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Kong-Zhen Hu · SciRah

Researcher profile · Semantic Scholar

Kong-Zhen Hu

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Kong-Zhen Hu — researcher profile on SciRah

h-index: 20
Works: 92
Citations: 1,346

Most-cited papers

Comparison of 68Ga-FAPI and 18F-FDG PET/CT in the Evaluation of Advanced Lung Cancer.
Li-Juan Wang, Gang-Hua Tang, Kong-Zhen Hu, Xinran Liu +7 more
2022Radiology150 citations
Semantic Scholar
[18F]FAPI-42 PET imaging in cancer patients: optimal acquisition time, biodistribution, and comparison with [68Ga]Ga-FAPI-04
Kong-Zhen Hu, Li-Juan Wang, Hu-Bing Wu, Shun Huang +5 more
2021European Journal of Nuclear Medicine and Molecular Imaging107 citations
Semantic Scholar
Comprehensive Analysis of Fibroblast Activation Protein Expression in Interstitial Lung Diseases
Peng-Hui Yang, Qi Fang, Z. Fu, Jia Li +17 more
2022American Journal of Respiratory and Critical Care Medicine101 citations Open access
Semantic Scholar
Preclinical evaluation and pilot clinical study of [18F]AlF-labeled FAPI-tracer for PET imaging of cancer associated fibroblasts
Kong-Zhen Hu, Jun-Qi Li, Li-Juan Wang, Yong Huang +7 more
2021Acta Pharmaceutica Sinica B93 citations Open access
Semantic Scholar
Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer
Jiao Wang, Qiong Huang, Xingbin Hu, Shuyi Zhang +13 more
2022Cancer Research86 citations Open access
Semantic Scholar
18F- or 177Lu-labeled bivalent ligand of fibroblast activation protein with high tumor uptake and retention
Ho Cheung William Li, Shimin Ye, Li Li, Jiawei Zhong +4 more
2022European Journal of Nuclear Medicine and Molecular Imaging62 citations
Semantic Scholar
In Vivo Cancer Dual-Targeting and Dual-Modality Imaging with Functionalized Quantum Dots
Kong-Zhen Hu, Hong-Liang Wang, Gang-Hua Tang, Ting-Ting Huang +4 more
2015Journal of Nuclear Medicine41 citations Open access
Semantic Scholar
SAR Studies on Truxillic Acid Mono Esters as a New Class of Antinociceptive Agents Targeting Fatty Acid Binding Proteins
Su Yan, M. Elmes, Simon Tong, Kong-Zhen Hu +23 more
2018European journal of medicinal chemistry40 citations Open access
Semantic Scholar
Radiosynthesis and Preclinical Evaluation of Bispecific PSMA/FAP Heterodimers for Tumor Imaging
Kong-Zhen Hu, Li Li, Yong Huang, Shimin Ye +6 more
2022Pharmaceuticals37 citations Open access
Semantic Scholar
Noninvasive imaging of FAP expression using positron emission tomography: A comparative evaluation of a [18F]-labeled glycopeptide-containing FAPI with [18F]FAPI-42
Jia-Wen Huang, Lilan Fu, Xiao-Jun Zhang, Shun Huang +7 more
2023European Journal of Nuclear Medicine and Molecular Imaging35 citations
Semantic Scholar
Radiofluorinated GPC3-Binding Peptides for PET Imaging of Hepatocellular Carcinoma
Youcai Li, Jun Zhang, Jiamei Gu, Kong-Zhen Hu +4 more
2019Molecular Imaging and Biology32 citations Open access
Semantic Scholar
Synthesis and preclinical evaluation of an Al18F radiofluorinated bivalent PSMA ligand.
Yong Huang, Hong-Sheng Li, Shiming Ye, Gang-Hua Tang +2 more
2021European journal of medicinal chemistry28 citations
Semantic Scholar
Positron emission tomography imaging of cell death with [18F]FPDuramycin
