C. Bellera

Most-cited papers

Challenges and opportunities with drug repurposing: finding strategies to find alternative uses of therapeutics
A. Talevi, C. Bellera
2019Expert Opinion on Drug Discovery221 citations Open access
Semantic Scholar
Computer-guided drug repurposing: identification of trypanocidal activity of clofazimine, benidipine and saquinavir.
C. Bellera, D. Balcazar, M. C. Vanrell, A. Florencia Casassa +8 more
2015European journal of medicinal chemistry56 citations Open access
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Application of descriptors based on Lipinski's rules in the QSPR study of aqueous solubilities.
P. Duchowicz, A. Talevi, C. Bellera, L. Bruno-Blanch +1 more
2007Bioorganic & Medicinal Chemistry51 citations
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Optimal biological dose: a systematic review in cancer phase I clinical trials
J. Fraisse, D. Dinart, D. Tosi, C. Bellera +1 more
2021BMC Cancer46 citations Open access
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Strengths and Weaknesses of Docking Simulations in the SARS-CoV-2 Era: the Main Protease (Mpro) Case Study
M. Llanos, M. Gantner, Santiago Rodríguez, Lucas N. Alberca +3 more
2021Journal of Chemical Information and Modeling44 citations Open access
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Prediction of drug intestinal absorption by new linear and non-linear QSPR.
A. Talevi, M. Goodarzi, E. V. Ortiz, P. Duchowicz +4 more
2011European journal of medicinal chemistry44 citations
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An integrated drug development approach applying topological descriptors.
A. Talevi, C. Bellera, M. D. Di Ianni, P. Duchowicz +2 more
2012Current Computer - Aided Drug Design40 citations
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Application of Computer-Aided Drug Repurposing in the Search of New Cruzipain Inhibitors: Discovery of Amiodarone and Bromocriptine Inhibitory Effects
C. Bellera, D. Balcazar, Lucas N. Alberca, C. Labriola +2 more
2013Journal of Chemical Information and Modeling37 citations Open access
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Synthesis of 2‐Hydrazolyl‐4‐Thiazolidinones Based on Multicomponent Reactions and Biological Evaluation Against Trypanosoma Cruzi
Chiara Pizzo, C. Saiz, A. Talevi, Luciana Gavernet +8 more
2011Chemical Biology and Drug Design36 citations
Semantic Scholar
A successful virtual screening application: prediction of anticonvulsant activity in MES test of widely used pharmaceutical and food preservatives methylparaben and propylparaben
A. Talevi, C. Bellera, E. Castro, L. Bruno-Blanch
2007J. Comput. Aided Mol. Des.35 citations
Semantic Scholar
Neglected Tropical Protozoan Diseases: Drug Repositioning as a Rational Option.
M. L. Sbaraglini, M. C. Vanrell, C. Bellera, G. Benaim +3 more
2016Current Topics in Medicinal Chemistry33 citations Open access
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CNS drug development - lost in translation?
A. Talevi, C. Bellera, M. D. Di Ianni, M. Gantner +2 more
2012Mini-Reviews in Medical Chemistry31 citations Open access
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Novel cruzipain inhibitors for the chemotherapy of chronic Chagas disease.
M. L. Sbaraglini, C. Bellera, L. Fraccaroli, L. Larocca +3 more
2016International Journal of Antimicrobial Agents27 citations Open access
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Can drug repurposing strategies be the solution to the COVID-19 crisis?
C. Bellera, M. Llanos, M. Gantner, Santiago Rodríguez +3 more
2020Expert Opinion on Drug Discovery22 citations Open access
Semantic Scholar
Identification of Levothyroxine Antichagasic Activity through Computer-Aided Drug Repurposing
C. Bellera, D. Balcazar, Lucas N. Alberca, C. Labriola +2 more
2014TheScientificWorldJournal22 citations Open access
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LIDeB Tools: a Latin American resource of freely available, open-source cheminformatics apps
Denis N. Prada Gori, Lucas N. Alberca, Santiago Rodríguez, Juan I. Alice +3 more
2022Artificial Intelligence in the Life Sciences21 citations Open access
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iRaPCA and SOMoC: Development and Validation of Web Applications for New Approaches for the Clustering of Small Molecules
Denis N. Prada Gori, M. Llanos, C. Bellera, A. Talevi +1 more
2022Journal of Chemical Information and Modeling21 citations Open access
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High-throughput drug repositioning for the discovery of new treatments for Chagas disease.
C. Bellera, M. L. Sbaraglini, D. Balcazar, L. Fraccaroli +6 more
2015Mini-Reviews in Medical Chemistry21 citations Open access
Semantic Scholar
In Silico Drug Repositioning for Chagas Disease.
