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S. Mazurek · SciRah

Researcher profile · Semantic Scholar

S. Mazurek

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S. Mazurek — researcher profile on SciRah

h-index: 33
Works: 68
Citations: 5,082

Most-cited papers

Pyruvate kinase type M2 and its role in tumor growth and spreading.
S. Mazurek, C. Boschek, F. Hugo, E. Eigenbrodt
2005Seminars in Cancer Biology832 citations
Semantic Scholar
Pyruvate kinase type M2: a key regulator of the metabolic budget system in tumor cells.
S. Mazurek
2011International Journal of Biochemistry and Cell Biology691 citations
Semantic Scholar
Modulation of type M2 pyruvate kinase activity by the human papillomavirus type 16 E7 oncoprotein.
W. Zwerschke, S. Mazurek, P. Massimi, L. Banks +2 more
1999Proceedings of the National Academy of Sciences of the United States of America282 citations Open access
Semantic Scholar
Metabolic analysis of senescent human fibroblasts reveals a role for AMP in cellular senescence.
W. Zwerschke, S. Mazurek, Petra Stöckl, Eveline Hütter +2 more
2003Biochemical Journal235 citations Open access
Semantic Scholar
Pyruvate kinase M2 and cancer: an updated assessment
M. A. Iqbal, Vibhor Gupta, P. Gopinath, S. Mazurek +1 more
2014FEBS Letters189 citations
Semantic Scholar
The tumor metabolome.
S. Mazurek, E. Eigenbrodt
2003Anticancer Research167 citations
Semantic Scholar
The Role of Phosphometabolites in Cell Proliferation, Energy Metabolism, and Tumor Therapy
S. Mazurek, C. Boschek, Erich Eigenbrodt
1997Journal of Bioenergetics and Biomembranes166 citations
Semantic Scholar
Pyruvate kinase type M2: a crossroad in the tumor metabolome
S. Mazurek, Helmut Grimm, C. Boschek, P. Vaupel +1 more
2002British Journal of Nutrition159 citations Open access
Semantic Scholar
Effects of the human papilloma virus HPV-16 E7 oncoprotein on glycolysis and glutaminolysis: role of pyruvate kinase type M2 and the glycolytic-enzyme complex.
S. Mazurek, W. Zwerschke, P. Jansen-Dürr, E. Eigenbrodt
2001Biochemical Journal147 citations Open access
Semantic Scholar
Therapeutic targeting of glutaminolysis as an essential strategy to combat cancer.
J. Matés, F. D. Di Paola, José A. Campos-Sandoval, S. Mazurek +1 more
2020Seminars in Cell and Developmental Biology138 citations Open access
Semantic Scholar
Posttranslational Modifications of Pyruvate Kinase M2: Tweaks that Benefit Cancer
G. Prakasam, Mohammad Askandar Iqbal, R. Bamezai, S. Mazurek
2018Frontiers in Oncology135 citations Open access
Semantic Scholar
Faecal tumour M2 pyruvate kinase: a new, sensitive screening tool for colorectal cancer
P. Hardt, S. Mazurek, M. Toepler, P. Schlierbach +3 more
2004British Journal of Cancer135 citations Open access
Semantic Scholar
Metabolic cooperation between different oncogenes during cell transformation: interaction between activated ras and HPV-16 E7
S. Mazurek, W. Zwerschke, P. Jansen-Dürr, E. Eigenbrodt
2001Oncogene116 citations Open access
Semantic Scholar
Effect of Extracellular AMP on Cell Proliferation and Metabolism of Breast Cancer Cell Lines with High and Low Glycolytic Rates*
S. Mazurek, A. Michel, E. Eigenbrodt
1997Journal of Biological Chemistry114 citations Open access
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Premature senescence of human endothelial cells induced by inhibition of glutaminase
H. Unterluggauer, S. Mazurek, B. Lener, Eveline Hütter +3 more
2008Biogerontology (Dordrecht)107 citations
Semantic Scholar
Pyruvate kinase isoenzyme M2 is a glycolytic sensor differentially regulating cell proliferation, cell size and apoptotic cell death dependent on glucose supply.
Gilles A. Spoden, Ursula Rostek, S. Lechner, Maria C. Mitterberger +2 more
2009Experimental Cell Research98 citations Open access
Semantic Scholar
