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Angela M. Pierce · SciRah

Researcher profile · Semantic Scholar

Angela M. Pierce

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Angela M. Pierce — researcher profile on SciRah

h-index: 18
Works: 102
Citations: 1,187

Most-cited papers

E2F1 Has Both Oncogenic and Tumor-Suppressive Properties in a Transgenic Model
Angela M. Pierce, Robin Schneider‐Broussard, I. Gimenez-Conti, J. Russell +2 more
1999Molecular and Cellular Biology172 citations Open access
Semantic Scholar
TAM receptor tyrosine kinases: Expression, disease and oncogenesis in the central nervous system
Angela M. Pierce, A. Keating
2013Brain Research69 citations Open access
Semantic Scholar
MerTK inhibition is a novel therapeutic approach for glioblastoma multiforme
Kristina H. Knubel, Ben M. Pernu, A. Sufit, S. Nelson +2 more
2014OncoTarget64 citations Open access
Semantic Scholar
Inhibition of MYC attenuates tumor cell self‐renewal and promotes senescence in SMARCB1‐deficient Group 2 atypical teratoid rhabdoid tumors to suppress tumor growth in vivo
I. Alimova, Angela M. Pierce, Etienne P. Danis, A. Donson +7 more
2019International Journal of Cancer58 citations Open access
Semantic Scholar
MRI-guided focused ultrasound blood–brain barrier opening increases drug delivery and efficacy in a diffuse midline glioma mouse model
Payton J. Martinez, Genna Nault, Jenna Steiner, M. Wempe +10 more
2023Neuro-Oncology Advances53 citations Open access
Semantic Scholar
Asiatic acid induces endoplasmic reticulum stress and apoptotic death in glioblastoma multiforme cells both in vitro and in vivo
C. Kavitha, A. K. Jain, C. Agarwal, Angela M. Pierce +6 more
2014Molecular Carcinogenesis53 citations Open access
Semantic Scholar
Senescence Induced by BMI1 Inhibition Is a Therapeutic Vulnerability in H3K27M-Mutant DIPG
Ilango Balakrishnan, Etienne P. Danis, Angela M. Pierce, Krishnakumar Madhavan +29 more
2020Cell Reports52 citations Open access
Semantic Scholar
The mcm5-bob1 bypass of Cdc7p/Dbf4p in DNA replication depends on both Cdk1-independent and Cdk1-dependent steps in Saccharomyces cerevisiae.
R. Sclafani, M. Tecklenburg, Angela M. Pierce
2002Genetics48 citations
Semantic Scholar
Super elongation complex as a targetable dependency in diffuse midline glioma
N. Dahl, Etienne P. Danis, Ilango Balakrishnan, Dong Wang +10 more
2020bioRxiv39 citations Open access
Semantic Scholar
A novel PLK1 inhibitor onvansertib effectively sensitizes MYC-driven medulloblastoma to radiotherapy.
Dong Wang, Bethany L. Veo, Angela M. Pierce, S. Fosmire +11 more
2021Neuro-Oncology32 citations Open access
Semantic Scholar
Transcriptional control of DNA repair networks by CDK7 regulates sensitivity to radiation in MYC-driven medulloblastoma
Bethany L. Veo, Etienne P. Danis, Angela M. Pierce, Dong Wang +9 more
2020bioRxiv31 citations Open access
Semantic Scholar
MERTK Inhibition Induces Polyploidy and Promotes Cell Death and Cellular Senescence in Glioblastoma Multiforme
A. Sufit, Alisa B. Lee-Sherick, D. DeRyckere, M. Rupji +9 more
2016PLoS ONE29 citations Open access
Semantic Scholar
Nicotine Activates Nuclear Factor of Activated T Cells c2 (NFATc2) and Prevents Cell Cycle Entry in T Cells
