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A. Saxena · SciRah

Researcher profile · Semantic Scholar

A. Saxena

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A. Saxena — researcher profile on SciRah

h-index: 44
Works: 269
Citations: 7,050

Most-cited papers

Antiproliferative activity and induction of apoptosis by Annona muricata (Annonaceae) extract on human cancer cells
C. A. Pieme, Santosh Kumar, M. Dongmo, B. Moukette +3 more
2014BMC Complementary and Alternative Medicine165 citations Open access
Semantic Scholar
Synthesis of 3-O-propargylated betulinic acid and its 1,2,3-triazoles as potential apoptotic agents.
Rabiya Majeed, Payare L. Sangwan, Praveen K. Chinthakindi, Imran Khan +6 more
2013European journal of medicinal chemistry112 citations
Semantic Scholar
Triazole tethered isatin-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies.
H. Singh, J. Singh, M. Gupta, A. Saxena +3 more
2017Bioorganic & Medicinal Chemistry Letters107 citations
Semantic Scholar
Triazole tethered C5-curcuminoid-coumarin based molecular hybrids as novel antitubulin agents: Design, synthesis, biological investigation and docking studies.
H. Singh, M. Kumar, Kunal Nepali, M. Gupta +3 more
2016European journal of medicinal chemistry99 citations Open access
Semantic Scholar
Secalonic Acid-D Represses HIF1α/VEGF-Mediated Angiogenesis by Regulating the Akt/mTOR/p70S6K Signaling Cascade.
S. Guru, A. Pathania, Suresh Kumar, D. Ramesh +15 more
2015Cancer Research81 citations
Semantic Scholar
Anticancer activity of gallic acid template‐based benzylidene indanone derivative as microtubule destabilizer
Aastha Singh, Kaneez Fatima, Ankita Srivastava, Sadiya Khwaja +10 more
2016Chemical Biology and Drug Design76 citations
Semantic Scholar
Tailored polymer-lipid hybrid nanoparticles for the delivery of drug conjugate: dual strategy for brain targeting.
Udita Agrawal, G. Chashoo, P. R. Sharma, Ashok Kumar +2 more
2015Colloids and Surfaces B: Biointerfaces73 citations
Semantic Scholar
Critical role of three-dimensional tumorsphere size on experimental outcome.
Suraj Kumar Singh, Sabiya Abbas, A. Saxena, Swasti Tiwari +2 more
2020BioTechniques72 citations Open access
Semantic Scholar
Parthenium hysterophorus: A Probable Source of Anticancer, Antioxidant and Anti-HIV Agents
Shashank Kumar, G. Chashoo, A. Saxena, A. Pandey
2013BioMed Research International70 citations Open access
Semantic Scholar
Cytotoxic and antimicrobial activities of endophytic fungi isolated from Bacopa monnieri (L.) Pennell (Scrophulariaceae)
M. Katoch, Gurpreet Singh, Sadhna Sharma, Nidhi Gupta +2 more
2014BMC Complementary and Alternative Medicine69 citations Open access
Semantic Scholar
In Vitro and In Vivo Anticancer Activity of Root Extracts of Sansevieria liberica Gerome and Labroy (Agavaceae)
A. Akindele, Z. Wani, Sadhana Sharma, Girish B Mahajan +4 more
2015Evidence-Based Complementary and Alternative Medicine67 citations Open access
Semantic Scholar
Triazole linked mono carbonyl curcumin-isatin bifunctional hybrids as novel anti tubulin agents: Design, synthesis, biological evaluation and molecular modeling studies.
Sahil Sharma, M. Gupta, A. Saxena, P. Bedi
2015Bioorganic & Medicinal Chemistry62 citations
Semantic Scholar
Sphaeranthus indicus Induces Apoptosis Through Mitochondrial-Dependent Pathway in HL-60 Cells and Exerts Cytotoxic Potential on Several Human Cancer Cell Lines
A. Nahata, A. Saxena, Nitasha Suri, A. Saxena +1 more
2013Integrative Cancer Therapies53 citations Open access
Semantic Scholar
Synthesis, characterization and mechanistic-insight into the anti-proliferative potential of PLGA-gemcitabine conjugate.
Vaibhav Khare, Smit Kour, N. Alam, R. Dubey +7 more
2014International journal of pharmaceutics51 citations
Semantic Scholar
Cytotoxic and antimicrobial activity of selected Cameroonian edible plants
J. Dzoyem, S. Guru, C. A. Pieme, V. Kuete +4 more
2013BMC Complementary and Alternative Medicine51 citations Open access
Semantic Scholar
