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L. Otero · SciRah

Researcher profile · Semantic Scholar

L. Otero

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L. Otero — researcher profile on SciRah

h-index: 13
Works: 78
Citations: 1,052

Most-cited papers

How allosteric control of Staphylococcus aureus penicillin binding protein 2a enables methicillin resistance and physiological function
L. Otero, A. Rojas-Altuve, L. I. Llarrull, C. Carrasco-López +11 more
2013Proceedings of the National Academy of Sciences of the United States of America273 citations Open access
Semantic Scholar
Discovery of Antibiotic (E)-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3H)-one
R. Bouley, M. Kumarasiri, Zhi-Hong Peng, L. Otero +11 more
2015Journal of the American Chemical Society147 citations Open access
Semantic Scholar
Disruption of Allosteric Response as an Unprecedented Mechanism of Resistance to Antibiotics
Jennifer Fishovitz, A. Rojas-Altuve, L. Otero, Matthew Dawley +4 more
2014Journal of the American Chemical Society80 citations Open access
Semantic Scholar
Structure of the Full-Length Bacteriophytochrome from the Plant Pathogen Xanthomonas campestris Provides Clues to its Long-Range Signaling Mechanism.
L. Otero, S. Klinke, J. Rinaldi, Francisco Velázquez-Escobar +7 more
2016Journal of Molecular Biology78 citations Open access
Semantic Scholar
The disruptive effect of lysozyme on the bacterial cell wall explored by an in‐silico structural outlook
E. Primo, L. Otero, F. Ruíz, S. Klinke +1 more
2018Biochemistry and Molecular Biology Education72 citations Open access
Semantic Scholar
Biological Crystallography Structural Basis for the Broad Specificity of a New Family of Amino-acid Racemases
Akbar Espaillat, César, Bernardo-García, N. Pietrosemoli +7 more
63 citations
Semantic Scholar
Development of a hyperimmune equine serum therapy for COVID-19 in Argentina.
V. Zylberman, Santiago Sanguineti, A. Pontoriero, S. Higa +43 more
2020Medicina53 citations
Semantic Scholar
The Reaction Mechanism of Metallo-β-Lactamases Is Tuned by the Conformation of an Active-Site Mobile Loop
Antonela R. Palacios, M. F. Mojica, E. Giannini, M. Taracila +7 more
2018Antimicrobial Agents and Chemotherapy31 citations Open access
Semantic Scholar
Structural basis for the Pr-Pfr long-range signaling mechanism of a full-length bacterial phytochrome at the atomic level
L. Otero, S. Foscaldi, Giuliano T. Antelo, Germán L. Rosano +12 more
2021bioRxiv25 citations Open access
Semantic Scholar
A Pseudomonas aeruginosa PAO1 acetylcholinesterase is encoded by the PA4921 gene and belongs to the SGNH hydrolase family.
D. Sánchez, L. Otero, C. Hernández, Ana Luz Serra +3 more
2012Microbiology Research21 citations Open access
Semantic Scholar
Snapshots of Conformational Changes Shed Light into the NtrX Receiver Domain Signal Transduction Mechanism.
I. Fernández, L. Otero, S. Klinke, Mariela del Carmen Carrica +1 more
2015Journal of Molecular Biology17 citations Open access
Semantic Scholar
Critical Active-Site Residues Identified by Site-Directed Mutagenesis in Pseudomonas aeruginosa Phosphorylcholine Phosphatase, A New Member of the Haloacid Dehalogenases Hydrolase Superfamily
Paola R. Beassoni, L. Otero, M. J. Massimelli, Á. T. Lisa +1 more
2006Current Microbiology15 citations
Semantic Scholar
Using a molecular model and kinetic experiments in the presence of divalent cations to study the active site and catalysis of Pseudomonas aeruginosa phosphorylcholine phosphatase.
Paola R. Beassoni, L. Otero, Á. T. Lisa, C. Domenech
2008Biochimica et Biophysica Acta13 citations
Semantic Scholar
Dimer Asymmetry and Light Activation Mechanism in Brucella Blue-Light Sensor Histidine Kinase
J. Rinaldi, I. Fernández, Heewhan Shin, G. Sycz +10 more
2021mBio12 citations Open access
Semantic Scholar
Exaptation of two ancient immune proteins into a new dimeric pore-forming toxin in snails
M. Giglio, S. Ituarte, Verônica Milesi, M. Dreon +7 more
2019bioRxiv11 citations Open access
Semantic Scholar
Crystallization and preliminary X-ray characterization of the full-length bacteriophytochrome from the plant pathogen Xanthomonas campestris pv. campestris.
S. Klinke, L. Otero, J. Rinaldi, S. Sosa +4 more