A. Frazer-Abel, S. Baksh, S. Fosmire, Derall G Willis +7 more
2004Journal of Pharmacology and Experimental Therapeutics29 citations Open access
Semantic Scholar
Combined functional genomic and chemical screens identify SETD8 as a therapeutic target in MYC-driven medulloblastoma.
Bethany L. Veo, Etienne P. Danis, Angela M. Pierce, Ismail Sola +7 more
2019JCI Insight23 citations Open access
Semantic Scholar
A Regulatory Loop of FBXW7-MYC-PLK1 Controls Tumorigenesis of MYC-Driven Medulloblastoma
Dong Wang, Angela M. Pierce, Bethany L. Veo, S. Fosmire +4 more
2021Cancers20 citations Open access
Semantic Scholar
Venetoclax cooperates with ionizing radiation to attenuate Diffuse Midline Glioma tumor growth.
Krishnakumar Madhavan, Ilango Balakrishnan, S. Lakshmanachetty, Angela M. Pierce +10 more
2022Clinical Cancer Research18 citations Open access
Semantic Scholar
Preclinical and clinical investigation of intratumoral chemotherapy pharmacokinetics in DIPG using gemcitabine
A. Green, Patrick C. Flannery, Todd C. Hankinson, Brent R. O'Neill +19 more
2020Neuro-Oncology Advances18 citations Open access
Semantic Scholar
Proteasome inhibition as a therapeutic approach in atypical teratoid/rhabdoid tumors
Andrew Morin, C. Soane, Angela M. Pierce, Bridget Sanford +5 more
2020Neuro-Oncology Advances16 citations Open access
Semantic Scholar
Establishment of patient-derived orthotopic xenograft model of 1q+ posterior fossa group A ependymoma.
Angela M. Pierce, Davis A Witt, A. Donson, A. Gilani +16 more
2019Neuro-Oncology16 citations Open access
Semantic Scholar
Targeting Polo-like kinase 1 in SMARCB1 deleted atypical teratoid rhabdoid tumor
I. Alimova, Angela M. Pierce, Peter S. Harris, A. Donson +8 more
2017OncoTarget16 citations Open access
Semantic Scholar
Creating Anatomically Accurate and Reproducible Intracranial Xenografts of Human Brain Tumors
Angela M. Pierce, A. Keating
2014Journal of Visualized Experiments16 citations Open access
Semantic Scholar
Targeting MYC-Driven Replication Stress in Medulloblastoma with AZD1775 and Gemcitabine
Daniel C. Moreira, S. Venkataraman, A. Subramanian, J. DeSisto +8 more
2020Journal of Neuro-Oncology14 citations Open access
Semantic Scholar
Increased E 2 F 1 activity induces skin tumors in mice heterozygous and nullizygous for p 53
Angela M. Pierce, I. Gimenez-Conti, Robin Schneider‐Broussard, L. A. Martinez +2 more
199814 citations
Semantic Scholar
EYA2 Tyrosine Phosphatase Inhibition Reduces MYC and Prevents Medulloblastoma Progression.
Arthur Wolin, M. Vincent, Taylor J. Hotz, S. Purdy +18 more
2023Neuro-Oncology11 citations Open access
Semantic Scholar
Single-cell multi-omics identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma
Bethany L. Veo, Dong Wang, J. DeSisto, Angela M. Pierce +8 more
2025Nature Communications10 citations Open access
Semantic Scholar
Targeting the TP53/MDM2 axis enhances radiation sensitivity in atypical teratoid rhabdoid tumors
I. Alimova, Dong Wang, Etienne P. Danis, Angela M. Pierce +9 more
2022International Journal of Oncology9 citations Open access
Semantic Scholar
Development of chromosome 1q+ specific treatment for highest risk pediatric posterior fossa ependymoma
A. Griesinger, Annaliese J. Calzadilla, Enrique Grimaldo, A. Donson +13 more
2024Clinical Cancer Research8 citations
