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O. Ernst · SciRah

Researcher profile · Semantic Scholar

O. Ernst

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O. Ernst — researcher profile on SciRah

h-index: 44
Works: 149
Citations: 10K

Most-cited papers

Microbial and Animal Rhodopsins: Structures, Functions, and Molecular Mechanisms
O. Ernst, D. Lodowski, M. Elstner, P. Hegemann +2 more
2013Chemical Reviews1,024 citations Open access
Semantic Scholar
Crystal structure of metarhodopsin II
H. Choe, Y. Kim, J. Park, T. Morizumi +5 more
2011Nature653 citations
Semantic Scholar
Activation of the A2A adenosine G-protein-coupled receptor by conformational selection
Li-Bin Ye, N. Van Eps, Marco Zimmer, O. Ernst +1 more
2016Nature332 citations
Semantic Scholar
Crystal structure of pre-activated arrestin p44
Y. Kim, K. Hofmann, O. Ernst, P. Scheerer +2 more
2013Nature172 citations
Semantic Scholar
Mechanistic insights into allosteric regulation of the A2A adenosine G protein-coupled receptor by physiological cations
Li-Bin Ye, Chris Neale, Adnan Sljoka, B. Lyda +8 more
2018Nature Communications150 citations Open access
Semantic Scholar
Structure of the glucagon receptor in complex with a glucagon analogue
Hao-Nan Zhang, Anna Qiao, Lin-Lin Yang, N. Van Eps +18 more
2018Nature141 citations
Semantic Scholar
Crystallogenesis of Membrane Proteins Mediated by Polymer-Bounded Lipid Nanodiscs.
J. Broecker, B. Eger, O. Ernst
2017Structure131 citations Open access
Semantic Scholar
Conformation of receptor-bound visual arrestin
Miyeon Kim, S. Vishnivetskiy, N. Van Eps, Nathan Alexander +8 more
2012Proceedings of the National Academy of Sciences of the United States of America116 citations Open access
Semantic Scholar
Low-dose fixed-target serial synchrotron crystallography
R. Owen, D. Axford, D. Sherrell, A. Kuo +4 more
2017Acta Crystallographica Section D: Structural Biology97 citations Open access
Semantic Scholar
Conformational equilibria of light-activated rhodopsin in nanodiscs
N. Van Eps, Lydia N. Caro, T. Morizumi, A. Kusnetzow +6 more
2017Proceedings of the National Academy of Sciences of the United States of America90 citations Open access
Semantic Scholar
Effect of channel mutations on the uptake and release of the retinal ligand in opsin
Ronny Piechnick, E. Ritter, P. Hildebrand, O. Ernst +3 more
2012Proceedings of the National Academy of Sciences of the United States of America82 citations Open access
Semantic Scholar
Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound β1-Adrenergic Receptor
M. Su, Lan Zhu, Yixiao Zhang, N. Paknejad +12 more
2020Molecules and Cells77 citations Open access
Semantic Scholar
Opsin, a structural model for olfactory receptors?
J. Park, T. Morizumi, Yafang Li, Joo Eun Hong +4 more
2013Angewandte Chemie76 citations
Semantic Scholar
Gi- and Gs-coupled GPCRs show different modes of G-protein binding
N. Van Eps, C. Altenbach, Lydia N. Caro, N. R. Latorraca +4 more
2018Proceedings of the National Academy of Sciences of the United States of America69 citations Open access
Semantic Scholar
Cryo-EM structure of the native rhodopsin dimer in nanodiscs
Dorothy Y. Zhao, Matthias Pöge, T. Morizumi, S. Gulati +9 more
2019Journal of Biological Chemistry64 citations Open access
Semantic Scholar
X-ray Crystallographic Structure and Oligomerization of Gloeobacter Rhodopsin
T. Morizumi, Wei-Lin Ou, N. Van Eps, Keiichi Inoue +3 more
2019Scientific Reports61 citations Open access
Semantic Scholar
Intracellular localization of the proteasome in response to stress conditions
C. Enenkel, Ryulyi Kang, Florian Wilfling, O. Ernst
2022Journal of Biological Chemistry55 citations Open access
