Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Mathieu · SciRah

Researcher profile · Semantic Scholar

S. Mathieu

Share profile

S. Mathieu — researcher profile on SciRah

h-index: 18
Works: 39
Citations: 1,471

Most-cited papers

Discovery of a potent, selective, and orally available class I phosphatidylinositol 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) kinase inhibitor (GDC-0980) for the treatment of cancer.
D. Sutherlin, Linda Bao, M. Berry, G. Castanedo +27 more
2011Journal of Medicinal Chemistry210 citations Open access
Semantic Scholar
Discovery of Orally Active Inhibitors of Brahma Homolog (BRM)/SMARCA2 ATPase Activity for the Treatment of Brahma Related Gene 1 (BRG1)/SMARCA4-Mutant Cancers.
Julien P. N. Papillon, Katsumasa Nakajima, Christopher D. Adair, J. Hempel +32 more
2018Journal of Medicinal Chemistry203 citations Open access
Semantic Scholar
Identification of TNO155, an Allosteric SHP2 Inhibitor for the Treatment of Cancer.
M. LaMarche, M. Acker, A. Argintaru, D. Bauer +61 more
2020Journal of Medicinal Chemistry187 citations Open access
Semantic Scholar
Discovery of (thienopyrimidin-2-yl)aminopyrimidines as potent, selective, and orally available pan-PI3-kinase and dual pan-PI3-kinase/mTOR inhibitors for the treatment of cancer.
D. Sutherlin, D. Sampath, M. Berry, G. Castanedo +24 more
2010Journal of Medicinal Chemistry121 citations Open access
Semantic Scholar
Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor.
T. Heffron, M. Berry, G. Castanedo, Christine Chang +20 more
2010Bioorganic & Medicinal Chemistry Letters84 citations Open access
Semantic Scholar
Rational design of phosphoinositide 3-kinase α inhibitors that exhibit selectivity over the phosphoinositide 3-kinase β isoform.
T. Heffron, Binqing Wei, A. Olivero, S. Staben +17 more
2011Journal of Medicinal Chemistry63 citations Open access
Semantic Scholar
Pyrazolopyridine Inhibitors of B-Raf(V600E). Part 1: The Development of Selective, Orally Bioavailable, and Efficacious Inhibitors.
S. Wenglowsky, Linjing Ren, K. Ahrendt, Ellen R. Laird +34 more
2011ACS Medicinal Chemistry Letters59 citations Open access
Semantic Scholar
Pyrazolopyridine inhibitors of B-RafV600E. Part 2: structure-activity relationships.
S. Wenglowsky, K. Ahrendt, A. Buckmelter, Bai-Nian Feng +16 more
2011Bioorganic & Medicinal Chemistry Letters50 citations Open access
Semantic Scholar
Electrophilic activation of lactams with Tf2O and pyridine: expedient synthesis of (+/-)-tetraponerine T4.
A. Charette, S. Mathieu, J. Martel
2005Organic Letters50 citations
Semantic Scholar
Diastereoselective zinco-cyclopropanation of chiral allylic alcohols with gem-dizinc carbenoids.
J. Fournier, S. Mathieu, A. Charette
2005Journal of the American Chemical Society48 citations
Semantic Scholar
Toward the Validation of Maternal Embryonic Leucine Zipper Kinase: Discovery, Optimization of Highly Potent and Selective Inhibitors, and Preliminary Biology Insight.
B. Touré, J. Giraldes, T. Smith, E. Sprague +22 more
2016Journal of Medicinal Chemistry46 citations Open access
Semantic Scholar
Mes2GeCPAr: The First Germaphosphaallene
H. Ramdane, Henri Ranaivonjatovo, J. Escudié, S. Mathieu +1 more
199645 citations
Semantic Scholar
Potent and selective aminopyrimidine-based B-Raf inhibitors with favorable physicochemical and pharmacokinetic properties.
S. Mathieu, S. Gradl, Linjing Ren, Zhaoyang Wen +22 more
2012Journal of Medicinal Chemistry42 citations Open access
Semantic Scholar
Expeditive syntheses of functionalized pentahelicenes and NC-AFM on Ag(001).
Sarah Goretta, Christelle Tasciotti, S. Mathieu, Mario Smet +8 more
2009Organic Letters42 citations
Semantic Scholar
Structure-Guided Design of Group I Selective p21-Activated Kinase Inhibitors.
J. Crawford, Wendy B. K. Lee, Ignacio Aliagas, S. Mathieu +15 more
2015Journal of Medicinal Chemistry38 citations Open access
Semantic Scholar
The Discovery of SWI/SNF Chromatin Remodeling Activity as a Novel and Targetable Dependency in Uveal Melanoma
Florencia Rago, GiNell Elliott, Ai-Ling Li, K. Sprouffske +23 more
2020Molecular Cancer Therapeutics26 citations Open access
Semantic Scholar
Discovery of Darovasertib (NVP-LXS196), a Pan-PKC Inhibitor for the Treatment of Metastatic Uveal Melanoma.
Michael Visser, Julien P. N. Papillon, Michael Luzzio, M. LaMarche +23 more
2024Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
Highly potent and selective 3-N-methylquinazoline-4(3H)-one based inhibitors of B-Raf(V600E) kinase.
S. Wenglowsky, Linjing Ren, J. Grina, Joshua D. Hansen +13 more
2014Bioorganic & Medicinal Chemistry Letters18 citations Open access
Semantic Scholar
The discovery of potent and selective pyridopyrimidin-7-one based inhibitors of B-RafV600E kinase.
