Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

H. Biersack · SciRah

Researcher profile · Semantic Scholar

H. Biersack

Share profile

H. Biersack — researcher profile on SciRah

h-index: 14
Works: 51
Citations: 750

Most-cited papers

Allogeneic stem cell transplantation after a fludarabine/busulfan-based reduced-intensity conditioning in patients with myelodysplastic syndrome or secondary acute myeloid leukemia
N. Kroger, M. Bornhäuser, G. Ehninger, R. Schwerdtfeger +7 more
2003Annals of Hematology95 citations
Semantic Scholar
Value of allogeneic versus autologous stem cell transplantation and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial
T. de Witte, A. Hagemeijer, S. Suciu, A. Belhabri +16 more
2010Haematologica76 citations Open access
Semantic Scholar
Active heterodimers are formed from human DNA topoisomerase II alpha and II beta isoforms.
H. Biersack, S. Jensen, Irina Gromova, I. S. Nielsen +2 more
1996Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Genomic insights into the pathogenesis of Epstein–Barr virus-associated diffuse large B-cell lymphoma by whole-genome and targeted amplicon sequencing
N. Gebauer, A. Künstner, J. Ketzer, H. Witte +16 more
2021Blood Cancer Journal49 citations Open access
Semantic Scholar
Prevalence of targetable oncogenic mutations and genomic alterations in Epstein–Barr virus-associated diffuse large B-cell lymphoma of the elderly
N. Gebauer, J. Gebauer, T. T. Hardel, V. Bernard +5 more
2015Leukemia and Lymphoma45 citations
Semantic Scholar
Reduced Risk for Molecular Disease in Patients with Chronic Myeloid Leukemia after Transplantation from a KIR-Mismatched Donor
A. Elmaagacli, H. Ottinger, M. Koldehoff, R. Peceny +5 more
2005Transplantation41 citations Open access
Semantic Scholar
A retrospective comparison of autologous and unrelated donor hematopoietic cell transplantation in myelodysplastic syndrome and secondary acute myeloid leukemia: a report on behalf of the Chronic Leukemia Working Party of the European Group for Blood and Marrow Transplantation (EBMT)
H. Al-Ali, R. Brand, A. van Biezen, J. Finke +8 more
2007Leukemia39 citations
Semantic Scholar
Detection of Human Topoisomerase IIα in Cell Lines and Tissues: Characterization of Five Novel Monoclonal Antibodies
U. Kellner, H. Heidebrecht, P. Rudolph, H. Biersack +7 more
1997Journal of Histochemistry and Cytochemistry38 citations Open access
Semantic Scholar
Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action
T. Bartscht, Benjamin Rosien, D. Rades, R. Kaufmann +4 more
2015Molecular Cancer36 citations Open access
Semantic Scholar
Sequential high-dose cytarabine and mitoxantrone (S-HAM) versus standard double induction in acute myeloid leukemia—a phase 3 study
J. Braess, S. Amler, K. Kreuzer, K. Spiekermann +41 more
2018Leukemia29 citations Open access
Semantic Scholar
Impact of treatment variability and clinicopathological characteristics on survival in patients with Epstein‐Barr‐Virus positive diffuse large B cell lymphoma
H. Witte, H. Merz, H. Biersack, V. Bernard +6 more
2020British Journal of Haematology28 citations
Semantic Scholar
The Glasgow Prognostic Score at Diagnosis Is a Predictor of Clinical Outcome in Patients with Multiple Myeloma Undergoing Autologous Haematopoietic Stem Cell Transplantation
H. Witte, Bastian Bonorden, A. Riecke, H. Biersack +7 more
2020Cancers18 citations Open access
Semantic Scholar
Inhibition of TGF-β Signaling in Tumor Cells by Small Molecule Src Family Kinase Inhibitors.
T. Bartscht, Benjamin Rosien, D. Rades, R. Kaufmann +3 more
2017Anti-Cancer Agents in Medicinal Chemistry15 citations
Semantic Scholar
A drug-resistant variant of topoisomerase II alpha in human HL-60 cells exhibits alterations in catalytic pH optimum, DNA binding and sub-nuclear distribution.
Fritz Boege, Eigil Kjeldsen, Frank Gieseler, Jan Alsner +1 more
1993European Journal of Biochemistry15 citations
Semantic Scholar
Characterization of DNA topoisomerase II alpha/beta heterodimers in HeLa cells.
Irina I. Gromova, H. Biersack, S. Jensen, O. Nielsen +2 more
1998Biochemistry14 citations
Semantic Scholar
The Glasgow prognostic score at diagnosis is an independent predictor of survival in advanced stage classical Hodgkin lymphoma
H. Witte, H. Biersack, S. Kopelke, D. Rades +5 more
2019British Journal of Haematology12 citations Open access
Semantic Scholar
Favorable prognostic impact of RAS mutation status in multiple myeloma treated with high-dose melphalan and autologous stem cell support in the era of novel agents: a single center perspective
