D. Jansen

Most-cited papers

1. KDM5 histone demethylases repress immune response via suppression of STING

   Li-Zhen Wu, Jian Cao, Wesley L. Cai, Sabine M. Lang +20 more

   2018PLoS Biology154 citations Open access

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2. Structural basis for KDM5A histone lysine demethylase inhibition by diverse compounds

   J. Horton, Xu Liu, M. Gale, Li-Zhen Wu +19 more

   2016Cell Chemical Biology89 citations Open access

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3. Synthesis of medicinally relevant terpenes: reducing the cost and time of drug discovery

   D. Jansen, Ryan A. Shenvi

   2014Future Medicinal Chemistry65 citations Open access

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4. A stereoselective hydroamination transform to access polysubstituted indolizidines.

   S. Pronin, M. G. Tabor, D. Jansen, Ryan A. Shenvi

   2012Journal of the American Chemical Society56 citations

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5. Synthesis of (-)-neothiobinupharidine.

   D. Jansen, Ryan A. Shenvi

   2013Journal of the American Chemical Society52 citations

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6. KDM5B Promotes Drug Resistance by Regulating Melanoma Propagating Cell Subpopulations

   Xiao-Ni Liu, Shang-Min Zhang, M. McGeary, Irina Krykbaeva +8 more

   2018Molecular Cancer Therapeutics49 citations Open access

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7. Intramolecular azide-alkyne [3 + 2] cycloaddition: versatile route to new heterocyclic structural scaffolds.

   Rong-Ti Li, D. Jansen, A. Datta

   2009Organic and biomolecular chemistry48 citations

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8. Combined immuno- and non-radioactive hybridocytochemistry on cells and tissue sections: influence of fixation, enzyme pre-treatment, and choice of chromogen on detection of antigen and DNA sequences.

   H. Mullink, J. Walboomers, T. Tadema, D. Jansen +1 more

   1989Journal of Histochemistry and Cytochemistry47 citations

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9. Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5A

   J. Horton, C. Woodcock, Qin Chen, Xu Liu +19 more

   2018Journal of Medicinal Chemistry26 citations Open access

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10. Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites

    D. Dorjsuren, Richard T. Eastman, K. Wicht, D. Jansen +26 more

    2021Scientific Reports22 citations Open access

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11. Synthesis and Sulfur Electrophilicity of the Nuphar Thiaspirane Pharmacophore

    N. Tada, D. Jansen, Matthew P. Mower, Megan M. Blewett +4 more

    2016ACS Central Science16 citations Open access

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12. Small Molecule Inhibitors of Activation-Induced Deaminase Decrease Class Switch Recombination in B Cells.

    J. Alvarez-Gonzalez, Adam Yasgar, R. Maul, A. E. Rieffer +11 more

    2021ACS Pharmacology & Translational Science9 citations Open access

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13. Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5A

    J. Horton, Xu Liu, Li-Zhen Wu, Kai Zhang +18 more

    2018Journal of Medicinal Chemistry7 citations Open access

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