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N. F. Brown · SciRah

Researcher profile · Semantic Scholar

N. F. Brown

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N. F. Brown — researcher profile on SciRah

h-index: 30
Works: 37
Citations: 3,449

Most-cited papers

Genomic plasticity of the causative agent of melioidosis, Burkholderia pseudomallei.
M. Holden, R. Titball, S. Peacock, A. Cerdeño-Tárraga +44 more
2004Proceedings of the National Academy of Sciences of the United States of America820 citations Open access
Semantic Scholar
Identification and characterization of NleA, a non‐LEE‐encoded type III translocated virulence factor of enterohaemorrhagic Escherichia coli O157:H7
S. Gruenheid, I. Sekirov, N. Thomas, W. Deng +9 more
2004Molecular Microbiology233 citations
Semantic Scholar
Salmonella enterica serovar Typhimurium effectors SopB, SopE, SopE2 and SipA disrupt tight junction structure and function
Erin C. Boyle, N. F. Brown, B. B. Finlay
2006Cellular Microbiology207 citations Open access
Semantic Scholar
Expression and Secretion of Salmonella Pathogenicity Island-2 Virulence Genes in Response to Acidification Exhibit Differential Requirements of a Functional Type III Secretion Apparatus and SsaL*
B. Coombes, N. F. Brown, Y. Valdéz, J. Brumell +1 more
2004Journal of Biological Chemistry179 citations Open access
Semantic Scholar
A Type IV Pilin, PilA, Contributes to Adherence of Burkholderia pseudomallei and Virulence In Vivo
Angela E. Essex-Lopresti, J. Boddey, Richard Thomas, Martin P. Smith +8 more
2005Infection and Immunity137 citations Open access
Semantic Scholar
Salmonella Pathogenicity Island 2 Is Expressed Prior to Penetrating the Intestine
N. F. Brown, B. A. Vallance, B. Coombes, Y. Valdéz +2 more
2005PLoS Pathogens133 citations Open access
Semantic Scholar
SopD2 is a Novel Type III Secreted Effector of Salmonella typhimurium That Targets Late Endocytic Compartments Upon Delivery Into Host Cells
J. Brumell, Sonya L Kujat-Choy, N. F. Brown, B. A. Vallance +2 more
2003Traffic : the International Journal of Intracellular Transport127 citations
Semantic Scholar
Bacterial genetic determinants of non-O157 STEC outbreaks and hemolytic-uremic syndrome after infection.
Mark E. Wickham, C. Lupp, M. Mascarenhas, Alejandra Vázquez +7 more
2006Journal of Infectious Diseases126 citations Open access
Semantic Scholar
Negative regulation of Salmonella pathogenicity island 2 is required for contextual control of virulence during typhoid.
B. Coombes, Mark E. Wickham, M. Lowden, N. F. Brown +1 more
2005Proceedings of the National Academy of Sciences of the United States of America111 citations Open access
Semantic Scholar
Crossing the Line: Selection and Evolution of Virulence Traits
N. F. Brown, Mark E. Wickham, B. Coombes, B. Finlay
2006PLoS Pathogens110 citations Open access
Semantic Scholar
The Salmonella Type III Effector SspH2 Specifically Exploits the NLR Co-chaperone Activity of SGT1 to Subvert Immunity
A. Bhavsar, N. F. Brown, J. Stoepel, M. Wiermer +9 more
2013PLoS Pathogens101 citations Open access
Semantic Scholar
The related effector proteins SopD and SopD2 from Salmonella enterica serovar Typhimurium contribute to virulence during systemic infection of mice
Xiu-Ju Jiang, O. Rossanese, N. F. Brown, Sonya L Kujat-Choy +3 more
2004Molecular Microbiology100 citations
Semantic Scholar
Inhibition of the PtdIns(5) kinase PIKfyve disrupts intracellular replication of Salmonella
M. Kerr, Jack T. H. Wang, N. A. Castro, Nicholas A. Hamilton +6 more
2010EMBO Journal97 citations Open access
Semantic Scholar
SopD acts cooperatively with SopB during Salmonella enterica serovar Typhimurium invasion
M. Bakowski, Judith T. Cirulis, N. F. Brown, B. Finlay +1 more
2007Cellular Microbiology84 citations Open access
Semantic Scholar
Genetic and molecular analysis of GogB, a phage-encoded type III-secreted substrate in Salmonella enterica serovar typhimurium with autonomous expression from its associated phage.
B. Coombes, Mark E. Wickham, N. F. Brown, S. Lemire +4 more
2005Journal of Molecular Biology80 citations
Semantic Scholar
SseL Is a Salmonella-Specific Translocated Effector Integrated into the SsrB-Controlled Salmonella Pathogenicity Island 2 Type III Secretion System
B. Coombes, M. Lowden, Jennifer L. Bishop, Mark E. Wickham +5 more
2006Infection and Immunity73 citations Open access
Semantic Scholar
Salmonella Phage ST64B Encodes a Member of the SseK/NleB Effector Family
N. F. Brown, B. Coombes, Jenna L. Bishop, Mark E. Wickham +6 more
2011PLoS ONE66 citations Open access
Semantic Scholar
