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R. Benarous · SciRah

Researcher profile · Semantic Scholar

R. Benarous

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R. Benarous — researcher profile on SciRah

h-index: 50
Works: 107
Citations: 8,362

Most-cited papers

A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif.
F. Margottin, S. Bour, H. Durand, L. Selig +5 more
1998Molecules and Cells735 citations Open access
Semantic Scholar
Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules.
S. Le Gall, L. Erdtmann, S. Bénichou, C. Berlioz-Torrent +4 more
1998Immunity419 citations Open access
Semantic Scholar
Vpu Antagonizes BST-2–Mediated Restriction of HIV-1 Release via β-TrCP and Endo-Lysosomal Trafficking
R. Mitchell, Chris Katsura, Mark Skasko, Kathleen Fitzpatrick +6 more
2009PLoS Pathogens357 citations Open access
Semantic Scholar
The F-box protein beta-TrCP associates with phosphorylated beta-catenin and regulates its activity in the cell.
M. Hart, J. Concordet, I. Lassot, I. Albert +7 more
1999Current Biology331 citations
Semantic Scholar
ATF4 Degradation Relies on a Phosphorylation-Dependent Interaction with the SCFβTrCPUbiquitin Ligase
I. Lassot, Emmanuel Ségéral, C. Berlioz-Torrent, H. Durand +4 more
2001Molecular and Cellular Biology277 citations Open access
Semantic Scholar
Article Transportin-SR2 Imports HIV into the Nucleus
F. Christ, W. Thys, J. De Rijck, R. Gijsbers +7 more
2008260 citations
Semantic Scholar
Integrase Mutants Defective for Interaction with LEDGF/p75 Are Impaired in Chromosome Tethering and HIV-1 Replication*
S. Emiliani, A. Mousnier, K. Busschots, M. Maroun +11 more
2005Journal of Biological Chemistry255 citations Open access
Semantic Scholar
The crystal structure of HIV-1 Nef protein bound to the Fyn kinase SH3 domain suggests a role for this complex in altered T cell receptor signaling.
S. Arold, Peet A. Franken, M. Strub, F. Hoh +3 more
1997Structure218 citations Open access
Semantic Scholar
The Interaction of LEDGF/p75 with Integrase Is Lentivirus-specific and Promotes DNA Binding*
K. Busschots, J. Vercammen, S. Emiliani, R. Benarous +3 more
2005Journal of Biological Chemistry217 citations Open access
Semantic Scholar
Interactions of the Cytoplasmic Domains of Human and Simian Retroviral Transmembrane Proteins with Components of the Clathrin Adaptor Complexes Modulate Intracellular and Cell Surface Expression of Envelope Glycoproteins
C. Berlioz-Torrent, B. Shacklett, L. Erdtmann, Lélia Delamarre +4 more
1999Journal of Virology200 citations Open access
Semantic Scholar
Human immunodeficiency virus type 1 Vpr protein binds to the uracil DNA glycosylase DNA repair enzyme
Mohamad Bouhamdan, Serge Benichou, Françoise Rey, Jean-Marc Navarro +7 more
1996Journal of Virology193 citations Open access
Semantic Scholar
The Interaction of Vpr with Uracil DNA Glycosylase Modulates the Human Immunodeficiency Virus Type 1 In Vivo Mutation Rate
L. Mansky, S. Prévéral, L. Selig, R. Benarous +1 more
2000Journal of Virology182 citations Open access
Semantic Scholar
Decreased expression of the two D2 dopamine receptor isoforms in bromocriptine-resistant prolactinomas.
L. Caccavelli, F. Féron, I. Morange, E. Rouer +5 more
1994Neuroendocrinology175 citations
Semantic Scholar
Requirement for SWI/SNF chromatin‐remodeling complex in Tat‐mediated activation of the HIV‐1 promoter
Céline Tréand, Isaure du Chéné, Vanessa Brès, Rosemary Kiernan +3 more
2006EMBO Journal173 citations Open access
Semantic Scholar
Tail-interacting protein TIP47 is a connector between Gag and Env and is required for Env incorporation into HIV-1 virions
S. López-Vergès, G. Camus, G. Blot, Roxane Beauvoir +2 more
2006Proceedings of the National Academy of Sciences of the United States of America159 citations Open access
Semantic Scholar
A Sequence in the N-terminal Region of Human Uracil-DNA Glycosylase with Homology to XPA Interacts with the C-terminal Part of the 34-kDa Subunit of Replication Protein A*
T. A. Nagelhus, T. Haug, Keshav K. Singh, K. Keshav +7 more
1997Journal of Biological Chemistry153 citations Open access
Semantic Scholar
Homo- and Heterodimerization of Peroxisomal ATP-binding Cassette Half-transporters*
Lang Liu, K. Janvier, V. Berteaux-Lecellier, N. Cartier +2 more