Semantic Scholar
The PARP inhibitor Rucaparib synergizes with radiation to attenuate atypical teratoid rhabdoid tumor growth.
I. Alimova, G. Murdock, Angela M. Pierce, Dong Wang +4 more
2023Neuro-Oncology Advances8 citations Open access
Semantic Scholar
Targeting processive transcription for Myc-driven circuitry in medulloblastoma
L. M. Sobral, Faye Walker, Krishnakumar Madhavan, Elizabeth Janko +14 more
2025Neuro-Oncology5 citations Open access
Semantic Scholar
Rapid P-TEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy
Faye Walker, L. M. Sobral, Etienne P. Danis, Bridget Sanford +12 more
2024Nature Communications5 citations Open access
Semantic Scholar
Transcriptional regulation of protein synthesis by mediator kinase represents a therapeutic vulnerability in MYC-driven medulloblastoma
Dong Wang, Caitlin Ritz, Yuhuan Luo, Ammu Suresh +11 more
2025Nature Communications4 citations Open access
Semantic Scholar
MEDU-13. FUNCTIONAL CRISPR-CAS9 SCREEN IDENTIFIES DRUGGABLE DEPENDENCIES IN MYC-DRIVEN MEDULLOBLASTOMA
Bethany L. Veo, S. Fosmire, Dong Wang, Krishnakumar Madhavan +3 more
2019Neuro-Oncology3 citations Open access
Semantic Scholar
SIRT2 regulates the SMARCB1 loss-driven differentiation block in ATRT
Irina Alimova, Dong Wang, J. DeSisto, Etienne P. Danis +12 more
2025Molecular Cancer Research2 citations
Semantic Scholar
Abstract PR010: Developing a safe and potent tumor-targeting gated CAR-T cell therapy for DIPG: A deadly pediatric brain tumor
S. Venkataraman, Ilango Balakrishnan, Lillie Leach, Krishnakumar Madhavan +7 more
2024Cancer Research2 citations
Semantic Scholar
Transcriptional Regulation of Protein Synthesis by Mediator Kinase Represents a Therapeutic Vulnerability in MYC-driven Medulloblastoma
Rajeev Vibhakar, Dong Wang, Caitlin Ritz, Angela M. Pierce +11 more
2024Research Square2 citations Open access
Semantic Scholar
EXPERIMENTAL THERAPEUTICS AND PHARMACOLOGY
C. Aaberg-Jessen, Louise Fogh, Bo Halle, V. Jensen +496 more
20132 citations Open access
Semantic Scholar
Development of an Anti-CD99 Antibody Enables Targeting of Diffuse Midline Glioma
Ilango Balakrishnan, Krishnakumar Madhavan, Angela M. Pierce, Joshua Michlin +17 more
2025Cancer Research1 citations
Semantic Scholar
Targeting processive transcription for Myc-driven circuitry in medulloblastoma
Lays Martin Sobral, Faye Walker, Krishnakumar Madhavan, Elizabeth Janko +12 more
2025bioRxiv1 citations Open access
Semantic Scholar
Targeting Diffuse Midline Glioma with a novel anti-CD99 Antibody
Ilango Balakrishnan, Krishnakumar Madhavan, Angela M. Pierce, Joshua Michlin +13 more
2024bioRxiv1 citations Open access
Semantic Scholar
Single-cell multi-omics analysis identifies metabolism-linked epigenetic reprogramming as a driver of therapy-resistant medulloblastoma
Rajeev Vibhakar, Bethany L. Veo, Dong Wang, J. DeSisto +1 more
2024Research Square1 citations
Semantic Scholar
EPEN-08. COMBINED PDGFR INHIBITOR AXITINIB AND RETINOID TRETINOIN DECREASES PROLIFERATION AND HIGH-RISK NEOPLASTIC SUBPOPULATION PROPORTIONS PFA EPENDYMOMA
A. Donson, Enrique Grimaldo, K. Riemondy, A. Griesinger +4 more
2023Neuro-Oncology1 citations Open access
Semantic Scholar
SURG-05. MRI-GUIDED FOCUSED ULTRASOUND BLOOD-BRAIN BARRIER DISRUPTION INCREASES DRUG DELIVERY AND EFFICACY IN AN ORTHOTOPIC DIPG MODEL
