar
Tea polyphenol epigallocatechin-3-gallate inhibits cell proliferation in a patient-derived triple-negative breast cancer xenograft mouse model via inhibition of proline-dehydrogenase-induced effects
Wen-Jui Lee, Tzu-Chun Cheng, Yen Yun, Chia-Lang Fang +7 more
2021Journal of Food and Drug Analysis20 citations Open access
Semantic Scholar
Multi-gene signature of microcalcification and risk prediction among Taiwanese breast cancer
Hsin-Tien Tsai, Ching-Shui Huang, Chao-Chiang Tu, Chih-Yi Liu +5 more
2020Scientific Reports20 citations Open access
Semantic Scholar
A New Histone Deacetylase Inhibitor Enhances Radiation Sensitivity through the Induction of Misfolded Protein Aggregation and Autophagy in Triple-Negative Breast Cancer
Hui-Wen Chiu, Ya-Ling Yeh, S. Ho, Yuan-Hua Wu +6 more
2019Cancers19 citations Open access
Semantic Scholar
α-Tocopherol succinate enhances pterostilbene anti-tumor activity in human breast cancer cells in vivo and in vitro
Ka-Wai Tam, Chi-Tang Ho, Shih-Hsin Tu, Wen-Jui Lee +5 more
2017OncoTarget19 citations Open access
Semantic Scholar
Melatonin promotes neuroblastoma cell differentiation by activating hyaluronan synthase 3‐induced mitophagy
Wen-Jui Lee, Li-Ching Chen, Juo-Han Lin, Tzu-Chun Cheng +5 more
2019Cancer Medicine18 citations Open access
Semantic Scholar
Long‐term exposure to extremely low‐dose of nicotine and 4‐(methylnitrosamino)‐1‐(3‐pyridyl)‐1‐butanone (NNK) induce non‐malignant breast epithelial cell transformation through activation of the a9‐nicotinic acetylcholine receptor‐mediated signaling pathway
A. Fararjeh, Shih-Hsin Tu, Li-Ching Chen, Tzu-Chun Cheng +8 more
2018Environmental Toxicology17 citations Open access
Semantic Scholar
A rapid and quantitative method to detect human circulating tumor cells in a preclinical animal model
Shih-Hsin Tu, Y. Hsieh, Li-Chi Huang, Chun-Yu Lin +4 more
2017BMC Cancer17 citations Open access
Semantic Scholar
SP1-regulated p27/Kip1 gene expression is involved in terbinafine-induced human A431 cancer cell differentiation: an in vitro and in vivo study.
Ching-Shui Huang, Wei-Lu Ho, Wen-Sen Lee, M. Sheu +9 more
2008Biochemical Pharmacology16 citations
Semantic Scholar
Electrospun Polylactic Acid (PLLA) Microtube Array Membrane (MTAM)—An Advanced Substrate for Anticancer Drug Screening
Chia-Hsuan Tseng, Wan-Ting Huang, C. Chew, Jun-Kai Lai +5 more
2019Materials15 citations Open access
Semantic Scholar
Protein phosphatase Mg2+/Mn2+ dependent 1F promotes smoking-induced breast cancer by inactivating phosphorylated-p53-induced signals
Shih-Hsin Tu, Yingxuan Lin, Chi-Cheng Huang, Po-Sheng Yang +5 more
2016OncoTarget15 citations Open access
Semantic Scholar
A Novel HLA-A2–restricted CTL Epitope of Tumor-associated Antigen L6 can Inhibit Tumor Growth In Vivo
Shih-Hsin Tu, Hsing-I Huang, Su-I Lin, Hsin-Yu Liu +7 more
2012Journal of immunotherapy15 citations
Semantic Scholar
CHRNA9 polymorphisms and smoking exposure synergize to increase the risk of breast cancer in Taiwan.
Y. Hsieh, Chia-Hwa Lee, Shih-Hsin Tu, Chih-Hsiung Wu +5 more
2014Carcinogenesis14 citations Open access
Semantic Scholar
Prediction consistency and clinical presentations of breast cancer molecular subtypes for Han Chinese population
Chi-Cheng Huang, Shih-Hsin Tu, Heng-Hui Lien, J. Jeng +6 more
2012Journal of Translational Medicine14 citations Open access
Semantic Scholar
Pu-erh Tea Extract Attenuates Nicotine-Induced Foam Cell Formation in Primary Cultured Monocytes: An in Vitro Mechanistic Study.
Shih-Hsin Tu, Ming-Yao Chen, Li-Ching Chen, Y. Mao +11 more
2016Journal of Agricultural and Food Chemistry13 citations
Semantic Scholar
A model-based circular binary segmentation algorithm for the analysis of array CGH data
Fang-Han Hsu, Hung I. Chen, Mong-Hsun Tsai, L. Lai +4 more
2011BMC Research Notes13 citations Open access
Semantic Scholar
Multiclass Prediction with Partial Least Square Regression for Gene Expression Data: Applications in Breast Cancer Intrinsic Taxonomy
Chi-Cheng Huang, Shih-Hsin Tu, Ching-Shui Huang, Heng-Hui Lien +2 more
2013BioMed Research International12 citations Open access
Semantic Scholar
Small G protein signalling modulator 2 (SGSM2) is involved in oestrogen receptor-positive breast cancer metastasis through enhancement of migratory cell adhesion via interaction with E-cadherin
Juo-Han Lin, Wen-Jui Lee, Han-Chung Wu, Chih-Hsiung Wu +8 more
2019Cell Adhesion & Migration11 citations Open access
Semantic Scholar
MSH2 rs2303425 Polymorphism is Associated with Early-Onset Breast Cancer in Taiwan
Y. Hsieh, E. Cho, Shih-Hsin Tu, Chih-Hsiung Wu +7 more
2017Annals of Surgical Oncology11 citations
Semantic Scholar
Differential whole-genome doubling and homologous recombination deficiencies across breast cancer subtypes from the Taiwanese population
Chia-Hsin Wu, Chia-Shan Hsieh, Yo-Cheng Chang, Chi-Cheng Huang +11 more
2021Communications Biology7 citations Open access
Semantic Scholar
Pu-erh tea attenuates smoking-induced foam cell formation through inhibition of the α9-nicotinic-acetylcholine receptor expression in monocytes: An ex vivo study
Li-Ching Chen, Ming-Yao Chen, Shih-Hsin Tu, Min-Hsiung Pan +4 more
20167 citations Open access
Semantic Scholar

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