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David Mark Howard · SciRah

Researcher profile · Semantic Scholar

David Mark Howard

King's College London

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David Mark Howard — researcher profile on SciRah

ORCID iD 0000-0002-6005-1972

h-index: 34
Works: 132
Citations: 6,255

Most-cited papers

Genome-wide meta-analysis of depression identifies 102 independent variants and highlights the importance of the prefrontal brain regions
David Mark Howard, M. Adams, T. Clarke, J. Hafferty +34 more
2019Nature Neuroscience2,303 citations Open access
Semantic Scholar
Genome-wide association study of alcohol consumption and genetic overlap with other health-related traits in UK Biobank (N=112 117)
T. Clarke, M. Adams, G. Davies, David Mark Howard +9 more
2017Molecular Psychiatry378 citations Open access
Semantic Scholar
Association analysis in over 329,000 individuals identifies 116 independent variants influencing neuroticism
M. Luciano, S. Hagenaars, G. Davies, W. Hill +12 more
2017Nature Genetics369 citations Open access
Semantic Scholar
Genome-wide association study meta-analysis of the Alcohol Use Disorder Identification Test (AUDIT) in two population-based cohorts
S. Sanchez-Roige, A. Palmer, P. Fontanillas, S. Elson +8 more
2018bioRxiv211 citations Open access
Semantic Scholar
Epigenetic measures of ageing predict the prevalence and incidence of leading causes of death and disease burden
R. Hillary, A. Stevenson, D. McCartney, A. Campbell +10 more
2020Clinical Epigenetics177 citations Open access
Semantic Scholar
Exploration of haplotype research consortium imputation for genome-wide association studies in 20,032 Generation Scotland participants
R. Nagy, T. Boutin, J. Marten, J. Huffman +21 more
2017Genome Medicine122 citations Open access
Semantic Scholar
A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank
Xue-Yi Shen, David Mark Howard, M. Adams, W. Hill +5 more
2019Nature Communications108 citations Open access
Semantic Scholar
A meta-analysis of genome-wide association studies of epigenetic age acceleration
J. Gibson, Tom C. Russ, T. Clarke, David Mark Howard +14 more
2019bioRxiv108 citations Open access
Semantic Scholar
Bivariate genome-wide association analyses of the broad depression phenotype combined with major depressive disorder, bipolar disorder or schizophrenia reveal eight novel genetic loci for depression
A. Amare, Ahmad Vaez, Y. Hsu, N. Direk +7 more
2019Molecular Psychiatry92 citations Open access
Semantic Scholar
Dosage, Intensity, and Frequency of Language Therapy for Aphasia: A Systematic Review–Based, Individual Participant Data Network Meta-Analysis
M. Brady, Myzoon Ali, Kathryn VandenBerg, Linda J. Williams +64 more
2021Stroke79 citations Open access
Semantic Scholar
Genome-wide association study of antidepressant treatment resistance in a population-based cohort using health service prescription data and meta-analysis with GENDEP
E. Wigmore, J. Hafferty, L. Hall, David Mark Howard +20 more
2019The Pharmacogenomics Journal74 citations Open access
Semantic Scholar
Epigenetic prediction of major depressive disorder
M. Barbu, Xue-Yi Shen, R. Walker, David Mark Howard +9 more
2019Molecular Psychiatry73 citations Open access
Semantic Scholar
Resting-State Connectivity and Its Association With Cognitive Performance, Educational Attainment, and Household Income in the UK Biobank
Xue-Yi Shen, S. Cox, M. Adams, David Mark Howard +6 more
2018Biological Psychiatry: Cognitive Neuroscience and Neuroimaging73 citations Open access
Semantic Scholar
A sex-specific genome-wide association study of depression phenotypes in UK Biobank
P. Silveira, I. Pokhvisneva, David Mark Howard, M. Meaney
2022Molecular Psychiatry69 citations Open access
Semantic Scholar
3GENOME-WIDE META-ANALYSIS OF DEPRESSION
David Mark Howard, M. Adams, T. Clarke, J. Hafferty +9 more
2019European Neuropsychopharmacology61 citations
Semantic Scholar
Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank
K. Glanville, Jonathan R. I. Coleman, David Mark Howard, Oliver Pain +7 more
2020BJPsych Open59 citations Open access
Semantic Scholar
Impact of Polygenic Risk for Schizophrenia on Cortical Structure in UK Biobank.
