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L. Castagnoli · SciRah

Researcher profile · Semantic Scholar

L. Castagnoli

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L. Castagnoli — researcher profile on SciRah

h-index: 47
Works: 143
Citations: 11K

Most-cited papers

MINT: the Molecular INTeraction database
A. Chatr-aryamontri, A. Céol, L. Palazzi, G. Nardelli +3 more
2006Nucleic Acids Res.1,463 citations Open access
Semantic Scholar
MINT, the molecular interaction database: 2012 update
L. Licata, Leonardo Briganti, Daniele Peluso, L. Perfetto +8 more
2011Nucleic Acids Res.1,048 citations Open access
Semantic Scholar
MINT, the molecular interaction database: 2009 update
A. Céol, A. Chatr-aryamontri, L. Licata, Daniele Peluso +4 more
2009Nucleic Acids Res.552 citations Open access
Semantic Scholar
mentha: a resource for browsing integrated protein-interaction networks
Alberto C, L. Castagnoli, G. Cesareni
2013Nature Methods327 citations
Semantic Scholar
Microfluidic-enhanced 3D bioprinting of aligned myoblast-laden hydrogels leads to functionally organized myofibers in vitro and in vivo.
M. Costantini, Stefano Testa, P. Mozetic, A. Barbetta +14 more
2017Biomaterials270 citations Open access
Semantic Scholar
SIGNOR: a database of causal relationships between biological entities
L. Perfetto, Leonardo Briganti, Alberto Calderone, A. C. Perpetuini +15 more
2015Nucleic Acids Res.231 citations Open access
Semantic Scholar
The human phosphatase interactome: An intricate family portrait
F. Sacco, L. Perfetto, L. Castagnoli, G. Cesareni
2012FEBS Letters228 citations Open access
Semantic Scholar
SIGNOR 2.0, the SIGnaling Network Open Resource 2.0: 2019 update
L. Licata, Prisca Lo Surdo, M. Iannuccelli, Alessandro Palma +6 more
2019Nucleic Acids Res.214 citations Open access
Semantic Scholar
Bayesian Modeling of the Yeast SH3 Domain Interactome Predicts Spatiotemporal Dynamics of Endocytosis Proteins
Raffi Tonikian, Xiaofeng Xin, Christopher P. Toret, D. Gfeller +17 more
2009PLoS Biology212 citations Open access
Semantic Scholar
VirusMINT: a viral protein interaction database
A. Chatr-aryamontri, A. Céol, Daniele Peluso, A. P. Nardozza +8 more
2008Nucleic Acids Res.206 citations Open access
Semantic Scholar
Benchmarking of the 2010 BioCreative Challenge III text-mining competition by the BioGRID and MINT interaction databases
Martin Krallinger, M. Vazquez, F. Leitner, David Salgado +30 more
2011152 citations
Semantic Scholar
SIGNOR 3.0, the SIGnaling network open resource 3.0: 2022 update
Prisca Lo Surdo, M. Iannuccelli, Silvia Contino, L. Castagnoli +3 more
2022Nucleic Acids Res.143 citations Open access
Semantic Scholar
Adipogenesis of skeletal muscle fibro/adipogenic progenitors is affected by the WNT5a/GSK3/β-catenin axis
A. Reggio, M. Rosina, Alessandro Palma, A. Cerquone Perpetuini +10 more
2020Cell Death and Differentiation137 citations Open access
Semantic Scholar
The SH2 domain interaction landscape
M. Tinti, L. Kiemer, S. Costa, M. L. Miller +15 more
2013Cell Reports129 citations Open access
Semantic Scholar
Diverse driving forces underlie the invariant occurrence of the T42A, E139D, I282V and T468M SHP2 amino acid substitutions causing Noonan and LEOPARD syndromes.
S. Martinelli, P. Torreri, M. Tinti, L. Stella +10 more
2008Human Molecular Genetics93 citations Open access
Semantic Scholar
DOMINO: a database of domain–peptide interactions
A. Céol, A. Chatr-aryamontri, Elena Santonico, R. Sacco +2 more
2006Nucleic Acids Res.93 citations Open access
Semantic Scholar
Deep Proteomics of Breast Cancer Cells Reveals that Metformin Rewires Signaling Networks Away from a Pro-growth State.
F. Sacco, A. Silvestri, D. Posca, S. Pirrò +4 more
2016Cell Systems85 citations Open access
Semantic Scholar
Tumor Suppressor Density-enhanced Phosphatase-1 (DEP-1) Inhibits the RAS Pathway by Direct Dephosphorylation of ERK1/2 Kinases*
