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S. Sadhasivam · SciRah

Researcher profile · Semantic Scholar

S. Sadhasivam

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S. Sadhasivam — researcher profile on SciRah

h-index: 41
Works: 189
Citations: 5,710

Most-cited papers

Clinical Pharmacogenetics Implementation Consortium Guidelines for Cytochrome P450 2D6 Genotype and Codeine Therapy: 2014 Update
K. Crews, A. Gaedigk, H. M. Dunnenberger, J. Leeder +9 more
2014Clinical pharmacology and therapy630 citations Open access
Semantic Scholar
Clinical Pharmacogenetics Implementation Consortium (CPIC) Guideline for CYP2D6 Genotype and Use of Ondansetron and Tropisetron
G. Bell, K. Caudle, M. Whirl-Carrillo, R. Gordon +7 more
2017Clinical pharmacology and therapy196 citations Open access
Semantic Scholar
Predicting the pain continuum after adolescent idiopathic scoliosis surgery: A prospective cohort study
V. Chidambaran, L. Ding, D. L. Moore, K. Spruance +7 more
2017European Journal of Pain121 citations Open access
Semantic Scholar
Gender, genetics, and analgesia: understanding the differences in response to pain relief
Senthil Packiasabapathy, S. Sadhasivam
2018Journal of Pain Research78 citations Open access
Semantic Scholar
ABCC3 and OCT1 genotypes influence pharmacokinetics of morphine in children
Raja Venkatasubramanian, T. Fukuda, J. Niu, T. Mizuno +3 more
2014Pharmacogenomics (London)78 citations Open access
Semantic Scholar
DNA methylation at the mu-1 opioid receptor gene (OPRM1) promoter predicts preoperative, acute, and chronic postsurgical pain after spine fusion
V. Chidambaran, Xue Zhang, Lisa J. Martin, L. Ding +5 more
2017Pharmacogenomics and Personalized Medicine72 citations Open access
Semantic Scholar
Pupillometry in perioperative medicine: a narrative review
Senthil Packiasabapathy, Valluvan Rangasamy, S. Sadhasivam
2021Canadian Journal of Anesthesia/Journal canadien d'anesthésie61 citations Open access
Semantic Scholar
Codeine and Opioid Metabolism – Implications and Alternatives for Pediatric Pain Management
V. Chidambaran, S. Sadhasivam, M. Mahmoud
2017Current Opinion in Anaesthesiology60 citations Open access
Semantic Scholar
OCT1 genetic variants are associated with postoperative morphine-related adverse effects in children.
R. Balyan, Xue Zhang, V. Chidambaran, Lisa J. Martin +4 more
2017Pharmacogenomics (London)50 citations Open access
Semantic Scholar
Characterization of Contributing Factors to Variability in Morphine Clearance Through PBPK Modeling Implemented With OCT1 Transporter
C. Emoto, Tsuyoshi Fukuda, Trevor N. Johnson, S. Neuhoff +2 more
2016CPT: Pharmacometrics & Systems Pharmacology47 citations Open access
Semantic Scholar
Anesthesia‐ and opioids‐related malpractice claims following tonsillectomy in USA: LexisNexis claims database 1984–2012
R. Subramanyam, V. Chidambaran, L. Ding, C. Myer +1 more
2014Paediatric anaesthesia47 citations
Semantic Scholar
Large-scale genomic study reveals robust activation of the immune system following advanced Inner Engineering meditation retreat
Vijayendran Chandran, Mei-Ling Bermúdez, Mert Koka, B. Chandran +6 more
2021Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
Association of OPRM1 A118G variant with risk of morphine-induced respiratory depression following spine fusion in adolescents
V. Chidambaran, Jagroop Mavi, H. Esslinger, Valentina Pilipenko +3 more
2014The Pharmacogenomics Journal44 citations Open access
Semantic Scholar
Methadone-based Multimodal Analgesia Provides the Best-in-class Acute Surgical Pain Control and Functional Outcomes With Lower Opioid Use Following Major Posterior Fusion Surgery in Adolescents With Idiopathic Scoliosis
