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M. Cole · SciRah

Researcher profile · Semantic Scholar

M. Cole

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M. Cole — researcher profile on SciRah

h-index: 53
Works: 156
Citations: 11K

Most-cited papers

Nmyc upregulation by sonic hedgehog signaling promotes proliferation in developing cerebellar granule neuron precursors
A. Kenney, M. Cole, D. Rowitch
2003Development536 citations
Semantic Scholar
Breast cancer risk-associated SNPs modulate the affinity of chromatin for FOXA1 and alter gene expression
Richard Cowper-Sal·lari, Xiao-Yang Zhang, J. Wright, Swneke D. Bailey +4 more
2012Nature Genetics368 citations Open access
Semantic Scholar
Upregulation of c-MYC in cis through a Large Chromatin Loop Linked to a Cancer Risk-Associated Single-Nucleotide Polymorphism in Colorectal Cancer Cells
J. Wright, Seth Brown, M. Cole
2010Molecular and Cellular Biology261 citations Open access
Semantic Scholar
Subunit Composition and Substrate Specificity of a MOF-containing Histone Acetyltransferase Distinct from the Male-specific Lethal (MSL) Complex*
Yong Cai, Jingji Jin, S. Swanson, M. Cole +5 more
2009Journal of Biological Chemistry243 citations Open access
Semantic Scholar
Mechanism of transcriptional activation by the Myc oncoproteins.
V. Cowling, M. Cole
2006Seminars in Cancer Biology189 citations
Semantic Scholar
Nuclear receptor function requires a TFTC-type histone acetyl transferase complex.
J. Yanagisawa, H. Kitagawa, M. Yanagida, Osamu Wada +10 more
2002Molecules and Cells165 citations Open access
Semantic Scholar
Transcription-independent functions of MYC: regulation of translation and DNA replication
M. Cole, V. Cowling
2008Nature reviews. Molecular cell biology162 citations Open access
Semantic Scholar
The Myc Transactivation Domain Promotes Global Phosphorylation of the RNA Polymerase II Carboxy-Terminal Domain Independently of Direct DNA Binding
V. Cowling, M. Cole
2007Molecular and Cellular Biology156 citations Open access
Semantic Scholar
A Core MYC Gene Expression Signature Is Prominent in Basal-Like Breast Cancer but Only Partially Overlaps the Core Serum Response
S. Chandriani, E. Frengen, V. Cowling, S. Pendergrass +3 more
2009PLoS ONE144 citations Open access
Semantic Scholar
Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors.
Hua Li, P. Cherukuri, Na Li, V. Cowling +5 more
2007Cancer Research134 citations Open access
Semantic Scholar
Myc post-transcriptionally induces HIF1 protein and target gene expression in normal and cancer cells
Megan R. Doe, J. Ascano, Mandeep Kaur, M. Cole
2011Cancer Research127 citations Open access
Semantic Scholar
Nucleolin Is Required for RNA Polymerase I Transcription In Vivo
Brenden Rickards, S. J. Flint, M. Cole, G. Leroy
2006Molecular and Cellular Biology126 citations Open access
Semantic Scholar
The Action Mechanism of the Myc Inhibitor Termed Omomyc May Give Clues on How to Target Myc for Cancer Therapy
M. Savino, D. Annibali, Nicoletta Carucci, Emilia Favuzzi +4 more
2011PLoS ONE124 citations Open access
Semantic Scholar
c-Myc Transforms Human Mammary Epithelial Cells through Repression of the Wnt Inhibitors DKK1 and SFRP1
V. Cowling, C. D'Cruz, L. Chodosh, M. Cole
2007Molecular and Cellular Biology120 citations Open access
Semantic Scholar
A Conserved Myc Protein Domain, MBIV, Regulates DNA Binding, Apoptosis, Transformation, and G2 Arrest
V. Cowling, S. Chandriani, M. Whitfield, M. Cole
2006Molecular and Cellular Biology118 citations
Semantic Scholar
Myc protein is stabilized by suppression of a novel E3 ligase complex in cancer cells.
S. Choi, J. Wright, S. Gerber, M. Cole
