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M. Hastings · SciRah

Researcher profile · Semantic Scholar

M. Hastings

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M. Hastings — researcher profile on SciRah

h-index: 38
Works: 85
Citations: 5,649

Most-cited papers

Selective Release of MicroRNA Species from Normal and Malignant Mammary Epithelial Cells
Lucy Pigati, Sree C. S. Yaddanapudi, Ravi Iyengar, Dong-Ja Kim +4 more
2010PLoS ONE593 citations Open access
Semantic Scholar
Pre-mRNA splicing in the new millennium.
M. Hastings, A. Krainer
2001Current Opinion in Cell Biology538 citations
Semantic Scholar
Splice-switching antisense oligonucleotides as therapeutic drugs
Mallory A. Havens, M. Hastings
2016Nucleic Acids Research494 citations Open access
Semantic Scholar
Comprehensive splice-site analysis using comparative genomics
N. Sheth, X. Roca, M. Hastings, T. Roeder +2 more
2006Nucleic Acids Research412 citations Open access
Semantic Scholar
Determinants of exon 7 splicing in the spinal muscular atrophy genes, SMN1 and SMN2.
Luca Cartegni, M. Hastings, John A. Calarco, E. de Stanchina +1 more
2006American Journal of Human Genetics314 citations Open access
Semantic Scholar
Gene Therapy Restores Auditory and Vestibular Function in a Mouse Model of Usher Syndrome Type 1c
Bifeng Pan, Charles Askew, Alice Galvin, S. Heman-Ackah +8 more
2017Nature Biotechnology271 citations Open access
Semantic Scholar
Plasma components affect accuracy of circulating cancer-related microRNA quantitation.
Dong-Ja Kim, Sarah D. Linnstaedt, Jaime Palma, J. Park +7 more
2012Journal of Molecular Diagnostics187 citations Open access
Semantic Scholar
Targeting RNA Splicing for Disease Therapy
Mallory A. Havens, D. Duelli, M. Hastings
2013Wiley Interdisciplinary Reviews - RNA168 citations Open access
Semantic Scholar
Control of Pre-mRNA Splicing by the General Splicing Factors PUF60 and U2AF65
M. Hastings, E. Allemand, D. Duelli, M. Myers +1 more
2007PLoS ONE151 citations Open access
Semantic Scholar
Post-transcriptional Regulation of Thyroid Hormone Receptor Expression by cis-Acting Sequences and a Naturally Occurring Antisense RNA*
M. Hastings, H. Ingle, M. Lazar, S. H. Munroe
2000Journal of Biological Chemistry140 citations Open access
Semantic Scholar
Induction of Antagonistic Soluble Decoy Receptor Tyrosine Kinases by Intronic PolyA Activation
Sandra Vorlová, G. Rocco, Clare V Lefave, Francine M. Jodelka +4 more
2011Molecules and Cells139 citations Open access
Semantic Scholar
Altered Ryanodine Receptor Expression in Mild Cognitive Impairment and Alzheimer’s Disease
A. M. Bruno, Jeffrey Y. Huang, D. Bennett, R. Marr +2 more
2011Neurobiology of Aging137 citations Open access
Semantic Scholar
Rescue of hearing and vestibular function in a mouse model of human deafness
Jennifer J. Lentz, Francine M. Jodelka, A. Hinrich, Kate E. McCaffrey +6 more
2013Nature Medicine133 citations Open access
Semantic Scholar
Expression of the thyroid hormone receptor gene, erbAalpha, in B lymphocytes: alternative mRNA processing is independent of differentiation but correlates with antisense RNA levels.
M. Hastings, C. Milcarek, Kathleen Martincic, M. Peterson +1 more
1997Nucleic Acids Research121 citations Open access
Semantic Scholar
Therapeutic correction of ApoER2 splicing in Alzheimer's disease mice using antisense oligonucleotides
A. Hinrich, Francine M. Jodelka, Jennifer L. Chang, Daniella Brutman +9 more
2016EMBO Molecular Medicine104 citations Open access
Semantic Scholar
SCRIB and PUF60 are primary drivers of the multisystemic phenotypes of the 8q24.3 copy-number variant.
A. Dauber, C. Golzio, C. Guénot, Francine M. Jodelka +13 more
2013American Journal of Human Genetics92 citations Open access
Semantic Scholar
A feedback loop regulates splicing of the spinal muscular atrophy-modifying gene, SMN2
Francine M. Jodelka, A. Ebert, D. Duelli, M. Hastings
2010Human Molecular Genetics90 citations Open access
Semantic Scholar
Tetracyclines That Promote SMN2 Exon 7 Splicing as Therapeutics for Spinal Muscular Atrophy
M. Hastings, J. Berniac, Ying-Hsiu Liu, P. Abato +11 more
2009Science Translational Medicine88 citations Open access
