J. Rock

Most-cited papers

Basal cells as stem cells of the mouse trachea and human airway epithelium
J. Rock, M. Onaitis, E. Rawlins, Yun Lu +4 more
2009Proceedings of the National Academy of Sciences of the United States of America1,509 citations Open access
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Multiple stromal populations contribute to pulmonary fibrosis without evidence for epithelial to mesenchymal transition
J. Rock, C. Barkauskas, Michael J. Cronce, Yan Xue +4 more
2011Proceedings of the National Academy of Sciences of the United States of America972 citations Open access
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Distinct stem cells contribute to mammary gland development and maintenance
Alexandra Van Keymeulen, A. Rocha, M. Ousset, Benjamin Beck +5 more
2011Nature870 citations
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Repair and regeneration of the respiratory system: complexity, plasticity, and mechanisms of lung stem cell function
B. Hogan, C. Barkauskas, H. Chapman, J. Epstein +14 more
2014Cell Stem Cell824 citations Open access
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Airway basal stem cells: a perspective on their roles in epithelial homeostasis and remodeling
J. Rock, S. Randell, B. Hogan
2010Disease Models & Mechanisms734 citations Open access
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Lineage-negative Progenitors Mobilize to Regenerate Lung Epithelium after Major Injury
Andrew E. Vaughan, A. Brumwell, Ying Xi, J. Gotts +9 more
2014Nature633 citations Open access
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Notch-dependent differentiation of adult airway basal stem cells
J. Rock, Xia Gao, Yan Xue, S. Randell +2 more
2011Cell Stem Cell442 citations Open access
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Epithelial progenitor cells in lung development, maintenance, repair, and disease.
J. Rock, B. Hogan
2011Annual Review of Cell and Developmental Biology413 citations
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Expression of anoctamin 1/TMEM16A by interstitial cells of Cajal is fundamental for slow wave activity in gastrointestinal muscles
S. Hwang, P. Blair, F. Britton, K. O'Driscoll +6 more
2009Journal of Physiology411 citations Open access
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The Cellular and Physiological Basis for Lung Repair and Regeneration: Past, Present, and Future
M. Basil, Jeremy B. Katzen, A. Engler, M. Guo +12 more
2020Cell Stem Cell349 citations Open access
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Profiling human breast epithelial cells using single cell RNA sequencing identifies cell diversity
Q. Nguyen, Nicholas Pervolarakis, Kerrigan Blake, Dennis Ma +13 more
2018Nature Communications343 citations Open access
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Calcium-activated chloride channel TMEM16A modulates mucin secretion and airway smooth muscle contraction
Fen Huang, Hong-Kang Zhang, Meng Wu, Huang-He Yang +15 more
2012Proceedings of the National Academy of Sciences of the United States of America332 citations Open access
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Studies on expression and function of the TMEM16A calcium-activated chloride channel
Fen Huang, J. Rock, B. Harfe, T. Cheng +3 more
2009Proceedings of the National Academy of Sciences of the United States of America308 citations Open access
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Evidence for type II cells as cells of origin of K-Ras–induced distal lung adenocarcinoma
Xia Xu, J. Rock, Yun Lu, C. Futtner +4 more
2012Proceedings of the National Academy of Sciences of the United States of America295 citations Open access
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TMEM16A Induces MAPK and Contributes Directly to Tumorigenesis and Cancer Progression
U. Duvvuri, D. Shiwarski, D. Xiao, C. Bertrand +13 more
2012Cancer Research269 citations Open access
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Human distal lung maps and lineage hierarchies reveal a bipotent progenitor
Preetish Kadur Lakshminarasimha Murthy, Vishwaraj Sontake, A. Tata, Yoshihiko Kobayashi +12 more
2022Nature266 citations Open access
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Transmembrane Protein 16A (TMEM16A) Is a Ca2+-regulated Cl– Secretory Channel in Mouse Airways*
J. Rock, W. O'Neal, S. Gabriel, S. Randell +3 more
2009Journal of Biological Chemistry243 citations Open access
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Loss of TMEM16A Causes a Defect in Epithelial Ca2+-dependent Chloride Transport*
J. Ousingsawat, Joana R. Martins, R. Schreiber, J. Rock +2 more
2009Journal of Biological Chemistry236 citations Open access
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Evidence That SOX2 Overexpression Is Oncogenic in the Lung
Yun Lu, C. Futtner, J. Rock, Xia Xu +3 more
2010PLoS ONE230 citations Open access
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Telomere dysfunction in alveolar epithelial cells causes lung remodeling and fibrosis.
R. Naikawadi, Supparerk Disayabutr, B. Mallavia, Matthew L Donne +5 more
2016JCI Insight229 citations Open access
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The transmembrane protein TMEM16A is required for normal development of the murine trachea.
