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A. Leal · SciRah

Researcher profile · Semantic Scholar

A. Leal

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A. Leal — researcher profile on SciRah

h-index: 14
Works: 52
Citations: 779

Most-cited papers

Non-V600 BRAF Mutations Define a Clinically Distinct Molecular Subtype of Metastatic Colorectal Cancer.
J. Jones, L. Renfro, H. Al-Shamsi, A. Schrock +14 more
2017Journal of Clinical Oncology278 citations Open access
Semantic Scholar
NCCTG N08CA (Alliance): The use of Glutathione for Prevention of Paclitaxel/Carboplatin Induced Peripheral Neuropathy: A Phase III Randomized, Double-Blind Placebo-Controlled Study
A. Leal, R. Qin, P. Atherton, P. Haluska +7 more
2014Cancer83 citations Open access
Semantic Scholar
Fosaprepitant-induced Phlebitis: A Focus on Patients receiving Doxorubicin/Cyclophosphamide therapy
A. Leal, Kunal C. Kadakia, S. Looker, Crystal R Hilger +7 more
2013Supportive Care in Cancer49 citations Open access
Semantic Scholar
Anthropometric, medical history and lifestyle risk factors for myeloproliferative neoplasms in The Iowa Women’s Health Study (IWHS) cohort
A. Leal, Carrie A Thompson, Alice H. Wang, R. Vierkant +5 more
2013International Journal of Cancer45 citations Open access
Semantic Scholar
Clinical Development of Immunotherapy for Deficient Mismatch Repair Colorectal Cancer.
Jane V. Thomas, A. Leal, M. Overman
2020Clinical colorectal cancer39 citations
Semantic Scholar
An analysis of fosaprepitant-induced venous toxicity in patients receiving highly emetogenic chemotherapy
Livia Hegerova, A. Leal, D. Grendahl, D. Seisler +4 more
2014Supportive Care in Cancer30 citations Open access
Semantic Scholar
ATM kinase inhibitor AZD0156 in combination with irinotecan and 5-fluorouracil in preclinical models of colorectal cancer
S. L. Davis, S. Hartman, S. Bagby, Marina I. Schlaepfer +11 more
2022BMC Cancer24 citations Open access
Semantic Scholar
WEE1 Inhibition in Combination With Targeted Agents and Standard Chemotherapy in Preclinical Models of Pancreatic Ductal Adenocarcinoma
S. Hartman, S. Bagby, Betelehem Yacob, Dennis M. Simmons +9 more
2021Frontiers in Oncology23 citations Open access
Semantic Scholar
Outcome of neoadjuvant treatment for pancreatic cancer in elderly patients: comparative, observational cohort study.
A. Oba, Y.-Ha Wu, C. Lieu, C. Meguid +18 more
2021British Journal of Surgery21 citations
Semantic Scholar
A phase I, first-in-human study of TAK-164, an antibody–drug conjugate, in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C
R. Kim, A. Leal, A. Parikh, D. Ryan +8 more
2023Cancer Chemotherapy and Pharmacology19 citations Open access
Semantic Scholar
Ten-Year Trends in Antiemetic Prescribing in Patients Receiving Highly Emetogenic Chemotherapy.
C. O'Sullivan, H. Van Houten, L. Sangaralingham, A. Leal +5 more
2018The Journal of the National Comprehensive Cancer Network19 citations Open access
Semantic Scholar
Widespread Use of Complementary and Alternative Medicine (CAM) among Non-Hodgkin Lymphoma (NHL) Survivors
Sarah Rausch Osian, A. Leal, Cristine Allmer, M. Maurer +8 more
2014Leukemia and Lymphoma15 citations Open access
Semantic Scholar
Cabozantinib sensitizes microsatellite stable colorectal cancer to immune checkpoint blockade by immune modulation in human immune system mouse models
J. Lang, A. Leal, J. Marín-Jiménez, S. Hartman +15 more
2022Frontiers in Oncology14 citations Open access
Semantic Scholar
Variability of Performance Status Assessment between Patients with Hematologic Malignancies and Their Physicians
A. Leal, Cristine Allmer, M. Maurer, T. Shanafelt +3 more
2017Leukemia and Lymphoma14 citations Open access
Semantic Scholar
AMPLIFY-201, a first-in-human safety and efficacy trial of adjuvant ELI-002 2P immunotherapy for patients with high-relapse risk with KRAS G12D- or G12R-mutated pancreatic and colorectal cancer.
E. O'Reilly, Z. Wainberg, C. Weekes, Muhammad Furqan +11 more
2023Journal of Clinical Oncology13 citations Open access
Semantic Scholar
Antiemetic prescribing practices using a computerized physician order entry system