Shao-Bo Yao, Kong-Zhen Hu, Gang-Hua Tang, Xiang Liang +4 more
2014Apoptosis28 citations
Semantic Scholar
Synthesis and biological evaluation of N-(2-[(18)F]Fluoropropionyl)-L-methionine for tumor imaging.
Kong-Zhen Hu, Hong-Liang Wang, Ting-Ting Huang, Gang-Hua Tang +3 more
2013Nuclear Medicine and Biology27 citations
Semantic Scholar
Radiosynthesis and biological evaluation of 18F-labeled 4-anilinoquinazoline derivative (18F-FEA-Erlotinib) as a potential EGFR PET agent.
Shun Huang, Yan-Jiang Han, Min Chen, Kong-Zhen Hu +10 more
2017Bioorganic & Medicinal Chemistry Letters24 citations
Semantic Scholar
Noninvasive positron emission tomography imaging of cell death using a novel small-molecule probe, 18F labeled bis(zinc(II)-dipicolylamine) complex
Hong-Liang Wang, Xiao-Lan Tang, Gang-Hua Tang, Ting-Ting Huang +6 more
2013Apoptosis24 citations
Semantic Scholar
Automatic Production and Preliminary PET Imaging of a New Imaging Agent [18F]AlF-FAPT
Jia-Wen Huang, Lilan Fu, Kong-Zhen Hu, Shun Huang +5 more
2022Frontiers in Oncology23 citations Open access
Semantic Scholar
Development of [18F]Maleimide-Based Glycogen Synthase Kinase-3β Ligands for Positron Emission Tomography Imaging.
Kong-Zhen Hu, D. Patnaik, T. Collier, Katarzyna N Lee +11 more
2017ACS Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Radiosynthesis and Biological Evaluation of N-[18F]Labeled Glutamic Acid as a Tumor Metabolic Imaging Tracer
Kong-Zhen Hu, Kan Du, Gang-Hua Tang, Shao-Bo Yao +5 more
2014PLoS ONE22 citations Open access
Semantic Scholar
Synthesis and biological evaluation of Al[18F]-NOTA-IPB-PDL1P as a molecular probe for PET imaging of PD-L1 positive tumors.
Peng-Hui Sun, Yan-Jiang Han, Kong-Zhen Hu, Shun Huang +5 more
2022Bioorganic chemistry (Print)21 citations
Semantic Scholar
Synthesis and preclinical evaluation of novel 18F-labeled fibroblast activation protein tracers for positron emission tomography imaging of cancer-associated fibroblasts.
Hui Zhou, Jiawei Zhong, Si-Min Peng, Yang Liu +5 more
2023European journal of medicinal chemistry18 citations
Semantic Scholar
Synthesis and evaluation of [18F]FP-Lys-GE11 as a new radiolabeled peptide probe for epidermal growth factor receptor (EGFR) imaging.
Xueli Li, Kong-Zhen Hu, Wenfeng Liu, Yuan-Feng Wei +8 more
2020Nuclear Medicine and Biology15 citations
Semantic Scholar
Positron emission tomography imaging of cardiomyocyte apoptosis with a novel molecule probe [18F]FP-DPAZn2
Ting Sun, Gang-Hua Tang, Hua Tian, Kong-Zhen Hu +3 more
2015OncoTarget15 citations Open access
Semantic Scholar
Radiosynthesis and biological evaluation of 5-(3-[18F]fluoropropyloxy)-L-tryptophan for tumor PET imaging.
Shan-Zhen He, Gang-Hua Tang, Kong-Zhen Hu, Hong-Liang Wang +4 more
2013Nuclear Medicine and Biology15 citations
Semantic Scholar
Synthesis and preclinical evaluation of a heterodimeric radioligand targeting fibroblast activation protein and integrin-αvβ3.
Qingsong Yan, Jiawei Zhong, Y. Liu, Simin Peng +3 more
2023European journal of medicinal chemistry14 citations
Semantic Scholar
Radiosynthesis and biological evaluation of an fluorine-18 labeled galactose derivative [18F]FPGal for imaging the hepatic asialoglycoprotein receptor.
Peng-Hui Sun, Yun Zhu, Yan-Jiang Han, Kong-Zhen Hu +4 more