2014Acta Crystallographica Section F Structural Biology Communications10 citations Open access
Semantic Scholar
Transition from octahedral to tetrahedral geometry causes the activation or inhibition by Zn2+ of Pseudomonas aeruginosa phosphorylcholine phosphatase
L. Otero, Paola R. Beassoni, Á. T. Lisa, C. Domenech
2010Biometals10 citations
Semantic Scholar
Solution and crystal structure of BA42, a protein from the Antarctic bacterium Bizionia argentinensis comprised of a stand‐alone TPM domain
M. Aran, Clara Smal, L. Pellizza, Mariana Gallo +8 more
2014Proteins: Structure, Function, and Bioinformatics9 citations Open access
Semantic Scholar
Structural and functional characterization of a cold adapted TPM-domain with ATPase/ADPase activity.
M. Cerutti, L. Otero, Clara Smal, L. Pellizza +3 more
2017Journal of Structural Biology8 citations Open access
Semantic Scholar
The structural domains of Pseudomonas aeruginosa phosphorylcholine phosphatase cooperate in substrate hydrolysis: 3D structure and enzymatic mechanism.
L. Infantes, L. Otero, Paola R. Beassoni, Cristhian Boetsch +3 more
2012Journal of Molecular Biology8 citations Open access
Semantic Scholar
Site-directed mutations and kinetic studies show key residues involved in alkylammonium interactions and reveal two sites for phosphorylcholine in Pseudomonas aeruginosa phosphorylcholine phosphatase.
Paola R. Beassoni, L. Otero, Cristhian Boetsch, C. Domenech +2 more
2011Biochimica et Biophysica Acta8 citations
Semantic Scholar
Cross-protection and cross-neutralization capacity of ancestral and VOC-matched SARS-CoV-2 adenoviral vector-based vaccines
Sabrina E. Vinzón, M. V. Lopez, Eduardo G. A. Cafferata, A. Soto +22 more
2023npj Vaccines7 citations Open access
Semantic Scholar
Deamidation drives molecular aging of the SARS-CoV-2 spike protein receptor-binding motif
Ramiro Lorenzo, L. Defelipe, Lucio Aliperti, S. Niebling +10 more
2021Journal of Biological Chemistry7 citations Open access
Semantic Scholar
Engineering a bifunctional copper site in the cupredoxin fold by loop-directed mutagenesis
Andrés Espinoza-Cara, Ulises A. Zitare, D. Alvarez-Paggi, S. Klinke +3 more
2018Chemical Science7 citations Open access
Semantic Scholar
Draft Genome Sequence of Methylobacterium sp. Strain V23, Isolated from Accretion Ice of the Antarctic Subglacial Lake Vostok
Amanda Sapp, J. Huguet-Tapia, M. Sánchez-Lamas, Giuliano T. Antelo +7 more
2018Genome Announcements7 citations Open access
Semantic Scholar
Different Effects of Mg2+ and Zn2+ on the Two Sites for Alkylammonium Compounds in Pseudomonas aeruginosa Phosphorylcholine Phosphatase
L. Otero, Paola R. Beassoni, Cristhian Boetsch, Á. T. Lisa +1 more
2011Enzyme Research7 citations Open access
Semantic Scholar
Crystallization and preliminary X-ray diffraction analysis of Pseudomonas aeruginosa phosphorylcholine phosphatase.
L. Otero, Paola R. Beassoni, C. Domenech, Á. T. Lisa +1 more
2010Acta Crystallographica. Section F : Structural Biology and Crystallization Communications7 citations Open access
Semantic Scholar
Structural and mutational analyses of the Leptospira interrogans virulence-related heme oxygenase provide insights into its catalytic mechanism
A. Soldano, S. Klinke, L. Otero, M. Rivera +2 more
2017PLoS ONE6 citations Open access
Semantic Scholar
A Glance on Pseudomonas aeruginosa Phosphorylcholine Phosphatase, an Enzyme whose Synthesis Depends on the Presence of Choline in its Environment
Á. T. Lisa, Paola R. Beassoni, M. J. Massimelli, L. Otero +1 more
20076 citations
Semantic Scholar
Pr‐favoured variants of the bacteriophytochrome from the plant pathogen Xanthomonas campestris hint on light regulation of virulence‐associated mechanisms
V. Conforte, L. Otero, L. Toum, S. Sirigu +9 more
2021The FEBS Journal5 citations Open access
Semantic Scholar
A Spectroscopy‐based Methodology for Rapid Screening and Characterization of Phytochrome Photochemistry in Search of Pfr‐favored Variants
Giuliano T. Antelo, M. Sánchez-Lamas, F. Goldbaum, L. Otero +2 more
2020Photochemistry and Photobiology5 citations Open access
Semantic Scholar
Prevention of tubulin/aldose reductase association delays the development of pathological complications in diabetic rats
Juan F. Rivelli Antonelli, V. Santander, Ayelén D. Nigra, N. E. Monesterolo +4 more