Semantic Scholar
High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions
J. Broecker, T. Morizumi, Wei-Lin Ou, Viviane Klingel +9 more
2018Nature Protocols50 citations
Semantic Scholar
G protein–coupled receptor modulation with pepducins: moving closer to the clinic
P. Dimond, K. Carlson, M. Bouvier, C. Gerard +11 more
2011Annals of the New York Academy of Sciences45 citations Open access
Semantic Scholar
Genetically Encoded Quinone Methides Enabling Rapid, Site-specific, and Photo-controlled Protein Modification with Amine Reagents
Jun Liu, Rujin Cheng, N. Van Eps, Nanxi Wang +6 more
2020Journal of the American Chemical Society42 citations Open access
Semantic Scholar
Coupling of G Proteins to Reconstituted Monomers and Tetramers of the M2 Muscarinic Receptor*
Dar'ya S. Redka, T. Morizumi, Gwendolynne Elmslie, Pranavan Paranthaman +4 more
2014Journal of Biological Chemistry41 citations Open access
Semantic Scholar
TakeTwo: an indexing algorithm suited to still images with known crystal parameters
H. Ginn, P. Roedig, A. Kuo, G. Evans +6 more
2016Acta Crystallographica Section D: Structural Biology38 citations Open access
Semantic Scholar
Phospholipid scrambling by rhodopsin
O. Ernst, A. Menon
2015Photochemical and Photobiological Sciences37 citations Open access
Semantic Scholar
The photocycle and ultrafast vibrational dynamics of bacteriorhodopsin in lipid nanodiscs.
P. Johnson, Alexei Halpin, T. Morizumi, L. Brown +3 more
2014Physical Chemistry, Chemical Physics - PCCP35 citations
Semantic Scholar
Conserved Tyr223(5.58) plays different roles in the activation and G-protein interaction of rhodopsin.
Matthias Elgeti, Roman Kazmin, Martin Heck, T. Morizumi +6 more
2011Journal of the American Chemical Society33 citations
Semantic Scholar
Accessible virtual reality of biomolecular structural models using the Autodesk Molecule Viewer
A. R. Balo, Merry Wang, O. Ernst
2017Nature Methods28 citations
Semantic Scholar
Light-independent phospholipid scramblase activity of bacteriorhodopsin from Halobacterium salinarum
A. Verchère, Wei-Lin Ou, B. Ploier, T. Morizumi +5 more
2017Scientific Reports27 citations Open access
Semantic Scholar
Structural evidence for visual arrestin priming via complexation of phosphoinositols
C. L. Sander, Jennings C. Luu, Kyumhyuk Kim, D. Furkert +11 more
2021Structure26 citations Open access
Semantic Scholar
Excited-State Vibronic Dynamics of Bacteriorhodopsin from Two-Dimensional Electronic Photon Echo Spectroscopy and Multiconfigurational Quantum Chemistry
S. Gozem, P. Johnson, Alexei Halpin, Hoi L. Luk +5 more
2020Journal of Physical Chemistry Letters26 citations Open access
Semantic Scholar
Recent advances in biophysical studies of rhodopsins - Oligomerization, folding, and structure.
L. Brown, O. Ernst
2017Biochimica et Biophysica Acta - Proteins and Proteomics26 citations
Semantic Scholar
A Versatile System for High-Throughput In Situ X-ray Screening and Data Collection of Soluble and Membrane-Protein Crystals
J. Broecker, Viviane Klingel, Wei-Lin Ou, A. R. Balo +4 more
2016Crystal Growth & Design25 citations Open access
Semantic Scholar
Mapping the conformational landscape of the stimulatory heterotrimeric G protein
S. K. Huang, Louis-Philippe Picard, Rima S. M. Rahmatullah, Aditya Pandey +5 more
2023Nature Structural & Molecular Biology24 citations
Semantic Scholar
Structures of channelrhodopsin paralogs in peptidiscs explain their contrasting K+ and Na+ selectivities
T. Morizumi, Kyumhyuk Kim, Hai Li, E. Govorunova +9 more
2023Nature Communications23 citations Open access
Semantic Scholar
7TM Domain Structure of Adhesion GPCRs.
C. de Graaf, S. Nijmeijer, Steffen Wolf, O. Ernst