2020Bioorganic & Medicinal Chemistry Letters13 citations
Semantic Scholar
Synthesis and Evaluation of 18F-Labeled Peptide for Gonadotropin-Releasing Hormone Receptor Imaging
Shun Huang, Hong-Sheng Li, Yan-Jiang Han, Lilan Fu +8 more
2019Contrast Media & Molecular Imaging13 citations Open access
Semantic Scholar
Synthesis and preliminary biological evaluation of S-11C-methyl-d-cysteine as a new amino acid PET tracer for cancer imaging
Ting-Ting Huang, Gang-Hua Tang, Hong-Liang Wang, Da-Hong Nie +6 more
2014Amino Acids13 citations
Semantic Scholar
[18F]AlF-ND-bisFAPI PET imaging of fibroblast activation protein as a biomarker to monitor the progression of liver fibrosis
Ho Cheung William Li, Ruoxue Dai, Yueqi Huang, Jiawei Zhong +4 more
2024Hepatology Communications12 citations Open access
Semantic Scholar
Radiosynthesis, preclinical evaluation and pilot clinical PET imaging study of a 18F-labeled tracer targeting fibroblast activation protein.
Lilan Fu, Jia-Wen Huang, Qingxing Liu, Fei Xie +6 more
2023Bioorganic chemistry (Print)12 citations
Semantic Scholar
[68Ga]Ga-FAPI-04 PET/CT imaging in signet-ring cell carcinoma of sigmoid colon
Lilan Fu, Kong-Zhen Hu, Gang-Hua Tang, Hu-Bing Wu +1 more
2021European Journal of Nuclear Medicine and Molecular Imaging12 citations
Semantic Scholar
Automated radiosynthesis and preclinical evaluation of Al[18F]F-NOTA-P-GnRH for PET imaging of GnRH receptor-positive tumors.
Shun Huang, Hu-Bing Wu, Bao-Yuan Li, Lilan Fu +3 more
2020Nuclear Medicine and Biology12 citations
Semantic Scholar
A novel tree shrew model of lipopolysaccharide-induced acute respiratory distress syndrome
Jun He, Yue Zhao, Z. Fu, Li Chen +14 more
2023Journal of Advanced Research11 citations Open access
Semantic Scholar
Formulation and Preclinical Testing of Tc-99m-Labeled HYNIC-Glc-FAPT as a FAP-Targeting Tumor Radiotracer.
Xiaoqiang Yang, Gui-Ping Li, Chuyin Ruan, Kong-Zhen Hu +1 more
2023Bioconjugate chemistry11 citations
Semantic Scholar
Synthesis and evaluation of a radiolabeled bis-zinc(II)–cyclen complex as a potential probe for in vivo imaging of cell death
Hong-Liang Wang, Zhi-Fang Wu, Si-Jin Li, Kong-Zhen Hu +1 more
2017Apoptosis11 citations
Semantic Scholar
Comparison of three 18F-labeled carboxylic acids with 18F-FDG of the differentiation tumor from inflammation in model mice
Hong-Liang Wang, Gang-Hua Tang, Kong-Zhen Hu, Ting-Ting Huang +3 more
2016BMC Medical Imaging11 citations Open access
Semantic Scholar
Development of ibuprofen-modified fibroblast activation protein radioligands to improve cancer therapy.
Hui Zhou, Jiawei Zhong, Yang Liu, Si-Min Peng +4 more
2024European journal of medicinal chemistry10 citations
Semantic Scholar
Novel 18F-Labeled Isonicotinamide-Based Radioligands for Positron Emission Tomography Imaging of Glycogen Synthase Kinase-3β.
Yu-Hua Zhong, Shaoxi Yang, Jianyuan Cui, Jie-lin Wang +9 more
2021Molecular Pharmaceutics10 citations
Semantic Scholar
18F-FP-PEG2-β-Glu-RGD2: A Symmetric Integrin αvβ3-Targeting Radiotracer for Tumor PET Imaging
Kong-Zhen Hu, Xiao-Lan Tang, Gang-Hua Tang, Shao-Bo Yao +6 more
2015PLoS ONE10 citations Open access
Semantic Scholar
Automated synthesis of symmetric integrin αvβ3-targeted radiotracer [18F]FP-PEG3-β-Glu-RGD2