1999Journal of Biological Chemistry143 citations Open access
Semantic Scholar
Identification of the LEDGF/p75 binding site in HIV-1 integrase.
K. Busschots, A. Voet, M. de Maeyer, J. Rain +5 more
2007Journal of Molecular Biology142 citations
Semantic Scholar
Interaction with the p6 Domain of the Gag Precursor Mediates Incorporation into Virions of Vpr and Vpx Proteins from Primate Lentiviruses
L. Selig, J. Pagès, V. Tanchou, S. Prévéral +6 more
1999Journal of Virology142 citations Open access
Semantic Scholar
Targeting of the Human Immunodeficiency Virus Type 1 Envelope to the trans-Golgi Network through Binding to TIP47 Is Required for Env Incorporation into Virions and Infectivity
G. Blot, K. Janvier, S. Lepanse, R. Benarous +1 more
2003Journal of Virology141 citations Open access
Semantic Scholar
Inducible Degradation of IκBα by the Proteasome Requires Interaction with the F-box Protein h-βTrCP*
M. Kroll, F. Margottin, A. Kohl, P. Renard +5 more
1999Journal of Biological Chemistry131 citations Open access
Semantic Scholar
Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage
E. le Rouzic, Damien Bonnard, Sophie Chasset, J. Bruneau +18 more
2013Retrovirology126 citations Open access
Semantic Scholar
Physical and Functional Interaction of Nef with Lck
Y. Collette, H. Dutartre, A. Benziane, F. Ramos-Morales +3 more
1996Journal of Biological Chemistry126 citations Open access
Semantic Scholar
Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest
L. Selig, S. Bénichou, M. Rogel, Lily I. Wu +4 more
1997Journal of Virology125 citations Open access
Semantic Scholar
The Highly Conserved C-Terminal Dileucine Motif in the Cytosolic Domain of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Is Critical for Its Association with the AP-1 Clathrin Adapter
S. Wyss, C. Berlioz-Torrent, M. Böge, G. Blot +3 more
2001Journal of Virology122 citations Open access
Semantic Scholar
Two Dimerization Domains in the Trans-activation Response RNA-binding Protein (TRBP) Individually Reverse the Protein Kinase R Inhibition of HIV-1 Long Terminal Repeat Expression*
A. Daher, M. Longuet, D. Dorin, Florence Bois +8 more
2001Journal of Biological Chemistry114 citations Open access
Semantic Scholar
Mutation of a Conserved Residue (D123) Required for Oligomerization of Human Immunodeficiency Virus Type 1 Nef Protein Abolishes Interaction with Human Thioesterase and Results in Impairment of Nef Biological Functions
Lang-Xia Liu, N. Heveker, O. Fackler, S. Arold +7 more
2000Journal of Virology109 citations Open access
Semantic Scholar
p300 Modulates ATF4 Stability and Transcriptional Activity Independently of Its Acetyltransferase Domain*
I. Lassot, E. Estrabaud, S. Emiliani, M. Benkirane +2 more
2005Journal of Biological Chemistry108 citations Open access
Semantic Scholar
Lens Epithelium-derived Growth Factor/p75 Interacts with the Transposase-derived DDE Domain of PogZ*
K. Bartholomeeusen, F. Christ, Jelle Hendrix, J. Rain +5 more
2009Journal of Biological Chemistry99 citations Open access
Semantic Scholar
Structural basis for HIV‐1 DNA integration in the human genome, role of the LEDGF/P75 cofactor
Fabrice Michel, C. Crucifix, F. Granger, S. Eiler +11 more
2009EMBO Journal98 citations Open access
Semantic Scholar
von Hippel–Lindau binding protein 1-mediated degradation of integrase affects HIV-1 gene expression at a postintegration step
A. Mousnier, Nicole J. Kubat, Aurélie Massias-Simon, Emmanuel Ségéral +4 more
2007Proceedings of the National Academy of Sciences of the United States of America97 citations Open access
Semantic Scholar
Binding of HIV-1 Nef to a Novel Thioesterase Enzyme Correlates with Nef-mediated CD4 Down-regulation*
Lang Liu, F. Margottin, S. Le Gall, O. Schwartz +3 more
1997Journal of Biological Chemistry96 citations Open access
Semantic Scholar
Differential interaction of HIV-1 integrase and JPO2 with the C terminus of LEDGF/p75.
K. Bartholomeeusen, J. De Rijck, K. Busschots, L. Desender +5 more
2007Journal of Molecular Biology88 citations
Semantic Scholar
Mutational Analysis of Vpr-Induced G2Arrest, Nuclear Localization, and Cell Death in Fission Yeast
Mingzhong Chen, R. T. Elder, Min Yu, Maurice R. G. O'Gorman +4 more
1999Journal of Virology83 citations Open access
Semantic Scholar
