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A. Franzen · SciRah

Researcher profile · Semantic Scholar

A. Franzen

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A. Franzen — researcher profile on SciRah

h-index: 16
Works: 34
Citations: 745

Most-cited papers

Free-Circulating Methylated DNA in Blood for Diagnosis, Staging, Prognosis, and Monitoring of Head and Neck Squamous Cell Carcinoma Patients: An Observational Prospective Cohort Study.
A. Schröck, Annette Leisse, L. de Vos, H. Gevensleben +14 more
2017Clinical Chemistry108 citations Open access
Semantic Scholar
FGFR1 expression levels predict BGJ398-sensitivity of FGFR1-dependent head and neck squamous cell cancers
F. Göke, A. Franzen, T. Hinz, Lindsay A. Marek +21 more
2015Clinical Cancer Research83 citations Open access
Semantic Scholar
Expression and role of the embryonic protein SOX2 in head and neck squamous cell carcinoma.
A. Schröck, M. Bode, F. Göke, P. Bareiss +12 more
2014Carcinogenesis70 citations Open access
Semantic Scholar
PD-L1 (CD274) and PD-L2 (PDCD1LG2) promoter methylation is associated with HPV infection and transcriptional repression in head and neck squamous cell carcinomas
A. Franzen, Timo J. Vogt, Tim Müller, Jörn Dietrich +7 more
2017OncoTarget57 citations Open access
Semantic Scholar
Fibroblast growth factor receptor 1 amplification is a common event in squamous cell carcinoma of the head and neck
F. Göke, M. Bode, A. Franzen, R. Kirsten +14 more
2013Modern Pathology55 citations Open access
Semantic Scholar
Rationale for treatment of metastatic squamous cell carcinoma of the lung using fibroblast growth factor receptor inhibitors.
F. Göke, A. Franzen, R. Menon, D. Goltz +11 more
2012Chest47 citations
Semantic Scholar
Sex Determining Region Y-Box 2 (SOX2) Amplification Is an Independent Indicator of Disease Recurrence in Sinonasal Cancer
A. Schröck, F. Göke, Patrick L. Wagner, M. Bode +11 more
2013PLoS ONE44 citations Open access
Semantic Scholar
Comparison of quantification algorithms for circulating cell-free DNA methylation biomarkers in blood plasma from cancer patients
L. de Vos, H. Gevensleben, A. Schröck, A. Franzen +3 more
2017Clinical Epigenetics41 citations Open access
Semantic Scholar
Fibroblast growth factor receptor‐1 as a potential therapeutic target in sinonasal cancer
A. Schröck, F. Göke, Patrick L. Wagner, M. Bode +9 more
2014Head and Neck32 citations
Semantic Scholar
Fibroblast Growth Factor Receptor 1 as a Putative Therapy Target in Colorectal Cancer
F. Göke, Antonia Göke, A. von Mässenhausen, A. Franzen +11 more
2013Digestion30 citations Open access
Semantic Scholar
CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma
F. Hoffmann, A. Franzen, L. de Vos, Lennert Wuest +15 more
2023Clinical Epigenetics23 citations Open access
Semantic Scholar
PITX2 and PANCR DNA methylation predicts overall survival in patients with head and neck squamous cell carcinoma
V. Sailer, E. Holmes, H. Gevensleben, D. Goltz +8 more
2016OncoTarget21 citations Open access
Semantic Scholar
CTLA4, PD-1, PD-L1, PD-L2, TIM-3, TIGIT, and LAG3 DNA Methylation Is Associated With BAP1-Aberrancy, Transcriptional Activity, and Overall Survival in Uveal Melanoma
L. de Vos, Tzaitel Maria Carrillo Cano, Romina Zarbl, N. Klümper +9 more
2022Journal of immunotherapy18 citations
Semantic Scholar
FGFR1 as a novel prognostic and predictive biomarker in squamous cell cancers of the lung and the head and neck area.
A. von Mässenhausen, A. Franzen, L. Heasley, S. Perner
2013Annals of Translational Medicine18 citations
Semantic Scholar
Circulating Cell-Free SEPT9 DNA Methylation in Blood Is a Biomarker for Minimal Residual Disease Detection in Head and Neck Squamous Cell Carcinoma Patients.
D. Dietrich, S. Weider, L. de Vos, Timo J. Vogt +12 more
2023Clinical Chemistry16 citations
Semantic Scholar
Intragenic DNA methylation of PITX1 and the adjacent long non-coding RNA C5orf66-AS1 are prognostic biomarkers in patients with head and neck squamous cell carcinomas
V. Sailer, Arthur Charpentier, J. Dietrich, Timo J. Vogt +4 more
2018PLoS ONE16 citations Open access
Semantic Scholar
PITX3 DNA methylation is an independent predictor of overall survival in patients with head and neck squamous cell carcinoma
V. Sailer, E. Holmes, H. Gevensleben, D. Goltz +7 more