Kong-Zhen Hu, Hong-Liang Wang, Gang-Hua Tang, Ting-Ting Huang +3 more
2013Journal of Radioanalytical and Nuclear Chemistry9 citations
Semantic Scholar
Synthesis and preclinical evaluation of a novel PET/fluorescence dual-modality probe targeting fibroblast activation protein.
Xiao-Jun Zhang, Jia-Wen Huang, Fengping Gong, Zhikai Cai +3 more
2024Bioorganic chemistry (Print)8 citations
Semantic Scholar
177Lu-Labeled Bivalent Ligands of Prostate-Specific Membrane Antigen for Endoradiotherapy of Prostate Cancer.
Ruoxue Dai, Zhikai Cai, R. Hu, Yueqi Huang +4 more
2023Molecular Pharmaceutics8 citations
Semantic Scholar
Molecular PET Imaging of Cyclophosphamide Induced Apoptosis with 18F-ML-8
Shao-Bo Yao, Kong-Zhen Hu, Gang-Hua Tang, Siyuan Gao +5 more
2015BioMed Research International8 citations Open access
Semantic Scholar
Development of Cysteic Acid-Modified FAP Radioligands for Enhanced Renal Clearance: From Preclinical Optimization to First-in-Human Study.
Si-Min Peng, Bao-Yuan Li, Ming-Ming Sun, Jia-qi Yang +7 more
2025Journal of Medicinal Chemistry7 citations
Semantic Scholar
Synthesis and Preclinical Evaluation of the Fibrin-Binding Cyclic Peptide 18F-iCREKA: Comparison with Its Contrasted Linear Peptide
Yin Zhang, Li-Juan Wang, Si-rui Yu, Kong-Zhen Hu +5 more
2019Contrast Media & Molecular Imaging7 citations Open access
Semantic Scholar
Radiosynthesis and biological evaluation of fluorine-18 labeled N-acetylgalactosamine derivative [18F]FPGalNAc for PET imaging of asialoglycoprotein receptor-positive tumors.
Peng-Hui Sun, Yan-Jiang Han, Yun Zhu, Kong-Zhen Hu +5 more
2020Nuclear Medicine and Biology6 citations
Semantic Scholar
Semi-automated radiosynthesis of 18F-labeled l-arginine derivative as a potential PET tracer for lung cancer imaging
Siyuan Gao, Gang-Hua Tang, Shuguang Zhu, Kong-Zhen Hu +13 more
2016Journal of Radioanalytical and Nuclear Chemistry6 citations
Semantic Scholar
Cerebral [18F]AIF-FAPI-42-Based PET Imaging of Fibroblast Activation Protein for Non-invasive Quantification of Fibrosis After Ischemic Stroke
Pei-Pei Tang, Yang Liu, Si-Min Peng, Zhikai Cai +4 more
2024Translational Stroke Research5 citations
Semantic Scholar
Radiosynthesis and biological evaluation of 18F-labeled bispecific heterodimer targeted dual gastrin-releasing peptide receptor and prostate-specific membrane antigen for prostate cancer imaging
Shimin Ye, Hong-Sheng Li, Kong-Zhen Hu, Li Li +3 more
2021Nuclear medicine communications5 citations
Semantic Scholar
Comparative uptake of ¹⁸F-FEN-DPAZn2, ¹⁸F-FECH, ¹⁸F-fluoride, and ¹⁸F-FDG in fibrosarcoma and aseptic inflammation.
Xiang Liang, Gang-Hua Tang, Hong-Liang Wang, Kong-Zhen Hu +4 more
2014Applied Radiation and Isotopes5 citations
Semantic Scholar

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Shun Huang×15
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Yan-Jiang Han×13
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Hu-Bing Wu×12
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Hong-Liang Wang

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Ting-Ting Huang×9

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Xiao-Lan Tang×8

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