Youngshil Pak

Most-cited papers

1. Inducible costimulator promotes helper T-cell differentiation through phosphoinositide 3-kinase

   M. Gigoux, J. Shang, Youngshil Pak, Ming-Hong Xu +3 more

   2009Proceedings of the National Academy of Sciences of the United States of America242 citations Open access

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2. Transport of LAPTM5 to lysosomes requires association with the ubiquitin ligase Nedd4, but not LAPTM5 ubiquitination

   Youngshil Pak, Wioletta K. Glowacka, M. Bruce, N. Pham +1 more

   2006Journal of Cell Biology114 citations Open access

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3. Agonist-induced Desensitization of the μ Opioid Receptor Is Determined by Threonine 394 Preceded by Acidic Amino Acids in the COOH-terminal Tail*

   Youngshil Pak, B. O'Dowd, S. George

   1997Journal of Biological Chemistry86 citations Open access

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4. Agonist-induced functional desensitization of the mu-opioid receptor is mediated by loss of membrane receptors rather than uncoupling from G protein.

   Youngshil Pak, A. Kouvelas, M. Scheideler, J. Rasmussen +2 more

   1996Molecular Pharmacology79 citations

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5. Agonist-induced, G protein-dependent and -independent down-regulation of the mu opioid receptor. The receptor is a direct substrate for protein-tyrosine kinase.

   Youngshil Pak, B. O'Dowd, Jia-Bei Wang, Susan R. George

   1999Journal of Biological Chemistry78 citations Open access

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6. Direct Binding of the β1 Adrenergic Receptor to the Cyclic AMP-Dependent Guanine Nucleotide Exchange Factor CNrasGEF Leads to Ras Activation

   Youngshil Pak, N. Pham, D. Rotin

   2002Molecular and Cellular Biology72 citations Open access

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7. Role for the C-terminus in agonist-induced mu opioid receptor phosphorylation and desensitization.

   Hong Deng, Yunkai Yu, Youngshil Pak, B. O'Dowd +4 more

   2000Biochemistry71 citations

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8. Regulation of Commissureless by the Ubiquitin Ligase DNedd4 Is Required for Neuromuscular Synaptogenesis in Drosophila melanogaster

   Bryant Ing, A. Shteiman-Kotler, M. Castelli, Pauline C. Henry +4 more

   2006Molecular and Cellular Biology43 citations Open access

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9. The Guanine Nucleotide Exchange Factor CNrasGEF Regulates Melanogenesis and Cell Survival in Melanoma Cells*

   Eva M. Amsen, N. Pham, Youngshil Pak, D. Rotin

   2006Journal of Biological Chemistry38 citations Open access

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10. Transport of LAPTM 5 to lysosomes requires association with the ubiquitin ligase Nedd 4 , but not LAPTM 5 ubiquitination

    Youngshil Pak, W. Glowacka, M. Bruce, N. Pham +1 more

    20069 citations

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11. Agonist-induced, G Protein-dependent and -independent Down-regulation of the μ Opioid Receptor

    Youngshil Pak, B. O'Dowd, Jia-Bei Wang, S. George

    1999Journal of Biological Chemistry9 citations Open access

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12. Neuromuscular Synaptogenesis in Drosophila

    Bryant Ing, A. Shteiman-Kotler, M. Castelli, Pauline C. Henry +4 more

    20060 citations

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13. CNrasGEF Leads to Ras Activation Guanine Nucleotide Exchange Factor Receptor to the Cyclic AMP-Dependent 1 Adrenergic β Direct Binding of the

    Youngshil Pak, N. Pham, D. Rotin

    20020 citations

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14. Characterization of the mu opioid receptor desensitization mechanisms in a heterologous expression system

    Youngshil Pak

    20000 citations

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