Virulence is positively selected by transmission success between mammalian hosts.
Mark E. Wickham, N. F. Brown, Erin C. Boyle, B. Coombes +1 more
2007Current Biology62 citations Open access
Semantic Scholar
Phosphoproteomic Analysis of Salmonella-Infected Cells Identifies Key Kinase Regulators and SopB-Dependent Host Phosphorylation Events
Lindsay D. Rogers, N. F. Brown, Yuan Fang, S. Pelech +1 more
2011Science Signaling61 citations
Semantic Scholar
SseK3 Is a Salmonella Effector That Binds TRIM32 and Modulates the Host’s NF-κB Signalling Activity
Zhe Yang, Amelia T. Soderholm, Tania Wong Fok Lung, Cristina Giogha +4 more
2015PLoS ONE57 citations Open access
Semantic Scholar
Salmonella Effectors SseK1 and SseK3 Target Death Domain Proteins in the TNF and TRAIL Signaling Pathways*
J. M. Newson, Nichollas E. Scott, Ivy Yeuk Wah Chung, Tania Wong Fok Lung +8 more
2018Molecular & Cellular Proteomics52 citations Open access
Semantic Scholar
Molecular Systems Biology Peer Review Process File Interactome Disassembly during Apoptosis Occurs Independent of Caspase Cleavage Editor: Maria Polychronidou Transaction Report
Nichollas E. Scott, Lindsay D. Rogers, A. Prudova, N. F. Brown +4 more
50 citations
Semantic Scholar
Nramp1 expression by dendritic cells modulates inflammatory responses during Salmonella Typhimurium infection
Y. Valdéz, Gretchen E. Diehl, B. A. Vallance, Guntram A. Grassl +6 more
2008Cellular Microbiology48 citations Open access
Semantic Scholar
Oral infection of mice with Salmonella enterica serovar Typhimurium causes meningitis and infection of the brain
Mark E. Wickham, N. F. Brown, J. Provias, B. Finlay +1 more
2007BMC Infectious Diseases46 citations Open access
Semantic Scholar
SseA is required for translocation of Salmonella pathogenicity island-2 effectors into host cells.
B. Coombes, N. F. Brown, Sonya L Kujat-Choy, B. A. Vallance +1 more
2003Microbes and infection43 citations Open access
Semantic Scholar
Global Impact of Salmonella Pathogenicity Island 2-secreted Effectors on the Host Phosphoproteome*
Koshi Imami, A. Bhavsar, Hong-Bing Yu, N. F. Brown +3 more
2013Molecular & Cellular Proteomics42 citations Open access
Semantic Scholar
Adherence of Burkholderia pseudomallei Cells to Cultured Human Epithelial Cell Lines Is Regulated by Growth Temperature
N. F. Brown, J. Boddey, Cameron P. Flegg, I. Beacham
2002Infection and Immunity38 citations Open access
Semantic Scholar
Potential origins and horizontal transfer of type III secretion systems and effectors
N. F. Brown, B. Finlay
2011Mobile Genetic Elements37 citations Open access
Semantic Scholar
Mutational analysis of Salmonella translocated effector members SifA and SopD2 reveals domains implicated in translocation, subcellular localization and function.
N. F. Brown, J. Szeto, Xiu-Ju Jiang, B. Coombes +2 more
2006Microbiology36 citations Open access
Semantic Scholar
Cloning and analysis of genomic differences unique to Burkholderia pseudomallei by comparison with B. thailandensis.
N. F. Brown, I. Beacham
2000Journal of Medical Microbiology36 citations Open access
Semantic Scholar
A Horizontally Acquired Transcription Factor Coordinates Salmonella Adaptations to Host Microenvironments
N. F. Brown, Lindsay D. Rogers, K. Sanderson, J. Gouw +2 more
2014mBio22 citations Open access
Semantic Scholar
Identification of new transposable genetic elements in Burkholderia pseudomallei using subtractive hybridisation.
N. F. Brown, A. Lew, Ifor R. Beacham
2000FEMS Microbiology Letters17 citations Open access
Semantic Scholar
Identification of a novel two-partner secretion system from Burkholderia pseudomallei
N. F. Brown, C. Logue, J. Boddey, R. Scott +2 more
2004Zeitschrift für Induktive Abstammungs- und Vererbungslehre15 citations
Semantic Scholar
Searching for virulence Burkholderia pseudomallei genes by immunoscreening the lambda ZAPII expressed genomic library.
S. Jitsurong, C. Chirathaworn, N. F. Brown, I. Beacham +1 more
2003Southeast Asian Journal of Tropical Medicine and Public Health6 citations
Semantic Scholar
Src homology domain 2 adaptors affect adherence of Salmonella enterica serovar Typhimurium to non-phagocytic cells.
Erin C. Boyle, N. F. Brown, J. Brumell, B. Finlay
2007Microbiology4 citations Open access
Semantic Scholar
Investigation of a Cluster of ST22 MRSA Transmission in a Community Setting
M. Toleman, B. Blane, E. Harrison, F. Coll +3 more
20170 citations
Semantic Scholar
Erratum
J. Brumell, Sonya L Kujat-Choy, N. F. Brown, B. A. Vallance +2 more
20030 citations
Semantic Scholar

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