Kunal C. Kadakia, A. Leal, D. Seisler, R. Qin +4 more
2013Supportive Care in Cancer12 citations Open access
Semantic Scholar
Response to pembrolizumab in patients with mismatch repair deficient (dMMR) colorectal cancer (CRC).
A. Leal, J. Paludo, Heidi D. Finnes, A. Grothey
201710 citations
Semantic Scholar
High incidence of prolonged rectal bleeding and advanced stage cancer in early-onset colorectal cancer patients
G. Sandhu, R. Anders, P. Blatchford, A. Walde +23 more
20208 citations Open access
Semantic Scholar
Impact of Radiation Dose on Postoperative Complications in Esophageal and Gastroesophageal Junction Cancers
N. Kastelowitz, Megan D. Marsh, M. McCarter, R. Meguid +18 more
2021Frontiers in Oncology7 citations Open access
Semantic Scholar
Antibody drug conjugates under investigation in phase I and phase II clinical trials for gastrointestinal cancer
A. Leal, A. Krishnamurthy, L. Head, W. Messersmith
2018Expert Opinion on Investigational Drugs7 citations
Semantic Scholar
Hormonal and Reproductive Factors and Risk of Myeloproliferative Neoplasms in Postmenopausal Women
A. Leal, C. Thompson, Alice H. Wang, R. Vierkant +5 more
2015Cancer Epidemiology, Biomarkers and Prevention7 citations Open access
Semantic Scholar
Phase 1 study to determine the safety and dosing of autologous PBMCs modified to present HPV16 antigens (SQZ-PBMC-HPV) in HLA-A*02+ patients with HPV16+ solid tumors
A. Jimeno, J. Baranda, W. Iams, J. C. Park +20 more
2023Investigational new drugs5 citations Open access
Semantic Scholar
High incidence of advanced stage cancer and prolonged rectal bleeding history before diagnosis in young-onset patients with colorectal cancer.
G. Sandhu, R. Anders, A. Walde, A. Leal +16 more
2019Journal of Clinical Oncology5 citations
Semantic Scholar
Commonality and clinical, pathological, and prognostic characteristics of non-V600E BRAF mutations (BRAFMut) in metastatic colorectal cancers (mCRC) compared to V600 BRAFMut CRCs.
J. Jones, B. Kipp, A. Leal, J. Voss +3 more
20165 citations
Semantic Scholar
Correction to: A phase I, first-in-human study of TAK-164, an antibody–drug conjugate, in patients with advanced gastrointestinal cancers expressing guanylyl cyclase C
R. Kim, A. Leal, A. Parikh, D. Ryan +8 more
2023Cancer Chemotherapy and Pharmacology4 citations Open access
Semantic Scholar
Response to pembrolizumab in patients with mismatch repair deficient (dMMR) metastatic colorectal cancer (mCRC).
A. Leal, J. Paludo, Heidi D. Finnes, A. Grothey
20174 citations
Semantic Scholar
Widespread use of complementary and alternative medicine (CAM) among non-Hodgkin lymphoma (NHL) survivors.
A. Leal, Cristine Allmer, M. Maurer, J. Cerhan +7 more
20124 citations
Semantic Scholar
A phase 1 study of TAK-164, an anti-guanylyl cyclase C (GCC) antibody-drug conjugate (ADC), in patients (pts) with advanced gastrointestinal (GI) cancers expressing GCC.
R. Kim, J. Cleary, A. Leal, A. Parikh +8 more
20213 citations
Semantic Scholar
Tissue tumor mutational burden (TMB) as a biomarker of efficacy with immune checkpoint inhibitors (ICI) in metastatic gastrointestinal (mGI) cancers.
R. Lentz, Tyler Friedrich, Jun-Xiao Hu, A. Leal +5 more
20213 citations
Semantic Scholar
Neoadjuvant treatment of localized pancreatic adenocarcinoma.
A. Leal, W. Messersmith, C. Lieu
2021Journal of Gastrointestinal Oncology2 citations Open access
Semantic Scholar
The role of neoadjuvant chemotherapy in elderly patients with borderline or locally advanced pancreatic cancer: Is it safe and feasible?
A. Oba, C. Lieu, C. Meguid, S. L. Davis +11 more
20202 citations
Semantic Scholar
Abstract 6647: Sensitizing microsatellite stable colorectal cancer to immune checkpoint therapy utilizing Wnt pathway inhibition
S. Bagby, S. Hartman, N. Navarro, Betelehem Yacob +10 more
2020Immunology2 citations
Semantic Scholar
New Adjuvant Trial Designs in Colon Cancer
A. Leal, J. Hubbard, D. Sargent, A. Grothey
2015Current Colorectal Cancer Reports2 citations
Semantic Scholar