2021Journal of physiology and biochemistry4 citations Open access
Semantic Scholar
Preparation and biophysical characterization of recombinant Pseudomonas aeruginosa phosphorylcholine phosphatase.
Paola R. Beassoni, Federico Javier Pérez de Berti, L. Otero, V. Risso +4 more
2010Protein Expression and Purification4 citations
Semantic Scholar
Cryo-EM structures of engineered Shiga toxin-based immunogens capable of eliciting neutralizing antibodies with therapeutic potential against Hemolytic Uremic Syndrome
A. E. Cristófalo, Arvind Sharma, M. L. Cerutti, Kedar Sharma +6 more
2024bioRxiv3 citations
Semantic Scholar
A Fijivirus Major Viroplasm Protein Shows RNA-Stimulated ATPase Activity by Adopting Pentameric and Hexameric Assemblies of Dimers
G. Llauger, R. Melero, Demián Monti, G. Sycz +15 more
2022bioRxiv3 citations Open access
Semantic Scholar
A disordered region retains the full protease inhibitor activity and the capacity to induce CD8+ T cells in vivo of the oral vaccine adjuvant U-Omp19
M. L. Darriba, Celeste Pueblas Castro, L. Coria, Laura A. Bruno +7 more
2022Computational and Structural Biotechnology Journal3 citations Open access
Semantic Scholar
Crystal structures of peanut lectin in the presence of synthetic β-N- and β-S-galactosides disclose evidences for the recognition of different glycomimetic ligands
Alejandro J. Cagnoni, E. Primo, S. Klinke, M. E. Cano +6 more
2020bioRxiv2 citations Open access
Semantic Scholar
Desarrollo de un suero equino hiperinmune para el tratamiento de COVID-19 en Argentina
V. Zylberman, Santiago Sanguineti, A. Pontoriero, S. Higa +43 more
20202 citations
Semantic Scholar
Cryo‐EM structure of N‐glycosylated Pomacea canaliculata hemocyanin provides insights into its role in the immune response of gastropods
Tabata R. Brola, Ignacio Rafael Chiumiento, S. Ituarte, Guillermo I. Benítez +5 more
2025The FEBS Journal1 citations Open access
Semantic Scholar
An All‐Inclusive and Straightway Laboratory Activity to Solve the Three‐Dimensional Crystal Structure of a Protein
S. Klinke, J. Rinaldi, F. Goldbaum, S. Suárez +1 more
2019Biochemistry and Molecular Biology Education1 citations Open access
Semantic Scholar
Hemocyanin-Mediated Immunity in Pomacea canaliculata: Exploring a Potential Source of Antimicrobial Peptides.
Ignacio Rafael Chiumiento, K. B. Soldati, Tabata R. Brola, Lucio Bender +4 more
2026Fish and Shellfish Immunology0 citations
Semantic Scholar
Characterizing Phytochrome Photochemistry Using UV-Visible Spectroscopy in Host Cell Extracts and Purified Protein.
J. Rinaldi, L. Otero, Hernán R Bonomi
2026Methods in molecular biology0 citations
Semantic Scholar
Deamidation drives molecular aging of the SARS-CoV-2 spike receptor-binding motif
Ramiro Lorenzo, L. Defelipe, Lucio Aliperti, S. Niebling +10 more
2021bioRxiv0 citations Open access
Semantic Scholar
Crystal structure of Mal de Rio Cuarto virus P9-1 viroplasm protein (C-arm deletion mutant)
G. Llauger, S. Klinke, D. Monti, G. Sycz +4 more
20210 citations
Semantic Scholar
X-ray structural studies on the molecular recognition of innovative β-N- and β-S-galactosides by peanut lectin
L. Otero, Alejandro J. Cagnoni, Emiliano David Primo, S. Klinke +1 more
20200 citations
Semantic Scholar
Peanut lectin complexed with N-beta-D-galactopyranosyl-L-succinamoyl derivative (NGS)
L. Otero, E. Primo, A. Cagnoni, S. Klinke +2 more
20200 citations
Semantic Scholar
Peanut lectin complexed with divalent S-beta-D-thiogalactopyranosyl beta-D-glucopyranoside derivative (diSTGD)
L. Otero, E. Primo, A. Cagnoni, M. E. Cano +3 more
20200 citations
Semantic Scholar
Full length LOV-PAS-HK construct from the LOV-HK sensory protein from Brucella abortus (light-adapted, construct 15-489)
J. Rinaldi, L. Otero, I. Fernández, F. Goldbaum +3 more
20200 citations
Semantic Scholar
LOV-PAS construct from the LOV-HK sensory protein from Brucella abortus (dark-adapted, construct 15-273)
J. Rinaldi, L. Otero, I. Fernández, F. Goldbaum +3 more
20200 citations
Semantic Scholar
Crystal structure of the dark-adapted full-length bacteriophytochrome XccBphP from Xanthomonas campestris in the Pr state bound to BV chromophore
L. Otero, S. Sirigu, S. Klinke, F. Goldbaum +3 more
20200 citations
Semantic Scholar

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