Linjing Ren, K. Ahrendt, J. Grina, Ellen R. Laird +14 more
2012Bioorganic & Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Paradoxical Increase of Permeability and Lipophilicity with the Increasing Topological Polar Surface Area within a Series of PRMT5 Inhibitors.
U. Argikar, M. Blatter, D. Bednarczyk, Zhuoliang Chen +16 more
2022Journal of Medicinal Chemistry14 citations Open access
Semantic Scholar
Synthesis and evaluation of a series of 4-azaindole-containing p21-activated kinase-1 inhibitors.
Wendy B. K. Lee, J. Crawford, Ignacio Aliagas, Lesley J. Murray +10 more
2016Bioorganic & Medicinal Chemistry Letters14 citations Open access
Semantic Scholar
Leveraging the Pre-DFG Residue Thr-406 To Obtain High Kinase Selectivity in an Aminopyrazole-Type PAK1 Inhibitor Series.
J. Rudolph, Ignacio Aliagas, J. Crawford, S. Mathieu +12 more
2015ACS Medicinal Chemistry Letters12 citations Open access
Semantic Scholar
The Two Conformers of 2,3-Digermabutadiene
C. Jouany, S. Mathieu, M. Chaubon-Deredempt, G. Trinquier
199412 citations
Semantic Scholar
"Addition" and "Subtraction": Selectivity Design for Type II Maternal Embryonic Leucine Zipper Kinase Inhibitors.
Xin Chen, J. Giraldes, E. Sprague, S. Shakya +11 more
2017Journal of Medicinal Chemistry9 citations Open access
Semantic Scholar
Appraising the relative strengths of C-H***O[double bond, length as m-dash]C and N-H***O[double bond, length as m-dash]C interactions from cis-N-methylacetamide multimers.
S. Mathieu, G. Trinquier
2009Physical Chemistry, Chemical Physics - PCCP9 citations
Semantic Scholar
Estimating the "steric clash" at cis peptide bonds.
S. Mathieu, R. Poteau, G. Trinquier
2008Journal of Physical Chemistry B9 citations
Semantic Scholar
In-Depth Characterization and Validation in BRG1-Mutant Lung Cancers Define Novel Catalytic Inhibitors of SWI/SNF Chromatin Remodeling
Zainab Jagani, Gregg Chenail, K. Xiang, Geoffrey Bushold +65 more
2019bioRxiv8 citations Open access
Semantic Scholar
Diastereoselective Synthesis of 1,2,3-Substituted Potassium Cyclopropyl Trifluoroborates via an Unusual Zinc-Boron Exchange
A. Charette, S. Mathieu, J. Fournier
20057 citations Open access
Semantic Scholar
Discovery of Gut-Targeted GPR40 Agonist K-757 and GPR119 Agonist K-833, a Combination Treatment for Metabolic Disorders.
C. Moyes, Shu-Wen He, S. Mathieu, Sara Lehman +24 more
2025Journal of Medicinal Chemistry3 citations
Semantic Scholar
Oxidative addition of carbon dioxide into mesoionics.
S. Mathieu, G. Trinquier
2019Physical Chemistry, Chemical Physics - PCCP3 citations
Semantic Scholar
The -BF-NH- link as a peptide-bond surrogate.
S. Mathieu, G. Trinquier
2012Journal of Physical Chemistry B3 citations
Semantic Scholar
Abstract #2707: Design and synthesis of dual PI3K/mTor inhibitors
A. Olivero, T. Heffron, L. Berry, M. Berry +24 more
20090 citations
Semantic Scholar
RAF inhibitors pyrazolo [3,4-b] pyridine
K. Ahrendt, A. Buckmelter, Jason De Meese, J. Grina +16 more
20090 citations
Semantic Scholar
Pyrazol[3,4-b]pyridin-raf-inhibitoren
K. Ahrendt, A. Buckmelter, Jason De Meese, J. Grina +16 more
20090 citations
Semantic Scholar
Imidazo [4,5-b] pyridine used as RAF inhibitors
K. Ahrendt, A. Buckmelter, J. Grina, Joshua D. Hansen +11 more
20090 citations
Semantic Scholar
Electrophilic Activation of Lactams with Tf2O and Pyridine: Expedient Synthesis of (.+‐.)‐Tetraponerine T4.
A. Charette, S. Mathieu, J. Martel
20060 citations
Semantic Scholar
Diastereoselective Zinco‐Cyclopropanation of Chiral Allylic Alcohols with gem‐Dizinc Carbenoids.
J. Fournier, S. Mathieu, A. Charette
20060 citations
Semantic Scholar
CCDC 600135: Experimental Crystal Structure Determination
A. Charette, S. Mathieu, J. Martel
20060 citations
Semantic Scholar
Diastereoselective Synthesis of 1,2,3-Substituted Potassium Cyclopropyl Trifluoroborates via an Unusual Zinc—Boron Exchange.
A. Charette, S. Mathieu, J. Fournier
20050 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

J. Rudolph×10
Invite
J. Rudolph — researcher profile on SciRah
S. Wenglowsky×8
Invite
S. Wenglowsky — researcher profile on SciRah
Linjing Ren×8
Invite
Linjing Ren — researcher profile on SciRah
Ellen R. Laird×8
Invite
Ellen R. Laird — researcher profile on SciRah

Joshua D. Hansen

×8

Invite

Joshua D. Hansen — researcher profile on SciRah

Invite

J. Grina — researcher profile on SciRah

A. Buckmelter×7

Invite

A. Buckmelter — researcher profile on SciRah

David Moreno×7

Invite

David Moreno — researcher profile on SciRah

Invite

A. Charette — researcher profile on SciRah

Invite

K. Ahrendt — researcher profile on SciRah

Invite

B. Newhouse — researcher profile on SciRah

Zhaoyang Wen×6

Invite

Zhaoyang Wen — researcher profile on SciRah