F. Sacco, M. Tinti, Anita Palma, E. Ferrari +5 more
2009Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Selectivity and promiscuity in the interaction network mediated by protein recognition modules
L. Castagnoli, A. Costantini, C. Dall'Armi, S. Gonfloni +5 more
2004FEBS Letters75 citations
Semantic Scholar
Fibro-adipogenic progenitors of dystrophic mice are insensitive to NOTCH regulation of adipogenesis
Milica Marinkovic, C. Fuoco, F. Sacco, A. Cerquone Perpetuini +13 more
2019Life Science Alliance73 citations Open access
Semantic Scholar
The Protein-Protein Interaction tasks of BioCreative III: classification/ranking of articles and linking bio-ontology concepts to full text
Martin Krallinger, Miguel Vazquez, F. Leitner, David Salgado +30 more
2011BMC Bioinformatics63 citations Open access
Semantic Scholar
Metabolic reprogramming of fibro/adipogenic progenitors facilitates muscle regeneration
A. Reggio, M. Rosina, Natalie Krahmer, Alessandro Palma +11 more
2020Life Science Alliance62 citations Open access
Semantic Scholar
HuPho: the human phosphatase portal
S. Liberti, Alberto C, F. Sacco, L. Perfetto +7 more
2012The FEBS Journal57 citations Open access
Semantic Scholar
Metformin Induces Apoptosis and Downregulates Pyruvate Kinase M2 in Breast Cancer Cells Only When Grown in Nutrient-Poor Conditions
A. Silvestri, F. Palumbo, I. Rasi, D. Posca +4 more
2015PLoS ONE56 citations Open access
Semantic Scholar
Metformin Protects Skeletal Muscle from Cardiotoxin Induced Degeneration
F. Langone, S. Cannata, C. Fuoco, Daniele Lettieri-Barbato +6 more
2014PLoS ONE56 citations Open access
Semantic Scholar
The 4G10, pY20 and p-TYR-100 antibody specificity: profiling by peptide microarrays.
M. Tinti, A. P. Nardozza, E. Ferrari, F. Sacco +3 more
2012New Biotechnology56 citations Open access
Semantic Scholar
The protein interaction network mediated by human SH3 domains.
M. Carducci, L. Perfetto, Leonardo Briganti, S. Paoluzi +5 more
2012Biotechnology Advances55 citations
Semantic Scholar
Identification of New Substrates of the Protein-tyrosine Phosphatase PTP1B by Bayesian Integration of Proteome Evidence
E. Ferrari, M. Tinti, S. Costa, Salvatore Corallino +5 more
2010Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Biofabricating murine and human myo‐substitutes for rapid volumetric muscle loss restoration
M. Costantini, Stefano Testa, E. Fornetti, C. Fuoco +17 more
2020bioRxiv45 citations Open access
Semantic Scholar
Combining peptide recognition specificity and context information for the prediction of the 14‐3‐3‐mediated interactome in S. cerevisiae and H. sapiens
S. Panni, L. Montecchi-Palazzi, L. Kiemer, A. Cabibbo +7 more
2011Proteomics44 citations
Semantic Scholar
CancerGeneNet: linking driver genes to cancer hallmarks
M. Iannuccelli, E. Micarelli, P. L. Surdo, Alessandro Palma +5 more
2019Nucleic Acids Res.41 citations Open access
Semantic Scholar
Metformin Delays Satellite Cell Activation and Maintains Quiescence
T. Pavlidou, Milica Marinkovic, M. Rosina, C. Fuoco +4 more
2019Stem Cells International40 citations Open access
Semantic Scholar
Role of 14-3-3 proteins in the regulation of neutral trehalase in the yeast Saccharomyces cerevisiae.
S. Panni, Christiane Landgraf, R. Volkmer‐Engert, G. Cesareni +1 more
2008FEMS Yeast Research39 citations Open access
Semantic Scholar
DISNOR: a disease network open resource
Prisca Lo Surdo, Alberto C, M. Iannuccelli, L. Licata +4 more
2017Nucleic Acids Res.37 citations Open access
Semantic Scholar
MINT and IntAct contribute to the Second BioCreative challenge: serving the text-mining community with high quality molecular interaction data
A. Chatr-aryamontri, S. Kerrien, J. Khadake, S. Orchard +12 more
2008Genome Biology37 citations Open access
Semantic Scholar
