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S. Hainzl · SciRah

Researcher profile · Semantic Scholar

S. Hainzl

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S. Hainzl — researcher profile on SciRah

h-index: 24
Works: 62
Citations: 1,632

Most-cited papers

IL-37: a new anti-inflammatory cytokine of the IL-1 family.
D. Boraschi, D. Lucchesi, S. Hainzl, M. Leitner +11 more
2011European Cytokine Network370 citations
Semantic Scholar
COL7A1 Editing via CRISPR/Cas9 in Recessive Dystrophic Epidermolysis Bullosa
S. Hainzl, Patricia Peking, T. Kocher, E. Murauer +8 more
2017Molecular Therapy99 citations Open access
Semantic Scholar
Cut and Paste: Efficient Homology-Directed Repair of a Dominant Negative KRT14 Mutation via CRISPR/Cas9 Nickases
T. Kocher, Patricia Peking, A. Klausegger, E. Murauer +8 more
2017Molecular Therapy86 citations Open access
Semantic Scholar
Assessing Protein Immunogenicity with a Dendritic Cell Line-Derived Endolysosomal Degradome
Matthias Egger, A. Jürets, M. Wallner, P. Briza +7 more
2011PLoS ONE76 citations Open access
Semantic Scholar
Dendritic cells activated by interferon-γ/STAT1 express interleukin-31 receptor and release pro-inflammatory mediators upon interleukin-31 treatment
J. Horejs-Hoeck, H. Schwarz, S. Lamprecht, E. Maier +6 more
2012Journal of Immunology67 citations Open access
Semantic Scholar
K14 mRNA reprogramming for dominant epidermolysis bullosa simplex.
V. Wally, M. Brunner, T. Lettner, M. Wagner +6 more
2010Human Molecular Genetics66 citations
Semantic Scholar
On- and off-target effects of paired CRISPR-Cas nickase in primary human cells
Julia Klermund, M. Rhiel, T. Kocher, K. O. Chmielewski +8 more
2024Molecular Therapy52 citations Open access
Semantic Scholar
The pathogenetic role of IL-1β in severe epidermolysis bullosa simplex.
V. Wally, T. Lettner, Patricia Peking, Doris Peckl‐Schmid +4 more
2013Journal of Investigative Dermatology51 citations Open access
Semantic Scholar
QR-313, an antisense oligonucleotide, shows therapeutic efficacy for treatment of dominant and recessive dystrophic epidermolysis bullosa: a preclinical study.
O. Bornert, M. Hogervorst, P. Nauroy, J. Bischof +15 more
2020Journal of Investigative Dermatology49 citations Open access
Semantic Scholar
Improved Double-Nicking Strategies for COL7A1-Editing by Homologous Recombination
T. Kocher, Roland N. Wagner, A. Klausegger, C. Guttmann-Gruber +4 more
2019Molecular Therapy: Nucleic Acids45 citations Open access
Semantic Scholar
A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair.
Patricia Peking, U. Koller, S. Hainzl, S. Kitzmueller +7 more
2016Molecular Therapy: Nucleic Acids44 citations Open access
Semantic Scholar
Lesion-induced accumulation of platelets promotes survival of adult neural stem / progenitor cells.
Ilias Kazanis, M. Feichtner, Simona Lange, Peter Rotheneichner +10 more
2015Experimental Neurology42 citations Open access
Semantic Scholar
Construction and validation of an RNA trans-splicing molecule suitable to repair a large number of COL7A1 mutations
B. Tockner, T. Kocher, S. Hainzl, J. Reichelt +3 more
2016Gene Therapy39 citations Open access
Semantic Scholar
Targeting proliferation of chronic lymphocytic leukemia (CLL) cells through KCa3.1 blockade
E. Grössinger, L. Weiss, S. Zierler, Stefan Rebhandl +11 more
2014Leukemia39 citations Open access
Semantic Scholar
Gene editing-mediated disruption of epidermolytic ichthyosis-associated KRT10 alleles restores filament stability in keratinocytes.
O. March, T. Lettner, A. Klausegger, M. Ablinger +10 more
2019Journal of Investigative Dermatology38 citations Open access
Semantic Scholar
An ex vivo RNA trans‐splicing strategy to correct human generalized severe epidermolysis bullosa simplex
Patricia Peking, J. Breitenbach, M. Ablinger, W. Muss +9 more
2018British Journal of Dermatology34 citations Open access
Semantic Scholar