2010Genes & Development116 citations Open access
Semantic Scholar
Overexpression and role of the ATPase and putative DNA helicase RuvB‐like 2 in human hepatocellular carcinoma
B. Rousseau, L. Ménard, Valérie Haurie, D. Taras +13 more
2007Hepatology116 citations
Semantic Scholar
TIP49, but not TRRAP, modulates c-Myc and E2F1 dependent apoptosis
Kerri A Dugan, M. Wood, M. Cole
2002Oncogene105 citations
Semantic Scholar
Strategically targeting MYC in cancer
Valeriya Posternak, M. Cole
2016F1000Research99 citations Open access
Semantic Scholar
Inhibition of the proteasome β2 site sensitizes triple-negative breast cancer cells to β5 inhibitors through a mechanism involving Nrf1 suppression
Emily Weyburne, Owen M. Wilkins, Zhe Sha, David A. Williams +6 more
2017Cell Chemical Biology98 citations Open access
Semantic Scholar
Faculty Opinions recommendation of DRUG DEVELOPMENT. Phthalimide conjugation as a strategy for in vivo target protein degradation.
M. Cole
201698 citations
Semantic Scholar
The Proto-oncogene c-myc Acts through the Cyclin-dependent Kinase (Cdk) Inhibitor p27Kip1to Facilitate the Activation of Cdk4/6 and Early G1Phase Progression*
A. Obaya, Iulia Kotenko, M. Cole, J. Sedivy
2002Journal of Biological Chemistry90 citations Open access
Semantic Scholar
Transcriptional activation by the Myc oncoprotein.
M. Cole, Mikhail A. Nikiforov
2006Current Topics in Microbiology and Immunology83 citations
Semantic Scholar
Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors
M. Cole, V. Cowling
2009Oncogene80 citations Open access
Semantic Scholar
Molecular and Cellular Pathobiology MYC Acts via the PTEN Tumor Suppressor to Elicit Autoregulation and Genome-Wide Gene Repression by Activation of the Ezh 2 Methyltransferase
Mandeep Kaur, M. Cole
201371 citations
Semantic Scholar
A Human T-Cell Lymphotropic Virus Type 1 Enhancer of Myc Transforming Potential Stabilizes Myc-TIP60 Transcriptional Interactions
Soumya Awasthi, Anima Sharma, Kasuen Wong, Junyu Zhang +16 more
2005Molecular and Cellular Biology71 citations Open access
Semantic Scholar
Evolution of the holozoan ribosome biogenesis regulon
Seth Brown, M. Cole, Albert J. Erives
2008BMC Genomics67 citations Open access
Semantic Scholar
Poly(ADP-ribose) polymerase-1 (PARP-1) pharmacogenetics, activity and expression analysis in cancer patients and healthy volunteers.
T. Zaremba, H. Thomas, M. Cole, S. Coulthard +2 more
2011Biochemical Journal65 citations Open access
Semantic Scholar
Reptin and Pontin function antagonistically with PcG and TrxG complexes to mediate Hox gene control
S. Diop, Karine Bertaux, Dasari Vasanthi, Ali Sarkeshik +9 more
2008EMBO Reports56 citations Open access
Semantic Scholar
Identification of RecQL1 as a Holliday junction processing enzyme in human cell lines
G. Leroy, R. Carroll, S. Kyin, M. Seki +1 more
2005Nucleic Acids Research54 citations Open access
Semantic Scholar
Polycomb mediates Myc autorepression and its transcriptional control of many loci in Drosophila.
J. Goodliffe, E. Wieschaus, M. Cole
2005Genes & Development51 citations Open access
Semantic Scholar
Burkitt’s lymphoma-associated c-Myc mutations converge on a dramatically altered target gene response and implicate Nol5a/Nop56 in oncogenesis
V. Cowling, S. Turner, M. Cole
2013Oncogene49 citations Open access
Semantic Scholar
25 years of the c-Myc oncogene.
M. Cole, M. Henriksson
2006Seminars in Cancer Biology46 citations
Semantic Scholar
An intergenic risk locus containing an enhancer deletion in 2q35 modulates breast cancer risk by deregulating IGFBP5 expression.
Asaf Wyszynski, Chi-Chen Hong, Kristina E. Lam, K. Michailidou +106 more
