P. Singhal

Most-cited papers

Acute kidney injury in patients hospitalized with COVID-19
J. Hirsch, J. H. Ng, Daniel W. Ross, Purva D. Sharma +31 more
2020Kidney International1,294 citations Open access
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Outcomes of patients with end-stage kidney disease hospitalized with COVID-19
J. H. Ng, J. Hirsch, R. Wanchoo, Mala Sachdeva +31 more
2020Kidney International261 citations Open access
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APOL1 risk variants enhance podocyte necrosis through compromising lysosomal membrane permeability.
Xi-Qian Lan, A. Jhaveri, K. Cheng, Hongxiu Wen +7 more
2014AJP - Renal Physiology180 citations Open access
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Mutations in the gene that encodes the F-actin binding protein anillin cause FSGS.
R. Gbadegesin, G. Hall, A. Adeyemo, Nils Hanke +23 more
2014Journal of the American Society of Nephrology159 citations Open access
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High glucose induces autophagy in podocytes
Te’an Ma, Ji-Li Zhu, Xing-Hua Chen, Dong-Qing Zha +2 more
2013Experimental Cell Research116 citations Open access
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ANG II promotes autophagy in podocytes.
A. Yadav, Sridevi Vallabu, S. Arora, Pranay Tandon +3 more
2010American Journal of Physiology - Cell Physiology112 citations Open access
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Transplantation of Bone Marrow-derived MSCs Improves Cisplatinum-induced Renal Injury through Paracrine Mechanisms
K. Cheng, Partab Rai, A. Plagov, Xi-Qian Lan +8 more
2013Experimental and molecular pathology (Print)95 citations Open access
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Magnesium protects against cisplatin-induced acute kidney injury by regulating platinum accumulation.
M. Solanki, P. Chatterjee, Madhu Gupta, X. Xue +5 more
2014AJP - Renal Physiology72 citations Open access
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Activation of Notch signaling pathway in HIV-associated nephropathy
Madhulika Sharma, Shannon E. Callen, Da Zhang, P. Singhal +2 more
2010AIDS (London)69 citations Open access
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HIV Promotes NLRP3 Inflammasome Complex Activation in Murine HIV-Associated Nephropathy.
S. Haque, Xi-Qian Lan, Hongxiu Wen, Rivka Lederman +10 more
2016American Journal of Pathology65 citations Open access
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Nicotine Induces Podocyte Apoptosis through Increasing Oxidative Stress
Xi-Qian Lan, Rivka Lederman, Judith M. Eng, Seyedeh Shadafarin Marashi Shoshtari +3 more
2016PLoS ONE60 citations Open access
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APOL1 risk variants cause podocytes injury through enhancing endoplasmic reticulum stress
Hongxiu Wen, Vinod Kumar, Xi-Qian Lan, Seyedeh Shadafarin Marashi Shoshtari +10 more
2018Bioscience Reports59 citations Open access
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Angiotensin II induces nephrin dephosphorylation and podocyte injury: Role of caveolin-1
Zhi-Long Ren, W. Liang, Cheng Chen, Hong-Xia Yang +2 more
2011Cellular Signalling59 citations Open access
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Exon 4-encoded sequence is a major determinant of cytotoxicity of apolipoprotein L1.