N. Gebauer, H. Biersack, A. Czerwińska, Janina Schemme +6 more
2016Leukemia and Lymphoma12 citations
Semantic Scholar
Indolent lymphoma with composite histology and simultaneous transformation at initial diagnosis exhibit clinical features similar to de novo diffuse large B-cell lymphoma
H. Witte, H. Biersack, S. Kopelke, D. Rades +4 more
2018OncoTarget11 citations Open access
Semantic Scholar
Exhaustion of tumour‐infiltrating T‐cell receptor repertoire diversity is an age‐dependent indicator of immunological fitness independently predictive of clinical outcome in Burkitt lymphoma
Johannes Rieken, V. Bernard, H. Witte, W. Peter +8 more
2020British Journal of Haematology10 citations Open access
Semantic Scholar
Lenalidomide, adriamycin, dexamethasone for induction followed by stem-cell transplant in newly diagnosed myeloma
S. Knop, C. Langer, M. Engelhardt, L. Mügge +17 more
2017Leukemia10 citations
Semantic Scholar
High Efficacy and Significantly Shortened Neutropenia Of Dose-Dense S-HAM As Compared To Standard Double Induction: First Results Of a Prospective Randomized Trial (AML-CG 2008)
J. Braess, K. Kreuzer, K. Spiekermann, H. Lindemann +38 more
201310 citations
Semantic Scholar
Cytotoxicity of anthracyclines: Correlation with cellular uptake, intracellular distribution and DNA binding
Frank Gieseler, H. Biersack, T. Brieden, J. Manderscheid +1 more
2005Annals of Hematology10 citations
Semantic Scholar
Trofosfamide in the treatment of elderly or frail patients with diffuse large B-cell lymphoma
H. Witte, A. Riecke, T. Mayer, T. Bartscht +6 more
2018Journal of Cancer Research and Clinical Oncology8 citations Open access
Semantic Scholar
Activating mutations affecting the NF-kappa B pathway and EZH2-mediated epigenetic regulation are rare events in primary mediastinal large B-cell lymphoma.
N. Gebauer, T. T. Hardel, J. Gebauer, V. Bernard +6 more
2014Anticancer Research8 citations
Semantic Scholar
Active heterodimers are formed from human DNA topoisomerase IIa and 11(3 isoforms
H. Biersack, S. Jensen, I. Gromova, I. S. Nielsen +2 more
20058 citations
Semantic Scholar
Nuclear Topoisomerase II Activity Changes During HL-60 Leukemic Cell Differentiation: Alterations in Drug Sensitivity and pH Dependency.
Frank Gieseler, Fritz Boege, H. Biersack, Birgit Spohn +2 more
1991Leukemia and Lymphoma8 citations
Semantic Scholar
Use of anion-exchange chromatography and chromatofocusing to reveal the structural and functional heterogeneity of topoisomerase II in a HL-60 cell line resistant to multi-drug treatment.
Fritz Boege, Frank Gieseler, H. Biersack, M. Clark
1991Journal of Chromatography A8 citations
Semantic Scholar
Activation of topoisomerase II during partial purification by heparin-Sepharose chromatography.
Fritz Boege, Frank Gieseler, Michaela Müller, H. Biersack +1 more
1992Journal of Chromatography A6 citations
Semantic Scholar
Response to Lenalidomide, Doxorubicin and Dexamethasone (RAD) in Newly Diagnosed Multiple Myeloma Is Independent of Cytogenetic Risk and Retained after Double Stem Cell Transplant
S. Knop, C. Langer, M. Engelhardt, L. Mügge +16 more
20145 citations
Semantic Scholar
Analysis of functional domain organization in DNA topoisomerase II from humans and Saccharomyces cerevisiae
S. Jensen, Anni H. Andersen, Eigil Kjeldsen, H. Biersack +4 more
1996Molecular and Cellular Biology5 citations Open access
Semantic Scholar
TGF-β Signal Transduction in Pancreatic Carcinoma Cells is Sensitive to Inhibition by the Src Tyrosine Kinase Inhibitor AZM475271.
T. Bartscht, Benjamin Rosien, D. Rades, R. Kaufmann +3 more
2017Anti-Cancer Agents in Medicinal Chemistry4 citations
Semantic Scholar
Drug-sensitivity and DNA-binding of a subform of topoisomerase II alpha in resistant human HL-60 cells.
Fritz Boege, H. Biersack, P. Meyer
1994Acta oncologica4 citations Open access
Semantic Scholar
Characterization of Human Leukemic HL-60 Sublines as a Model for Primary and Secondary Resistance Against Cytostatics
E. Gieseler, F. Boege, R. Erttmann, H. Tony +3 more
19924 citations
Semantic Scholar
Single nucleotide polymorphisms in TP53 but not KRAS or MDM2 are predictive of clinical outcome in multiple myeloma treated with high-dose melphalan and autologous stem cell support
N. Gebauer, H. Biersack, A. Czerwińska, Janina Schemme +6 more
2016Leukemia and Lymphoma3 citations
Semantic Scholar
Rapid purification of DNA topoisomerase II containing a hexahistidine tag by metal ion affinity chromatography.
H. Biersack, S. Jensen, Ole Westergaard
1999Methods in molecular biology3 citations
Semantic Scholar