2016Human Molecular Genetics37 citations Open access
Semantic Scholar
Myc Regulation of mRNA Cap Methylation
V. Cowling, M. Cole
2010Genes & cancer37 citations Open access
Semantic Scholar
Turning the Tables: Myc Activates Wnt in Breast Cancer
V. Cowling, M. Cole
2007Cell Cycle36 citations Open access
Semantic Scholar
MYC Mediates mRNA Cap Methylation of Canonical Wnt/β-catenin Signaling Transcripts by Recruiting CDK7 and RNA Methyltransferase
Valeriya Posternak, Matthew H. Ung, Chao Cheng, M. Cole
2016Molecular Cancer Research34 citations Open access
Semantic Scholar
Layers of epistasis: genome-wide regulatory networks and network approaches to genome-wide association studies
Richard Cowper-Sal·lari, M. Cole, M. Karagas, M. Lupien +1 more
2010Wiley Interdisciplinary Reviews: Systems Biology and Medicine34 citations Open access
Semantic Scholar
Transcription Factor KLF5 Binds a Cyclin E1 Polymorphic Intronic Enhancer to Confer Increased Bladder Cancer Risk
Jillian M. Pattison, Valeriya Posternak, M. Cole
2016Molecular Cancer Research33 citations Open access
Semantic Scholar
The Mad and Myc Basic Domains Are Functionally Equivalent*
M. Nikiforov, N. Popov, Iulia Kotenko, M. Henriksson +1 more
2003Journal of Biological Chemistry32 citations Open access
Semantic Scholar
Formation of a structurally-stable conformation by the intrinsically disordered MYC:TRRAP complex
Edmond J Feris, J. Hinds, M. Cole
2019PLoS ONE30 citations Open access
Semantic Scholar
HS3ST1 Genotype Regulates Antithrombin’s Inflammomodulatory Tone and Associates with Atherosclerosis
N. Smits, Takashi Kobayashi, P. Srivastava, S. Skopelja +12 more
2017Matrix Biology30 citations Open access
Semantic Scholar
MYC association with cancer risk and a new model of MYC-mediated repression.
M. Cole
2014Cold Spring Harbor Perspectives in Medicine30 citations Open access
Semantic Scholar
PARP1 expression, activity and ex vivo sensitivity to the PARP inhibitor, talazoparib (BMN 673), in chronic lymphocytic leukaemia
A. Herriott, S. Tudhope, Gesa Junge, Natalie A. Rodrigues +12 more
2015OncoTarget29 citations Open access
Semantic Scholar
Doxorubicin-induced suppression of poly(ADP-ribose) polymerase-1 (PARP-1) activity and expression and its implication for PARP inhibitors in clinical trials
T. Zaremba, H. Thomas, M. Cole, E. Plummer +1 more
2010Cancer Chemotherapy and Pharmacology25 citations Open access
Semantic Scholar
Distal Interleukin-1β (IL-1β) Response Element of Human Matrix Metalloproteinase-13 (MMP-13) Binds Activator Protein 1 (AP-1) Transcription Factors and Regulates Gene Expression*
Adam C Schmucker, J. Wright, M. Cole, C. Brinckerhoff
2011Journal of Biological Chemistry23 citations Open access
Semantic Scholar
Coordinated regulation of Myc trans-activation targets by Polycomb and the Trithorax group protein Ash1
J. Goodliffe, M. Cole, E. Wieschaus
2007BMC Molecular Biology18 citations Open access
Semantic Scholar
SEC24A identified as an essential mediator of thapsigargin-induced cell death in a genome-wide CRISPR/Cas9 screen
Tamutenda Chidawanyika, Elizabeth Sergison, M. Cole, Kenneth M. K. Mark +1 more
2018Cell Death Discovery17 citations Open access
Semantic Scholar
Faculty Opinions recommendation of Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate.
M. Cole, Nadia Cumbal
201716 citations Open access
Semantic Scholar
Gene characteristics predicting missense, nonsense and frameshift mutations in tumor samples
I. Gorlov, C. Pikielny, H. R. Frost, Stephanie C. Her +6 more
2018BMC Bioinformatics12 citations Open access
Semantic Scholar

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