Atanu K. Khatua, A. M. Cheatham, Etty Kruzel, P. Singhal +2 more
2015American Journal of Physiology - Cell Physiology56 citations Open access
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Aldosterone Induces Apoptosis in Rat Podocytes: Role of PI3-K/Akt and p38MAPK Signaling Pathways
Cheng Chen, W. Liang, Jun-Ya Jia, H. van Goor +2 more
2009Nephron Experimental Nephrology54 citations Open access
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Inhibition of p66ShcA Longevity Gene Rescues Podocytes from HIV-1-induced Oxidative Stress and Apoptosis*
Mohammad Husain, L. Meggs, H. Vashistha, S. Simoes +12 more
2009Journal of Biological Chemistry48 citations Open access
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Vitamin D Receptor Deficit Induces Activation of Renin Angiotensin System Via SIRT1 Modulation in Podocytes
N. Chandel, Kamesh Ayasolla, Hongxiu Wen, Xi-Qian Lan +4 more
2017Experimental and molecular pathology (Print)43 citations Open access
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Impact of APOL1 polymorphism and IL-1β priming in the entry and persistence of HIV-1 in human podocytes
Joanna Mikulak, F. Oriolo, F. Portale, P. Tentorio +5 more
2016Retrovirology43 citations Open access
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Morphine Induces Albuminuria by Compromising Podocyte Integrity
Xi-Qian Lan, Partab Rai, N. Chandel, K. Cheng +8 more
2013PLoS ONE41 citations Open access
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Full-length soluble urokinase plasminogen activator receptor down-modulates nephrin expression in podocytes
M. Alfano, P. Cinque, G. Giusti, S. Proietti +11 more
2015Scientific Reports40 citations Open access
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Protein domains of APOL1 and Its Risk Variants
Xi-Qian Lan, Hongxiu Wen, Rivka Lederman, A. Malhotra +4 more
2015Experimental and molecular pathology (Print)39 citations Open access
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sPLA2 IB induces human podocyte apoptosis via the M-type phospholipase A2 receptor
Yangbin Pan, Jian-Xin Wan, Yi-Peng Liu, Qian Yang +4 more
2014Scientific Reports38 citations Open access
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HIV-associated nephropathy: role of mammalian target of rapamycin pathway.
Dileep Kumar, Sridevi Konkimalla, A. Yadav, K. Sataranatarajan +3 more
2010American Journal of Pathology38 citations Open access
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HIVAN phenotype: consequence of epithelial mesenchymal transdifferentiation.
A. Yadav, Sridevi Vallabu, Dileep Kumar, G. Ding +3 more
2010AJP - Renal Physiology37 citations Open access
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HIV-1 and Kidney Cells: Better Understanding of Viral Interaction
Joanna Mikulak, P. Singhal
2010Nephron Experimental Nephrology34 citations Open access
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IQGAP1 regulates actin cytoskeleton organization in podocytes through interaction with nephrin
Yi-Peng Liu, W. Liang, Yingjie Yang, Yangbin Pan +4 more
2015Cellular Signalling33 citations Open access
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APOL1 and Kidney Cell Function.
Vinod Kumar, P. Singhal
2019AJP - Renal Physiology32 citations Open access
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Vascular Smooth Muscle Cells Contribute to APOL1-induced Podocyte Injury in HIV milieu
Xi-Qian Lan, Hongxiu Wen, M. Saleem, Joanna Mikulak +3 more
2015Experimental and molecular pathology (Print)31 citations Open access
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HIV compromises integrity of the podocyte actin cytoskeleton through downregulation of the vitamin D receptor.
N. Chandel, Bipin Sharma, Mohammad Husain, D. Salhan +6 more
2013AJP - Renal Physiology31 citations Open access
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HIV-induced kidney cell injury: role of ROS-induced downregulated vitamin D receptor.
D. Salhan, Mohammad Husain, Ashaan Subrati, Rohan Goyal +4 more
2012AJP - Renal Physiology31 citations Open access
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EDA2R Mediates Podocyte Injury in High Glucose Milieu
Xi-Qian Lan, Vinod Kumar, A. Jha, Rukhsana Aslam +8 more
2020Biochimie30 citations Open access
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Disruption of APOL1-miR193a Axis Induces Disorganization of Podocyte Actin Cytoskeleton
Vinod Kumar, N. Paliwal, K. Ayasolla, H. Vashistha +8 more
2019Scientific Reports30 citations Open access
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Angiotensin II down-regulates nephrin–Akt signaling and induces podocyte injury: roleof c-Abl
Qian Yang, Yi-Qiong Ma, Yi-Peng Liu, W. Liang +5 more
2016Molecular Biology of the Cell29 citations Open access
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Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy.