Jian Ye, Karen S. Myung, Senthil Packiasabapathy, Jeffrey S. Yu +5 more
2020Pediatric Quality & Safety43 citations Open access
Semantic Scholar
Pharmacogenomics of oxycodone: a narrative literature review.
Nelly N Umukoro, B. Aruldhas, Ryan Rossos, Dhanashri Pawale +2 more
2021Pharmacogenomics (London)42 citations Open access
Semantic Scholar
CYP2D6 pharmacogenetic and oxycodone pharmacokinetic association study in pediatric surgical patients.
R. Balyan, M. Mecoli, Raja Venkatasubramanian, V. Chidambaran +8 more
2017Pharmacogenomics (London)41 citations Open access
Semantic Scholar
Resting State Functional MRI in Infants with Prenatal Opioid Exposure – A Pilot Study
R. Radhakrishnan, Nahla M. H. Elsaid, S. Sadhasivam, Thomas Reher +4 more
2020Neuroradiology40 citations Open access
Semantic Scholar
Opioid-related adverse effects in children undergoing surgery: unequal burden on younger girls with higher doses of opioids.
S. Sadhasivam, V. Chidambaran, Vanessa A. Olbrecht, Andrew J. Costandi +4 more
2015Pain medicine (Malden, Mass.)40 citations Open access
Semantic Scholar
Inner Engineering Practices and Advanced 4-day Isha Yoga Retreat Are Associated with Cannabimimetic Effects with Increased Endocannabinoids and Short-Term and Sustained Improvement in Mental Health: A Prospective Observational Study of Meditators
S. Sadhasivam, Suresh Alankar, R. Maturi, Ramana V. Vishnubhotla +9 more
2020Evidence-Based Complementary and Alternative Medicine36 citations Open access
Semantic Scholar
A novel perioperative multi-dose methadone-based multi-modal analgesic strategy in children achieved safe and low analgesic blood methadone levels enabling opioid sparing sustained analgesia with minimal adverse effects
S. Sadhasivam, B. Aruldhas, Senthil Packiasabapathy, B. Overholser +5 more
2021Anesthesia and Analgesia34 citations Open access
Semantic Scholar
Intravenous acetaminophen reduces length of stay via mediation of postoperative opioid consumption following posterior spinal fusion in a pediatric cohort
Vanessa A. Olbrecht, L. Ding, K. Spruance, Monir Hossain +2 more
2017The Clinical Journal of Pain32 citations Open access
Semantic Scholar
Novel Associations between FAAH Genetic Variants and Postoperative Central Opioid related Adverse Effects
S. Sadhasivam, Xue Zhang, V. Chidambaran, Jagroop Mavi +6 more
2015The Pharmacogenomics Journal32 citations Open access
Semantic Scholar
Cost-effectiveness of intravenous acetaminophen and ketorolac in adolescents undergoing idiopathic scoliosis surgery
V. Chidambaran, R. Subramanyam, L. Ding, S. Sadhasivam +5 more
2018Paediatric anaesthesia31 citations Open access
Semantic Scholar
POPULATION PHARMACOKINETIC-PHARMACODYNAMIC MODELING AND DOSING SIMULATION OF PROPOFOL MAINTENANCE ANESTHESIA IN SEVERELY OBESE ADOLESCENTS
V. Chidambaran, Raja Venkatasubramanian, S. Sadhasivam, H. Esslinger +6 more
2015Paediatric anaesthesia31 citations Open access
Semantic Scholar
Global Brain Functional Network Connectivity in Infants With Prenatal Opioid Exposure
R. Radhakrishnan, Ramana V. Vishnubhotla, Yi Zhao, Jing-Wen Yan +5 more
2022Frontiers in Pediatrics29 citations Open access
Semantic Scholar
ABCC3 Genetic Variants are Associated with Postoperative Morphine-induced Respiratory Depression and Morphine Pharmacokinetics in Children
V. Chidambaran, Raja Venkatasubramanian, Xue Zhang, Lisa J. Martin +6 more
2016The Pharmacogenomics Journal27 citations Open access
Semantic Scholar
Advanced Meditation Alters Resting-State Brain Network Connectivity Correlating With Improved Mindfulness