In vitro cytotoxicity, antimicrobial, and metal-chelating activity of triterpene saponins from tea seed grown in Kangra valley, India
R. Joshi, Swati Sood, Poonam Dogra, M. Mahendru +8 more
2013Medicinal Chemistry Research47 citations
Semantic Scholar
In Vitro Anticancer Activities of Anogeissus latifolia, Terminalia bellerica, Acacia catechu and Moringa oleiferna Indian Plants.
K. Diab, S. Guru, S. Bhushan, A. Saxena
2015Asian Pacific Journal of Cancer Prevention42 citations Open access
Semantic Scholar
Chalcone based azacarboline analogues as novel antitubulin agents: design, synthesis, biological evaluation and molecular modelling studies.
Sahil Sharma, C. Kaur, A. Budhiraja, Kunal Nepali +3 more
2014European journal of medicinal chemistry42 citations
Semantic Scholar
Novel Coronavirus 2019
Amit Kumar, A. Saxena, Gwo Giun Chris Lee, Amita Kashyap +1 more
2020SpringerBriefs in Applied Sciences and Technology40 citations
Semantic Scholar
A novel microtubule depolymerizing colchicine analogue triggers apoptosis and autophagy in HCT‐116 colon cancer cells
Ashok Kumar, Baljinder Singh, P. R. Sharma, Sandip B. Bharate +2 more
2016Cell Biochemistry and Function40 citations
Semantic Scholar
In vitro anticancer activity of extracts of Mentha Spp. against human cancer cells.
Vikas Sharma, S. Hussain, Moni Gupta, A. Saxena
2014Indian Journal of Biochemistry & Biophysics40 citations
Semantic Scholar
Dual targeted polymeric nanoparticles based on tumor endothelium and tumor cells for enhanced antitumor drug delivery.
Madhu Gupta, G. Chashoo, P. R. Sharma, A. Saxena +3 more
2014Molecular Pharmaceutics40 citations
Semantic Scholar
Synthesis and characterization of 2-substituted benzimidazoles and their evaluation as anticancer agent.
M. Azam, A. A. Khan, S. Al-Resayes, M. Islam +5 more
2015Spectrochimica Acta Part A - Molecular and Biomolecular Spectroscopy39 citations
Semantic Scholar
Isolation, Cytotoxicity Evaluation and HPLC-Quantification of the Chemical Constituents from Prangos pabularia
S. Farooq, Shakeel-u-Rehman, N. A. Dangroo, D. Priya +5 more
2014PLoS ONE39 citations Open access
Semantic Scholar
Cell cycle inhibitory activity of Piper longum against A549 cell line and its protective effect against metal-induced toxicity in rats.
A. Sharma, Shashank Kumar, G. Chashoo, A. Saxena +1 more
2014Indian Journal of Biochemistry & Biophysics37 citations
Semantic Scholar
Synthesis of a novel series of artemisinin dimers with potent anticancer activity involving Sonogashira cross-coupling reaction.
Pori Buragohain, Bishwajit Saikia, Naresh Surineni, N. C. Barua +2 more
2014Bioorganic & Medicinal Chemistry Letters34 citations
Semantic Scholar
Long-circulatory nanoparticles for gemcitabine delivery: Development and investigation of pharmacokinetics and in-vivo anticancer efficacy.
Vaibhav Khare, Amarinder Singh, Girish B Mahajan, N. Alam +8 more
2016European Journal of Pharmaceutical Sciences31 citations
Semantic Scholar
Colchicine derivatives with potent anticancer activity and reduced P-glycoprotein induction liability.
Baljinder Singh, Anil Kumar, P. Joshi, S. Guru +15 more
2015Organic and biomolecular chemistry30 citations
Semantic Scholar
Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer.
A. K. Qazi, A. Hussain, Saima Khan, M. Aga +8 more
2015Cancer Letters27 citations
Semantic Scholar
β-Ionone derived chalcones as potent antiproliferative agents.
Vishal B. Sharma, A. Chaudhary, Saroj Arora, A. Saxena +1 more
2013European journal of medicinal chemistry25 citations
Semantic Scholar
Synthesis of 1,2,3-triazole tethered bifunctional hybrids by click chemistry and their cytotoxic studies
Jagjeet Singh, Sahil Sharma, A. Saxena, Kunal Nepali +1 more
2013Medicinal Chemistry Research23 citations
Semantic Scholar
Fruits and barks extracts of Zanthozyllum heitzii a spice from Cameroon induce mitochondrial dependent apoptosis and Go/G1 phase arrest in human leukemia HL-60 cells
C. A. Pieme, Guru Kumar Santosh, E. M. Tekwu, T. Askun +4 more
2014Biological Research22 citations Open access
Semantic Scholar
Cell specific apoptosis by RLX is mediated by NFκB in human colon carcinoma HCT-116 cells