Different functional states of topoisomerase II can be discriminated by orthovanadate sensitivity in multi-drug resistant human leukemic cells.
Fritz Boege, Frank Gieseler, H. Biersack, P. Meyer
1993Leukemia and Lymphoma3 citations
Semantic Scholar
The measurement of nuclear topoisomerase II inhibition in vitro: a possible tool for detecting resistance on a subcellular level in haematopoietic malignancies.
Fritz Boege, Frank Gieseler, H. Biersack, P. Meyer
1992European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies3 citations
Semantic Scholar
Systemic Inflammation and Tumour-Infiltrating T-Cell Receptor Repertoire Diversity Are Predictive of Clinical Outcome in High-Grade B-Cell Lymphoma with MYC and BCL2 and/or BCL6 Rearrangements
Vito Olschewski, H. Witte, V. Bernard, K. Steinestel +7 more
2021Cancers2 citations Open access
Semantic Scholar
Lenalidomide, Adriamycin and Dexamethasone (RAD) Versus Bortezomib, Lenalidomide and Dexamethasone (VRD) in Newly Diagnosed Multiple Myeloma (MM) - Post-Induction Response and MRD Results By Flow Cytometry and NGS from a Phase 3 Randomized Controlled Clinical Trial (RCT)
T. Stübig, C. Langer, M. Engelhardt, L. Mügge +28 more
2018Blood1 citations Open access
Semantic Scholar
The Integrated Glasgow Prognostic- and Cytogenetic Risk Score (CytoGPS) at Diagnosis Is a Strong and Independent Predictor of Survival in Transplant-Eligible Patients with Multiple Myelom
H. Witte, H. Biersack, A. Riecke, Bastian Bonorden +7 more
2018Blood1 citations
Semantic Scholar
Lenalidomide, adriamycin and dexamethasone (RAD) versus bortezomib, lenalidomide and dexamethasone (VRD) as induction regimens in newly diagnosed multiple myeloma - first results from the DSMM XIV study
S. Knop, C. Langer, M. Engelhardt, T. Stübig +25 more
20171 citations
Semantic Scholar
Real life experience with ATRA-arsenic trioxide based regimen in acute promyelocytic leukemia - results of the prospective German intergroup Napoleon registry
U. Platzbecker, E. Lengfelder, K. Goetze, C. Röllig +43 more
20161 citations Open access
Semantic Scholar
Punktionen: Knochenmarkpunktion
H. Biersack
2015DGIM Innere Medizin1 citations
Semantic Scholar
Dasatinib blocks transcriptional and promigratory responses to transforming growth factor-beta in pancreatic adenocarcinoma cells through inhibition of Smad signalling: implications for in vivo mode of action
T. Bartscht, Benjamin Rosien, D. Rades, R. Kaufmann +4 more
2015Molecular Cancer0 citations Open access
Semantic Scholar
Value of allogeneic stem cell transplantation (SCT) versus autologous SCT and chemotherapy in patients with myelodysplastic syndromes and secondary acute myeloid leukemia. Final results of a prospective randomized European Intergroup Trial
T. de Witte, A. Hagemeijer, S. Suciu, A. Belhabri +24 more
20100 citations
Semantic Scholar
A method for producing a frame-like structural member
H. Biersack, T. Gilbert, Dieter Jungert
20080 citations
Semantic Scholar
Opening roof for a convertible
Dominik Beierl, H. Biersack
20070 citations
Semantic Scholar
Allogeneic SCT planned in CR-1 after intensive chemotherapy in patients with bad prognosis MDS results in better outcome in the intermediate/high-risk cytogenetic group: a study by the EORTC, EBMT, SAKK, HOVON and GIMEMA Leukemia Groups
T. de Witte, A. Hagemeijer, S. Suciu, A. Belhabri +17 more
20060 citations
Semantic Scholar
Improved Outcome of Patients with Invasive Pulmonary Fungal Infection Complicated by Respiratory Failure Due to the Use of New Antimycotis Agens and Early Tracheostomy after Allogeneic Transplantation.
M. Koldehoff, A. Elmaagacli, N. Steckel, R. Trenschel +4 more
20050 citations
Semantic Scholar
Absract
M. Kaszkin, V. Kinzel, Karl Maly, Irina Bichler +496 more
2005Journal of Cancer Research and Clinical Oncology0 citations Open access
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

N. Gebauer×13
Invite
N. Gebauer — researcher profile on SciRah
V. Bernard×12
Invite
V. Bernard — researcher profile on SciRah
H. Lehnert×12
Invite
H. Lehnert — researcher profile on SciRah
D. Rades×11
Invite
D. Rades — researcher profile on SciRah

×9

Invite

H. Witte — researcher profile on SciRah

Invite

H. Merz — researcher profile on SciRah

Invite

Fritz Boege — researcher profile on SciRah

Invite

A. Feller — researcher profile on SciRah

Invite

S. Jensen — researcher profile on SciRah

Invite

T. Bartscht — researcher profile on SciRah

Invite

A. Reichle — researcher profile on SciRah

K. Schäfer-Eckart×5

Invite

K. Schäfer-Eckart — researcher profile on SciRah