A Reporter-Based Screen to Identify Potent 3’ Trans-Splicing Molecules for Endogenous RNA Repair
E. Murauer, U. Koller, S. Hainzl, V. Wally +1 more
2013Human Gene Therapy Methods33 citations
Semantic Scholar
Predictable CRISPR/Cas9-Mediated COL7A1 Reframing for Dystrophic Epidermolysis Bullosa.
T. Kocher, O. March, J. Bischof, B. Liemberger +6 more
2020Journal of Investigative Dermatology32 citations Open access
Semantic Scholar
A novel screening system improves genetic correction by internal exon replacement
U. Koller, V. Wally, L. G. Mitchell, A. Klausegger +6 more
2011Nucleic Acids Research32 citations Open access
Semantic Scholar
MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex
T. Lettner, R. Lang, A. Klausegger, S. Hainzl +2 more
2013PLoS ONE29 citations Open access
Semantic Scholar
AID induces intraclonal diversity and genomic damage in CD86+ chronic lymphocytic leukemia cells
Michael Huemer, Stefan Rebhandl, N. Zaborsky, F. Gassner +5 more
2014European Journal of Immunology28 citations Open access
Semantic Scholar
The design and optimization of RNA trans‐splicing molecules for skin cancer therapy
C. Gruber, U. Koller, Eva M. Murauer, S. Hainzl +5 more
2013Molecular Oncology27 citations Open access
Semantic Scholar
A non-viral and selection-free COL7A1 HDR approach with improved safety profile for dystrophic epidermolysis bullosa
T. Kocher, J. Bischof, S. Haas, O. March +11 more
2021Molecular Therapy: Nucleic Acids26 citations Open access
Semantic Scholar
A cancer stem cell-like phenotype is associated with miR-10b expression in aggressive squamous cell carcinomas
M. Wimmer, R. Zauner, M. Ablinger, J. Piñón-Hofbauer +15 more
2020Cell Communication and Signaling25 citations Open access
Semantic Scholar
RNA Trans-Splicing Modulation via Antisense Molecule Interference
B. Liemberger, Josefina Piñón Hofbauer, V. Wally, C. Arzt +6 more
2018International Journal of Molecular Sciences21 citations Open access
Semantic Scholar
Personalized Development of Antisense Oligonucleotides for Exon Skipping Restores Type XVII Collagen Expression in Junctional Epidermolysis Bullosa
M. Ablinger, T. Lettner, N. Friedl, H. Potocki +15 more
2021International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
Trans-Splicing Improvement by the Combined Application of Antisense Strategies
U. Koller, S. Hainzl, T. Kocher, Clemens Hüttner +6 more
2015International Journal of Molecular Sciences20 citations Open access
Semantic Scholar
COL17A1 editing via homology-directed repair in junctional epidermolysis bullosa
I. Petkovic, J. Bischof, T. Kocher, O. March +11 more
2022Frontiers in Medicine19 citations Open access
Semantic Scholar
Generation of rabbit polyclonal human and murine collagen VII monospecific antibodies: A useful tool for dystrophic epidermolysis bullosa therapy studies
O. Bornert, T. Kocher, C. Gretzmeier, B. Liemberger +3 more
2019Matrix Biology Plus19 citations Open access
Semantic Scholar
Paired nicking-mediated COL17A1 reframing for junctional epidermolysis bullosa
J. Bischof, O. March, B. Liemberger, S. Haas +20 more
2022Molecular Therapy17 citations Open access
Semantic Scholar
5′RNA Trans-Splicing Repair of COL7A1 Mutant Transcripts in Epidermolysis Bullosa
E. Mayr, M. Ablinger, T. Lettner, E. Murauer +8 more
2022International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
A defect in the inner kinetochore protein CENPT causes a new syndrome of severe growth failure
C. Hung, B. Volkmar, J. Baker, J. Bauer +9 more
2017PLoS ONE12 citations Open access
Semantic Scholar
Designing Efficient Double RNA trans-Splicing Molecules for Targeted RNA Repair
Clemens Hüttner, E. Murauer, S. Hainzl, T. Kocher +4 more
2016International Journal of Molecular Sciences11 citations Open access
Semantic Scholar
COL7A1 Editing via RNA Trans-Splicing in RDEB-Derived Skin Equivalents
B. Liemberger, J. Bischof, M. Ablinger, S. Hainzl +11 more