Semantic Scholar
Biogenesis of mammalian microRNAs by a non-canonical processing pathway
Mallory A. Havens, Ashley A. Reich, D. Duelli, M. Hastings
2012Nucleic Acids Research82 citations Open access
Semantic Scholar
Moving towards effective therapeutic strategies for Neuronal Ceroid Lipofuscinosis
R. Geraets, S. Koh, M. Hastings, T. Kielian +2 more
2016Orphanet Journal of Rare Diseases79 citations Open access
Semantic Scholar
An LKB1 AT-AC intron mutation causes Peutz-Jeghers syndrome via splicing at noncanonical cryptic splice sites
M. Hastings, N. Resta, D. Traum, A. Stella +2 more
2005Nature Structural &Molecular Biology76 citations
Semantic Scholar
Neurite Collapse and Altered ER Ca2+ Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation
J. Korecka, S. Talbot, Teresia M. Osborn, Sherida M. de Leeuw +10 more
2018Stem Cell Reports70 citations Open access
Semantic Scholar
Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts.
J. Korecka, Ria Thomas, D. P. Christensen, A. Hinrich +5 more
2019Human Molecular Genetics61 citations Open access
Semantic Scholar
Drosha Promotes Splicing of a Pre-microRNA-like Alternative Exon
Mallory A. Havens, Ashley A. Reich, M. Hastings
2014PLoS Genetics55 citations Open access
Semantic Scholar
Alternative splicing regulation by interaction of phosphatase PP2Cγ with nucleic acid–binding protein YB-1
E. Allemand, M. Hastings, M. Murray, M. Myers +1 more
2007Nature Structural &Molecular Biology55 citations
Semantic Scholar
Targeting SR Proteins Improves SMN Expression in Spinal Muscular Atrophy Cells
Claribel D Wee, Mallory A. Havens, Francine M. Jodelka, M. Hastings
2014PLoS ONE54 citations Open access
Semantic Scholar
Antisense oligonucleotide-mediated correction of CFTR splicing improves chloride secretion in cystic fibrosis patient-derived bronchial epithelial cells
W. Michaels, R. Bridges, M. Hastings
2020bioRxiv51 citations Open access
Semantic Scholar
Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse
Frederic F. S. Depreux, Lingyan Wang, Han Jiang, Francine M. Jodelka +5 more
2016Nucleic Acids Research50 citations Open access
Semantic Scholar
Differential 3' splice site recognition of SMN1 and SMN2 transcripts by U2AF and U2 snRNP.
Mafalda Martins de Araújo, S. Bonnal, M. Hastings, A. Krainer +1 more
2009RNA: A publication of the RNA Society50 citations Open access
Semantic Scholar
Direct Delivery of Antisense Oligonucleotides to the Middle and Inner Ear Improves Hearing and Balance in Usher Mice
Jennifer J. Lentz, Bifeng Pan, Abhilash Ponnath, Christopher M. Tran +13 more
2020Molecular Therapy46 citations Open access
Semantic Scholar
Rescue of Outer Hair Cells with Antisense Oligonucleotides in Usher Mice Is Dependent on Age of Treatment
Abhilash Ponnath, Frederic F. S. Depreux, Francine M. Jodelka, F. Rigo +3 more
2017Journal of the Association for Research in Otolaryngology46 citations Open access
Semantic Scholar
Therapeutic efficacy of antisense oligonucleotides in mouse models of CLN3 Batten disease
Jessica L. Centa, Francine M. Jodelka, A. Hinrich, Tyler B. Johnson +6 more
2020Nature Medicine45 citations Open access
Semantic Scholar
Sensitive PCR-Based Quantitation of Cell-Free Circulating MicroRNAs
M. Hastings, Jaime Palma, D. Duelli
2012Methods45 citations Open access
Semantic Scholar
Dual-specificity splice sites function alternatively as 5′ and 3′ splice sites
Chao-Lin Zhang, M. Hastings, A. Krainer, Michael Q. Zhang
2007Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice
J. Korecka, Ria Thomas, A. Hinrich, Alyssa Moskites +4 more
2020Molecular Therapy: Nucleic Acids43 citations Open access
Semantic Scholar
RNA localization and co‐translational interactions control RAB13 GTPase function and cell migration
Konstadinos Moissoglu, Michael Stueland, A. Gasparski, Tianhong Wang +3 more
2020EMBO Journal43 citations Open access
Semantic Scholar
Targeting Amyloid-β Precursor Protein, APP, Splicing with Antisense Oligonucleotides Reduces Toxic Amyloid-β Production.
Jennifer L. Chang, A. Hinrich, Brandon Roman, Michaela Norrbom +4 more
2018Molecular Therapy42 citations Open access
Semantic Scholar
