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R. Lawlor · SciRah

Researcher profile · Semantic Scholar

R. Lawlor

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R. Lawlor — researcher profile on SciRah

h-index: 50
Works: 223
Citations: 18K

Most-cited papers

Non-functional pancreatic neuroendocrine tumours: ATRX/DAXX and alternative lengthening of telomeres (ALT) are prognostically independent from ARX/PDX1 expression and tumour size
W. Hackeng, L. Brosens, J. Kim, Roderick J. O’Sullivan +52 more
2021Gut135 citations Open access
Semantic Scholar
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer
Jessica L. Chitty, Michelle Yam, L. Perryman, Amelia L. Parker +126 more
2023Nature Cancer132 citations Open access
Semantic Scholar
Tumor Mutational Burden as a Potential Biomarker for Immunotherapy in Pancreatic Cancer: Systematic Review and Still-Open Questions
R. Lawlor, P. Mattiolo, A. Mafficini, Seung-Mo Hong +12 more
2021Cancers118 citations Open access
Semantic Scholar
Bioengineered 3D models of human pancreatic cancer recapitulate in vivo tumour biology
D. Osuna de la Peña, S. Trabulo, E. Collin, Y. Liu +9 more
2021Nature Communications114 citations Open access
Semantic Scholar
Neutralization of NET-associated human ARG1 enhances cancer immunotherapy
S. Canè, Roza Maria Barouni, M. Fabbi, J. Cuozzo +16 more
2023Science Translational Medicine109 citations Open access
Semantic Scholar
MYC ecDNA promotes intratumour heterogeneity and plasticity in PDAC
Elena Fiorini, A. Malinova, Daniel Schreyer, Davide Pasini +28 more
2025Nature65 citations Open access
Semantic Scholar
DNA methylation patterns identify subgroups of pancreatic neuroendocrine tumors with clinical association
V. Lakis, R. Lawlor, F. Newell, A. Patch +34 more
2021Communications Biology49 citations Open access
Semantic Scholar
IL17A critically shapes the transcriptional program of fibroblasts in pancreatic cancer and switches on their protumorigenic functions
G. Mucciolo, C. Curcio, C. Roux, Wanda Li +14 more
2021Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Dysregulated splicing factor SF3B1 unveils a dual therapeutic vulnerability to target pancreatic cancer cells and cancer stem cells with an anti-splicing drug
E. Alors-Pérez, R. Blázquez-Encinas, S. Alcalá, C. Viyuela-García +22 more
2021Journal of experimental & clinical cancer research : CR44 citations Open access
Semantic Scholar
Expression of the membrane tetraspanin claudin 18 on cancer cells promotes T lymphocyte infiltration and antitumor immunity in pancreatic cancer.
Francesco De Sanctis, Silvia Dusi, S. Caligola, Cristina Anselmi +24 more
2024Immunity40 citations Open access
Semantic Scholar
Differential activity of MAPK signalling defines fibroblast subtypes in pancreatic cancer
L. Veghini, Davide Pasini, Rui Fang, P. Delfino +20 more
2023bioRxiv40 citations Open access
Semantic Scholar
Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer
Francesco De Sanctis, A. Lamolinara, F. Boschi, C. Musiu +29 more
2022Journal for ImmunoTherapy of Cancer40 citations Open access
Semantic Scholar
Genome‐wide scan of long noncoding RNA single nucleotide polymorphisms and pancreatic cancer susceptibility
C. Corradi, M. Gentiluomo, L. Gajdán, G. Cavestro +50 more
2021International Journal of Cancer33 citations Open access
Semantic Scholar
Treatment of advanced gastroenteropancreatic neuroendocrine neoplasia, are we on the way to personalised medicine?
A. Rinke, C. Auernhammer, L. Bodei, M. Kidd +10 more
2021Gut33 citations
Semantic Scholar
A Self‐Assembled 3D Model Demonstrates How Stiffness Educates Tumor Cell Phenotypes and Therapy Resistance in Pancreatic Cancer
Ying Liu, Babatunde O. Okesola, D. Osuna de la Peña, Wei-Qi Li +11 more
2024Advanced Healthcare Materials30 citations Open access
Semantic Scholar
Genetic and non-genetic risk factors for early-onset pancreatic cancer.
Ylenia Nodari, M. Gentiluomo, B. Mohelníková-Duchoňová, E. Kreivenaite +63 more