A. K. Qazi, A. Hussain, M. Aga, Shakir Ali +5 more
2014BMC Cell Biology21 citations Open access
Semantic Scholar
Autologous Bone Marrow Aspirate Therapy for Skin Tissue Engineering and Tissue Regeneration
G. Gupta, K. Karki, P. Jain, A. Saxena
2017Advances in wound care20 citations Open access
Semantic Scholar
PI3K target based novel cyano derivative of betulinic acid induces its signalling inhibition by down‐regulation of pGSK3β and cyclin D1 and potentially checks cancer cell proliferation
Rabiya Majeed, A. Hussain, Payare L. Sangwan, Praveen K. Chinthakindi +5 more
2016Molecular Carcinogenesis20 citations
Semantic Scholar
Thiazolidinone Constraint Combretastatin Analogs as Novel Antitubulin Agents: Design, Synthesis, Biological Evaluation and Docking Studies.
Sahil Sharma, M. Gupta, A. Saxena, P. Bedi
2017Anti-Cancer Agents in Medicinal Chemistry19 citations
Semantic Scholar
Role of autophagy in regulation of glioma stem cells population during therapeutic stress.
Sabiya Abbas, Suraj Kumar Singh, A. Saxena, Swasti Tiwari +2 more
2020Journal of Stem Cells and Regenerative Medicine18 citations Open access
Semantic Scholar
The Role of p53 Gene in Cervical Carcinogenesis
Garima, S. Pandey, L. Pandey, A. Saxena +1 more
2016Journal of Obstetrics and Gynecology of India17 citations Open access
Semantic Scholar
Immunosuppressive potential of Botryosphaeria dothidea, an endophyte isolated from Kigelia africana
M. Katoch, A. Khajuria, Parduman R. Sharma, A. Saxena
2015Pharmaceutical Biology16 citations Open access
Semantic Scholar
Epigarcinol and isogarcinol isolated from the root of Garcinia ovalifolia induce apoptosis of human promyelocytic leukemia (HL-60 cells)
C. A. Pieme, Pathaleon Ambassa, E. Yankep, A. Saxena
2015BMC Research Notes15 citations Open access
Semantic Scholar
In vitro cytotoxic activity of leaves extracts of Holarrhena antidysenterica against some human cancer cell lines.
Vikas Sharma, S. Hussain, M. Bakshi, N. Bhat +1 more
2014Indian Journal of Biochemistry & Biophysics15 citations
Semantic Scholar
Reversal of boswellic acid analog BA145 induced caspase dependent apoptosis by PI3K inhibitor LY294002 and MEK inhibitor PD98059
A. Pathania, Amit Joshi, Suresh Kumar, S. Guru +10 more
2013Apoptosis15 citations
Semantic Scholar
In vitro cytotoxicity of the polar extracts of Potentilla fulgens L. against human cancer cell lines: Detection and isolation of bioactive phenolics
J. M. H. Anal, Rabiya Majeed, G. Bez, D. Syiem +2 more
201413 citations
Semantic Scholar
Targetting Cdks in Cancer: An Overview and New Insights
G. Chashoo, A. Saxena
201413 citations Open access
Semantic Scholar
Synthesis and cytotoxicity evaluation of regioisomeric substituted N-phenyl-3′-(chrom-4-one-3-yl)-isoxazolidines: induction of apoptosis through a mitochondrial-dependent pathway
Gagandeep Singh, A. Kaur, Vishal B. Sharma, Nitasha Suri +3 more
201313 citations
Semantic Scholar
β-Ionone derived apoptosis inducing endoperoxides; Discovery of potent leads for anticancer agents.
Vishal B. Sharma, A. Chaudhry, G. Chashoo, R. Arora +3 more
2014European journal of medicinal chemistry12 citations
Semantic Scholar
Anagallis arvensis Induces Apoptosis in HL-60 Cells Through ROS-Mediated Mitochondrial Pathway
S. Agrawal, M. Agrawal, P. R. Sharma, K. Ahmad +3 more
2020Nutrition and Cancer11 citations
Semantic Scholar
In Search of Novel Coronavirus 19 Therapeutic Targets
Jyothsna Gundlapally, Amit Kumar, Amita Kashyap, A. Saxena +1 more
2020Helix9 citations Open access
Semantic Scholar
Cytotoxic Compounds from the Leaves of Garcinia polyantha
A. Lannang, Simplice J. N. Tatsimo, Hugues Fouotsa, J. Dzoyem +2 more
2014Chemistry and Biodiversity9 citations
Semantic Scholar
In human alleles specific variation of MTHFR C677T and A1298C associated "risk factor" for the development of ovarian cancer.
Anupama Singh, S. Pandey, L. Pandey, A. Saxena
2015Journal of experimental therapeutics and oncology8 citations
Semantic Scholar

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