Rescue of peripheral vestibular function in Usher syndrome mice using a splice-switching antisense oligonucleotide
Sarath Vijayakumar, Frederic F. S. Depreux, Francine M. Jodelka, Jennifer J. Lentz +3 more
2017Human Molecular Genetics38 citations Open access
Semantic Scholar
Fetal antisense oligonucleotide therapy for congenital deafness and vestibular dysfunction
Lingyan Wang, J. Kempton, Han Jiang, Francine M. Jodelka +6 more
2020Nucleic Acids Research36 citations Open access
Semantic Scholar
A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD
S. Parnell, B. Magenheimer, R. Maser, T. Pavlov +7 more
2018Human Molecular Genetics34 citations Open access
Semantic Scholar
Antisense oligonucleotide therapy rescues disruptions in organization of exploratory movements associated with Usher syndrome type 1C in mice
Tia N. Donaldson, K. Jennings, Lucia A. Cherep, Adam M. McNeela +4 more
2017Behavioural Brain Research27 citations Open access
Semantic Scholar
Ensemble Analysis of Primary miRNA Structure Reveals an Extensive Capacity to Deform near the Drosha Cleavage Site
K. Quarles, Debashish Sahu, Mallory A. Havens, Ellen R Forsyth +3 more
2013Biochemistry27 citations Open access
Semantic Scholar
Fetal gene therapy and pharmacotherapy to treat congenital hearing loss and vestibular dysfunction
M. Hastings, J. Brigande
2020Hearing Research26 citations Open access
Semantic Scholar
The effects of human milk fortification on nutrients and milk properties
R. Donovan, S. G. Kelly, P. Prazad, Pooja Talaty +3 more
2017Journal of Perinatology26 citations
Semantic Scholar
Corticosteroid Sensitization Drives Opioid Addiction
Stephanie A. Carmack, Janaina C. M. Vendruscolo, M. A. McGinn, Jorge Miranda-Barrientos +17 more
2022Molecular Psychiatry23 citations Open access
Semantic Scholar
MicroRNAs are exported from malignant cells in customized particles
Jaime Palma, Sree C. S. Yaddanapudi, Lucy Pigati, Mallory A. Havens +6 more
2012Nucleic Acids Research23 citations Open access
Semantic Scholar
Open reading frame correction using splice-switching antisense oligonucleotides for the treatment of cystic fibrosis
W. Michaels, C. Pena-Rasgado, R. Kotaria, R. Bridges +1 more
2022Proceedings of the National Academy of Sciences of the United States of America21 citations Open access
Semantic Scholar
Antisense Oligonucleotides for the Treatment of Inner Ear Dysfunction
M. Hastings, T. Jones
2019Neurotherapeutics21 citations Open access
Semantic Scholar
RNA therapeutics
M. Hastings, A. Krainer
2023RNA: A publication of the RNA Society19 citations Open access
Semantic Scholar
Alternative splicing regulation by interaction of phosphatase PP2Cgamma with nucleic acid-binding protein YB-1.
E. Allemand, M. Hastings, M. Murray, M. Myers +1 more
2007Nature Structural & Molecular Biology19 citations
Semantic Scholar

Frequent co-authors

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Francine M. Jodelka×17
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Francine M. Jodelka — researcher profile on SciRah
A. Krainer×11
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A. Krainer — researcher profile on SciRah
D. Duelli×10
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D. Duelli — researcher profile on SciRah
F. Rigo×9
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F. Rigo — researcher profile on SciRah

Mallory A. Havens

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Mallory A. Havens — researcher profile on SciRah

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A. Hinrich — researcher profile on SciRah

Jennifer J. Lentz×7

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Jennifer J. Lentz — researcher profile on SciRah

Frederic F. S. Depreux×4

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Frederic F. S. Depreux — researcher profile on SciRah

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Jaime Palma — researcher profile on SciRah

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E. Allemand — researcher profile on SciRah

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M. Myers — researcher profile on SciRah

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H. Farris — researcher profile on SciRah