2017Clinical Epigenetics14 citations Open access
Semantic Scholar
Evaluation of FGFR3 as a Therapeutic Target in Head and Neck Squamous Cell Carcinoma
A. von Mässenhausen, M. Deng, H. Billig, Angela Queisser +10 more
2016Targeted oncology14 citations
Semantic Scholar
DNA Methylation and mRNA Expression of OX40 (TNFRSF4) and GITR (TNFRSF18, AITR) in Head and Neck Squamous Cell Carcinoma Correlates With HPV Status, Mutational Load, an Interferon-γ Signature, Signatures of Immune Infiltrates, and Survival
S. Loick, Anne Fröhlich, J. Gabrielpillai, A. Franzen +7 more
2021Journal of immunotherapy12 citations
Semantic Scholar
PD-1, CTLA4, PD-L1 and PD-L2 DNA methylation in papillary thyroid carcinoma.
L. de Vos, Jörn Dietrich, S. Strieth, F. Bootz +2 more
2020Immunotherapy11 citations
Semantic Scholar
Circulating Cell-Free SHOX2 DNA Methylation Is a Predictive, Prognostic, and Monitoring Biomarker in Adjuvant and Palliative Anti-PD-1-Treated Melanoma.
S. Fietz, Eric Diekmann, L. de Vos, Romina Zarbl +10 more
2024Clinical Chemistry5 citations Open access
Semantic Scholar
A new bright-field dual-colour chromogenic and silver in situ hybridization method for the detection of FGFR1 gene copy number status
D. Boehm, W. Vogel, A. Franzen, Andreas Schrock +4 more
2014Virchows Archiv5 citations
Semantic Scholar
814 Rationale for Treatment of Metastatic Squamous Cell Carcinoma of the Lung Using FGFR1 Inhibitors
F. Göke, A. Franzen, R. Menon, D. Goltz +6 more
20124 citations Open access
Semantic Scholar
30-day postoperative mortality and the effects of hospital preparedness during the COVID-19 pandemic: a pooled analysis of prospective international cohort studies.
D. Nepogodiev, S. Kamarajah, A. Bhangu, Radhika Aacharya +496 more
2026The Lancet Regional Health - Europe3 citations Open access
Semantic Scholar
Adjuvant and palliative anti-PD-1 treatment response monitoring in head and neck squamous cell Carcinoma patients by circulating Cell-Free SEPT9 DNA Methylation in blood
Dimo Dietrich, Franz-Georg Bauernfeind, M. Färber, P. Brossart +2 more
202495th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e. V., Bonn0 citations
Semantic Scholar
Minimal Residual Disease Detection in Head and Neck Squamous Cell Carcinoma Patients by Circulating Cell-Free SEPT9 DNA Methylation in Blood
S. Strieth, D. Dietrich, P. Brossart, A. Franzen
202394th Annual Meeting German Society of Oto-Rhino-Laryngology, Head and Neck Surgery e.V., Bonn0 citations
Semantic Scholar
Investigation of TIGIT methylation in head and neck squamous cell carcinomas
T. Vogt, A. Franzen, F. Bootz, D. Dietrich
2019Laryngo-Rhino-Otologie0 citations Open access
Semantic Scholar
Circulating cell-free methylated DNA in blood from head and neck squamous cell carcinoma patients for post-surgical residual tumor detection and therapy response monitoring
A. Franzen, S. Weider, L. de Vos, F. Bootz +1 more
2019Laryngo-Rhino-Otologie0 citations Open access
Semantic Scholar
Zirkulierende zellfreie methylierte DNA im Blut von Kopf-Hals-Tumorpatienten zur Bestimmung postoperativer Tumorresiduen und Therapieansprechen
A. Franzen, S. Weider, L. de Vos, F. Bootz +1 more
2019Laryngo-Rhino-Otologie0 citations Open access
Semantic Scholar
PITX3 DNA methylation is an independent predictor of overall survival in patients with head and neck squamous cell carcinoma
V. Sailer, E. Holmes, H. Gevensleben, D. Goltz +7 more
2017Clinical Epigenetics0 citations Open access
Semantic Scholar
3 D NA methylation is an independent predictor of overall survival in patients with head and neck squamous cell carcinoma
V. Sailer, E. Holmes, H. Gevensleben, D. Goltz +7 more
20170 citations
Semantic Scholar
629: Expression and role of the embryonic protein SOX2 in head and neck squamous cell carcinoma
A. Schröck, M. Bode, A. Franzen, L. Heasley +3 more
20140 citations
Semantic Scholar
818 FGFR1 Amplification in Metastatic Squamous Cell Carcinoma of the Head and Neck – a Potential Target for a Rational Therapy?
F. Göke, A. Franzen, R. Menon, R. Kirsten +5 more
20120 citations
Semantic Scholar
East Meets West:Strengthening the Traditional Doctor-Patient Relationship with Alternative Medical Techniques
A. Franzen
20040 citations
Semantic Scholar

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