HIV-1 Vpu Sequesters β-Transducin Repeat-containing Protein (βTrCP) in the Cytoplasm and Provokes the Accumulation of β-Catenin and Other SCFβTrCP Substrates*
C. Besnard‐Guérin, Nadia Belaidouni, I. Lassot, Emmanuel Ségéral +3 more
2004Journal of Biological Chemistry78 citations Open access
Semantic Scholar
Multiple mRNAs encode peripherin, a neuronal intermediate filament protein.
F. Landon, M. Lemonnier, R. Benarous, C. Huc +3 more
1989EMBO Journal76 citations Open access
Semantic Scholar
Regulated Degradation of the HIV-1 Vpu Protein through a βTrCP-Independent Pathway Limits the Release of Viral Particles
E. Estrabaud, E. le Rouzic, S. López-Vergès, Marina Morel +5 more
2007PLoS Pathogens64 citations Open access
Semantic Scholar
Inhibition of Early Steps of HIV-1 Replication by SNF5/Ini1*
M. Maroun, O. Delelis, G. Coadou, T. Bader +8 more
2006Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Quantitative analysis of transforming growth factor β1 messenger RNA in the liver of patients with chronic hepatitis C: Absence of correlation between high levels and severity of disease
D. Roulot, H. Durand, T. Coste, J. Rautureau +3 more
1995Hepatology63 citations Open access
Semantic Scholar
The highly conserved C-terminal dileucine motif in the cytosolic domain of the human immunodeficiency virus type 1 envelope glycoprotein is critical for its association with the AP-1 clathrin adaptor [correction of adapter].
S. Wyss, C. Berlioz-Torrent, M. Böge, G. Blot +3 more
2001Journal of Virology60 citations
Semantic Scholar
Directed expression of the HIV‐1 accessory protein Vpu in Drosophila fat‐body cells inhibits Toll‐dependent immune responses
F. Leulier, C. Marchal, I. Miletich, B. Limbourg-Bouchon +2 more
2003EMBO Reports59 citations Open access
Semantic Scholar
RASSF1C, an isoform of the tumor suppressor RASSF1A, promotes the accumulation of beta-catenin by interacting with betaTrCP.
E. Estrabaud, I. Lassot, G. Blot, E. le Rouzic +5 more
2007Cancer Research57 citations Open access
Semantic Scholar
Isolation and characterization of cDNAs encoding the heavy chain of human inter-alpha-trypsin inhibitor (I alpha TI): unambiguous evidence for multipolypeptide chain structure of I alpha TI.
Jean-Philippe Salier, M. Diarra‐Mehrpour, R. Sesboüé, J. Bourguignon +5 more
1987Proceedings of the National Academy of Sciences of the United States of America56 citations Open access
Semantic Scholar
HEED, the Product of the Human Homolog of the Murineeed Gene, Binds to the Matrix Protein of HIV-1*
Régis Peytavi, Saw-See Hong, B. Gay, A. D. d'Angeac +4 more
1999Journal of Biological Chemistry55 citations Open access
Semantic Scholar
Yeast two-hybrid detection of integrase-host factor interactions.
J. Rain, Alexandra Cribier, Annabelle Gérard, S. Emiliani +1 more
2009Methods53 citations
Semantic Scholar
Two Independent Regions of HIV‐1 Nef are Required for Connection with the Endocytic Pathway Through Binding to the μ1 Chain of AP1 Complex
Lars Erdtmann, K. Janvier, G. Raposo, H. Craig +5 more
2000Traffic : the International Journal of Intracellular Transport53 citations
Semantic Scholar
Human Dlg protein binds to the envelope glycoproteins of human T-cell leukemia virus type 1 and regulates envelope mediated cell-cell fusion in T lymphocytes
V. Blot, Lélia Delamarre, Fabien Perugi, D. Pham +6 more
2004Journal of Cell Science52 citations Open access
Semantic Scholar
HIV-1 Vpu sequesters beta-transducin repeat-containing protein (betaTrCP) in the cytoplasm and provokes the accumulation of beta-catenin and other SCFbetaTrCP substrates.
C. Besnard‐Guérin, Nadia Belaidouni, I. Lassot, Emmanuel Ségéral +3 more
2004Journal of Biological Chemistry50 citations
Semantic Scholar
Study of a growth hormone‐regulated protein secreted by rat hepatocytes: cDNA cloning, anti‐protease activity and regulation of its synthesis by various hormones.
A. le Cam, G. Pagès, Patrick Auberger, G. Le Cam +3 more
1987EMBO Journal50 citations Open access
Semantic Scholar
Overexpression of human βTrCP1 deleted of its F box induces tumorigenesis in transgenic mice
Nadia Belaidouni, M. Peuchmaur, C. Perret, Agnès Florentin +2 more
2005Oncogene49 citations Open access
Semantic Scholar

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