2023International Journal of Molecular Sciences9 citations Open access
Semantic Scholar
Splicing Modulation via Antisense Oligonucleotides in Recessive Dystrophic Epidermolysis Bullosa
S. Hainzl, L. Trattner, B. Liemberger, Johannes Bischof +10 more
2024International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Evaluating a Targeted Cancer Therapy Approach Mediated by RNA trans-Splicing In Vitro and in a Xenograft Model for Epidermolysis Bullosa-Associated Skin Cancer
K. Woess, Yuchen Sun, Hanae Morio, Anna Stierschneider +16 more
2022International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Selective Activation of CNS and Reference PPARGC1A Promoters Is Associated with Distinct Gene Programs Relevant for Neurodegenerative Diseases
M. Kwik, S. Hainzl, J. Oppelt, B. Tichy +10 more
2021International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
miR-200b-mediated reversion of a spectrum of epithelial to mesenchymal transition states in recessive dystrophic epidermolysis bullosa squamous cell carcinomas.
J. Illmer, R. Zauner, Josefina Piñón Hofbauer, M. Wimmer +16 more
2023British Journal of Dermatology6 citations Open access
Semantic Scholar
HMCN1 variants aggravate epidermolysis bullosa simplex phenotype
S. Bergson, O. Sarig, M. Giladi, J. Mohamad +23 more
2025Journal of Experimental Medicine5 citations Open access
Semantic Scholar
Prime editing as a promising therapeutic strategy for junctional epidermolysis bullosa.
Markus Hierl, Johannes Bischof, B. Liemberger, T. Kocher +21 more
2025Molecular Therapy4 citations Open access
Semantic Scholar
Treating severe junctional epidermolysis bullosa with artesunate
Sophie Marie Sinz, U. Koller, B. Liemberger, S. Hainzl +9 more
2025SKINdeep3 citations Open access
Semantic Scholar
A Novel Fluorescence-Based Screen of Gene Editing Molecules for Junctional Epidermolysis Bullosa
Janine Zwicklhuber, T. Kocher, B. Liemberger, S. Hainzl +9 more
2023International Journal of Molecular Sciences1 citations Open access
Semantic Scholar
A block staining method using ethanolic phosphotungstic acid for the visualisation of collagens in transmission electron microscopy
A. Obermayer, S. Hainzl, U. Koller, David Lang +2 more
2026PLoS ONE0 citations Open access
Semantic Scholar
LB1171 A novel non-viral therapeutic modality for epidermolysis bullosa: Mitochondria-mediated COL7A1 delivery restored collagen expression in patient derived xenograft model
D. Septiadi, G. Fontana, L. Schmid, S. Gruner +6 more
2026Journal of Investigative Dermatology0 citations
Semantic Scholar
Transmission electron microscopy of dermal collagen using ethanolic phosphotungstic acid staining
A. Obermayer, S. Hainzl, U. Koller, W. Stoiber
2024BIO Web of Conferences0 citations Open access
Semantic Scholar
803 Editing a missense to a nonsense keratin 9 gene mutation restores intermediate filament integrity
T. Trafoier, D. Ortner-Tobider, S. Hainzl, T. Kocher +9 more
2023Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
853 HMCN1 variants aggravate epidermolysis bullosa phenotype
S. Bergson, O. Sarig, A. Nitzan, S. Hainzl +16 more
2023Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
288 Traceless, homology-directed repair-mediated gene editing for junctional epidermolysis bullosa
I. Petkovic, J. Bischof, T. Kocher, O. March +6 more
2022Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
159 CRISPR/Cas9 nickase mediated gene therapy in primary keratinocytes derived from patients with EPPK
T. Trafoier, S. Hainzl, T. Kocher, U. Koller +3 more
2021Journal of Investigative Dermatology0 citations Open access
Semantic Scholar
MiRNA-10b marks aggressive squamous cell carcinomas, and confers a cancer stem cell-like phenotype
M. Wimmer, R. Zauner, M. Ablinger, J. Piñón-Hofbauer +15 more
2020bioRxiv0 citations Open access
Semantic Scholar

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