Isotype‐specific inhibitors of the glycolytic key regulator pyruvate kinase subtype M2 moderately decelerate tumor cell proliferation
Gilles A. Spoden, S. Mazurek, D. Morandell, Nicole Bacher +4 more
2008International Journal of Cancer86 citations Open access
Semantic Scholar
Pyruvate kinase type M2: a key regulator within the tumour metabolome and a tool for metabolic profiling of tumours.
S. Mazurek
2007Ernst Schering Foundation symposium proceedings85 citations
Semantic Scholar
Quantification of tumor type M2 pyruvate kinase (Tu M2-PK) in human carcinomas.
E. Eigenbrodt, D. Basenau, S. Holthusen, S. Mazurek +1 more
1997Anticancer Research81 citations
Semantic Scholar
Alterations in the glycolytic and glutaminolytic pathways after malignant transformation of rat liver oval cells
S. Mazurek, E. Eigenbrodt, K. Failing, P. Steinberg
1999Journal of Cellular Physiology72 citations
Semantic Scholar
L- and M2- pyruvate kinase expression in renal cell carcinomas and their metastases
U. Brinck, G. Fischer, Erich Eigenbrodt, M. Oehmke +1 more
2004Virchows Archiv69 citations
Semantic Scholar
Pyruvate kinase and the interaction of amino acid and carbohydrate metabolism in solid tumors.
Erich Eigenbrodt, F. Kallinowski, M. Ott, S. Mazurek +1 more
1998Anticancer Research66 citations
Semantic Scholar
Tumor M2-PK and glutaminolytic enzymes in the metabolic shift of tumor cells.
S. Mazurek, Helmut Grimm, M. Oehmke, G. Weiße +2 more
2000Anticancer Research65 citations
Semantic Scholar
Regulation of pyruvate kinase type M2 by A-Raf: a possible glycolytic stop or go mechanism.
S. Mazurek, H. Drexler, J. Troppmair, E. Eigenbrodt +1 more
2007Anticancer Research64 citations
Semantic Scholar
Phosphoglycerate Mutase-derived Polypeptide Inhibits Glycolytic Flux and Induces Cell Growth Arrest in Tumor Cell Lines*
M. Engel, S. Mazurek, E. Eigenbrodt, C. Welter
2004Journal of Biological Chemistry61 citations Open access
Semantic Scholar
Regulation of glycolysis by Raf protein serine/threonine kinases.
Véronique Le Mellay, R. Houben, J. Troppmair, C. Hagemann +7 more
2002Advances in Enzyme Regulation50 citations
Semantic Scholar
Interaction between HERC1 and M2‐type pyruvate kinase
Francesc R. Garcia-Gonzalo, C. Cruz, P. Muñoz, S. Mazurek +4 more
2003FEBS Letters47 citations
Semantic Scholar
In vitro effect of extracellular AMP on MCF‐7 breast cancer cells: Inhibition of glycolysis and cell proliferation
F. Hugo, S. Mazurek, Ute Zander, E. Eigenbrodt
1992Journal of Cellular Physiology46 citations
Semantic Scholar
Studies on associations of glycolytic and glutaminolytic enzymes in MCF‐7 cells: Role of P36
S. Mazurek, F. Hugo, K. Failing, Erich Eigenbrodt
1996Journal of Cellular Physiology42 citations
Semantic Scholar
Osteogenic differentiation capacity of human mesenchymal stromal cells in response to extracellular calcium with special regard to connexin 43.
Alena-Svenja Wagner, K. Glenske, V. Wolf, D. Fietz +5 more
2017Annals of Anatomy41 citations
Semantic Scholar
Pyruvate kinase M2 is a novel diagnostic marker and predicts tumour progression in human biliary tract cancer
D. Dhar, S. W. Olde Damink, J. Brindley, A. Godfrey +7 more
2012Cancer41 citations Open access
Semantic Scholar
Metabolic characteristics of different malignant cancer cell lines.
S. Mazurek, Helmut Grimm, S. Wilker, S. Leib +1 more
1998Anticancer Research40 citations
Semantic Scholar
Robust metabolic adaptation underlying tumor progression
Pedro Vizán, S. Mazurek, M. Cascante
2008Metabolomics37 citations
Semantic Scholar
Mesenchymal stem cells promote pancreatic β-cell regeneration through downregulation of FoxO1 pathway
R. Khatri, S. Mazurek, S. F. Petry, T. Linn
2020Stem cell research & therapeutics33 citations Open access
Semantic Scholar