Madhulika Sharma, Lynn Magenheimer, Trisha Home, Karen N Tamano +5 more
2013AJP - Renal Physiology29 citations Open access
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Role of Apolipoprotein L1 in Human Parietal Epithelial Cell Transition.
Vinod Kumar, H. Vashistha, Xi-Qian Lan, N. Chandel +13 more
2018American Journal of Pathology28 citations Open access
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Nef interaction with actin compromises human podocyte actin cytoskeletal integrity
R. Tan, H. Patni, P. Tandon, Liming Luan +8 more
2012Experimental and molecular pathology (Print)28 citations Open access
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HIV-1 harboring renal tubular epithelial cell interaction with T cells results in T cell trans-infection.
Joanna Mikulak, S. Teichberg, T. Faust, H. Schmidtmayerova +1 more
2009Virology26 citations Open access
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Alterations in Plasma Membrane Ion Channel Structures Stimulate NLRP3 Inflammasomes Activation in APOL1 Risk Milieu
A. Jha, Vinod Kumar, S. Haque, K. Ayasolla +6 more
2019The FEBS Journal25 citations Open access
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Modulation of apolipoprotein L1-microRNA-193a axis prevents podocyte dedifferentiation in high-glucose milieu
Abheepsa Mishra, K. Ayasolla, Vinod Kumar, Xi-Qian Lan +12 more
201825 citations
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Hedgehog pathway plays a vital role in HIV-induced epithelial-mesenchymal transition of podocyte
Xi-Qian Lan, Hongxiu Wen, K. Cheng, A. Plagov +3 more
2017Experimental Cell Research25 citations Open access
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Epigenetic Modulation of Human Podocyte Vitamin D Receptor in HIV milieu
N. Chandel, Kameshwar Ayasolla, Xi-Qian Lan, Maria Sultana-Syed +7 more
2015Journal of Molecular Biology25 citations Open access
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IQGAP1 Mediates Angiotensin II-Induced Apoptosis of Podocytes via the ERK1/2 MAPK Signaling Pathway
Yi-Peng Liu, W. Liang, Qian Yang, Zhi-Long Ren +4 more
2013American Journal of Nephrology25 citations
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Hyperglycemia Enhances Kidney Cell Injury in HIVAN through down regulation of vitamin D receptors
Partab Rai, Tejinder Singh, Rivka Lederman, Amrita Chawla +7 more
2014Cellular Signalling23 citations Open access
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HIV-1 entry into human podocytes is mediated through lipid rafts.
Joanna Mikulak, P. Singhal
2010Kidney International23 citations Open access
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Heme Oxygenase-1 Modulates Mesangial Cell Proliferation by p21waf1 Upregulation
Dileep Kumar, M. Bhaskaran, L. Alagappan, Dipti Tori +4 more
2010Renal Failure23 citations Open access
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Polymorphisms in the surfactant protein a gene are associated with the susceptibility to recurrent urinary tract infection in chinese women.
Jiao Liu, Feng-Qi Hu, W. Liang, Gui-Rong Wang +2 more
2010Tohoku journal of experimental medicine22 citations Open access
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APOL1 risk variants and the development of HIV Associated Nephropathy
Rohan Goyal, P. Singhal
2020The FEBS Journal21 citations Open access
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mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN.
Partab Rai, A. Plagov, Xi-Qian Lan, N. Chandel +9 more
2013AJP - Renal Physiology21 citations Open access
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Tubular Cell HIV-Entry through Apoptosed CD4 T cells: A Novel Pathway
Priyanka Singh, Hersh V. Goel, Mohammad Husain, Xi-Qian Lan +5 more
2012Virology21 citations Open access
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Disrupted APOL1-miR193a Axis Dedifferentiates Podocytes through Autophagy Blockade in APOL1 Risk Milieu.
Vinod Kumar, K. Ayasolla, A. Jha, Abheepsa Mishra +10 more
2019American Journal of Physiology - Cell Physiology20 citations Open access
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