Ramana V. Vishnubhotla, R. Radhakrishnan, Kestas Kveraga, R. Deardorff +6 more
2021Frontiers in Psychology26 citations Open access
Semantic Scholar
Genetics of perioperative pain management
Senthil Packiasabapathy, Nicole D. Horn, S. Sadhasivam
2018Current Opinion in Anaesthesiology25 citations Open access
Semantic Scholar
Isha Yoga Practices and Participation in Samyama Program are Associated with Reduced HbA1C and Systemic Inflammation, Improved Lipid Profile, and Short-Term and Sustained Improvement in Mental Health: A Prospective Observational Study of Meditators
S. Sadhasivam, Suresh Alankar, R. Maturi, Amy Williams +11 more
2021Frontiers in Psychology24 citations Open access
Semantic Scholar
Neuroimaging in Infants with Prenatal Opioid Exposure: Current Evidence, Recent Developments and Targets for Future Research
R. Radhakrishnan, G. G. Grecco, K. Stolze, Brady K. Atwood +4 more
2020Journal of neuroradiology = Journal de neuroradiologie23 citations Open access
Semantic Scholar
Pharmacogenomics of methadone: a narrative review of literature.
Senthil Packiasabapathy, B. Aruldhas, Nicole D. Horn, B. Overholser +3 more
2020Pharmacogenomics (London)23 citations Open access
Semantic Scholar
Propofol Pharmacokinetics and Estimation of Fetal Propofol Exposure during Mid-Gestational Fetal Surgery: A Maternal-Fetal Sheep Model
Pornswan Ngamprasertwong, M. Dong, J. Niu, Raja Venkatasubramanian +2 more
2016PLoS ONE21 citations Open access
Semantic Scholar
The effect of a one-time 15-minute guided meditation (Isha Kriya) on stress and mood disturbances among operating room professionals: a prospective interventional pilot study
Valluvan Rangasamy, Ammu Thampi Susheela, Ariel Mueller, T. Chang +2 more
2019F1000Research20 citations Open access
Semantic Scholar
Pilot Study of Fetal Brain Development and Morphometry in Prenatal Opioid Exposure and Smoking on Fetal MRI
R. Radhakrishnan, Brandon P. Brown, D. Haas, Yong Zang +2 more
2021Journal of neuroradiology = Journal de neuroradiologie19 citations Open access
Semantic Scholar
Intraoperative ketorolac for pediatric tonsillectomy: Effect on post-tonsillectomy hemorrhage and perioperative analgesia.
C. Rabbani, Zachary E. Pflum, M. Ye, John D. Gettelfinger +3 more
2020International Journal of Pediatric Otorhinolaryngology17 citations
Semantic Scholar
Thalamocortical functional connectivity in infants with prenatal opioid exposure correlates with severity of neonatal opioid withdrawal syndrome
R. Radhakrishnan, Ramana V. Vishnubhotla, Zoe Guckien, Yi Zhao +3 more
2022Neuroradiology16 citations
Semantic Scholar
Electronic Medical Records as a Replacement for Prospective Research Data Collection in Postoperative Pain and Opioid Response Studies
T. Lingren, S. Sadhasivam, Xue Zhang, Keith A. Marsolo
2017Int. J. Medical Informatics15 citations Open access
Semantic Scholar
Implementation of CYP2D6-guided opioid therapy at Cincinnati Children's Hospital Medical Center.
Laura B. Ramsey, C. Prows, V. Chidambaran, S. Sadhasivam +6 more
2023American Journal of Health-System Pharmacy14 citations Open access
Semantic Scholar
Brain structural connectome in neonates with prenatal opioid exposure
Ramana V. Vishnubhotla, Yi Zhao, Qiu-Ting Wen, Jonathan Dietrich +3 more
2022Frontiers in Neuroscience13 citations Open access
Semantic Scholar
Considerations for the Utility of the CPIC Guideline for CYP2D6 Genotype and Codeine Therapy.
K. Crews, K. Caudle, H. M. Dunnenberger, S. Sadhasivam +1 more
2015Clinical Chemistry13 citations
Semantic Scholar
Fatty acid amide hydrolase-morphine interaction influences ventilatory response to hypercapnia and postoperative opioid outcomes in children.