2023Digestive and Liver Disease30 citations Open access
Semantic Scholar
CXCR1/2 dual-inhibitor ladarixin reduces tumour burden and promotes immunotherapy response in pancreatic cancer
G. Piro, C. Carbone, Antonio Agostini, A. Esposito +13 more
2022British Journal of Cancer28 citations Open access
Semantic Scholar
Alternative Lengthening of Telomeres (ALT) in Pancreatic Neuroendocrine Tumors: Ready for Prime-Time in Clinical Practice?
C. Luchini, R. Lawlor, Samantha Bersani, C. Vicentini +6 more
2021Current Oncology Reports27 citations Open access
Semantic Scholar
Genome‐wide association study identifies an early onset pancreatic cancer risk locus
D. Campa, M. Gentiluomo, O. Obazee, A. Ballerini +55 more
2020International Journal of Cancer27 citations Open access
Semantic Scholar
Associations between pancreatic expression quantitative traits and risk of pancreatic ductal adenocarcinoma.
L. Pistoni, M. Gentiluomo, Ye Lu, Evangelina López de Maturana +53 more
2021Carcinogenesis26 citations Open access
Semantic Scholar
Pentraxin 3 is a stromally-derived biomarker for detection of pancreatic ductal adenocarcinoma
M. Goulart, J. Watt, I. Siddiqui, R. Lawlor +13 more
2021npj Precision Oncology26 citations Open access
Semantic Scholar
The impact of GDPR on data sharing for European cancer research.
R. Lawlor
2022The Lancet Oncology25 citations
Semantic Scholar
GRAd-COV2, a gorilla adenovirus-based candidate vaccine against COVID-19, is safe and immunogenic in younger and older adults
S. Lanini, S. Capone, A. Antinori, S. Milleri +64 more
2021Science Translational Medicine24 citations Open access
Semantic Scholar
Genomic characterization of hepatoid tumors: context matters.
R. Lawlor, A. Mafficini, Concetta Sciammarella, C. Cantù +31 more
2021Human Pathology24 citations
Semantic Scholar
Histo-molecular characterization of pancreatic cancer with microsatellite instability: intra-tumor heterogeneity, B2M inactivation, and the importance of metastatic sites
C. Luchini, A. Mafficini, D. Chatterjee, M. Piredda +16 more
2021Virchows Archiv23 citations
Semantic Scholar
SWI/SNF COMPLEX-DEFICIENT UNDIFFERENTIATED CARCINOMA OF THE PANCREAS: CLINICOPATHOLOGIC AND GENOMIC ANALYSIS
A. Yavas, Kerem Ozcan, N. Adsay, S. Balci +19 more
2024Modern Pathology22 citations Open access
Semantic Scholar
Solid Pseudopapillary Neoplasm of the Pancreas and Abdominal Desmoid Tumor in a Patient Carrying Two Different BRCA2 Germline Mutations: New Horizons from Tumor Molecular Profiling
A. Mafficini, R. Lawlor, C. Ghimenton, D. Antonello +10 more
2021Genes22 citations Open access
Semantic Scholar
IDH-wild type glioblastomas featuring at least 30% giant cells are characterized by frequent RB1 and NF1 alterations and hypermutation
V. Barresi, M. Simbolo, A. Mafficini, M. Martini +11 more
2021Acta Neuropathologica Communications21 citations Open access
Semantic Scholar
Association between a polymorphic variant in the CDKN2B‐AS1/ANRIL gene and pancreatic cancer risk
M. Giaccherini, R. Farinella, M. Gentiluomo, B. Mohelníková-Duchoňová +43 more
2022International Journal of Cancer19 citations Open access
Semantic Scholar
The Impact of Molecular Subtyping on Pathological Staging of Pancreatic Cancer
S. Dreyer, Sarah Rae, K. Bisset, R. Upstill-Goddard +18 more
2021Annals of Surgery19 citations Open access
Semantic Scholar
Polymorphic variants involved in methylation regulation: a strategy to discover risk loci for pancreatic ductal adenocarcinoma
C. Corradi, G. Lencioni, M. Gentiluomo, Alessio Felici +58 more
2023Journal of Medical Genetics17 citations Open access
Semantic Scholar
Integrative characterization of intraductal tubulopapillary neoplasm (ITPN) of the pancreas and associated invasive adenocarcinoma
A. Mafficini, M. Simbolo, T. Shibata, Seung-Mo Hong +23 more
2022Modern Pathology17 citations Open access
Semantic Scholar
Association of Genetic Variants Affecting microRNAs and Pancreatic Cancer Risk
Ye Lu, C. Corradi, M. Gentiluomo, Evangelina López de Maturana +73 more