Abstract A109: Cabozantinib sensitizes microsatellite stable colorectal cancer to immune checkpoint inhibition by immune modulation in humanized mouse models
J. Lang, A. Leal, Sarah Hartmann, J. Marín-Jiménez +8 more
2020Poster Presentations - Proffered Abstracts1 citations
Semantic Scholar
Abstract P6-11-18: Ten year trends in antiemetic prescribing in cancer patients receiving highly emetogenic chemotherapy (HEC)
C. O'Sullivan, H. V. Van Houten, L. Sangaralingham, A. Leal +5 more
20181 citations
Semantic Scholar
Phase I trial of TAS-102 and concurrent radiation therapy for patients with locally recurrent, unresectable or metastatic, rectal cancer.
J. Hubbard, A. Leal, C. Hallemeier, D. Ahn +4 more
20181 citations
Semantic Scholar
Breast Cancer Survivorship Care Variations Between Adjuvant Chemotherapy Regimens
A. Leal, H. Van Houten, L. Sangaralingham, R. Freedman +10 more
2017Clinical Breast Cancer1 citations Open access
Semantic Scholar
Abstract 2536: Anthropometric, medical history and lifestyle risk factors for myeloproliferative neoplasms in the Iowa Women's Health Study (IWHS) cohort.
A. Leal, C. Thompson, Alice H. Wang, R. Vierkant +4 more
20131 citations
Semantic Scholar
Impact of early-onset colorectal cancer on utilization of chemotherapy and outcomes in patients with stage II disease.
J. Leary, Jun-Xiao Hu, S. Davis, A. Leal +9 more
2023Journal of Clinical Oncology0 citations Open access
Semantic Scholar
Trial in progress: A phase II study (with safety run-in) of evorpacept (ALX148), cetuximab, and pembrolizumab in patients with refractory microsatellite-stable metastatic colorectal cancer (AGICC-ALX148 21CRC01).
R. Lentz, Jun-Xiao Hu, P. Blatchford, T. Pitts +8 more
2023Journal of Clinical Oncology0 citations
Semantic Scholar
898 Triple therapy (binimetinib, bevacizumab, pembrolizumab) modulates the tumor immune microenvironment in microsatellite stable colorectal cancer PDXs in a humanized mice model
J. Lang, Adrian Dominquez, M. Lewis, Sarah Hartmann +9 more
2022Regular and Young Investigator Award Abstracts0 citations Open access
Semantic Scholar
Utility of chemotherapy given before and/or after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for appendiceal adenocarcinoma with peritoneal metastases.
Tyler Friedrich, Jun-Xia Hu, R. Lentz, A. Leal +7 more
20210 citations
Semantic Scholar
A single-institution experience using total neoadjuvant therapy to treat locally advanced rectal cancer.
Tyler Friedrich, A. Glode, R. Lentz, W. Herter +12 more
20210 citations
Semantic Scholar
An assessment of dose intensity of the TNT approach on outcomes in locally advanced rectal cancer.
A. Glode, Tyler Friedrich, G. Sandhu, W. Herter +14 more
20200 citations
Semantic Scholar
Abstract 1315: Combination of Wee1 inhibition with targeted and standard chemotherapy in preclinical models of pancreatic ductal adenocarcinoma
S. Hartman, S. Bagby, Betelehem Yacob, Dennis M. Simmons +7 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Operative outcomes following neoadjuvant chemotherapy and stereotactic body radiation therapy (sbrt) for borderline resectable and locally advanced pancreatic cancer
S. Zakem, A. Mueller, C. Meguid, R. Torphy +13 more
2019HPB0 citations Open access
Semantic Scholar
Abstract 3855: Preclinical investigation of novel ALDH1A1 inhibitors in pancreatic cancer
Betelehem Yacob, J. Arcaroli, Maraake Taddese, T. Pitts +6 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Impact of radiation dose during neoadjuvant chemoradiation on postoperative complications in esophageal (EC) and gastroesophageal junction cancers (GEJC).
N. Kastelowitz, Megan D. Marsh, M. McCarter, R. Meguid +13 more
2019Journal of Clinical Oncology0 citations
Semantic Scholar
Impact of multidisciplinary management in the diagnosis and treatment of neuroendocrine tumors (NET).
G. Sandhu, A. Krishnamurthy, Reed Weiss, C. Meguid +16 more
2018Journal of Clinical Oncology0 citations
Semantic Scholar
Special Issues in Young Women with Triple-Negative Breast Cancer
N. Duma, C. O'Sullivan, K. Ruddy, A. Leal
20180 citations
Semantic Scholar

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