V. Chidambaran, Valentina Pilipenko, K. Spruance, Raja Venkatasubramanian +8 more
2017Pharmacogenomics (London)12 citations Open access
Semantic Scholar
Pharmacokinetic modeling of R and S‐Methadone and their metabolites to study the effects of various covariates in post‐operative children
B. Aruldhas, Sara K. Quinney, B. Overholser, M. Heathman +5 more
2021CPT: Pharmacometrics & Systems Pharmacology10 citations Open access
Semantic Scholar
Influence of MRP3 Genetics and Hepatic Expression Ontogeny for Morphine Disposition in Neonatal and Pediatric Patients
David Hahn, T. Fukuda, Joshua C. Euteneuer, T. Mizuno +3 more
2020Journal of clinical pharmacology10 citations
Semantic Scholar
Novel associations between CYP2B6 polymorphisms, perioperative methadone metabolism and clinical outcomes in children
Senthil Packiasabapathy, B. Aruldhas, Pengyue Zhang, B. Overholser +2 more
2021Pharmacogenomics (London)9 citations Open access
Semantic Scholar
Surgical site infection related to use of elastomeric pumps in pectus excavatum repair. Lessons learned from root cause analysis.
N. Apelt, J. Schaffzin, Christina Bates, Rebeccah L. Brown +3 more
2017Journal of Pediatric Surgery9 citations
Semantic Scholar
Role of Intraoperative Neuromonitoring to Predict Postoperative Delirium in Cardiovascular Surgery.
Abdullah M. Al-Qudah, Omar Al Ta'ani, P. Thirumala, Ibrahim Sultan +10 more
2023Journal of Cardiothoracic and Vascular Anesthesia8 citations
Semantic Scholar
Personalized pediatric anesthesia and pain management: problem-based review.
Senthil Packiasabapathy, Valluvan Rangasamy, Nicole D. Horn, M. Hendrickson +2 more
2020Pharmacogenomics (London)8 citations Open access
Semantic Scholar
Bayesian modeling to predict malignant hyperthermia susceptibility and pathogenicity of RYR1, CACNA1S and STAC3 variants.
S. Sadhasivam, B. Brandom, R. Henker, J. McAuliffe
2019Pharmacogenomics (London)8 citations Open access
Semantic Scholar
Role of the NeuroCuple™ Device for the Postoperative Pain Management of Patients Undergoing Unilateral Primary Total Knee and Hip Arthroplasty: A Pilot Prospective, Randomized, Open-Label Study
J. Chelly, Brian A. Klatt, Y. Groff, Michael J. O'Malley +2 more
2023Journal of Clinical Medicine7 citations Open access
Semantic Scholar
Opioid use disorder in pediatric populations: considerations for perioperative pain management and precision opioid analgesia
Yun-Han Chen, Anastasios Xenitidis, Paul Hoffmann, L. Matthews +7 more
2024Expert Review of Clinical Pharmacology6 citations
Semantic Scholar

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V. Chidambaran×16
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V. Chidambaran — researcher profile on SciRah
Senthil Packiasabapathy×10
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Senthil Packiasabapathy — researcher profile on SciRah
A. Vinks×9
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Ramana V. Vishnubhotla×7
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Janelle S Renschler

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R. Radhakrishnan×7

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Raja Venkatasubramanian×6

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T. Fukuda — researcher profile on SciRah

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T. Mizuno — researcher profile on SciRah

Lisa J. Martin×5

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Dhanashri Pawale×5

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B. Subramaniam×5

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