E. Neilson, Xue-Yi Shen, S. Cox, T. Clarke +10 more
2019Biological Psychiatry57 citations Open access
Semantic Scholar
Precision rehabilitation for aphasia by patient age, sex, aphasia severity, and time since stroke? A prespecified, systematic review-based, individual participant data, network, subgroup meta-analysis
M. Brady, Myzoon Ali, Kathryn VandenBerg, Linda J. Williams +64 more
2022International Journal of Stroke53 citations Open access
Semantic Scholar
Clinical Outcomes, Kadish-INSICA Staging and Therapeutic Targeting of SSTR2 in Olfactory Neuroblastoma
M. Lechner, Yoko Takahashi, M. Turri-Zanoni, Jacklyn Liu +97 more
2021European Journal of Cancer51 citations Open access
Semantic Scholar
Somatostatin receptor 2 expression in nasopharyngeal cancer is induced by Epstein Barr virus infection: impact on prognosis, imaging and therapy
M. Lechner, V. Schartinger, C. Steele, W. Nei +68 more
2021Nature Communications49 citations Open access
Semantic Scholar
Effects of depression on employment and social outcomes: a Mendelian randomisation study
Desmond D. Campbell, M. Green, N. Davies, E. Demou +7 more
2022Journal of Epidemiology and Community Health46 citations Open access
Semantic Scholar
Genome-wide meta-analysis of depression in 807,553 individuals identifies 102 independent variants with replication in a further 1,507,153 individuals
David Mark Howard, M. Adams, T. Clarke, J. Hafferty +34 more
2018bioRxiv41 citations Open access
Semantic Scholar
Genetic stratification of depression by neuroticism: revisiting a diagnostic tradition
M. Adams, David Mark Howard, M. Luciano, T. Clarke +6 more
2019Psychological Medicine40 citations Open access
Semantic Scholar
Quantifying Between-Cohort and Between-Sex Genetic Heterogeneity in Major Depressive Disorder
M. Trzaskowski, D. Mehta, W. Peyrot, D. Hawkes +22 more
2019American Journal of Medical Genetics Part B: Neuropsychiatric Genetics37 citations Open access
Semantic Scholar
Efficacy of spoken word comprehension therapy in patients with chronic aphasia: A cross-over randomised controlled trial with structural imaging
Victoria Fleming, Sonia L. E. Brownsett, A. Krason, María A. Maegli +11 more
2020Journal of Neurology Neurosurgery & Psychiatry34 citations Open access
Semantic Scholar
Genetics of self-reported risk-taking behaviour, trans-ethnic consistency and relevance to brain gene expression
R. Strawbridge, Joey Ward, Laura M. Lyall, E. Tunbridge +17 more
2018Translational Psychiatry34 citations Open access
Semantic Scholar
International Multicenter Study of Clinical Outcomes of Sinonasal Melanoma Shows Survival Benefit for Patients Treated with Immune Checkpoint Inhibitors and Potential Improvements to the Current TNM Staging System
M. Lechner, Yoko Takahashi, M. Turri-Zanoni, Marco Ferrari +65 more
2022Skull Base32 citations Open access
Semantic Scholar
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression
K. Glanville, J. Coleman, K. Hanscombe, J. Euesden +202 more
2020Biological Psychiatry32 citations Open access
Semantic Scholar
The role of neuroticism in self-harm and suicidal ideation: results from two UK population-based cohorts
J. Hafferty, L. Navrady, M. Adams, David Mark Howard +7 more
2019Social Psychiatry and Psychiatric Epidemiology31 citations Open access
Semantic Scholar
Addendum: Genome-wide association study of depression phenotypes in UK Biobank identifies variants in excitatory synaptic pathways
David Mark Howard, M. Adams, M. Shirali, T. Clarke +17 more
2018Nature Communications31 citations Open access
Semantic Scholar
Local CpG density affects the trajectory and variance of age-associated DNA methylation changes
Jonathan Higham, Lyndsay Kerr, Qian Zhang, R. Walker +13 more
2022Genome Biology29 citations Open access
Semantic Scholar
Genetic and environmental contributions to psychological resilience and coping
Lauren B Navrady, Yan-Ni Zeng, T. Clarke, M. Adams +3 more
2018Wellcome Open Research28 citations Open access
Semantic Scholar
Genetic stratification of depression in UK Biobank
David Mark Howard, L. Folkersen, J. Coleman, M. Adams +12 more
2020Translational Psychiatry27 citations Open access
Semantic Scholar