SCA-1 micro-heterogeneity in the fate decision of dystrophic fibro/adipogenic progenitors
G. Giuliani, S. Vumbaca, C. Fuoco, C. Gargioli +9 more
2020bioRxiv35 citations Open access
Semantic Scholar
The immunosuppressant drug azathioprine restrains adipogenesis of muscle Fibro/Adipogenic Progenitors from dystrophic mice by affecting AKT signaling
A. Reggio, Filomena Spada, M. Rosina, Giorgia Massacci +5 more
2019Scientific Reports35 citations Open access
Semantic Scholar
Methods to reveal domain networks.
Elena Santonico, L. Castagnoli, G. Cesareni
2005Drug Discovery Today33 citations
Semantic Scholar
Multiple modification and protein interaction signals drive the Ring finger protein 11 (RNF11) E3 ligase to the endosomal compartment
Elena Santonico, F. Belleudi, Simona Panni, M. Torrisi +2 more
2010Oncogene32 citations Open access
Semantic Scholar
Counteracting Effects Operating on Src Homology 2 Domain-containing Protein-tyrosine Phosphatase 2 (SHP2) Function Drive Selection of the Recurrent Y62D and Y63C Substitutions in Noonan Syndrome
S. Martinelli, A. P. Nardozza, Silvia Delle Vigne, G. Sabetta +10 more
2012Journal of Biological Chemistry31 citations Open access
Semantic Scholar
Regulation of myoblast differentiation by metabolic perturbations induced by metformin
T. Pavlidou, M. Rosina, C. Fuoco, G. Gerini +3 more
2017PLoS ONE29 citations Open access
Semantic Scholar
The cell-autonomous mechanisms underlying the activity of metformin as an anticancer drug
F. Sacco, Alberto C, L. Castagnoli, G. Cesareni
2016British Journal of Cancer28 citations Open access
Semantic Scholar
Characterization of the Skeletal Muscle Secretome Reveals a Role for Extracellular Vesicles and IL1α/IL1β in Restricting Fibro/Adipogenic Progenitor Adipogenesis
S. Vumbaca, G. Giuliani, Valeria Fiorentini, F. Tortolici +7 more
2021Biomolecules26 citations Open access
Semantic Scholar
Mapping the human phosphatome on growth pathways
F. Sacco, P. Gherardini, S. Paoluzi, J. Sáez-Rodríguez +4 more
2012Molecular Systems Biology25 citations Open access
Semantic Scholar
High-Dimensional Single-Cell Quantitative Profiling of Skeletal Muscle Cell Population Dynamics during Regeneration
L. L. Petrilli, Filomena Spada, Alessandro Palma, A. Reggio +5 more
2020Cells24 citations Open access
Semantic Scholar
Binding to DPF-motif by the POB1 EH domain is responsible for POB1-Eps15 interaction
Elena Santonico, S. Panni, M. Falconi, L. Castagnoli +1 more
2007BMC Biochemistry24 citations Open access
Semantic Scholar
Selectivity of the CUBAN domain in the recognition of ubiquitin and NEDD8
L. Castagnoli, Walter Mandaliti, Ridvan Nepravishta, E. Valentini +7 more
2019The FEBS Journal23 citations Open access
Semantic Scholar
Group I Paks support muscle regeneration and counteract cancer‐associated muscle atrophy
A. Cerquone Perpetuini, A. D. Re Cecconi, M. Chiappa, G. B. Martinelli +6 more
2018Journal of Cachexia, Sarcopenia and Muscle23 citations Open access
Semantic Scholar
Janus effect of glucocorticoids on differentiation of muscle fibro/adipogenic progenitors
A. Cerquone Perpetuini, G. Giuliani, A. Reggio, M. Cerretani +8 more
2019Scientific Reports21 citations Open access
Semantic Scholar
RNF11 is a GGA protein cargo and acts as a molecular adaptor for GGA3 ubiquitination mediated by Itch
Elena Santonico, Anna Mattioni, Simona Panni, F. Belleudi +4 more
2014Oncogene20 citations Open access
Semantic Scholar

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G. Cesareni×46
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F. Sacco×13
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C. Fuoco×13
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C. Gargioli×13
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Elena Santonico×11

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M. Iannuccelli×10

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