Phytocompounds Targeting Metabolic Reprogramming in Cancer: An Assessment of Role, Mechanisms, Pathways, and Therapeutic Relevance.
Asifa Khan, S. Siddiqui, S. Husain, S. Mazurek +1 more
2021Journal of Agricultural and Food Chemistry27 citations
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Chapter 10 – Carbohydrate Metabolism and Neoplasia: New Perspectives for Diagnosis and Therapy
E. Eigenbrodt, U. Gerbracht, S. Mazurek, P. Presek +1 more
199426 citations
Semantic Scholar
Double role of pyruvate kinase type M2 in the regulation of phosphometabolite pools
E. Eigenbrodt, S. Mazurek, R. Friis
199825 citations
Semantic Scholar
Metabolic Signatures of Cryptosporidium parvum-Infected HCT-8 Cells and Impact of Selected Metabolic Inhibitors on C. parvum Infection under Physioxia and Hyperoxia
J. Vélez, Z. Velásquez, L. Silva, U. Gärtner +5 more
2021Biology23 citations Open access
Semantic Scholar
Metabolic requirements of Besnoitia besnoiti tachyzoite-triggered NETosis
E. Zhou, I. Conejeros, U. Gärtner, S. Mazurek +2 more
2019Parasitology Research23 citations
Semantic Scholar
Interference with energy metabolism by 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside induces HPV suppression in cervical carcinoma cells and apoptosis in the absence of LKB1.
J. Nafz, Johanna De-Castro Arce, Verena Fleig, Andrea Patzelt +2 more
2007Biochemical Journal22 citations Open access
Semantic Scholar
Biomaterial based treatment of osteoclastic/osteoblastic cell imbalance - Gelatin-modified calcium/strontium phosphates.
B. Kruppke, Alena-Svenja Wagner, M. Rohnke, C. Heinemann +6 more
2019Materials Science and Engineering C: Materials for Biological Applications21 citations
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Pyruvate kinase M2: A key enzyme of the tumor metabolome and its medical relevance.
S. Mazurek
201220 citations
Semantic Scholar
Metabolic signatures of Besnoitia besnoiti-infected endothelial host cells and blockage of key metabolic pathways indicate high glycolytic and glutaminolytic needs of the parasite
A. Taubert, C. Hermosilla, L. Silva, A. Wieck +2 more
2016Parasitology Research19 citations
Semantic Scholar
Energy metabolism in the involuting mammary gland.
S. Mazurek, G. Weiße, G. Wüst, A. Schäfer-Schwebel +2 more
1999In Vivo18 citations
Semantic Scholar
Pyruvate kinase M2: regulatory circuits and potential for therapeutic intervention.
Vibhor Gupta, K. Wellen, S. Mazurek, R. Bamezai
2014Current pharmaceutical design16 citations
Semantic Scholar
In vivo factors influencing tumour M2-pyruvate kinase level in human pancreatic cancer cell lines
Y. Kumar, S. Mazurek, Shi-Yu Yang, K. Failing +3 more
2010Tumor Biology16 citations
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Interplay between epigenetics & cancer metabolism.
Vibhor Gupta, P. Gopinath, M. A. Iqbal, S. Mazurek +2 more
2014Current pharmaceutical design15 citations
Semantic Scholar
First Metabolic Insights into Ex Vivo Cryptosporidium parvum-Infected Bovine Small Intestinal Explants Studied under Physioxic Conditions
J. Vélez, L. Silva, U. Gärtner, A. Daugschies +3 more
2021Biology10 citations Open access
Semantic Scholar
Plasma levels of HER-2/neu, tumor type M2 pyruvate kinase and its tyrosine-phosphorylated metabolite in advanced breast cancer.
D. Lüftner, S. Mazurek, P. Henschke, J. Mesterharm +4 more
2003Anticancer Research9 citations
Semantic Scholar
Effect of long term palmitate treatment on osteogenic differentiation of human mesenchymal stromal cells - Impact of albumin
K. Glenske, Kaija Schäpe, A. Wieck, K. Failing +4 more
2020Bone Reports8 citations Open access
Semantic Scholar

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E. Eigenbrodt — researcher profile on SciRah
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W. Zwerschke×7
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