Genetic and environmental determinants of stressful life events and their overlap with depression and neuroticism
T. Clarke, Yanni Zeng, Lauren B Navrady, Charley Xia +16 more
201926 citations
Semantic Scholar
Clarifying the causes of consistent and inconsistent findings in genetics
Saloni Dattani, David Mark Howard, C. Lewis, P. Sham
2022Genetic Epidemiology22 citations Open access
Semantic Scholar
Methylome-wide association study of antidepressant use in Generation Scotland and the Netherlands Twin Register implicates the innate immune system
M. Barbu, F. Huider, A. Campbell, C. Amador +13 more
2021Molecular Psychiatry21 citations Open access
Semantic Scholar
Complex speech-language therapy interventions for stroke-related aphasia: the RELEASE study incorporating a systematic review and individual participant data network meta-analysis
M. Brady, Myzoon Ali, Kathryn VandenBerg, L. Williams +64 more
2022Health and Social Care Delivery Research20 citations Open access
Semantic Scholar
Pharmaco-epidemiology of antidepressant exposure in a UK cohort record-linkage study
J. Hafferty, E. Wigmore, David Mark Howard, M. Adams +7 more
2019Journal of Psychopharmacology20 citations Open access
Semantic Scholar
Accelerated Epigenetic Ageing in Major Depressive Disorder
H. Whalley, J. Gibson, R. Marioni, R. Walker +9 more
2017bioRxiv19 citations Open access
Semantic Scholar
SSTR2 in Nasopharyngeal Carcinoma: Relationship with Latent EBV Infection and Potential as a Therapeutic Target
Oscar Emanuel, Jacklyn Liu, V. Schartinger, W. Nei +17 more
2021Cancers17 citations Open access
Semantic Scholar
Epigenetic clocks predict prevalence and incidence of leading causes of death and disease burden
R. Hillary, A. Stevenson, D. McCartney, A. Campbell +10 more
2020bioRxiv17 citations Open access
Semantic Scholar
Polygenic scores for schizophrenia and major depression are associated with psychosocial risk factors in children: evidence of gene–environment correlation
Sandra Machlitt-Northen, R. Keers, P. Munroe, David Mark Howard +2 more
2022Journal of Child Psychology and Psychiatry and Allied Disciplines16 citations Open access
Semantic Scholar
Genome-wide association study of depression phenotypes in UK Biobank (n = 322,580) identifies the enrichment of variants in excitatory synaptic pathways
David Mark Howard, M. Adams, M. Shirali, T. Clarke +16 more
2017bioRxiv15 citations Open access
Semantic Scholar
Reading comprehension in aphasia: the relationship between linguistic performance, personal perspective, and preferences
J. Webster, Julie Morris, David Mark Howard
2022Aphasiology14 citations Open access
Semantic Scholar
Using Major Depression Polygenic Risk Scores to Explore the Depressive Symptom Continuum
B. Jermy, S. Hagenaars, K. Glanville, J. Coleman +4 more
2020bioRxiv14 citations Open access
Semantic Scholar
The effects of polygenic risk for psychiatric disorders and smoking behaviour on psychotic experiences in UK Biobank
Judit García-González, J. Ramírez, David Mark Howard, C. Brennan +2 more
2019Translational Psychiatry13 citations Open access
Semantic Scholar
Selective advantage of implementing optimal contributions selection and timescales for the convergence of long-term genetic contributions
David Mark Howard, R. Pong-Wong, P. Knap, V. Kremer +1 more
2018Genetics Selection Evolution13 citations Open access
Semantic Scholar
Polygenic risk scores for schizophrenia and major depression are associated with socio-economic indicators of adversity in two British community samples
Sandra Machlitt-Northen, R. Keers, P. Munroe, David Mark Howard +1 more
2022Translational Psychiatry10 citations Open access
Semantic Scholar
Utilising a systematic review-based approach to create a database of individual participant data for meta- and network meta-analyses: the RELEASE database of aphasia after stroke
Louise R. Williams, Myzoon Ali, Kathryn VandenBerg, L. Williams +64 more
2021Aphasiology10 citations Open access
Semantic Scholar
Methylome-wide association study of early life stressors and adult mental health
David Mark Howard, Oliver Pain, Ryan Arathimos, M. Barbu +14 more
2021medRxiv10 citations Open access
Semantic Scholar

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H. Whalley — researcher profile on SciRah