Payton J. Martinez, Genna Nault, Jenna Steiner, Michael F. Wempe +10 more
2023Neuro-Oncology1 citations Open access
Semantic Scholar
MDB-26. CDK8 IS AN ONCOGENE IN GROUP 3 MEDULLOBLASTOMA THAT IMPACTS PROTEIN TRANSLATION BY REGULATING THE TRANSCRIPTIONAL ACTIVITY OF RIBOSOMAL GENES
Dong Wang, Bethany L. Veo, Angela M. Pierce, Caitlin Ritz +1 more
2023Neuro-Oncology1 citations Open access
Semantic Scholar
DIPG-32. PRECLINICAL TESTING OF THE EFFICACY AND SAFETY OF CRISPR/CAS9 GENE EDITED CAR-T CELL THERAPY FOR DIFFUSE MIDLINE GLIOMA (DMG)
Ilango Balakrishnan, Lillie Leach, Angela M. Pierce, S. Lakshmanachetty +8 more
2023Neuro-Oncology1 citations Open access
Semantic Scholar
Rapid PTEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy
Faye Walker, L. M. Sobral, Etienne P. Danis, Bridget Sanford +10 more
2023bioRxiv1 citations Open access
Semantic Scholar
EPEN-26. Chemokine receptor blockade reverses CCL2 mediated immunosuppression and restores CAR-T cell function in posterior fossa ependymoma
Allison P. Cole, A. Donson, Angela M. Pierce, Enrique Grimaldo +7 more
2022Neuro-Oncology1 citations Open access
Semantic Scholar
ATRT-23. SIRT2 cooperates with SMARCB1 to induce a differentiation block in ATRT
I. Alimova, Dong Wang, Angela M. Pierce, S. Lakshmanachetty +10 more
2022Neuro-Oncology1 citations Open access
Semantic Scholar
MODL-01. SAFETY IN CONCOMITANT USE OF MEK AND BRAF INHIBITORS WITH BEVACIZUMAB
A. Abdel-Hafiz, Krishnakumar Madhavan, Ilango Balakrishnan, Angela M. Pierce +5 more
2020Neuro-Oncology1 citations Open access
Semantic Scholar
PHRM-02. DELIVERY OF CHEMOTHERAPEUTICS TO PEDIATRIC BRAIN TUMORS USING CITRATE-CAPPED GOLD NANOPARTICLES
Krishnakumar Madhavan, Ilango Balakrishnan, Angela M. Pierce, S. Venkataraman +1 more
2018Neuro-Oncology1 citations Open access
Semantic Scholar
AT-04TARGETING Myc DRIVEN TRANSCRIPTIONAL OUTPUT IN ATYPICAL TERATOID RHABDOID TUMOR.
I. Alimova, S. Venkataraman, Angela M. Pierce, Andrea Greisinger +4 more
20151 citations Open access
Semantic Scholar

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Rajeev Vibhakar×37
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Rajeev Vibhakar — researcher profile on SciRah
S. Venkataraman×30
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S. Venkataraman — researcher profile on SciRah
Ilango Balakrishnan×20
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Ilango Balakrishnan — researcher profile on SciRah
Etienne P. Danis×18
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Etienne P. Danis — researcher profile on SciRah

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Krishnakumar Madhavan×16

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A. Donson — researcher profile on SciRah

Bethany L. Veo×13

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Bethany L. Veo — researcher profile on SciRah

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Dong Wang — researcher profile on SciRah

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N. Serkova — researcher profile on SciRah

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Breauna Brunt — researcher profile on SciRah

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