J. Rock, C. Futtner, B. Harfe
2008Developmental Biology228 citations Open access
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Recruited monocytes and Th2 cytokine signaling promote lung regeneration following pneumonectomy
A. Lechner, Ian H. Driver, Jinwoo Lee, Carmen M. Conroy +3 more
2017Cell Stem Cell216 citations Open access
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Prospective isolation of NKX2-1–expressing human lung progenitors derived from pluripotent stem cells
F. Hawkins, P. Kramer, Anjali Jacob, Ian H. Driver +15 more
2017Journal of Clinical Investigation206 citations Open access
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Tmem16A Encodes the Ca2+-activated Cl− Channel in Mouse Submandibular Salivary Gland Acinar Cells*
V. Romanenko, M. Catalán, David A. Brown, Ilva Putzier +6 more
2010Journal of Biological Chemistry189 citations Open access
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TMEM16 Proteins Produce Volume-regulated Chloride Currents That Are Reduced in Mice Lacking TMEM16A*
J. Almaça, Yuemin Tian, Fadi Aldehni, J. Ousingsawat +5 more
2009Journal of Biological Chemistry181 citations Open access
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Spontaneous activity of cochlear hair cells triggered by fluid secretion mechanism in adjacent support cells
Han-Chin Wang, Chun-Chieh Lin, Rocky Cheung, YingXin Zhang-Hooks +4 more
2015Cell132 citations Open access
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The Ca2+-gated channel TMEM16A amplifies capillary pericyte contraction and reduces cerebral blood flow after ischemia
Nils Korte, Zeki Ilkan, C. L. Pearson, Thomas Pfeiffer +6 more
2022Journal of Clinical Investigation114 citations Open access
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Epithelial Chloride Transport by CFTR Requires TMEM16A
R. Benedetto, J. Ousingsawat, Podchanart Wanitchakool, Yong Zhang +5 more
2017Scientific Reports112 citations Open access
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mTORC1 activation during repeated regeneration impairs somatic stem cell maintenance
S. Haller, Subir Kapuria, Rebeccah R. Riley, Monique N. O'Leary +9 more
2017Cell Stem Cell108 citations Open access
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Ano1, a Ca2+‐activated Cl− channel, coordinates contractility in mouse intestine by Ca2+ transient coordination between interstitial cells of Cajal
R. Singh, S. Gibbons, Siva Arumugam Saravanaperumal, P. Du +11 more
2014Journal of Physiology101 citations Open access
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Electrical Slow Waves in the Mouse Oviduct Are Dependent upon a Calcium Activated Chloride Conductance Encoded by Tmem16a1
R. Dixon, G. Hennig, S. Baker, F. Britton +4 more
2012Biology of Reproduction98 citations Open access
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Stem cells of the adult lung: their development and role in homeostasis, regeneration, and disease
C. Wansleeben, C. Barkauskas, J. Rock, B. Hogan
2013Wiley Interdisciplinary Reviews: Developmental Biology95 citations
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Ano1 as a regulator of proliferation
J. Stanich, S. Gibbons, S. Eisenman, M. Bardsley +4 more
2011American Journal of Physiology - Gastrointestinal and Liver Physiology88 citations Open access
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Anoctamins support calcium-dependent chloride secretion by facilitating calcium signaling in adult mouse intestine
R. Schreiber, Diana Faria, B. Skryabin, Podchanart Wanitchakool +2 more
2014Pflügers Archiv: European Journal of Physiology80 citations
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Persistent Pathology in Influenza-Infected Mouse Lungs.
Cindy M. Kanegai, Ying Xi, Matthew L Donne, J. Gotts +7 more
2016American Journal of Respiratory Cell and Molecular Biology73 citations Open access
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Anoctamins
K. Kunzelmann, Yuemin Tian, Joana Raquel Martins, D. Faria +6 more
2011Pflügers Archiv: European Journal of Physiology72 citations
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The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function.
Diana Faria, J. Rock, A. M. Romão, F. Schweda +8 more
2014Kidney International71 citations Open access
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Expression of TMEM16 paralogs during murine embryogenesis
J. Rock, B. Harfe
2008Developmental Dynamics71 citations Open access
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Lung megakaryocytes display distinct transcriptional and phenotypic properties.
Anthony K. Yeung, C. Villacorta-Martin, S. Hon, J. Rock +1 more
2020Blood Advances70 citations Open access
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Neurotransmitter map of the asymmetric dorsal habenular nuclei of zebrafish
Tagide N. deCarvalho, Abhignya Subedi, J. Rock, B. Harfe +4 more
2014Genesis63 citations Open access
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An Lmx1b-miR135a2 Regulatory Circuit Modulates Wnt1/Wnt Signaling and Determines the Size of the Midbrain Dopaminergic Progenitor Pool
A. Anderegg, Hsin-Pin Lin, Jun-An Chen, Giuliana Caronia-Brown +7 more
2013PLoS Genetics62 citations Open access
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Endogenous lung regeneration: potential and limitations.
J. Rock, M. Königshoff
2012American Journal of Respiratory and Critical Care Medicine60 citations
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Ano1 mediates pressure-sensitive contraction frequency changes in mouse lymphatic collecting vessels
S. Zawieja, Jorge Castorena, P. Gui, Min Li +4 more
2019The Journal of General Physiology50 citations Open access
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The cells and conductance mediating cholinergic neurotransmission in the murine proximal stomach
T. Sung, S. Hwang, S. D. Koh, Y. Bayguinov +7 more
2018Journal of Physiology44 citations Open access
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ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter
Caroline A. Cobine, E. Hannah, M.-H. Zhu, H. E. Lyle +4 more
2017Journal of Physiology44 citations Open access
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Airway-Associated Macrophages in Homeostasis and Repair
A. Engler, A. Ysasi, R. Pihl, C. Villacorta-Martin +7 more
2020bioRxiv43 citations Open access
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Expression patterns of the Tmem16 gene family during cephalic development in the mouse.
A. Gritli-Linde, Forugh Vaziri Sani, J. Rock, Kristina Hallberg +3 more
2009Gene Expression Patterns43 citations
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Conditional knockout of TMEM16A/anoctamin1 abolishes the calcium-activated chloride current in mouse vomeronasal sensory neurons
Asma Amjad, Andres Hernandez-Clavijo, S. Pifferi, D. Maurya +4 more
2015The Journal of General Physiology34 citations Open access
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Evidence for lung epithelial stem cell niches
Matthew L Donne, A. Lechner, J. Rock
2015BMC Developmental Biology32 citations Open access
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Identification of genes expressed in the mouse limb using a novel ZPA microarray approach.
J. Rock, M. C. López, H. Baker, B. Harfe
2007Gene Expression Patterns29 citations
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