2021Frontiers in Genetics17 citations Open access
Semantic Scholar
Axon guidance cue SEMA3A promotes the aggressive phenotype of basal-like PDAC
F. Lupo, F. Pezzini, Davide Pasini, Elena Fiorini +21 more
2024Gut16 citations Open access
Semantic Scholar
Loss of FGFR4 promotes the malignant phenotype of PDAC
S. D'Agosto, F. Pezzini, L. Veghini, P. Delfino +22 more
2022Oncogene15 citations Open access
Semantic Scholar
Harnessing the epigenome to boost immunotherapy response in non-small cell lung cancer patients
A. Gkountakos, P. Delfino, R. Lawlor, A. Scarpa +2 more
2021Therapeutic Advances in Medical Oncology15 citations Open access
Semantic Scholar
Spliceosomic dysregulation in pancreatic cancer uncovers splicing factors PRPF8 and RBMX as novel candidate actionable targets
E. Alors-Pérez, R. Blázquez-Encinas, M. Moreno-Montilla, V. García-Vioque +16 more
2024Molecular Oncology14 citations Open access
Semantic Scholar
Common variability in oestrogen-related genes and pancreatic ductal adenocarcinoma risk in women
G. Peduzzi, L. Archibugi, V. Katzke, M. Gentiluomo +40 more
2022Scientific Reports14 citations Open access
Semantic Scholar
ROR1 and ROR2 expression in pancreatic cancer
Dong-Li Liu, G. Sharbeen, P. Phillips, A. Johns +85 more
2021BMC Cancer14 citations Open access
Semantic Scholar
Genomic characterization of undifferentiated sarcomatoid carcinoma of the pancreas.
A. Gkountakos, A. Mafficini, E. Lou, G. Malleo +20 more
2022Human Pathology13 citations
Semantic Scholar
Identification of Recessively Inherited Genetic Variants Potentially Linked to Pancreatic Cancer Risk
Ye Lu, M. Gentiluomo, A. Macauda, D. Gioffreda +65 more
2021Frontiers in Oncology13 citations Open access
Semantic Scholar
Clinical and Genomic Characterization of Pancreatic Ductal Adenocarcinoma with Signet-Ring / Poorly Cohesive Cells.
M. Simbolo, N. Silvestris, G. Malleo, A. Mafficini +28 more
2023Modern Pathology12 citations Open access
Semantic Scholar
Accelerating equitable cancer genomics and precision oncology in health care and research: a Lancet Oncology Commission.
R. Casolino, J. Mateo, E. D. de Vries, A. Johns +52 more
2026The Lancet Oncology11 citations Open access
Semantic Scholar
Pancreatic cancer acquires resistance to MAPK pathway inhibition by clonal expansion and adaptive DNA hypermethylation
Laura K. Godfrey, Jan Forster, S. Liffers, Christopher Schröder +15 more
2024Clinical Epigenetics11 citations Open access
Semantic Scholar
ICGC-ARGO precision medicine: familial matters in pancreatic cancer.
M. Milella, C. Luchini, R. Lawlor, A. Johns +3 more
2022The Lancet Oncology10 citations
Semantic Scholar
Genetically Determined Telomere Length Is Associated with Pancreatic Neuroendocrine Neoplasms Onset
M. Gentiluomo, G. Capurso, L. Morelli, S. Ermini +21 more
2022Neuroendocrinology10 citations
Semantic Scholar
Colorectal cancer with microsatellite instability: Right-sided location and signet ring cell histology are associated with nodal metastases, and extranodal extension influences disease-free survival.
M. Piredda, S. Ammendola, Concetta Sciammarella, G. Turri +15 more
2021Pathology, Research and Practice10 citations Open access
Semantic Scholar
Accelerating cancer omics and precision oncology in health care and research: a Lancet Oncology Commission.
R. Casolino, A. Johns, Mélanie Courtot, R. Lawlor +14 more
2023The Lancet Oncology9 citations Open access
Semantic Scholar
A scan of all coding region variants of the human genome, identifies 13q12.2-rs9579139 and 15q24.1-rs2277598 as novel risk loci for pancreatic ductal adenocarcinoma.
M. Giaccherini, Leonardo Gori, M. Gentiluomo, R. Farinella +57 more
2023Carcinogenesis9 citations Open access
Semantic Scholar
Gα15 in early onset of pancreatic ductal adenocarcinoma
G. Innamorati, T. Wilkie, G. Malpeli, S. Paiella +21 more
2021Scientific Reports9 citations Open access
Semantic Scholar

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