2016Handbook of Experimental Pharmacology19 citations
Semantic Scholar
Engineering of an Artificial Light-Modulated Potassium Channel
Lydia N. Caro, Christophe J. Moreau, Argel Estrada-Mondragón, O. Ernst +1 more
2012PLoS ONE19 citations Open access
Semantic Scholar
Low pH structure of heliorhodopsin reveals chloride binding site and intramolecular signaling pathway
J. Besaw, Jörg Reichenwallner, P. de Guzman, A. Tučs +6 more
2022Scientific Reports17 citations Open access
Semantic Scholar
Toward Precise Interpretation of DEER-Based Distance Distributions: Insights from Structural Characterization of V1 Spin-Labeled Side Chains.
A. R. Balo, Hannes Feyrer, O. Ernst
2016Biochemistry17 citations Open access
Semantic Scholar
Characterizing rhodopsin signaling by EPR spectroscopy: from structure to dynamics
N. Van Eps, Lydia N. Caro, T. Morizumi, O. Ernst
2015Photochemical and Photobiological Sciences14 citations
Semantic Scholar
A Novel Polar Core and Weakly Fixed C-Tail in Squid Arrestin Provide New Insight into Interaction with Rhodopsin.
A. Bandyopadhyay, N. Van Eps, B. Eger, Sarah Rauscher +7 more
2018Journal of Molecular Biology13 citations Open access
Semantic Scholar
Rapid and facile recombinant expression of bovine rhodopsin in HEK293S GnTI(-) cells using a PiggyBac inducible system.
Lydia N. Caro, Zhi-Jie Li, A. R. Balo, N. Van Eps +2 more
2015Methods in Enzymology13 citations
Semantic Scholar
Broadly neutralizing humanized SARS-CoV-2 antibody binds to a conserved epitope on Spike and provides antiviral protection through inhalation-based delivery in non-human primates
Paule Hermet, B. Delache, Cécile Herate, Esther Wolf +26 more
2023PLoS Pathogens10 citations Open access
Semantic Scholar
Electron paramagnetic resonance spectroscopy on G-protein-coupled receptors: Adopting strategies from related model systems.
Jörg Reichenwallner, Boyuan Liu, A. R. Balo, Wei-Lin Ou +1 more
2021Current Opinion in Structural Biology10 citations
Semantic Scholar
Synthesis of Chiral Spin-Labeled Amino Acids.
Wayne Vuong, Fabricio Mosquera-Guagua, Randy Sanichar, Tyler McDonald +3 more
2019Organic Letters9 citations
Semantic Scholar
Structural Basis of the Activation of Heterotrimeric Gs-protein by Isoproterenol-bound Beta1-Adrenergic Receptor
M. Su, L. Zhu, Y. Zhang, N. Paknejad +12 more
20208 citations
Semantic Scholar
Utilizing tagged paramagnetic shift reagents to monitor protein dynamics by NMR.
Li-Bin Ye, N. Van Eps, X. Li, O. Ernst +1 more
2017Biochimica et Biophysica Acta - Proteins and Proteomics7 citations
Semantic Scholar
X-ray transparent microfluidic chips for high-throughput screening and optimization of in meso membrane protein crystallization.
Jeremy M. Schieferstein, Ashtamurthy S. Pawate, Chang Sun, F. Wan +5 more
2017Biomicrofluidics6 citations Open access
Semantic Scholar
Publisher Correction: Cryo-EM structure of human rhodopsin bound to an inhibitory G protein
Yan-Yong Kang, Oleg Kuybeda, P. de Waal, S. Mukherjee +17 more
2018Nature4 citations Open access
Semantic Scholar
Stationary Phase EPR Spectroscopy for Monitoring Membrane Protein Refolding by Conformational Response.
A. R. Balo, Jinyoung Lee, O. Ernst
2018Analytical Chemistry3 citations Open access
Semantic Scholar
Active Conformations of Arrestins: Expected and Unexpected Changes
A. Bandyopadhyay, Ya Zhuo, W. Hubbell, C. Klug +2 more
20172 citations
Semantic Scholar
Mixed Potential Energy Surfaces of the Ultrafast Isomerization of Retinal in Bacteriorhodopsin
P. Johnson, Alexei Halpin, T. Morizumi, V. Prokhorenko +2 more
20132 citations Open access
Semantic Scholar

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