C. Bellera, Lucas N. Alberca, M. L. Sbaraglini, A. Talevi
2020Current Medicinal Chemistry15 citations
Semantic Scholar
LIDEB's Useful Decoys (LUDe): A freely available decoy-generation tool. Benchmarking and scope
Lucas N. Alberca, Denis N. Prada Gori, M. Fallico, A. Fassio +2 more
2025Artificial Intelligence in the Life Sciences13 citations Open access
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One-Compartment Pharmacokinetic Model
A. Talevi, C. Bellera
2021The ADME Encyclopedia13 citations
Semantic Scholar
Quantitative structure–activity relationship models for compounds with anticonvulsant activity
C. Bellera, A. Talevi
2019Expert Opinion on Drug Discovery11 citations
Semantic Scholar
Knowledge-Based Drug Repurposing: A Rational Approach Towards the Identification of Novel Medical Applications of Known Drugs
C. Bellera, M. D. Di Ianni, M. L. Sbaraglini, E. Castro +2 more
20159 citations
Semantic Scholar
Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro
Santiago Ruatta, Denis N. Prada Gori, Martín Fló Díaz, Franca Lorenzelli +55 more
2023Frontiers in Pharmacology8 citations Open access
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pKa Determination
A. Talevi, C. Bellera
2021The ADME Encyclopedia7 citations
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Combined therapy with Benznidazole and repurposed drugs Clofazimine and Benidipine for chronic Chagas disease.
M. L. Sbaraglini, C. Bellera, Juan Quarroz Braghini, Yésica Areco +7 more
2019European journal of medicinal chemistry7 citations Open access
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Drug repurposing screening validated by experimental assays identifies two clinical drugs targeting SARS-CoV-2 main protease
Denis N. Prada Gori, Santiago Ruatta, Martín Fló, Lucas N. Alberca +9 more
2023Frontiers in Drug Discovery6 citations Open access
Semantic Scholar
Tackling the issue of confined chemical space with AI-based de novo drug design and molecular optimization
A. Talevi, Lucas N. Alberca, C. Bellera
2025Expert Opinion on Drug Discovery5 citations Open access
Semantic Scholar
Ensemble learning application to discover new trypanothione synthetase inhibitors
Juan I. Alice, C. Bellera, D. Benítez, M. Comini +2 more
2021Molecular diversity5 citations Open access
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Modern Approaches for the Discovery of Anti-Infectious Drugs for the Treatment of Neglected Diseases.
C. Bellera, M. L. Sbaraglini, A. Talevi
2018Current Topics in Medicinal Chemistry5 citations Open access
Semantic Scholar
Clustering of small molecules: new perspectives and their impact on natural product lead discovery
A. Talevi, C. Bellera
2024Frontiers in Natural Products4 citations Open access
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pH Partition Theory
A. Talevi, C. Bellera
2021The ADME Encyclopedia4 citations
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Enterohepatic Recycling
A. Talevi, C. Bellera
2021The ADME Encyclopedia4 citations
Semantic Scholar
An update on the novel methods for the discovery of antiseizure and antiepileptogenic medications: where are we in 2024?
A. Talevi, C. Bellera
2024Expert Opinion on Drug Discovery3 citations
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Free Drug Theory
A. Talevi, C. Bellera
2021The ADME Encyclopedia3 citations
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Phase 0 and Phase III Transport
A. Talevi, C. Bellera
2021The ADME Encyclopedia3 citations
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Isolation and characterization of Bioactive Metabolite from Bacillus safensis VRKK2 for controlling Bacterial blight disease in Cowpea.
J. F. Morales, S. Chuguransky, Lucas N. Alberca, Juan I. Alice +4 more
2020Cardiovascular & Hematological Agents in Medicinal Chemistry3 citations Open access
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Drug Metabolism Functionalization (Phase I) Reactions
A. Talevi, C. Bellera
2021The ADME Encyclopedia2 citations Open access
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Homology Modeling and Molecular Dynamics Simulations of Trypanosoma cruzi Phosphodiesterase b1
Manuel A. Llanos, Lucas N. Alberca, S. V. Vílchez Larrea, Alejandra C. Schoijet +4 more
2021Chemistry and Biodiversity2 citations
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Unbound Brain-to-Plasma Partition Coefficient Determination
A. Talevi, C. Bellera
2021The ADME Encyclopedia2 citations
Semantic Scholar
The application of molecular topology for ulcerative colitis drug discovery
C. Bellera, M. D. Di Ianni, A. Talevi
2018Expert Opinion on Drug Discovery2 citations Open access
Semantic Scholar
Computer-Aided Discovery of Drugs Against Chagas Disease.
C. Bellera, Lucas N. Alberca, A. Talevi
2026Methods in molecular biology1 citations
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Brain-to-Plasma Concentration Ratio and Unbound Partition Coefficient
A. Talevi, C. Bellera
2021The ADME Encyclopedia1 citations
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Organic Anion Transporters and Organic Anion Transporting Polypeptides
A. Talevi, C. Bellera
2021The ADME Encyclopedia1 citations
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Personalized Medicine and Drug Metabolism
A. Talevi, C. Bellera
2021The ADME Encyclopedia1 citations Open access
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Active and Facilitated Transport in Drug Absorption
A. Talevi, C. Bellera
2021The ADME Encyclopedia1 citations
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Drug Excretion
A. Talevi, C. Bellera
2021The ADME Encyclopedia1 citations
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Enzyme Induction and Drug Metabolism
A. Talevi, C. Bellera
2021The ADME Encyclopedia1 citations
Semantic Scholar
Recent Advances on Nanotechnology Applications to Cancer Drug Therapy
C. Bellera, M. Gantner, M. E. Ruiz, A. Talevi
20131 citations Open access
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Real and Apparent Volumes of Distribution
A. Talevi, C. Bellera
2021The ADME Encyclopedia0 citations
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